Hemojuvelin is a novel suppressor for Duchenne muscular dystrophy and age‐related muscle wasting

RGMa mediates reactive astrogliosis and glial scar formation through TGFβ1/Smad2/3 signaling after stroke

(2018) Rongrong Zhang et al.   CELL DEATH AND DIFFERENTIATION

Muscular Dystrophies

(2018) John C. Carter et al.   CLINICS IN CHEST MEDICINE

Sarcopenia: assessment of disease burden and strategies to improve outcomes

(2018) Ilaria Liguori et al.   Clinical Interventions in Aging

Combined Therapies for Duchenne Muscular Dystrophy to Optimize Treatment Efficacy

(2018) Gonzalo Cordova et al.   Frontiers in Genetics

Variable expressivity of HJV related hemochromatosis: “Juvenile” hemochromatosis?

(2018) Houda Hamdi-Rozé et al.   BLOOD CELLS MOLECULES AND DISEASES

Characterization of ferroptosis in murine models of hemochromatosis

(2017) Hao Wang et al.   HEPATOLOGY

Ethical guidelines for publishing in the journal of cachexia, sarcopenia and muscle: update 2017

(2017) Stephan von Haehling et al.   Journal of Cachexia Sarcopenia and Muscle

Targeting TGF-β Mediated SMAD Signaling for the Prevention of Fibrosis

(2017) Kelly L. Walton et al.   Frontiers in Pharmacology

Hemojuvelin regulates the innate immune response to peritoneal bacterial infection in mice

(2017) Qian Wu et al.   Cell Discovery

HJV and HFE Play Distinct Roles in Regulating Hepcidin

(2015) Qian Wu et al.   ANTIOXIDANTS & REDOX SIGNALING

Muscle wasting in disease: molecular mechanisms and promising therapies

(2015) Shenhav Cohen et al.   NATURE REVIEWS DRUG DISCOVERY

Skeletal Muscle: A Brief Review of Structure and Function

(2014) Walter R. Frontera et al.   CALCIFIED TISSUE INTERNATIONAL

TGFβ and BMP signaling in skeletal muscle: potential significance for muscle-related disease

(2014) Roberta Sartori et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Understanding the Process of Fibrosis in Duchenne Muscular Dystrophy

(2014) Yacine Kharraz et al.   Biomed Research International

Nitric Oxide Controls Fat Deposition in Dystrophic Skeletal Muscle by Regulating Fibro-Adipogenic Precursor Differentiation

(2013) Nicoletta Cordani et al.   STEM CELLS

The hemochromatosis proteins HFE, TfR2, and HJV form a membrane-associated protein complex for hepcidin regulation

(2012) Flavia D’Alessio et al.   JOURNAL OF HEPATOLOGY

Targeting the TGFβ signalling pathway in disease

(2012) Rosemary J. Akhurst et al.   NATURE REVIEWS DRUG DISCOVERY

Skeletal muscle hemojuvelin is dispensable for systemic iron homeostasis

(2011) W. Chen et al.   BLOOD

TGF-β/TGF-β receptor system and its role in physiological and pathological conditions

(2011) Juan F. Santibañez et al.   CLINICAL SCIENCE

Conditional disruption of mouse HFE2 gene: Maintenance of systemic iron homeostasis requires hepatic but not skeletal muscle hemojuvelin

(2011) Konstantinos Gkouvatsos et al.   HEPATOLOGY

Betaglycan: A multifunctional accessory

(2011) Maree Bilandzic et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Losartan Restores Skeletal Muscle Remodeling and Protects Against Disuse Atrophy in Sarcopenia

(2011) T. N. Burks et al.   Science Translational Medicine

Role of TGF-β signaling in inherited and acquired myopathies

(2011) Tyesha N Burks et al.   Skeletal Muscle

Total Skeletal Muscle PGC-1 Deficiency Uncouples Mitochondrial Derangements from Fiber Type Determination and Insulin Sensitivity

(2010) Christoph Zechner et al.   Cell Metabolism

Conserved proximal promoter elements control repulsive guidance molecule c/hemojuvelin (Hfe2) gene transcription in skeletal muscle

(2010) Christopher J. Severyn et al.   GENOMICS

The Role of Hepatocyte Hemojuvelin in the Regulation of Bone Morphogenic Protein-6 and Hepcidin Expressionin Vivo

(2010) An-Sheng Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Targeting Fibrosis in Duchenne Muscular Dystrophy

(2010) Lan Zhou et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Gene therapy for muscular dystrophy: current progress and future prospects

(2009) Capucine Trollet et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Selective binding of RGMc/hemojuvelin, a key protein in systemic iron metabolism, to BMP-2 and neogenin

(2008) Robin Kuns-Hashimoto et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Role of transforming growth factor-β superfamily signaling pathways in human disease

(2008) Kelly J. Gordon et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Hemojuvelin regulates hepcidin expression via a selective subset of BMP ligands and receptors independently of neogenin

(2008) Y. Xia et al.   BLOOD

Imbalance between pSmad3 and Notch induces CDK inhibitors in old muscle stem cells

(2008) Morgan E. Carlson et al.   NATURE