Use of a “Catalytic” Cosolvent, N ,N -Dimethyl Octanamide, Allows the Flow Synthesis of Imatinib with no Solvent Switch
出版年份 2016 全文链接
标题
Use of a “Catalytic” Cosolvent, N
,N
-Dimethyl Octanamide, Allows the Flow Synthesis of Imatinib with no Solvent Switch
作者
关键词
-
出版物
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
Volume 55, Issue 7, Pages 2531-2535
出版商
Wiley
发表日期
2016-01-12
DOI
10.1002/anie.201509922
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- Continuous-Flow Technology-A Tool for the Safe Manufacturing of Active Pharmaceutical Ingredients
- (2015) Bernhard Gutmann et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- A Systems Approach towards an Intelligent and Self-Controlling Platform for Integrated Continuous Reaction Sequences
- (2014) Richard J. Ingham et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Continuous Flow Synthesis of Thieno[2,3-c]isoquinolin-5(4H)-one Scaffold: A Valuable Source of PARP-1 Inhibitors
- (2014) Paolo Filipponi et al. ORGANIC PROCESS RESEARCH & DEVELOPMENT
- Sequential Nitration/Hydrogenation Protocol for the Synthesis of Triaminophloroglucinol: Safe Generation and Use of an Explosive Intermediate under Continuous-Flow Conditions
- (2014) David Cantillo et al. ORGANIC PROCESS RESEARCH & DEVELOPMENT
- Continuous-Flow Synthesis of 1-Substituted Benzotriazoles from Chloronitrobenzenes and Amines in a CN Bond Formation/Hydrogenation/Diazotization/Cyclization Sequence
- (2013) Mao Chen et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Flash chemistry: flow chemistry that cannot be done in batch
- (2013) Jun-ichi Yoshida et al. CHEMICAL COMMUNICATIONS
- Flow chemistry syntheses of natural products
- (2013) Julio C. Pastre et al. CHEMICAL SOCIETY REVIEWS
- A prototype device for evaporation in batch and flow chemical processes
- (2013) Benjamin J. Deadman et al. GREEN CHEMISTRY
- The role of flow in green chemistry and engineering
- (2013) Stephen G. Newman et al. GREEN CHEMISTRY
- Selection of a Greener Set of Solvents Evenly Spread in the Hansen Space by Space-Filling Design
- (2013) Adrien Benazzouz et al. INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
- Applying Flow Chemistry: Methods, Materials, and Multistep Synthesis
- (2013) D. Tyler McQuade et al. JOURNAL OF ORGANIC CHEMISTRY
- Trineopentylphosphine: A Conformationally Flexible Ligand for the Coupling of Sterically Demanding Substrates in the Buchwald–Hartwig Amination and Suzuki–Miyaura Reaction
- (2013) Steven M. Raders et al. JOURNAL OF ORGANIC CHEMISTRY
- A three step continuous flow synthesis of the biaryl unit of the HIV protease inhibitorAtazanavir
- (2013) Luciana Dalla-Vechia et al. ORGANIC & BIOMOLECULAR CHEMISTRY
- Sanofi’s Solvent Selection Guide: A Step Toward More Sustainable Processes
- (2013) Denis Prat et al. ORGANIC PROCESS RESEARCH & DEVELOPMENT
- Flow Chemistry - A Key Enabling Technology for (Multistep) Organic Synthesis
- (2012) Jens Wegner et al. ADVANCED SYNTHESIS & CATALYSIS
- An expeditious synthesis of imatinib and analogues utilising flow chemistry methods
- (2012) Mark D. Hopkin et al. ORGANIC & BIOMOLECULAR CHEMISTRY
- Development of a Continuous Schotten–Baumann Route to an Acyl Sulfonamide
- (2012) Timothy D. White et al. ORGANIC PROCESS RESEARCH & DEVELOPMENT
- Suzuki-Miyaura Cross-Coupling Reactions in Flow: Multistep Synthesis Enabled by a Microfluidic Extraction
- (2011) Timothy Noël et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Deciding Whether To Go with the Flow: Evaluating the Merits of Flow Reactors for Synthesis
- (2011) Ryan L. Hartman et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Recent advances in micro reaction technology
- (2011) Charlotte Wiles et al. CHEMICAL COMMUNICATIONS
- Cross-coupling in flow
- (2011) Timothy Noël et al. CHEMICAL SOCIETY REVIEWS
- Packed-Bed Reactors for Continuous-Flow CN Cross-Coupling
- (2010) John R. Naber et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- A flow-based synthesis of Imatinib: the API of Gleevec
- (2010) Mark D. Hopkin et al. CHEMICAL COMMUNICATIONS
- Continuous flow multi-step organic synthesis
- (2010) Damien Webb et al. Chemical Science
- Palladium-catalyzed amination reactions in flow: overcoming the challenges of clogging via acoustic irradiation
- (2010) Timothy Noël et al. Chemical Science
- Palladium-catalyzed coupling of functionalized primary and secondary amines with aryl and heteroaryl halides: two ligands suffice in most cases
- (2010) Debabrata Maiti et al. Chemical Science
- Dialkylbiaryl phosphines in Pd-catalyzed amination: a user's guide
- (2010) David S. Surry et al. Chemical Science
- Multistep Microchemical Synthesis Enabled by Microfluidic Distillation
- (2009) Ryan L. Hartman et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Evolution of a Fourth Generation Catalyst for the Amination and Thioetherification of Aryl Halides
- (2008) John F. Hartwig ACCOUNTS OF CHEMICAL RESEARCH
- Liquid–liquid two-phase flow patterns and mass transfer characteristics in rectangular glass microreactors
- (2008) Anne-Laure Dessimoz et al. CHEMICAL ENGINEERING SCIENCE
- Pd-Catalyzed Aryl Amination Mediated by Well Defined, N-Heterocyclic Carbene (NHC)–Pd Precatalysts, PEPPSI
- (2008) Michael G. Organ et al. CHEMISTRY-A EUROPEAN JOURNAL
- A Highly Active Catalyst for Pd-Catalyzed Amination Reactions: Cross-Coupling Reactions Using Aryl Mesylates and the Highly Selective Monoarylation of Primary Amines Using Aryl Chlorides
- (2008) Brett P. Fors et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Sonogashira Couplings of Aryl Bromides: Room Temperature, Water Only, No Copper
- (2008) Bruce H. Lipshutz et al. ORGANIC LETTERS
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started