Adenosine deaminase-1 delineates human follicular helper T cell function and is altered with HIV

Human Monocyte Subsets Are Transcriptionally and Functionally Altered in Aging in Response to Pattern Recognition Receptor Agonists

(2017) Talibah U. Metcalf et al.   JOURNAL OF IMMUNOLOGY

T follicular helper (Tfh) cells in lupus: Activation and involvement in SLE pathogenesis

(2016) Patrick Blanco et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

The GSProtein-coupled A2a Adenosine Receptor Controls T Cell Help in the Germinal Center

(2016) Robert K. Abbott et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Germinal Center Hypoxia Potentiates Immunoglobulin Class Switch Recombination

(2016) Robert K. Abbott et al.   JOURNAL OF IMMUNOLOGY

Cutting Edge: Adenosine A2a Receptor Signals Inhibit Germinal Center T Follicular Helper Cell Differentiation during the Primary Response to Vaccination

(2016) Shirdi E. Schmiel et al.   JOURNAL OF IMMUNOLOGY

Germinal centre hypoxia and regulation of antibody qualities by a hypoxia response system

(2016) Sung Hoon Cho et al.   NATURE

T follicular helper cells, interleukin-21 and systemic lupus erythematosus

(2016) Noémie Gensous et al.   RHEUMATOLOGY

Direct Probing of Germinal Center Responses Reveals Immunological Features and Bottlenecks for Neutralizing Antibody Responses to HIV Env Trimer

(2016) Colin Havenar-Daughton et al.   Cell Reports

ICOS+PD-1+CXCR3+ T follicular helper cells contribute to the generation of high-avidity antibodies following influenza vaccination

(2016) Salah-Eddine Bentebibel et al.   Scientific Reports

Global analyses revealed age-related alterations in innate immune responses after stimulation of pathogen recognition receptors

(2015) Talibah U. Metcalf et al.   AGING CELL

Reversible Reprogramming of Circulating Memory T Follicular Helper Cell Function during Chronic HIV Infection

(2015) Rafael Cubas et al.   JOURNAL OF IMMUNOLOGY

Pathophysiology of T follicular helper cells in humans and mice

(2015) Hideki Ueno et al.   NATURE IMMUNOLOGY

T Follicular Helper Cell Differentiation, Function, and Roles in Disease

(2014) Shane Crotty   IMMUNITY

Phenotype and functions of memory Tfh cells in human blood

(2014) Nathalie Schmitt et al.   TRENDS IN IMMUNOLOGY

Human Circulating PD-1+CXCR3−CXCR5+ Memory Tfh Cells Are Highly Functional and Correlate with Broadly Neutralizing HIV Antibody Responses

(2013) Michela Locci et al.   IMMUNITY

Inadequate T follicular cell help impairs B cell immunity during HIV infection

(2013) Rafael A Cubas et al.   NATURE MEDICINE

Induction of ICOS+CXCR3+CXCR5+ TH Cells Correlates with Antibody Responses to Influenza Vaccination

(2013) S.-E. Bentebibel et al.   Science Translational Medicine

The catalytic site structural gate of adenosine deaminase allosterically modulates ligand binding to adenosine receptors

(2012) Eduard Gracia et al.   FASEB JOURNAL

Interleukin-2 Inhibits Germinal Center Formation by Limiting T Follicular Helper Cell Differentiation

(2012) André Ballesteros-Tato et al.   IMMUNITY

CD4 T follicular helper cell dynamics during SIV infection

(2012) Constantinos Petrovas et al.   JOURNAL OF CLINICAL INVESTIGATION

STAT5 is a potent negative regulator of TFHcell differentiation

(2012) Robert J. Johnston et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Autoimmune Dysregulation and Purine Metabolism in Adenosine Deaminase Deficiency

(2012) Aisha Vanessa Sauer et al.   Frontiers in Immunology

Human Blood CXCR5+CD4+ T Cells Are Counterparts of T Follicular Cells and Contain Specific Subsets that Differentially Support Antibody Secretion

(2011) Rimpei Morita et al.   IMMUNITY

Synthetic double-stranded RNA induces innate immune responses similar to a live viral vaccine in humans

(2011) Marina Caskey et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Late Interleukin-6 Escalates T Follicular Helper Cell Responses and Controls a Chronic Viral Infection

(2011) J. A. Harker et al.   SCIENCE

Sequence and Structural Convergence of Broad and Potent HIV Antibodies That Mimic CD4 Binding

(2011) J. F. Scheid et al.   SCIENCE

Adenosine deaminase potentiates the generation of effector, memory, and regulatory CD4+ T cells

(2010) José M. Martinez-Navio et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Human adenosine deaminase 2 induces differentiation of monocytes into macrophages and stimulates proliferation of T helper cells and macrophages

(2010) A. V. Zavialov et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Immunological dysfunction in HIV-1-infected individuals caused by impairment of adenosine deaminase-induced costimulation of T-cell activation

(2009) José M. Martinez-Navio et al.   IMMUNOLOGY

Conformational change of adenosine deaminase during ligand-exchange in a crystal

(2008) Takayoshi Kinoshita et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Altered intracellular and extracellular signaling leads to impaired T-cell functions in ADA-SCID patients

(2008) B. Cassani et al.   BLOOD

Generation of T Follicular Helper Cells Is Mediated by Interleukin-21 but Independent of T Helper 1, 2, or 17 Cell Lineages

(2008) Roza I. Nurieva et al.   IMMUNITY

Human adenosine deaminase as an allosteric modulator of human A1adenosine receptor: abolishment of negative cooperativity for [3H](R)-pia binding to the caudate nucleus

(2008) Eduard Gracia et al.   JOURNAL OF NEUROCHEMISTRY