Early splicing functions of fission yeast Prp16 and its unexpected requirement for gene Silencing is governed by intronic features

Polymerase pausing induced by sequence-specific RNA-binding protein drives heterochromatin assembly

(2018) Jahan-Yar Parsa et al.   GENES & DEVELOPMENT

Spliceosomal DEAH-Box ATPases Remodel Pre-mRNA to Activate Alternative Splice Sites

(2016) Daniel R. Semlow et al.   CELL

The Fission Yeast Pre-mRNA-processing Factor 18 (prp18+) Has Intron-specific Splicing Functions with Links to G1-S Cell Cycle Progression

(2016) Nagampalli Vijaykrishna et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cryo-EM structure of the spliceosome immediately after branching

(2016) Wojciech P. Galej et al.   NATURE

Mutations in spliceosomal proteins and retina degeneration

(2016) Šárka Růžičková et al.   RNA Biology

Prp8 retinitis pigmentosa mutants cause defects in the transition between the catalytic steps of splicing

(2016) Megan Mayerle et al.   RNA

Prp4 Kinase Grants the License to Splice: Control of Weak Splice Sites during Spliceosome Activation

(2016) Daniela Eckert et al.   PLoS Genetics

BRR2a Affects Flowering Time via FLC Splicing

(2016) Walid Mahrez et al.   PLoS Genetics

A novel mechanism for Prp5 function in prespliceosome formation and proofreading the branch site sequence

(2015) Wen-Wei Liang et al.   GENES & DEVELOPMENT

Diverse mechanisms for spliceosome-mediated 3′ end processing of telomerase RNA

(2015) Ram Kannan et al.   Nature Communications

A missense mutation in the splicing factor geneDHX38is associated with early-onset retinitis pigmentosa with macular coloboma

(2014) Muhammad Ajmal et al.   JOURNAL OF MEDICAL GENETICS

Remodeling of U2-U6 snRNA helix I during pre-mRNA splicing by Prp16 and the NineTeen Complex protein Cwc2

(2014) Rebecca Hogg et al.   NUCLEIC ACIDS RESEARCH

CLUMSY VEIN, the Arabidopsis DEAH-box Prp16 ortholog, is required for auxin-mediated development

(2014) Ryuji Tsugeki et al.   PLANT JOURNAL

The DExD/H-box ATPase Prp2p destabilizes and proofreads the catalytic RNA core of the spliceosome

(2014) A. M. Wlodaver et al.   RNA

Mtr4-like Protein Coordinates Nuclear RNA Processing for Heterochromatin Assembly and for Telomere Maintenance

(2013) Nathan N. Lee et al.   CELL

Stalled Spliceosomes Are a Signal for RNAi-Mediated Genome Defense

(2013) Phillip A. Dumesic et al.   CELL

Structural and Functional Characterization of the N Terminus of Schizosaccharomyces pombe Cwf10

(2013) S. Brent Livesay et al.   EUKARYOTIC CELL

Intronic sequence elements impede exon ligation and trigger a discard pathway that yields functional telomerase RNA in fission yeast

(2013) R. Kannan et al.   GENES & DEVELOPMENT

Dissection of the factor requirements for spliceosome disassembly and the elucidation of its dissociation products using a purified splicing system

(2013) J.-B. Fourmann et al.   GENES & DEVELOPMENT

A conserved ncRNA-binding protein recruits silencing factors to heterochromatin through an RNAi-independent mechanism

(2013) D. B. Marina et al.   GENES & DEVELOPMENT

Splicing Functions and Global Dependency on Fission Yeast Slu7 Reveal Diversity in Spliceosome Assembly

(2013) Shataparna Banerjee et al.   MOLECULAR AND CELLULAR BIOLOGY

Splicing proofreading at 5′ splice sites by ATPase Prp28p

(2013) Fei Yang et al.   NUCLEIC ACIDS RESEARCH

Differential gene and transcript expression analysis of RNA-seq experiments with TopHat and Cufflinks

(2012) Cole Trapnell et al.   Nature Protocols

The splice is right: Guarantors of fidelity in pre-mRNA splicing

(2011) D. S. Horowitz   RNA

Brr2p RNA helicase with a split personality: insights into structure and function: Figure 1

(2010) Daniela Hahn et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Genome-wide analysis of alternative splicing in Chlamydomonas reinhardtii

(2010) Adam Labadorf et al.   BMC GENOMICS

Structural basis for the function of DEAH helicases

(2010) Yangzi He et al.   EMBO REPORTS

Genomic mRNA Profiling Reveals Compensatory Mechanisms for the Requirement of the Essential Splicing Factor U2AF

(2010) V. Sridharan et al.   MOLECULAR AND CELLULAR BIOLOGY

The DEAH Box ATPases Prp16 and Prp43 Cooperate to Proofread 5′ Splice Site Cleavage during Pre-mRNA Splicing

(2010) Prakash Koodathingal et al.   MOLECULAR CELL

Analysis of a genome-wide set of gene deletions in the fission yeast Schizosaccharomyces pombe

(2010) Dong-Uk Kim et al.   NATURE BIOTECHNOLOGY

DEAH-box ATPase Prp16 has dual roles in remodeling of the spliceosome in catalytic steps

(2010) C.-K. Tseng et al.   RNA

Release of SF3 from the intron branchpoint activates the first step of pre-mRNA splicing

(2010) R. M. Lardelli et al.   RNA

TopHat: discovering splice junctions with RNA-Seq

(2009) Cole Trapnell et al.   BIOINFORMATICS

The Spliceosome: Design Principles of a Dynamic RNP Machine

(2009) Markus C. Wahl et al.   CELL

Involvement of the Spliceosomal U4 Small Nuclear RNA in Heterochromatic Gene Silencing at Fission Yeast Centromeres

(2009) Madoka Chinen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cwc25 Is a Novel Splicing Factor Required after Prp2 and Yju2 To Facilitate the First Catalytic Reaction

(2009) Y.-F. Chiu et al.   MOLECULAR AND CELLULAR BIOLOGY

Reconstitution of both steps of Saccharomyces cerevisiae splicing with purified spliceosomal components

(2009) Zbigniew Warkocki et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Evidence that U2/U6 helix I promotes both catalytic steps of pre-mRNA splicing and rearranges in between these steps

(2009) M. A. Mefford et al.   RNA

Ultrafast and memory-efficient alignment of short DNA sequences to the human genome

(2009) Ben Langmead et al.   GENOME BIOLOGY

ATP-dependent unwinding of U4/U6 snRNAs by the Brr2 helicase requires the C terminus of Prp8

(2008) Corina Maeder et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Splicing Factors Facilitate RNAi-Directed Silencing in Fission Yeast

(2008) E. H. Bayne et al.   SCIENCE