TDP-43 regulates site-specific 2′-O-methylation of U1 and U2 snRNAs via controlling the Cajal body localization of a subset of C/D scaRNAs

Modifications in small nuclear RNAs and their roles in spliceosome assembly and function

(2018) Markus T. Bohnsack et al.   BIOLOGICAL CHEMISTRY

Stress-induced Pseudouridylation Alters the Structural Equilibrium of Yeast U2 snRNA Stem II

(2018) Clarisse van der Feltz et al.   JOURNAL OF MOLECULAR BIOLOGY

Landscape of the complete RNA chemical modifications in the human 80S ribosome

(2018) Masato Taoka et al.   NUCLEIC ACIDS RESEARCH

Tdp-43 cryptic exons are highly variable between cell types

(2017) Yun Ha Jeong et al.   Molecular Neurodegeneration

Major hnRNP proteins act as general TDP-43 functional modifiers both in Drosophila and human neuronal cells

(2017) Chiara Appocher et al.   NUCLEIC ACIDS RESEARCH

Orchestrated positioning of post-transcriptional modifications at the branch point recognition region of U2 snRNA

(2017) Svetlana Deryusheva et al.   RNA

Regulatory RNPs: a novel class of ribonucleoproteins that potentially contribute to ribosome heterogeneity

(2017) Aaron R. Poole et al.   Biology Open

TDP-43 stabilises the processing intermediates of mitochondrial transcripts

(2017) Keiichi Izumikawa et al.   Scientific Reports

The inhibition of TDP-43 mitochondrial localization blocks its neuronal toxicity

(2016) Wenzhang Wang et al.   NATURE MEDICINE

An updated human snoRNAome

(2016) Hadi Jorjani et al.   NUCLEIC ACIDS RESEARCH

RNA modification in Cajal bodies

(2016) U. Thomas Meier   RNA Biology

Direct Identification of Human Cellular MicroRNAs by Nanoflow Liquid Chromatography–High-Resolution Tandem Mass Spectrometry and Database Searching

(2015) Hiroshi Nakayama et al.   ANALYTICAL CHEMISTRY

A mass spectrometry-based method for comprehensive quantitative determination of post-transcriptional RNA modifications: the complete chemical structure ofSchizosaccharomyces pomberibosomal RNAs

(2015) Masato Taoka et al.   NUCLEIC ACIDS RESEARCH

A mass spectrometry-based method for direct determination of pseudouridine in RNA

(2015) Yoshio Yamauchi et al.   NUCLEIC ACIDS RESEARCH

Cajal Body Proteins Differentially Affect the Processing of Box C/D scaRNPs

(2015) Isioma I. Enwerem et al.   PLoS One

Conformational dynamics of stem II of the U2 snRNA

(2015) Margaret L. Rodgers et al.   RNA

TDP-43 repression of nonconserved cryptic exons is compromised in ALS-FTD

(2015) J. P. Ling et al.   SCIENCE

Human cell growth regulator Ly-1 antibody reactive homologue accelerates processing of preribosomal RNA

(2014) Naoki Miyazawa et al.   GENES TO CELLS

TDP-43 loss of cellular function through aggregation requires additional structural determinants beyond its C-terminal Q/N prion-like domain

(2014) Mauricio Budini et al.   HUMAN MOLECULAR GENETICS

A day in the life of the spliceosome

(2014) A. Gregory Matera et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Targeting vertebrate intron-encoded box C/D 2′-O-methylation guide RNAs into the Cajal body

(2014) Aline Marnef et al.   NUCLEIC ACIDS RESEARCH

Coilin association with Box C/D scaRNA suggests a direct role for the Cajal body marker protein in scaRNP biogenesis

(2014) I. I. Enwerem et al.   Biology Open

RNA structure analysis of human spliceosomes reveals a compact 3D arrangement of snRNAs at the catalytic core

(2013) Maria Anokhina et al.   EMBO JOURNAL

Molecular basis of UG-rich RNA recognition by the human splicing factor TDP-43

(2013) Peter J Lukavsky et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Identification of truncated forms of U1 snRNA reveals a novel RNA degradation pathway during snRNP biogenesis

(2013) Hideaki Ishikawa et al.   NUCLEIC ACIDS RESEARCH

Post-transcriptional modifications modulate conformational dynamics in human U2-U6 snRNA complex

(2013) K. S. Karunatilaka et al.   RNA

Conformational heterogeneity of the protein-free human spliceosomal U2-U6 snRNA complex

(2013) C. Zhao et al.   RNA

Spliceosome integrity is defective in the motor neuron diseases ALS and SMA

(2012) Hitomi Tsuiji et al.   EMBO Molecular Medicine

Autoregulation of TDP-43 mRNA levels involves interplay between transcription, splicing, and alternative polyA site selection

(2012) S. E. Avendano-Vazquez et al.   GENES & DEVELOPMENT

Structure of the yeast U2/U6 snRNA complex

(2012) J. E. Burke et al.   RNA

FUS-SMN Protein Interactions Link the Motor Neuron Diseases ALS and SMA

(2012) Tomohiro Yamazaki et al.   Cell Reports

RNA targets of TDP-43 identified by UV-CLIP are deregulated in ALS

(2011) Shangxi Xiao et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Characterizing the RNA targets and position-dependent splicing regulation by TDP-43

(2011) James R Tollervey et al.   NATURE NEUROSCIENCE

Post-transcriptional modification of spliceosomal RNAs is normal in SMN-deficient cells

(2011) S. Deryusheva et al.   RNA

In-Gel Digestion for Mass Spectrometric Characterization of RNA from Fluorescently Stained Polyacrylamide Gels

(2010) Masato Taoka et al.   ANALYTICAL CHEMISTRY

TDP-43 regulates its mRNA levels through a negative feedback loop

(2010) Youhna M Ayala et al.   EMBO JOURNAL

Identification of Neuronal RNA Targets of TDP-43-containing Ribonucleoprotein Complexes

(2010) Chantelle F. Sephton et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Altered distributions of Gemini of coiled bodies and mitochondria in motor neurons of TDP-43 transgenic mice

(2010) X. Shan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Spliceosomal snRNA modifications and their function

(2010) John Karijolich et al.   RNA Biology

Spliceosome Structure and Function

(2010) C. L. Will et al.   Cold Spring Harbor Perspectives in Biology

WRAP53 Is Essential for Cajal Body Formation and for Targeting the Survival of Motor Neuron Complex to Cajal Bodies

(2010) Salah Mahmoudi et al.   PLOS BIOLOGY

Knockdown of transactive response DNA-binding protein (TDP-43) downregulates histone deacetylase 6

(2009) Fabienne C Fiesel et al.   EMBO JOURNAL

Sporadic ALS has compartment-specific aberrant exon splicing and altered cell–matrix adhesion biology

(2009) Stuart J. Rabin et al.   HUMAN MOLECULAR GENETICS

Small Cajal Body–specific RNAs of Drosophila Function in the Absence of Cajal Bodies

(2009) Svetlana Deryusheva et al.   MOLECULAR BIOLOGY OF THE CELL

A Conserved WD40 Protein Binds the Cajal Body Localization Signal of scaRNP Particles

(2009) Kazimierz T. Tycowski et al.   MOLECULAR CELL

Single-molecule analysis of protein-free U2–U6 snRNAs

(2009) Zhuojun Guo et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Ariadne: a database search engine for identification and chemical analysis of RNA using tandem mass spectrometry data

(2009) Hiroshi Nakayama et al.   NUCLEIC ACIDS RESEARCH

Functional mapping of the interaction between TDP-43 and hnRNP A2 in vivo

(2009) A. D'Ambrogio et al.   NUCLEIC ACIDS RESEARCH

Structural determinants of the cellular localization and shuttling of TDP-43

(2008) Y. M. Ayala et al.   JOURNAL OF CELL SCIENCE

TDP-43 Mutations in Familial and Sporadic Amyotrophic Lateral Sclerosis

(2008) J. Sreedharan et al.   SCIENCE