Interferon-λ enhances adaptive mucosal immunity by boosting release of thymic stromal lymphopoietin

IFN-λ prevents influenza virus spread from the upper airways to the lungs and limits virus transmission

(2018) Jonas Klinkhammer et al.   eLife

Passively transferred M2e-specific monoclonal antibody reduces influenza A virus transmission in mice

(2018) Annasaheb Kolpe et al.   ANTIVIRAL RESEARCH

Interferon-λ Mediates Non-redundant Front-Line Antiviral Protection against Influenza Virus Infection without Compromising Host Fitness

(2017) Ioanna E. Galani et al.   IMMUNITY

Toll-like receptor 3 in nasal CD103+ dendritic cells is involved in immunoglobulin A production

(2017) H Takaki et al.   Mucosal Immunology

Similarities and differences in the transcriptional control of expression of the mouse TSLP gene in skin epidermis and intestinal epithelium

(2017) Krishna Priya Ganti et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Optimized DNA Vaccine Enhanced by Adjuvant IL28B Induces Protective Immune Responses Against Herpes Simplex Virus Type 2 in Mice

(2017) Yan Zhou et al.   VIRAL IMMUNOLOGY

Follicular Helper T Cells

(2016) Carola G. Vinuesa et al.   Annual Review of Immunology

Immune Cell Profiling of IFN-λ Response Shows pDCs Express Highest Level of IFN-λR1 and Are Directly Responsive via the JAK-STAT Pathway

(2016) Aoife Kelly et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Critical role of TSLP-responsive mucosal dendritic cells in the induction of nasal antigen-specific IgA response

(2016) S Joo et al.   Mucosal Immunology

Interferon-λ: Immune Functions at Barrier Surfaces and Beyond

(2015) Helen M. Lazear et al.   IMMUNITY

IFN-λ resolves inflammation via suppression of neutrophil infiltration and IL-1β production

(2015) Katrina Blazek et al.   JOURNAL OF EXPERIMENTAL MEDICINE

IFN-  is able to augment TLR-mediated activation and subsequent function of primary human B cells

(2015) R. A. de Groen et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Batf3 maintains autoactivation of Irf8 for commitment of a CD8α+ conventional DC clonogenic progenitor

(2015) Gary E Grajales-Reyes et al.   NATURE IMMUNOLOGY

Interferon-λ and interleukin 22 act synergistically for the induction of interferon-stimulated genes and control of rotavirus infection

(2015) Pedro P Hernández et al.   NATURE IMMUNOLOGY

Guarding the frontiers: the biology of type III interferons

(2015) Andreas Wack et al.   NATURE IMMUNOLOGY

Leukocyte-Derived IFN-α/β and Epithelial IFN-λ Constitute a Compartmentalized Mucosal Defense System that Restricts Enteric Virus Infections

(2015) Tanel Mahlakõiv et al.   PLoS Pathogens

An Important Role for Type III Interferon (IFN- /IL-28) in TLR-Induced Antiviral Activity

(2014) N. Ank et al.   JOURNAL OF IMMUNOLOGY

IL-28B is a Key Regulator of B- and T-Cell Vaccine Responses against Influenza

(2014) Adrian Egli et al.   PLoS Pathogens

Type I and Type III Interferons Drive Redundant Amplification Loops to Induce a Transcriptional Signature in Influenza-Infected Airway Epithelia

(2013) Stefania Crotta et al.   PLoS Pathogens

Thymic stromal lymphopoietin is induced by respiratory syncytial virus–infected airway epithelial cells and promotes a type 2 response to infection

(2012) Hai-Chon Lee et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Thymic stromal lymphopoietin (TSLP) acts as a potent mucosal adjuvant for HIV-1 gp140 vaccination in mice

(2011) Griet A. Van Roey et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

The Airway Antigen Sampling System: Respiratory M Cells as an Alternative Gateway for Inhaled Antigens

(2011) Dong-Young Kim et al.   JOURNAL OF IMMUNOLOGY

IFN-  determines the intestinal epithelial antiviral host defense

(2011) J. Pott et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lambda Interferon Renders Epithelial Cells of the Respiratory and Gastrointestinal Tracts Resistant to Viral Infections

(2010) M. Mordstein et al.   JOURNAL OF VIROLOGY

Sensing the outside world: TSLP regulates barrier immunity

(2010) Steven F Ziegler et al.   NATURE IMMUNOLOGY

Comparative ability of IL-12 and IL-28B to regulate Treg populations and enhance adaptive cellular immunity

(2009) M. P. Morrow et al.   BLOOD

Follicular Helper T Cells: Lineage and Location

(2009) Nicolas Fazilleau et al.   IMMUNITY

Strong interferon-inducing capacity of a highly virulent variant of influenza A virus strain PR8 with deletions in the NS1 gene

(2009) G. Kochs et al.   JOURNAL OF GENERAL VIROLOGY

Human interferon-λ3 is a potent member of the type III interferon family

(2008) C Dellgren et al.   GENES AND IMMUNITY

CTA1-M2e-DD: A novel mucosal adjuvant targeted influenza vaccine

(2008) Dubravka Grdic Eliasson et al.   VACCINE

Interferon-λ Contributes to Innate Immunity of Mice against Influenza A Virus but Not against Hepatotropic Viruses

(2008) Markus Mordstein et al.   PLoS Pathogens

IFN-Lambda (IFN-λ) Is Expressed in a Tissue-Dependent Fashion and Primarily Acts on Epithelial Cells In Vivo

(2008) Caroline Sommereyns et al.   PLoS Pathogens