Leukocyte-Derived IFN-α/β and Epithelial IFN-λ Constitute a Compartmentalized Mucosal Defense System that Restricts Enteric Virus Infections

An Important Role for Type III Interferon (IFN- /IL-28) in TLR-Induced Antiviral Activity

(2014) N. Ank et al.   JOURNAL OF IMMUNOLOGY

Differentiated Human Alveolar Type II Cells Secrete Antiviral IL-29 (IFN- 1) in Response to Influenza A Infection

(2014) J. Wang et al.   JOURNAL OF IMMUNOLOGY

Interferon-λ in the Context of Viral Infections: Production, Response and Therapeutic Implications

(2014) Pascale Hermant et al.   Journal of Innate Immunity

Diverse intracellular pathogens activate type III interferon expression from peroxisomes

(2014) Charlotte Odendall et al.   NATURE IMMUNOLOGY

Pathogenic potential of interferon αβ in acute influenza infection

(2014) Sophia Davidson et al.   Nature Communications

Innate cellular responses to rotavirus infection

(2013) G. Holloway et al.   JOURNAL OF GENERAL VIROLOGY

Toll-Like Receptor Expression and Induction of Type I and Type III Interferons in Primary Airway Epithelial Cells

(2013) I. Ioannidis et al.   JOURNAL OF VIROLOGY

Persistent LCMV Infection Is Controlled by Blockade of Type I Interferon Signaling

(2013) J. R. Teijaro et al.   SCIENCE

The Battle between Rotavirus and Its Host for Control of the Interferon Signaling Pathway

(2013) Michelle M. Arnold et al.   PLoS Pathogens

Type I and Type III Interferons Drive Redundant Amplification Loops to Induce a Transcriptional Signature in Influenza-Infected Airway Epithelia

(2013) Stefania Crotta et al.   PLoS Pathogens

HCV Infection Induces a Unique Hepatic Innate Immune Response Associated With Robust Production of Type III Interferons

(2012) Emmanuel Thomas et al.   GASTROENTEROLOGY

Commensal Bacteria Calibrate the Activation Threshold of Innate Antiviral Immunity

(2012) Michael C. Abt et al.   IMMUNITY

Priming of Natural Killer Cells by Nonmucosal Mononuclear Phagocytes Requires Instructive Signals from Commensal Microbiota

(2012) Stephanie C. Ganal et al.   IMMUNITY

The JAK-STAT Pathway at Twenty

(2012) George R. Stark et al.   IMMUNITY

Innate immune response to homologous rotavirus infection in the small intestinal villous epithelium at single-cell resolution

(2012) A. Sen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Age-Dependent TLR3 Expression of the Intestinal Epithelium Contributes to Rotavirus Susceptibility

(2012) Johanna Pott et al.   PLoS Pathogens

Interferon-β and interferon-λ signaling is not affected by interferon-induced refractoriness to interferon-α in vivo

(2011) Zuzanna Makowska et al.   HEPATOLOGY

Hepatitis C virus induces interferon-λ and interferon-stimulated genes in primary liver cultures

(2011) Svetlana Marukian et al.   HEPATOLOGY

Type I interferon signaling limits reoviral tropism within the brain and prevents lethal systemic infection

(2011) Kalen R. Dionne et al.   JOURNAL OF NEUROVIROLOGY

A diverse range of gene products are effectors of the type I interferon antiviral response

(2011) John W. Schoggins et al.   NATURE

IFN-  determines the intestinal epithelial antiviral host defense

(2011) J. Pott et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Type-III interferon, not type-I, is the predominant interferon induced by respiratory viruses in nasal epithelial cells

(2011) Tamaki Okabayashi et al.   VIRUS RESEARCH

Type I interferon: friend or foe?

(2010) Giorgio Trinchieri   JOURNAL OF EXPERIMENTAL MEDICINE

What Have We Learned from the IL28 Receptor Knockout Mouse?

(2010) Markus Mordstein et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Evidence for a Pathophysiological Role of Keratinocyte-Derived Type III Interferon (IFNλ) in Cutaneous Lupus Erythematosus

(2010) Sabine Zahn et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Gene expression in the brain during reovirus encephalitis

(2010) Kenneth L Tyler et al.   JOURNAL OF NEUROVIROLOGY

Lambda Interferon Renders Epithelial Cells of the Respiratory and Gastrointestinal Tracts Resistant to Viral Infections

(2010) M. Mordstein et al.   JOURNAL OF VIROLOGY

Lambda Interferon Is the Predominant Interferon Induced by Influenza A Virus Infection In Vivo

(2010) N. A. Jewell et al.   JOURNAL OF VIROLOGY

Respiratory virus induction of alpha-, beta- and lambda-interferons in bronchial epithelial cells and peripheral blood mononuclear cells

(2009) M. R. Khaitov et al.   ALLERGY

Role of Interferon in Homologous and Heterologous Rotavirus Infection in the Intestines and Extraintestinal Organs of Suckling Mice

(2008) N. Feng et al.   JOURNAL OF VIROLOGY

HIV-Induced Type I Interferon and Tryptophan Catabolism Drive T Cell Dysfunction Despite Phenotypic Activation

(2008) Adriano Boasso et al.   PLoS One

Interferon-λ Contributes to Innate Immunity of Mice against Influenza A Virus but Not against Hepatotropic Viruses

(2008) Markus Mordstein et al.   PLoS Pathogens

IFN-Lambda (IFN-λ) Is Expressed in a Tissue-Dependent Fashion and Primarily Acts on Epithelial Cells In Vivo

(2008) Caroline Sommereyns et al.   PLoS Pathogens

Interferons and viruses: an interplay between induction, signalling, antiviral responses and virus countermeasures

(2007) R. E. Randall et al.   JOURNAL OF GENERAL VIROLOGY