标题
Functions of RNA N6-methyladenosine modification in cancer progression
作者
关键词
RNA N6-methyladenosine modification, Cancer progression, Physiological and pathological processes, Detection approaches, Clinical application
出版物
MOLECULAR BIOLOGY REPORTS
Volume 46, Issue 1, Pages 1383-1391
出版商
Springer Nature
发表日期
2019-02-21
DOI
10.1007/s11033-018-4471-6
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- Cancer statistics, 2018
- (2018) Rebecca L. Siegel et al. CA-A CANCER JOURNAL FOR CLINICIANS
- Overexpression of YTHDF1 is associated with poor prognosis in patients with hepatocellular carcinoma
- (2018) Xianguang Zhao et al. Cancer Biomarkers
- R-2HG Exhibits Anti-tumor Activity by Targeting FTO/m 6 A/MYC/CEBPA Signaling
- (2018) Rui Su et al. CELL
- METTL14 Inhibits Hematopoietic Stem/Progenitor Differentiation and Promotes Leukemogenesis via mRNA m 6 A Modification
- (2018) Hengyou Weng et al. Cell Stem Cell
- ALKBH5 Inhibits Pancreatic Cancer Motility by Decreasing Long Non-Coding RNA KCNK15-AS1 Methylation
- (2018) Yuan He et al. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
- RNA N6-methyladenosine methyltransferase-like 3 promotes liver cancer progression through YTHDF2-dependent posttranscriptional silencing of SOCS2
- (2018) Mengnuo Chen et al. HEPATOLOGY
- Multiple functions of m6A RNA methylation in cancer
- (2018) Yutian Pan et al. Journal of Hematology & Oncology
- FTO regulates the chemo-radiotherapy resistance of cervical squamous cell carcinoma (CSCC) by targeting β-catenin through mRNA demethylation
- (2018) Shun Zhou et al. MOLECULAR CARCINOGENESIS
- Potential link between m 6 A modification and systemic lupus erythematosus
- (2018) Lian-Ju Li et al. MOLECULAR IMMUNOLOGY
- Heterogeneity and specialized functions of translation machinery: from genes to organisms
- (2018) Naomi R. Genuth et al. NATURE REVIEWS GENETICS
- Reading m 6 A in the Transcriptome: m 6 A-Binding Proteins
- (2018) Deepak P. Patil et al. TRENDS IN CELL BIOLOGY
- N6-methyladenosine links RNA metabolism to cancer progression
- (2018) Dongjun Dai et al. Cell Death & Disease
- Mutations in Cytosine-5 tRNA Methyltransferases Impact Mobile Element Expression and Genome Stability at Specific DNA Repeats
- (2018) Bianca Genenncher et al. Cell Reports
- ketu mutant mice uncover an essential meiotic function for the ancient RNA helicase YTHDC2
- (2018) Devanshi Jain et al. eLife
- m6ASNP: a tool for annotating genetic variants by m6A function
- (2018) Shuai Jiang et al. GigaScience
- m 6 A mRNA modifications are deposited in nascent pre-mRNA and are not required for splicing but do specify cytoplasmic turnover
- (2017) Shengdong Ke et al. GENES & DEVELOPMENT
- The epitranscriptome m6A writer METTL3 promotes chemo- and radioresistance in pancreatic cancer cells
- (2017) Kosuke Taketo et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- Genetic alterations of m6A regulators predict poorer survival in acute myeloid leukemia
- (2017) Chau-To Kwok et al. Journal of Hematology & Oncology
- Regulation of m 6 A Transcripts by the 3ʹ→5ʹ RNA Helicase YTHDC2 Is Essential for a Successful Meiotic Program in the Mammalian Germline
- (2017) Magdalena Natalia Wojtas et al. MOLECULAR CELL
- m6A mRNA methylation controls T cell homeostasis by targeting the IL-7/STAT5/SOCS pathways
- (2017) Hua-Bing Li et al. NATURE
- Promoter-bound METTL3 maintains myeloid leukaemia by m6A-dependent translation control
- (2017) Isaia Barbieri et al. NATURE
- Label-free, direct localization and relative quantitation of the RNA nucleobase methylations m6A, m5C, m3U, and m5U by top-down mass spectrometry
- (2017) Heidelinde Glasner et al. NUCLEIC ACIDS RESEARCH
- m6AVar: a database of functional variants involved in m6A modification
- (2017) Yueyuan Zheng et al. NUCLEIC ACIDS RESEARCH
- Essential role of METTL3-mediated m6A modification in glioma stem-like cells maintenance and radioresistance
- (2017) A Visvanathan et al. ONCOGENE
- Evidence for rRNA 2′-O-methylation plasticity: Control of intrinsic translational capabilities of human ribosomes
- (2017) Jenny Erales et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The chemistries and consequences of DNA and RNA methylation and demethylation
- (2017) Franziska R. Traube et al. RNA Biology
- Human m6A writers: Two subunits, 2 roles
- (2017) Xiang Wang et al. RNA Biology
- Sulforaphane-Induced Cell Cycle Arrest and Senescence are accompanied by DNA Hypomethylation and Changes in microRNA Profile in Breast Cancer Cells
- (2017) Anna Lewinska et al. Theranostics
- m 6 A RNA Methylation Regulates the Self-Renewal and Tumorigenesis of Glioblastoma Stem Cells
- (2017) Qi Cui et al. Cell Reports
- Emerging links between m6A and misregulated mRNA methylation in cancer
- (2017) Samie R. Jaffrey et al. Genome Medicine
- Cytosine-5 RNA Methylation Regulates Neural Stem Cell Differentiation and Motility
- (2017) Joana V. Flores et al. Stem Cell Reports
- Determination of DNA and RNA Methylation in Circulating Tumor Cells by Mass Spectrometry
- (2016) Wei Huang et al. ANALYTICAL CHEMISTRY
- A novel algorithm for calling mRNA m6A peaks by modeling biological variances in MeRIP-seq data
- (2016) Xiaodong Cui et al. BIOINFORMATICS
- A hierarchical model for clustering m6A methylation peaks in MeRIP-seq data
- (2016) Xiaodong Cui et al. BMC GENOMICS
- Sequence-specific and Shape-selective RNA Recognition by the Human RNA 5-Methylcytosine Methyltransferase NSun6
- (2016) Tao Long et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- N 6 -Methyladenosine Modification in a Long Noncoding RNA Hairpin Predisposes Its Conformation to Protein Binding
- (2016) Katherine I. Zhou et al. JOURNAL OF MOLECULAR BIOLOGY
- Structural Basis for Cooperative Function of Mettl3 and Mettl14 Methyltransferases
- (2016) Ping Wang et al. MOLECULAR CELL
- Structural basis of N6-adenosine methylation by the METTL3–METTL14 complex
- (2016) Xiang Wang et al. NATURE
- Reversible methylation of m6Am in the 5′ cap controls mRNA stability
- (2016) Jan Mauer et al. NATURE
- m6A RNA methylation promotes XIST-mediated transcriptional repression
- (2016) Deepak P. Patil et al. NATURE
- Hypoxia induces the breast cancer stem cell phenotype by HIF-dependent and ALKBH5-mediated m6A-demethylation of NANOG mRNA
- (2016) Chuanzhao Zhang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- m6A: Signaling for mRNA splicing
- (2016) Samir Adhikari et al. RNA Biology
- Hypoxia-inducible factors regulate pluripotency factor expression by ZNF217- and ALKBH5-mediated modulation of RNA methylation in breast cancer cells
- (2016) Chuanzhao Zhang et al. Oncotarget
- Recent advances in dynamic m6A RNA modification
- (2016) Guangchao Cao et al. Open Biology
- m6A-Driver: Identifying Context-Specific mRNA m6A Methylation-Driven Gene Interaction Networks
- (2016) Song-Yao Zhang et al. PLoS Computational Biology
- N6-methyladenosine of HIV-1 RNA regulates viral infection and HIV-1 Gag protein expression
- (2016) Nagaraja Tirumuru et al. eLife
- 5′ UTR m6A Promotes Cap-Independent Translation
- (2015) Kate D. Meyer et al. CELL
- HNRNPA2B1 Is a Mediator of m6A-Dependent Nuclear RNA Processing Events
- (2015) Claudio R. Alarcón et al. CELL
- N 6-methyladenosine modification in mRNA: machinery, function and implications for health and diseases
- (2015) Arpita Maity et al. FEBS Journal
- A majority of m6A residues are in the last exons, allowing the potential for 3′ UTR regulation
- (2015) Shengdong Ke et al. GENES & DEVELOPMENT
- Cancer stem cells in glioblastoma
- (2015) Justin D. Lathia et al. GENES & DEVELOPMENT
- Structural Basis for the Discriminative Recognition ofN6-Methyladenosine RNA by the Human YT521-B Homology Domain Family of Proteins
- (2015) Chao Xu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- N6-methyladenosine marks primary microRNAs for processing
- (2015) Claudio R. Alarcón et al. NATURE
- Single-nucleotide-resolution mapping of m6A and m6Am throughout the transcriptome
- (2015) Bastian Linder et al. NATURE METHODS
- Acute Myeloid Leukemia
- (2015) Hartmut Döhner et al. NEW ENGLAND JOURNAL OF MEDICINE
- The Pivotal Regulatory Landscape of RNA Modifications
- (2014) Sheng Li et al. Annual Review of Genomics and Human Genetics
- Crystal structure of the YTH domain of YTHDF2 reveals mechanism for recognition of N6-methyladenosine
- (2014) Tingting Zhu et al. CELL RESEARCH
- FTO-dependent demethylation of N6-methyladenosine regulates mRNA splicing and is required for adipogenesis
- (2014) Xu Zhao et al. CELL RESEARCH
- Mammalian WTAP is a regulatory subunit of the RNA N6-methyladenosine methyltransferase
- (2014) Xiao-Li Ping et al. CELL RESEARCH
- Structure of the YTH domain of human YTHDF2 in complex with an m6A mononucleotide reveals an aromatic cage for m6A recognition
- (2014) Fudong Li et al. CELL RESEARCH
- Role of RNA methyltransferases in tissue renewal and pathology
- (2014) Sandra Blanco et al. CURRENT OPINION IN CELL BIOLOGY
- Aberrant methylation of tRNAs links cellular stress to neuro-developmental disorders
- (2014) S. Blanco et al. EMBO JOURNAL
- Structures of Human ALKBH5 Demethylase Reveal a Unique Binding Mode for Specific Single-strandedN6-Methyladenosine RNA Demethylation
- (2014) Chao Xu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Crystal Structures of the Human RNA Demethylase Alkbh5 Reveal Basis for Substrate Recognition
- (2014) Chong Feng et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- A protocol for RNA methylation differential analysis with MeRIP-Seq data and exomePeak R/Bioconductor package
- (2014) Jia Meng et al. METHODS
- Structural basis for selective binding of m6A RNA by the YTHDC1 YTH domain
- (2014) Chao Xu et al. Nature Chemical Biology
- Gene expression regulation mediated through reversible m6A RNA methylation
- (2014) Ye Fu et al. NATURE REVIEWS GENETICS
- Meclofenamic acid selectively inhibits FTO demethylation of m6A over ALKBH5
- (2014) Yue Huang et al. NUCLEIC ACIDS RESEARCH
- Molecular basis for the recognition of methylated adenines in RNA by the eukaryotic YTH domain
- (2014) S. Luo et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Genomic characterization of a Helicobacter pylori isolate from a patient with gastric cancer in China
- (2014) Yuanhai You et al. Gut Pathogens
- Perturbation of m6A Writers Reveals Two Distinct Classes of mRNA Methylation at Internal and 5′ Sites
- (2014) Schraga Schwartz et al. Cell Reports
- N6-methyladenosine-dependent regulation of messenger RNA stability
- (2013) Xiao Wang et al. NATURE
- The bigger picture of FTO—the first GWAS-identified obesity gene
- (2013) Ruth J. F. Loos et al. Nature Reviews Endocrinology
- Method for site-specific detection of m6A nucleoside presence in RNA based on high-resolution melting (HRM) analysis
- (2013) Anna Y. Golovina et al. NUCLEIC ACIDS RESEARCH
- Probing N6-methyladenosine RNA modification status at single nucleotide resolution in mRNA and long noncoding RNA
- (2013) N. Liu et al. RNA
- Comprehensive Analysis of mRNA Methylation Reveals Enrichment in 3′ UTRs and near Stop Codons
- (2012) Kate D. Meyer et al. CELL
- Development of Cell-Active N6-Methyladenosine RNA Demethylase FTO Inhibitor
- (2012) Baoen Chen et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- ALKBH5 Is a Mammalian RNA Demethylase that Impacts RNA Metabolism and Mouse Fertility
- (2012) Guanqun Zheng et al. MOLECULAR CELL
- Topology of the human and mouse m6A RNA methylomes revealed by m6A-seq
- (2012) Dan Dominissini et al. NATURE
- N6-Methyladenosine in nuclear RNA is a major substrate of the obesity-associated FTO
- (2011) Guifang Jia et al. Nature Chemical Biology
- The YTH Domain Is a Novel RNA Binding Domain
- (2010) Zhaiyi Zhang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Spliceosomal snRNA modifications and their function
- (2010) John Karijolich et al. RNA Biology
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