Prohibitin: A hypothetical target for sex-based new therapeutics for metabolic and immune diseases

Estrogen Regulates Mitochondrial Morphology through Phosphorylation of Dynamin-related Protein 1 in MCF7 Human Breast Cancer Cells

(2018) Phyu Synn Oo et al.   ACTA HISTOCHEMICA ET CYTOCHEMICA

Prohibitin: A new player in immunometabolism and in linking obesity and inflammation with cancer

(2018) Yang Xin Zi Xu et al.   CANCER LETTERS

Membrane-initiated estrogen signaling via Gq-coupled GPCR in the central nervous system

(2018) Gwyndolin Vail et al.   STEROIDS

Mitochondrial damage and iron metabolic dysregulation in hepatitis C virus infection

(2018) Keisuke Hino et al.   FREE RADICAL BIOLOGY AND MEDICINE

Impact of 17β-estradiol on complex I kinetics and H2O2 production in liver and skeletal muscle mitochondria

(2018) Maria J. Torres et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Gonadectomy in Mito-Ob mice revealed a sex-dimorphic relationship between prohibitin and sex steroids in adipose tissue biology and glucose homeostasis

(2018) Yang Xin Zi Xu et al.   Biology of Sex Differences

Obesity and gastrointestinal cancer: the interrelationship of adipose and tumour microenvironments

(2018) Jacintha O’Sullivan et al.   Nature Reviews Gastroenterology & Hepatology

Sex Hormones in Acquired Immunity and Autoimmune Disease

(2018) Vaishali R. Moulton   Frontiers in Immunology

Prohibitin – At the crossroads of obesity-linked diabetes and cancer

(2017) Suresh Mishra et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

GPER-1/GPR30 a novel estrogen receptor sited in the cell membrane: therapeutic coupling to breast cancer

(2017) Luis Molina et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Dysregulation of mitochondrial function and biogenesis modulators in adipose tissue of obese children

(2017) R Zamora-Mendoza et al.   INTERNATIONAL JOURNAL OF OBESITY

Estrogen Signaling Contributes to Sex Differences in Macrophage Polarization during Asthma

(2017) Aleksander Keselman et al.   JOURNAL OF IMMUNOLOGY

Sex differences in intracerebral hemorrhage expansion and mortality

(2017) Sandro Marini et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Sex Differences in Treatments, Relative Survival, and Excess Mortality Following Acute Myocardial Infarction: National Cohort Study Using the SWEDEHEART Registry

(2017) Oras A Alabas et al.   Journal of the American Heart Association

Sex and Race Differences in the Association Between Statin Use and the Incidence of Alzheimer Disease

(2017) Julie M. Zissimopoulos et al.   JAMA Neurology

The effects of 17 alpha-estradiol to inhibit inflammation in vitro

(2017) Roberta S. Santos et al.   Biology of Sex Differences

Obesity-related abnormalities couple environmental triggers with genetic susceptibility in adult-onset T1D

(2016) K. Hoa Nguyen et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

A recurring mutation in the respiratory complex 1 protein NDUFB11 is responsible for a novel form of X-linked sideroblastic anemia

(2016) Daniel A. Lichtenstein et al.   BLOOD

17β-estradiol improves hepatic mitochondrial biogenesis and function through PGC1B

(2016) Bel M Galmés-Pascual et al.   JOURNAL OF ENDOCRINOLOGY

Plasma steroid-binding proteins: primary gatekeepers of steroid hormone action

(2016) Geoffrey L Hammond   JOURNAL OF ENDOCRINOLOGY

Expression of a mutant prohibitin from the aP2 gene promoter leads to obesity-linked tumor development in insulin resistance-dependent manner

(2016) S R Ande et al.   ONCOGENE

Prohibitin in Adipose and Immune Functions

(2016) Sudharsana R. Ande et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Prohibitin-induced, obesity-associated insulin resistance and accompanying low-grade inflammation causes NASH and HCC

(2016) Sudharsana R. Ande et al.   Scientific Reports

Evaluating sex as a biological variable in preclinical research: the devil in the details

(2016) Cara Tannenbaum et al.   Biology of Sex Differences

The methyl donor S -adenosylmethionine prevents liver hypoxia and dysregulation of mitochondrial bioenergetic function in a rat model of alcohol-induced fatty liver disease

(2016) Adrienne L. King et al.   Redox Biology

Estrogen receptor alpha and beta in health and disease

(2015) Min Jia et al.   BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM

MitoCarta2.0: an updated inventory of mammalian mitochondrial proteins

(2015) Sarah E. Calvo et al.   NUCLEIC ACIDS RESEARCH

The role of androgens in metabolism, obesity, and diabetes in males and females

(2015) Guadalupe Navarro et al.   Obesity

The evolution of sex differences in disease

(2015) Edward H Morrow   Biology of Sex Differences

Derivation of consensus inactivation status for X-linked genes from genome-wide studies

(2015) Bradley P. Balaton et al.   Biology of Sex Differences

Sex differences in metabolic homeostasis, diabetes, and obesity

(2015) Franck Mauvais-Jarvis   Biology of Sex Differences

Estrogen signaling prevents diet-induced hepatic insulin resistance in male mice with obesity

(2014) Lin Zhu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

How do estrogens control lymphoma?

(2014) Klaus Roemer et al.   BLOOD

Inhibition of lymphoma vascularization and dissemination by estrogen receptor β agonists

(2014) Konstantin Yakimchuk et al.   BLOOD

Prohibitin 1 modulates mitochondrial function of Stat3

(2014) Jie Han et al.   CELLULAR SIGNALLING

Prohibitin Overexpression in Adipocytes Induces Mitochondrial Biogenesis, Leads to Obesity Development, and Affects Glucose Homeostasis in a Sex-Specific Manner

(2014) Sudharsana R. Ande et al.   DIABETES

Androgen Receptor Roles in Insulin Resistance and Obesity in Males: The Linkage of Androgen-Deprivation Therapy to Metabolic Syndrome

(2014) I.-C. Yu et al.   DIABETES

Mitochondrial function/dysfunction in white adipose tissue

(2014) Sihem Boudina et al.   EXPERIMENTAL PHYSIOLOGY

Estrogen Receptor (ER)α-regulated Lipocalin 2 Expression in Adipose Tissue Links Obesity with Breast Cancer Progression

(2014) Brian G. Drew et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Chronic Estradiol Administration In Vivo Promotes the Proinflammatory Response of Macrophages to TLR4 Activation: Involvement of the Phosphatidylinositol 3-Kinase Pathway

(2014) B. Calippe et al.   JOURNAL OF IMMUNOLOGY

Estrogen Signaling in Metabolic Inflammation

(2014) Rosário Monteiro et al.   MEDIATORS OF INFLAMMATION

X chromosome regulation: diverse patterns in development, tissues and disease

(2014) Xinxian Deng et al.   NATURE REVIEWS GENETICS

Modulation of autoimmune rheumatic diseases by oestrogen and progesterone

(2014) Grant C. Hughes et al.   Nature Reviews Rheumatology

Hypothalamic PGC-1α Protects Against High-Fat Diet Exposure by Regulating ERα

(2014) Eugenia Morselli et al.   Cell Reports

Powering the Immune System: Mitochondria in Immune Function and Deficiency

(2014) Melissa A. Walker et al.   Journal of Immunology Research

Potentiation of brain mitochondrial function by S-equol and R/S-equol estrogen receptor β-selective phytoSERM treatments

(2013) Jia Yao et al.   BRAIN RESEARCH

The Role of Estrogens in Control of Energy Balance and Glucose Homeostasis

(2013) Franck Mauvais-Jarvis et al.   ENDOCRINE REVIEWS

Metabolic Pathways in Immune Cell Activation and Quiescence

(2013) Erika L. Pearce et al.   IMMUNITY

MicroRNA-27 (miR-27) Targets Prohibitin and Impairs Adipocyte Differentiation and Mitochondrial Function in Human Adipose-derived Stem Cells

(2013) Ting Kang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Sex Bias in Infectious Disease Epidemiology: Patterns and Processes

(2013) Felipe Guerra-Silveira et al.   PLoS One

Induction of Paclitaxel Resistance by ERα Mediated Prohibitin Mitochondrial-Nuclear Shuttling

(2013) Pei Dong et al.   PLoS One

Systems analysis of sex differences reveals an immunosuppressive role for testosterone in the response to influenza vaccination

(2013) D. Furman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sex Differences in the Gut Microbiome Drive Hormone-Dependent Regulation of Autoimmunity

(2013) J. G. M. Markle et al.   SCIENCE

The Scaffold Protein Prohibitin Is Required for Antigen-Stimulated Signaling in Mast Cells

(2013) D. K. Kim et al.   Science Signaling

SeXX matters in immunity

(2013) J.G. Markle et al.   TRENDS IN IMMUNOLOGY

Personalized vaccinology: One size and dose might not fit both sexes

(2013) Sabra L. Klein et al.   VACCINE

Orchestration of Metabolism by Macrophages

(2012) Subhra K. Biswas et al.   Cell Metabolism

GENCODE: The reference human genome annotation for The ENCODE Project

(2012) J. Harrow et al.   GENOME RESEARCH

Molecular pathogenesis of mantle cell lymphoma

(2012) Pedro Jares et al.   JOURNAL OF CLINICAL INVESTIGATION

Prohibitins and the Cytoplasmic Domain of CD86 Cooperate To Mediate CD86 Signaling in B Lymphocytes

(2012) C. R. Lucas et al.   JOURNAL OF IMMUNOLOGY

MitoNEET-driven alterations in adipocyte mitochondrial activity reveal a crucial adaptive process that preserves insulin sensitivity in obesity

(2012) Christine M Kusminski et al.   NATURE MEDICINE

Retroperitoneal white adipose tissue mitochondrial function and adiponectin expression in response to ovariectomy and 17β-estradiol replacement

(2012) Emilia Amengual-Cladera et al.   STEROIDS

Loss of Prohibitin Membrane Scaffolds Impairs Mitochondrial Architecture and Leads to Tau Hyperphosphorylation and Neurodegeneration

(2012) Carsten Merkwirth et al.   PLoS Genetics

Alternative Macrophage Activation and Metabolism

(2011) Justin I. Odegaard et al.   Annual Review of Pathology-Mechanisms of Disease

The TLR-mediated response of plasmacytoid dendritic cells is positively regulated by estradiol in vivo through cell-intrinsic estrogen receptor   signaling

(2011) C. Seillet et al.   BLOOD

The X chromosome and immune associated genes

(2011) Ilaria Bianchi et al.   JOURNAL OF AUTOIMMUNITY

Androgens and obesity

(2011) Carolyn A Allan et al.   Current Opinion in Endocrinology Diabetes and Obesity

Mitochondrial control of epigenetics

(2010) Robert K. Naviaux   CANCER BIOLOGY & THERAPY

A novel role for mitochondria in regulating epigenetic modifications in the nucleus

(2010) Dominic Smiraglia et al.   CANCER BIOLOGY & THERAPY

Long-term High-fat-diet Feeding Impairs Mitochondrial Biogenesis in Liver of Male and Female Rats

(2010) Antònia Nadal-Casellas et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Epigenetic mechanisms in lupus

(2010) Dipak R Patel et al.   CURRENT OPINION IN RHEUMATOLOGY

The role of prohibitin in cell signaling

(2010) Suresh Mishra et al.   FEBS Journal

Gluteofemoral body fat as a determinant of metabolic health

(2010) K N Manolopoulos et al.   INTERNATIONAL JOURNAL OF OBESITY

Epigenetics and SLE: RFX1 downregulation causes CD11a and CD70 overexpression by altering epigenetic modifications in lupus CD4+ T cells

(2010) Ming Zhao et al.   JOURNAL OF AUTOIMMUNITY

Substrate Fate in Activated Macrophages: A Comparison between Innate, Classic, and Alternative Activation

(2010) J.-C. Rodriguez-Prados et al.   JOURNAL OF IMMUNOLOGY

The Xs and Y of immune responses to viral vaccines

(2010) Sabra L Klein et al.   LANCET INFECTIOUS DISEASES

Dehydroepiandrosterone (DHEA) treatment in vitro inhibits adipogenesis in human omental but not subcutaneous adipose tissue

(2010) S.P.L. Rice et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Promoting the understanding of sex differences to enhance equity and excellence in biomedical science

(2010) Arthur P Arnold   Biology of Sex Differences

Regulation of mitochondrial respiratory chain biogenesis by estrogens/estrogen receptors and physiological, pathological and pharmacological implications

(2009) Jin-Qiang Chen et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Rapid evolution of mammalian X-linked testis microRNAs

(2009) Xuejiang Guo et al.   BMC GENOMICS

Effects of androgens on adipocyte differentiation and adipose tissue explant metabolism in men and women

(2009) Karine Blouin et al.   CLINICAL ENDOCRINOLOGY

Prohibitin Is a Novel Regulator of Antioxidant Response That Attenuates Colonic Inflammation in Mice

(2009) Arianne L. Theiss et al.   GASTROENTEROLOGY

Metabolic Complications of Androgen Deprivation Therapy for Prostate Cancer

(2009) Philip J. Saylor et al.   JOURNAL OF UROLOGY

Identification and Importance of Brown Adipose Tissue in Adult Humans

(2009) Aaron M. Cypess et al.   NEW ENGLAND JOURNAL OF MEDICINE

Gender Dimorphism in High-Fat-Diet-Induced Insulin Resistance in Skeletal Muscle of Aged Rats

(2008) Yolanda Gómez-Pérez et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Human prohibitin 1 maintains the organization and stability of the mitochondrial nucleoids

(2008) Katsumi Kasashima et al.   EXPERIMENTAL CELL RESEARCH

Sex-dependent differences in aged rat brain mitochondrial function and oxidative stress

(2008) Rocío Guevara et al.   FREE RADICAL BIOLOGY AND MEDICINE

A Prescription for Human Immunology

(2008) Mark M. Davis   IMMUNITY

Increased visceral fat and decreased energy expenditure during the menopausal transition

(2008) J C Lovejoy et al.   INTERNATIONAL JOURNAL OF OBESITY

Effects of dihydrotestosterone on differentiation and proliferation of human mesenchymal stem cells and preadipocytes

(2008) Vandana Gupta et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Estradiol Stimulates Transcription of Nuclear Respiratory Factor-1 and Increases Mitochondrial Biogenesis

(2007) Kathleen A. Mattingly et al.   MOLECULAR ENDOCRINOLOGY