Sphingosine 1-phosphate signaling contributes to cardiac inflammation, dysfunction, and remodeling following myocardial infarction

Host endothelial S1PR1 regulation of vascular permeability modulates tumor growth

(2014) Gor Sarkisyan et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

The Development and Maintenance of Paclitaxel-induced Neuropathic Pain Require Activation of the Sphingosine 1-Phosphate Receptor Subtype 1

(2014) Kali Janes et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Elevated sphingosine-1-phosphate promotes sickling and sickle cell disease progression

(2014) Yujin Zhang et al.   JOURNAL OF CLINICAL INVESTIGATION

Adiponectin regulates SR Ca2+ cycling following ischemia/reperfusion via sphingosine 1-phosphate-CaMKII signaling in mice

(2014) Wenjun Yan et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Inflammation and Chronic Heart Failure: From Biomarkers to Novel Anti-inflammatory Therapeutic Strategies

(2014) Georgios Bouras et al.   Medicinal Chemistry

Contributions of cardiomyocyte–cardiac fibroblast–immune cell interactions in heart failure development

(2013) Katsuhito Fujiu et al.   BASIC RESEARCH IN CARDIOLOGY

β 1 -Adrenergic Receptor and Sphingosine-1-Phosphate Receptor 1 (S1PR1) Reciprocal Downregulation Influences Cardiac Hypertrophic Response and Progression to Heart Failure

(2013) Alessandro Cannavo et al.   CIRCULATION

Sphingosine kinase and sphingosine 1-phosphate in the heart: A decade of progress

(2012) Joel S. Karliner   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Sphingosine-1-Phosphate Links Persistent STAT3 Activation, Chronic Intestinal Inflammation, and Development of Colitis-Associated Cancer

(2012) Jie Liang et al.   CANCER CELL

Tumor Necrosis Factor-α–Mediated Downregulation of the Cystic Fibrosis Transmembrane Conductance Regulator Drives Pathological Sphingosine-1-Phosphate Signaling in a Mouse Model of Heart Failure

(2012) Anja Meissner et al.   CIRCULATION

Heart Disease and Stroke Statistics—2013 Update

(2012) Alan S. Go et al.   CIRCULATION

S1P1 inhibits sprouting angiogenesis during vascular development

(2012) A. B. Shoham et al.   DEVELOPMENT

The Sphingosine-1-Phosphate Receptor S1PR1 Restricts Sprouting Angiogenesis by Regulating the Interplay between VE-Cadherin and VEGFR2

(2012) Konstantin Gaengel et al.   DEVELOPMENTAL CELL

Sphingosine-1-phosphate-induced release of TIMP-2 from vascular smooth muscle cells inhibits angiogenesis

(2012) K. S. Mascall et al.   JOURNAL OF CELL SCIENCE

Sphingosine-1-phosphate lyase expression in embryonic and adult murine tissues

(2012) Alexander D. Borowsky et al.   JOURNAL OF LIPID RESEARCH

S1P lyase: a novel therapeutic target for ischemia-reperfusion injury of the heart

(2011) Padmavathi Bandhuvula et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Apelin prevents cardiac fibroblast activation and collagen production through inhibition of sphingosine kinase 1

(2011) Dmitri Pchejetski et al.   EUROPEAN HEART JOURNAL

FTY720 Analogues as Sphingosine Kinase 1 Inhibitors

(2011) Keng G. Lim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Sphingosine-1-phosphate signaling and its role in disease

(2011) Michael Maceyka et al.   TRENDS IN CELL BIOLOGY

A Novel and Efficient Model of Coronary Artery Ligation and Myocardial Infarction in the Mouse

(2010) Erhe Gao et al.   CIRCULATION RESEARCH

STAT3-induced S1PR1 expression is crucial for persistent STAT3 activation in tumors

(2010) Heehyoung Lee et al.   NATURE MEDICINE

Fingolimod (FTY720): discovery and development of an oral drug to treat multiple sclerosis

(2010) Volker Brinkmann et al.   NATURE REVIEWS DRUG DISCOVERY

Sphingolipid signaling and treatment during remodeling of the uninfarcted ventricular wall after myocardial infarction

(2009) Che-Chung Yeh et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Sphingosine-1-phosphate and sphingosine kinase are critical for transforming growth factor- -stimulated collagen production by cardiac fibroblasts

(2009) N. Gellings Lowe et al.   CARDIOVASCULAR RESEARCH

S1P3-mediated cardiac fibrosis in sphingosine kinase 1 transgenic mice involves reactive oxygen species

(2009) Noriko Takuwa et al.   CARDIOVASCULAR RESEARCH

Sphingosine-1-phosphate signaling and biological activities in the cardiovascular system

(2008) Y TAKUWA   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS