标题
Helper T cell differentiation
作者
关键词
-
出版物
Cellular & Molecular Immunology
Volume -, Issue -, Pages -
出版商
Springer Nature
发表日期
2019-03-14
DOI
10.1038/s41423-019-0220-6
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Defining T Cell States Associated with Response to Checkpoint Immunotherapy in Melanoma
- (2019) Moshe Sade-Feldman et al. CELL
- Genome-wide CRISPR Screens in T Helper Cells Reveal Pervasive Crosstalk between Activation and Differentiation
- (2019) Johan Henriksson et al. CELL
- Mitochondrial complex III is essential for suppressive function of regulatory T cells
- (2019) Samuel E. Weinberg et al. NATURE
- Rebooting Human Immunology
- (2018) Mark M. Davis et al. Annual Review of Immunology
- Unraveling the Complex Interplay Between T Cell Metabolism and Function
- (2018) Ramon I. Klein Geltink et al. Annual Review of Immunology
- Non-classical Immunity Controls Microbiota Impact on Skin Immunity and Tissue Repair
- (2018) Jonathan L. Linehan et al. CELL
- TCR Transgenic Mice Reveal Stepwise, Multi-site Acquisition of the Distinctive Fat-Treg Phenotype
- (2018) Chaoran Li et al. CELL
- Etomoxir Actions on Regulatory and Memory T Cells Are Independent of Cpt1a-Mediated Fatty Acid Oxidation
- (2018) Brenda Raud et al. Cell Metabolism
- CD150 high Bone Marrow Tregs Maintain Hematopoietic Stem Cell Quiescence and Immune Privilege via Adenosine
- (2018) Yuichi Hirata et al. Cell Stem Cell
- Extrathymically Generated Regulatory T Cells Establish a Niche for Intestinal Border-Dwelling Bacteria and Affect Physiologic Metabolite Balance
- (2018) Clarissa Campbell et al. IMMUNITY
- Regulatory T cells in autoimmune disease
- (2018) Margarita Dominguez-Villar et al. NATURE IMMUNOLOGY
- c-Maf controls immune responses by regulating disease-specific gene networks and repressing IL-2 in CD4+ T cells
- (2018) Leona Gabryšová et al. NATURE IMMUNOLOGY
- Tissue-resident memory T cells at the center of immunity to solid tumors
- (2018) Derk Amsen et al. NATURE IMMUNOLOGY
- Single-cell gene expression reveals a landscape of regulatory T cell phenotypes shaped by the TCR
- (2018) David Zemmour et al. NATURE IMMUNOLOGY
- mTOR coordinates transcriptional programs and mitochondrial metabolism of activated Treg subsets to protect tissue homeostasis
- (2018) Nicole M. Chapman et al. Nature Communications
- Hallmarks of T-cell Exit from Quiescence
- (2018) Nicole M. Chapman et al. Cancer Immunology Research
- Differential IL-2 expression defines developmental fates of follicular versus nonfollicular helper T cells
- (2018) Daniel DiToro et al. SCIENCE
- Distinct Regulation of Th17 and Th1 Cell Differentiation by Glutaminase-Dependent Metabolism
- (2018) Marc O. Johnson et al. CELL
- T Helper Cell Cytokines Modulate Intestinal Stem Cell Renewal and Differentiation
- (2018) Moshe Biton et al. CELL
- Metabolic heterogeneity underlies reciprocal fates of TH17 cell stemness and plasticity
- (2018) Peer W. F. Karmaus et al. NATURE
- Commensal-specific T cell plasticity promotes rapid tissue adaptation to injury
- (2018) Oliver J. Harrison et al. SCIENCE
- Store-Operated Ca 2+ Entry Controls Clonal Expansion of T Cells through Metabolic Reprogramming
- (2017) Martin Vaeth et al. IMMUNITY
- Regulatory T Cell Migration Is Dependent on Glucokinase-Mediated Glycolysis
- (2017) Madhav Kishore et al. IMMUNITY
- CCCTC-Binding Factor Translates Interleukin 2- and α-Ketoglutarate-Sensitive Metabolic Changes in T Cells into Context-Dependent Gene Programs
- (2017) Danielle A. Chisolm et al. IMMUNITY
- Integrative Proteomics and Phosphoproteomics Profiling Reveals Dynamic Signaling Networks and Bioenergetics Pathways Underlying T Cell Activation
- (2017) Haiyan Tan et al. IMMUNITY
- Cutting Edge: c-Maf Is Required for Regulatory T Cells To Adopt RORγt+and Follicular Phenotypes
- (2017) Joshua D. Wheaton et al. JOURNAL OF IMMUNOLOGY
- Stability and function of regulatory T cells expressing the transcription factor T-bet
- (2017) Andrew G. Levine et al. NATURE
- Homeostatic control of metabolic and functional fitness of Treg cells by LKB1 signalling
- (2017) Kai Yang et al. NATURE
- Scaling single-cell genomics from phenomenology to mechanism
- (2017) Amos Tanay et al. NATURE
- Heterogeneity of Human CD4+T Cells Against Microbes
- (2016) Federica Sallusto Annual Review of Immunology
- Oxygen Sensing by T Cells Establishes an Immunologically Tolerant Metastatic Niche
- (2016) David Clever et al. CELL
- Constitutive Glycolytic Metabolism Supports CD8 + T Cell Effector Memory Differentiation during Viral Infection
- (2016) Anthony T. Phan et al. IMMUNITY
- mTORC1 and mTORC2 Kinase Signaling and Glucose Metabolism Drive Follicular Helper T Cell Differentiation
- (2016) Hu Zeng et al. IMMUNITY
- Phosphoproteomic Analyses of Interleukin 2 Signaling Reveal Integrated JAK Kinase-Dependent and -Independent Networks in CD8 + T Cells
- (2016) Sarah H. Ross et al. IMMUNITY
- Follicular CXCR5-expressing CD8+ T cells curtail chronic viral infection
- (2016) Ran He et al. NATURE
- Defining CD8+ T cells that provide the proliferative burst after PD-1 therapy
- (2016) Se Jin Im et al. NATURE
- Autophagy enforces functional integrity of regulatory T cells by coupling environmental cues and metabolic homeostasis
- (2016) Jun Wei et al. NATURE IMMUNOLOGY
- TFH cells progressively differentiate to regulate the germinal center response
- (2016) Jason S Weinstein et al. NATURE IMMUNOLOGY
- Foxp3 and Toll-like receptor signaling balance Treg cell anabolic metabolism for suppression
- (2016) Valerie A Gerriets et al. NATURE IMMUNOLOGY
- Glucose and glutamine fuel protein O-GlcNAcylation to control T cell self-renewal and malignancy
- (2016) Mahima Swamy et al. NATURE IMMUNOLOGY
- CXCR5+ follicular cytotoxic T cells control viral infection in B cell follicles
- (2016) Yew Ann Leong et al. NATURE IMMUNOLOGY
- Aerobic glycolysis promotes T helper 1 cell differentiation through an epigenetic mechanism
- (2016) M. Peng et al. SCIENCE
- Single-Cell Genomics Unveils Critical Regulators of Th17 Cell Pathogenicity
- (2015) Jellert T. Gaublomme et al. CELL
- CD5L/AIM Regulates Lipid Biosynthesis and Restrains Th17 Cell Pathogenicity
- (2015) Chao Wang et al. CELL
- Phosphoenolpyruvate Is a Metabolic Checkpoint of Anti-tumor T Cell Responses
- (2015) Ping-Chih Ho et al. CELL
- Type 1 regulatory T cells: a new mechanism of peripheral immune tolerance
- (2015) Hanyu Zeng et al. Cellular & Molecular Immunology
- Regulation of human helper T cell subset differentiation by cytokines
- (2015) Nathalie Schmitt et al. CURRENT OPINION IN IMMUNOLOGY
- A Wave of Regulatory T Cells into Neonatal Skin Mediates Tolerance to Commensal Microbes
- (2015) Tiffany C. Scharschmidt et al. IMMUNITY
- MyD88 Adaptor-Dependent Microbial Sensing by Regulatory T Cells Promotes Mucosal Tolerance and Enforces Commensalism
- (2015) Sen Wang et al. IMMUNITY
- The Energy Sensor AMPK Regulates T Cell Metabolic Adaptation and Effector Responses In Vivo
- (2015) Julianna Blagih et al. IMMUNITY
- The Interleukin-2-mTORc1 Kinase Axis Defines the Signaling, Differentiation, and Metabolism of T Helper 1 and Follicular B Helper T Cells
- (2015) John P. Ray et al. IMMUNITY
- Th17 Cell Pathway in Human Immunity: Lessons from Genetics and Therapeutic Interventions
- (2015) Dhavalkumar D. Patel et al. IMMUNITY
- Regulatory T Cell Reprogramming toward a Th2-Cell-like Lineage Impairs Oral Tolerance and Promotes Food Allergy
- (2015) Magali Noval Rivas et al. IMMUNITY
- Commensal–dendritic-cell interaction specifies a unique protective skin immune signature
- (2015) Shruti Naik et al. NATURE
- Th17 cells transdifferentiate into regulatory T cells during resolution of inflammation
- (2015) Nicola Gagliani et al. NATURE
- Treg cells require the phosphatase PTEN to restrain TH1 and TFH cell responses
- (2015) Sharad Shrestha et al. NATURE IMMUNOLOGY
- The transcription factor TCF-1 initiates the differentiation of TFH cells during acute viral infection
- (2015) Lifan Xu et al. NATURE IMMUNOLOGY
- Control of PI(3) kinase in Treg cells maintains homeostasis and lineage stability
- (2015) Alexandria Huynh et al. NATURE IMMUNOLOGY
- LEF-1 and TCF-1 orchestrate TFH differentiation by regulating differentiation circuits upstream of the transcriptional repressor Bcl6
- (2015) Youn Soo Choi et al. NATURE IMMUNOLOGY
- Th17 cells give rise to Th1 cells that are required for the pathogenesis of colitis
- (2015) Stacey N. Harbour et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The microbiota regulates type 2 immunity through ROR t+ T cells
- (2015) C. Ohnmacht et al. SCIENCE
- Individual intestinal symbionts induce a distinct population of ROR + regulatory T cells
- (2015) E. Sefik et al. SCIENCE
- Obesity Drives Th17 Cell Differentiation by Inducing the Lipid Metabolic Kinase, ACC1
- (2015) Yusuke Endo et al. Cell Reports
- Control of the Inheritance of Regulatory T Cell Identity by a cis Element in the Foxp3 Locus
- (2014) Yongqiang Feng et al. CELL
- Inflammatory T Cell Responses Rely on Amino Acid Transporter ASCT2 Facilitation of Glutamine Uptake and mTORC1 Kinase Activation
- (2014) Mako Nakaya et al. IMMUNITY
- Foxp3+ T Cells Regulate Immunoglobulin A Selection and Facilitate Diversification of Bacterial Species Responsible for Immune Homeostasis
- (2014) Shimpei Kawamoto et al. IMMUNITY
- Metabolic programming and PDHK1 control CD4+ T cell subsets and inflammation
- (2014) Valerie A. Gerriets et al. JOURNAL OF CLINICAL INVESTIGATION
- The alarmin IL-33 promotes regulatory T-cell function in the intestine
- (2014) Chris Schiering et al. NATURE
- Transcription factor achaete-scute homologue 2 initiates follicular T-helper-cell development
- (2014) Xindong Liu et al. NATURE
- Dynamic expression of transcription factors T-bet and GATA-3 by regulatory T cells maintains immunotolerance
- (2014) Fang Yu et al. NATURE IMMUNOLOGY
- De novo fatty acid synthesis controls the fate between regulatory T and T helper 17 cells
- (2014) Luciana Berod et al. NATURE MEDICINE
- Posttranscriptional Control of T Cell Effector Function by Aerobic Glycolysis
- (2013) Chih-Hao Chang et al. CELL
- T Cell Exit from Quiescence and Differentiation into Th2 Cells Depend on Raptor-mTORC1-Mediated Metabolic Reprogramming
- (2013) Kai Yang et al. IMMUNITY
- The Th17 family: flexibility follows function
- (2013) Rajatava Basu et al. IMMUNOLOGICAL REVIEWS
- Dynamic regulatory network controlling TH17 cell differentiation
- (2013) Nir Yosef et al. NATURE
- mTORC1 couples immune signals and metabolic programming to establish Treg-cell function
- (2013) Hu Zeng et al. NATURE
- Hypoxia-inducible factors enhance the effector responses of CD8+ T cells to persistent antigen
- (2013) Andrew L Doedens et al. NATURE IMMUNOLOGY
- Plasticity of TH17 cells in Peyer's patches is responsible for the induction of T cell–dependent IgA responses
- (2013) Keiji Hirota et al. NATURE IMMUNOLOGY
- Control of amino-acid transport by antigen receptors coordinates the metabolic reprogramming essential for T cell differentiation
- (2013) Linda V Sinclair et al. NATURE IMMUNOLOGY
- Pathogenic conversion of Foxp3+ T cells into TH17 cells in autoimmune arthritis
- (2013) Noriko Komatsu et al. NATURE MEDICINE
- A Validated Regulatory Network for Th17 Cell Specification
- (2012) Maria Ciofani et al. CELL
- T-bet+ Treg Cells Undergo Abortive Th1 Cell Differentiation due to Impaired Expression of IL-12 Receptor β2
- (2012) Meghan A. Koch et al. IMMUNITY
- STAT5 is a potent negative regulator of TFHcell differentiation
- (2012) Robert J. Johnston et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Extrathymically generated regulatory T cells control mucosal TH2 inflammation
- (2012) Steven Z. Josefowicz et al. NATURE
- Pathogen-induced human TH17 cells produce IFN-γ or IL-10 and are regulated by IL-1β
- (2012) Christina E. Zielinski et al. NATURE
- Transcription factor Foxp3 and its protein partners form a complex regulatory network
- (2012) Dipayan Rudra et al. NATURE IMMUNOLOGY
- Transcription factor IRF4 determines germinal center formation through follicular T-helper cell differentiation
- (2012) N. Bollig et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Control of TH17/Treg Balance by Hypoxia-Inducible Factor 1
- (2011) Eric V. Dang et al. CELL
- The Transcription Factor Myc Controls Metabolic Reprogramming upon T Lymphocyte Activation
- (2011) Ruoning Wang et al. IMMUNITY
- Th17 Cells Are Long Lived and Retain a Stem Cell-like Molecular Signature
- (2011) Pawel Muranski et al. IMMUNITY
- Functional and Epigenetic Studies Reveal Multistep Differentiation and Plasticity of In Vitro-Generated and In Vivo-Derived Follicular T Helper Cells
- (2011) Kristina T. Lu et al. IMMUNITY
- An Essential Role of the Transcription Factor GATA-3 for the Function of Regulatory T Cells
- (2011) Yunqi Wang et al. IMMUNITY
- GATA3 controls Foxp3+ regulatory T cell fate during inflammation in mice
- (2011) Elizabeth A. Wohlfert et al. JOURNAL OF CLINICAL INVESTIGATION
- HIF1α–dependent glycolytic pathway orchestrates a metabolic checkpoint for the differentiation of TH17 and Tregcells
- (2011) Lewis Z. Shi et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Rapid In Vivo Conversion of Effector T Cells into Th2 Cells during Helminth Infection
- (2011) M. Panzer et al. JOURNAL OF IMMUNOLOGY
- Plasticity of Human Regulatory T Cells in Healthy Subjects and Patients with Type 1 Diabetes
- (2011) Stephanie A. McClymont et al. JOURNAL OF IMMUNOLOGY
- Regulation of the Germinal Center Reaction by Foxp3+ Follicular Regulatory T Cells
- (2011) I. Wollenberg et al. JOURNAL OF IMMUNOLOGY
- Cutting Edge: Distinct Glycolytic and Lipid Oxidative Metabolic Programs Are Essential for Effector and Regulatory CD4+ T Cell Subsets
- (2011) R. D. Michalek et al. JOURNAL OF IMMUNOLOGY
- Transcription factor c-Maf mediates the TGF-β-dependent suppression of IL-22 production in TH17 cells
- (2011) Sascha Rutz et al. NATURE IMMUNOLOGY
- An IL-9 fate reporter demonstrates the induction of an innate IL-9 response in lung inflammation
- (2011) Christoph Wilhelm et al. NATURE IMMUNOLOGY
- Fate mapping of IL-17-producing T cells in inflammatory responses
- (2011) Keiji Hirota et al. NATURE IMMUNOLOGY
- The kinase mTOR regulates the differentiation of helper T cells through the selective activation of signaling by mTORC1 and mTORC2
- (2011) Greg M Delgoffe et al. NATURE IMMUNOLOGY
- Follicular regulatory T cells expressing Foxp3 and Bcl-6 suppress germinal center reactions
- (2011) Yeonseok Chung et al. NATURE MEDICINE
- Identification of T helper type 1–like, Foxp3+ regulatory T cells in human autoimmune disease
- (2011) Margarita Dominguez-Villar et al. NATURE MEDICINE
- Foxp3+ follicular regulatory T cells control the germinal center response
- (2011) Michelle A Linterman et al. NATURE MEDICINE
- Mammalian Target of Rapamycin Protein Complex 2 Regulates Differentiation of Th1 and Th2 Cell Subsets via Distinct Signaling Pathways
- (2010) Keunwook Lee et al. IMMUNITY
- Interferons Direct Th2 Cell Reprogramming to Generate a Stable GATA-3+T-bet+ Cell Subset with Combined Th2 and Th1 Cell Functions
- (2010) Ahmed N. Hegazy et al. IMMUNITY
- Epigenetic Instability of Cytokine and Transcription Factor Gene Loci Underlies Plasticity of the T Helper 17 Cell Lineage
- (2010) Ryuta Mukasa et al. IMMUNITY
- Role of conserved non-coding DNA elements in the Foxp3 gene in regulatory T-cell fate
- (2010) Ye Zheng et al. NATURE
- Generation of pathogenic TH17 cells in the absence of TGF-β signalling
- (2010) Kamran Ghoreschi et al. NATURE
- Global Mapping of H3K4me3 and H3K27me3 Reveals Specificity and Plasticity in Lineage Fate Determination of Differentiating CD4+ T Cells
- (2009) Gang Wei et al. IMMUNITY
- The Transcriptional Repressor Bcl-6 Directs T Follicular Helper Cell Lineage Commitment
- (2009) Di Yu et al. IMMUNITY
- Indispensable Role of the Runx1-Cbfβ Transcription Complex for In Vivo-Suppressive Function of FoxP3+ Regulatory T Cells
- (2009) Akihiko Kitoh et al. IMMUNITY
- Critical Regulation of Early Th17 Cell Differentiation by Interleukin-1 Signaling
- (2009) Yeonseok Chung et al. IMMUNITY
- The mTOR Kinase Differentially Regulates Effector and Regulatory T Cell Lineage Commitment
- (2009) Greg M. Delgoffe et al. IMMUNITY
- Late Developmental Plasticity in the T Helper 17 Lineage
- (2009) Yun Kyung Lee et al. IMMUNITY
- Highly purified Th17 cells from BDC2.5NOD mice convert into Th1-like cells in NOD/SCID recipient mice
- (2009) David Bending et al. JOURNAL OF CLINICAL INVESTIGATION
- Th1, Th17, and Th9 Effector Cells Induce Experimental Autoimmune Encephalomyelitis with Different Pathological Phenotypes
- (2009) A. Jager et al. JOURNAL OF IMMUNOLOGY
- c-Maf Regulates IL-10 Expression during Th17 Polarization
- (2009) Jiangnan Xu et al. JOURNAL OF IMMUNOLOGY
- Regulatory T-cell suppressor program co-opts transcription factor IRF4 to control TH2 responses
- (2009) Ye Zheng et al. NATURE
- The interleukin 23 receptor is essential for the terminal differentiation of interleukin 17–producing effector T helper cells in vivo
- (2009) Mandy J McGeachy et al. NATURE IMMUNOLOGY
- Runx-CBFβ complexes control expression of the transcription factor Foxp3 in regulatory T cells
- (2009) Dipayan Rudra et al. NATURE IMMUNOLOGY
- Identification of a human helper T cell population that has abundant production of interleukin 22 and is distinct from TH-17, TH1 and TH2 cells
- (2009) Sara Trifari et al. NATURE IMMUNOLOGY
- Cytokine-secreting follicular T cells shape the antibody repertoire
- (2009) R Lee Reinhardt et al. NATURE IMMUNOLOGY
- Production of interleukin 22 but not interleukin 17 by a subset of human skin-homing memory T cells
- (2009) Thomas Duhen et al. NATURE IMMUNOLOGY
- The transcription factor T-bet controls regulatory T cell homeostasis and function during type 1 inflammation
- (2009) Meghan A Koch et al. NATURE IMMUNOLOGY
- Preferential Generation of Follicular B Helper T Cells from Foxp3+ T Cells in Gut Peyer's Patches
- (2009) M. Tsuji et al. SCIENCE
- Bcl6 and Blimp-1 Are Reciprocal and Antagonistic Regulators of T Follicular Helper Cell Differentiation
- (2009) R. J. Johnston et al. SCIENCE
- Bcl6 Mediates the Development of T Follicular Helper Cells
- (2009) R. I. Nurieva et al. SCIENCE
- CD4+ Regulatory T Cells Control TH17 Responses in a Stat3-Dependent Manner
- (2009) A. Chaudhry et al. SCIENCE
- Generation of T Follicular Helper Cells Is Mediated by Interleukin-21 but Independent of T Helper 1, 2, or 17 Cell Lineages
- (2008) Roza I. Nurieva et al. IMMUNITY
- T Helper 17 Lineage Differentiation Is Programmed by Orphan Nuclear Receptors RORα and RORγ
- (2008) Xuexian O. Yang et al. IMMUNITY
- Long-lived virus-reactive memory T cells generated from purified cytokine-secreting T helper type 1 and type 2 effectors
- (2008) Max Löhning et al. JOURNAL OF EXPERIMENTAL MEDICINE
- TGF-β-induced Foxp3 inhibits TH17 cell differentiation by antagonizing RORγt function
- (2008) Liang Zhou et al. NATURE
- Interactions among the transcription factors Runx1, RORγt and Foxp3 regulate the differentiation of interleukin 17–producing T cells
- (2008) Fuping Zhang et al. NATURE IMMUNOLOGY
- Transforming growth factor-β 'reprograms' the differentiation of T helper 2 cells and promotes an interleukin 9–producing subset
- (2008) Marc Veldhoen et al. NATURE IMMUNOLOGY
- The costimulatory molecule ICOS regulates the expression of c-Maf and IL-21 in the development of follicular T helper cells and TH-17 cells
- (2008) Aurelie T Bauquet et al. NATURE IMMUNOLOGY
- IL-4 inhibits TGF-β-induced Foxp3+ T cells and, together with TGF-β, generates IL-9+ IL-10+ Foxp3− effector T cells
- (2008) Valérie Dardalhon et al. NATURE IMMUNOLOGY
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started