Ossified blood vessels in primary familial brain calcification elicit a neurotoxic astrocyte response

Mice Knocked Out for the Primary Brain Calcification–Associated Gene Slc20a2 Show Unimpaired Prenatal Survival but Retarded Growth and Nodules in the Brain that Grow and Calcify Over Time

(2018) Nina Jensen et al.   AMERICAN JOURNAL OF PATHOLOGY

Neural circuit dysfunction in mouse models of neurodevelopmental disorders

(2018) Isabel del Pino et al.   CURRENT OPINION IN NEUROBIOLOGY

Biallelic Mutations in MYORG Cause Autosomal Recessive Primary Familial Brain Calcification

(2018) Xiang-Ping Yao et al.   NEURON

Serum Fetuin-A Levels in Patients with Bilateral Basal Ganglia Calcification

(2018) Bekir Enes Demiryurek et al.   NEUROSCIENCE LETTERS

Normal aging induces A1-like astrocyte reactivity

(2018) Laura E. Clarke et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular Architecture of the Mouse Nervous System

(2018) Amit Zeisel et al.   CELL

A molecular atlas of cell types and zonation in the brain vasculature

(2018) Michael Vanlandewijck et al.   NATURE

Primary familial brain calcification with a novel SLC20A2 mutation: Analysis of PiT-2 expression and localization

(2017) Ilaria Taglia et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Neurotoxic reactive astrocytes are induced by activated microglia

(2017) Shane A. Liddelow et al.   NATURE

Inherited Arterial Calcification Syndromes: Etiologies and Treatment Concepts

(2017) Yvonne Nitschke et al.   Current Osteoporosis Reports

Clinical and radiological diversity in genetically confirmed primary familial brain calcification

(2017) Shingo Koyama et al.   Scientific Reports

Reactive gliosis in the pathogenesis of CNS diseases

(2016) Milos Pekny et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

SLC20A2 Deficiency in Mice Leads to Elevated Phosphate Levels in Cerbrospinal Fluid and Glymphatic Pathway-Associated Arteriolar Calcification, and Recapitulates Human Idiopathic Basal Ganglia Calcification

(2016) Mary Catherine Wallingford et al.   BRAIN PATHOLOGY

New perspectives on rare connective tissue calcifying diseases

(2016) Nabil A Rashdan et al.   CURRENT OPINION IN PHARMACOLOGY

Primary Brain Calcification Causal PiT2 Transport-Knockout Variants can Exert Dominant Negative Effects on Wild-Type PiT2 Transport Function in Mammalian Cells

(2016) Frederik Tibert Larsen et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Transgenerational transmission and modification of pathological traits induced by prenatal immune activation

(2016) U Weber-Stadlbauer et al.   MOLECULAR PSYCHIATRY

High-throughput discovery of novel developmental phenotypes

(2016) Mary E. Dickinson et al.   NATURE

Type I interferonopathies in pediatric rheumatology

(2016) Stefano Volpi et al.   Pediatric Rheumatology

Genetics and molecular biology of brain calcification

(2015) Hao Deng et al.   AGEING RESEARCH REVIEWS

The dark and bright side of atherosclerotic calcification

(2015) Giuseppe Pugliese et al.   ATHEROSCLEROSIS

Fluorescent Bisphosphonate and Carboxyphosphonate Probes: A Versatile Imaging Toolkit for Applications in Bone Biology and Biomedicine

(2015) Shuting Sun et al.   BIOCONJUGATE CHEMISTRY

Podoplanin

(2015) Kushal Kolar et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Mutations in XPR1 cause primary familial brain calcification associated with altered phosphate export

(2015) Andrea Legati et al.   NATURE GENETICS

Familial idiopathic basal ganglia calcification: Histopathologic features of an autopsied patient with anSLC20A2mutation

(2015) Tadashi Kimura et al.   NEUROPATHOLOGY

Vascular calcification: Mechanisms of vascular smooth muscle cell calcification

(2015) Jane A. Leopold   TRENDS IN CARDIOVASCULAR MEDICINE

Relationships among Parvalbumin-Immunoreactive Neuron Density, Phase-Locked Gamma Oscillations, and Autistic/Schizophrenic Symptoms in PDGFR-β Knock-Out and Control Mice

(2015) Tomoya Nakamura et al.   PLoS One

Lipocalin (LCN) 2 Mediates Pro-Atherosclerotic Processes and Is Elevated in Patients with Coronary Artery Disease

(2015) Raghav Oberoi et al.   PLoS One

Functional Characterization of Germline Mutations in PDGFB and PDGFRB in Primary Familial Brain Calcification

(2015) Michael Vanlandewijck et al.   PLoS One

PDGF, Pericytes and the Pathogenesis of Idiopathic Basal Ganglia Calcification (IBGC)

(2014) Christer Betsholtz et al.   BRAIN PATHOLOGY

Patterns and pathways of calcification in the developing brain

(2014) Emily McCartney et al.   DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY

Zebrafish enpp1 mutants exhibit pathological mineralization, mimicking features of generalized arterial calcification of infancy (GACI) and pseudoxanthoma elasticum (PXE)

(2014) A. Apschner et al.   Disease Models & Mechanisms

Genetic Screening and Functional Characterization ofPDGFRBMutations Associated with Basal Ganglia Calcification of Unknown Etiology

(2014) Monica Sanchez-Contreras et al.   HUMAN MUTATION

Idiopathic basal ganglia calcification-associatedPDGFRBmutations impair the receptor signalling

(2014) Florence A. Arts et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Perturbation of specific pro-mineralizing signalling pathways in human and murine pseudoxanthoma elasticum

(2014) Mohammad J Hosen et al.   Orphanet Journal of Rare Diseases

Phenotypic spectrum of probable and genetically-confirmed idiopathic basal ganglia calcification

(2013) Gaël Nicolas et al.   BRAIN

Localization of type-III sodium-dependent phosphate transporter 2 in the mouse brain

(2013) Masatoshi Inden et al.   BRAIN RESEARCH

Defective Extracellular Pyrophosphate Metabolism Promotes Vascular Calcification in a Mouse Model of Hutchinson-Gilford Progeria Syndrome That Is Ameliorated on Pyrophosphate Treatment

(2013) Ricardo Villa-Bellosta et al.   CIRCULATION

A Japanese family with idiopathic basal ganglia calcification with novel SLC20A2 mutation presenting with late-onset hallucination and delusion

(2013) Kensaku Kasuga et al.   JOURNAL OF NEUROLOGY

Structural and molecular interrogation of intact biological systems

(2013) Kwanghun Chung et al.   NATURE

Mutations in the gene encoding PDGF-B cause brain calcifications in humans and mice

(2013) Annika Keller et al.   NATURE GENETICS

SLC20A2 and THAP1 deletion in familial basal ganglia calcification with dystonia

(2013) Matt Baker et al.   NEUROGENETICS

Reactive astrocytes secrete lcn2 to promote neuron death

(2013) F. Bi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nanoparticle-Based Test Measures Overall Propensity for Calcification in Serum

(2012) A. Pasch et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Mutations in SLC20A2 link familial idiopathic basal ganglia calcification with phosphate homeostasis

(2012) Cheng Wang et al.   NATURE GENETICS

A delivery system targeting bone formation surfaces to facilitate RNAi-based anabolic therapy

(2012) Ge Zhang et al.   NATURE MEDICINE

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

Mutation of the PDGFRB gene as a cause of idiopathic basal ganglia calcification

(2012) G. Nicolas et al.   NEUROLOGY

Mechanisms and Clinical Consequences of Vascular Calcification

(2012) Dongxing Zhu et al.   Frontiers in Endocrinology

Biomineralization of bone: a fresh view of the roles of non-collagenous proteins

(2011) Jeffrey Paul Gorski   Frontiers in Bioscience-Landmark

The Roles of Cerebral Blood Flow, Capillary Transit Time Heterogeneity, and Oxygen Tension in Brain Oxygenation and Metabolism

(2011) Sune N Jespersen et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Detection of Cerebral Microbleeds with Quantitative Susceptibility Mapping in the Arcabeta Mouse Model of Cerebral Amyloidosis

(2011) Jan Klohs et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Cognitive and Socio-Emotional Deficits in Platelet-Derived Growth Factor Receptor-β Gene Knockout Mice

(2011) Phuong Thi Hong Nguyen et al.   PLoS One

Basal ganglia calcification on computer tomographic scan

(2010) K. Puvanendran et al.   ACTA NEUROLOGICA SCANDINAVICA

The amazing osteocyte

(2010) Lynda F Bonewald   JOURNAL OF BONE AND MINERAL RESEARCH

Dopamine Transporter SPECT/CT and Perfusion Brain SPECT Imaging in Idiopathic Basal Ganglia Calcinosis

(2009) Anna Paschali et al.   CLINICAL NUCLEAR MEDICINE

Familial idiopathic basal ganglia calcification: a challenging clinical–pathological correlation

(2009) Christian Wider et al.   JOURNAL OF NEUROLOGY

CADASIL

(2009) Hugues Chabriat et al.   LANCET NEUROLOGY

Bisphosphonates in Chronic Kidney Disease; Balancing Potential Benefits and Adverse Effects on Bone and Soft Tissue

(2008) N. D. Toussaint et al.   Clinical Journal of the American Society of Nephrology