The biological characteristics of transcription factors AP-2α and AP-2γ and their importance in various types of cancers

Long non-coding RNA CCAL promotes hepatocellular carcinoma progression by regulating AP-2α and Wnt/β-catenin pathway

(2018) Yu Liu et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

miR-25-3p, Positively Regulated by Transcription Factor AP-2α, Regulates the Metabolism of C2C12 Cells by Targeting Akt1

(2018) Feng Zhang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

MiR-10a-5p targets TFAP2C to promote gemcitabine resistance in pancreatic ductal adenocarcinoma

(2018) Guangbing Xiong et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

TFAP2C regulates transcription in human naive pluripotency by opening enhancers

(2018) William A. Pastor et al.   NATURE CELL BIOLOGY

Identification of the key transcription factors in esophageal squamous cell carcinoma

(2018) Yuefeng Zhang et al.   Journal of Thoracic Disease

LncRNA UCA1, Upregulated in CRC Biopsies and Downregulated in Serum Exosomes, Controls mRNA Expression by RNA-RNA Interactions

(2018) Cristina Barbagallo et al.   Molecular Therapy-Nucleic Acids

LncRNA GAS5 Indel Genetic Polymorphism Contributes to Glioma Risk Through Interfering Binding of Transcriptional Factor TFAP2A

(2018) Jupeng Yuan et al.   DNA AND CELL BIOLOGY

MiR-1254 suppresses HO-1 expression through seed region-dependent silencing and non-seed interaction with TFAP2A transcript to attenuate NSCLC growth

(2017) Mengfan Pu et al.   PLoS Genetics

Distinct Activities of Tfap2A and Tfap2B in the Specification of GABAergic Interneurons in the Developing Cerebellum

(2017) Norliyana Zainolabidin et al.   Frontiers in Molecular Neuroscience

MicroRNA-1304 suppresses human non-small cell lung cancer cell growth in vitro by targeting heme oxygenase-1

(2016) Cheng-gang Li et al.   ACTA PHARMACOLOGICA SINICA

Feature-based classification of human transcription factors into hypothetical sub-classes related to regulatory function

(2016) Rezvan Ehsani et al.   BMC BIOINFORMATICS

Altered long non-coding RNA transcriptomic profiles in brain microvascular endothelium after cerebral ischemia

(2016) J. Zhang et al.   EXPERIMENTAL NEUROLOGY

AP-2α inhibits hepatocellular carcinoma cell growth and migration

(2016) WENHUAN HUANG et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

EGFR Is Regulated by TFAP2C in Luminal Breast Cancer and Is a Target for Vandetanib

(2016) J. P. De Andrade et al.   MOLECULAR CANCER THERAPEUTICS

LncPRESS1 Is a p53-Regulated LncRNA that Safeguards Pluripotency by Disrupting SIRT6-Mediated De-acetylation of Histone H3K56

(2016) Abhinav K. Jain et al.   MOLECULAR CELL

TFAP2C promotes lung tumorigenesis and aggressiveness through miR-183- and miR-33a-mediated cell cycle regulation

(2016) J Kang et al.   ONCOGENE

Carcinogenesis explained within the context of a theory of organisms

(2016) Carlos Sonnenschein et al.   PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY

MiR-193a-5p Targets the Coding Region of AP-2α mRNA and Induces Cisplatin Resistance in Bladder Cancers

(2016) Ji Zhou et al.   Journal of Cancer

A comparison of the transcriptome of Drosophila melanogaster in response to entomopathogenic fungus, ionizing radiation, starvation and cold shock

(2015) Alexey Moskalev et al.   BMC GENOMICS

Selective inhibition of esophageal cancer cells by combination of HDAC inhibitors and Azacytidine

(2015) Theresa D Ahrens et al.   Epigenetics

Theories of cancer origin

(2015) Roman Paduch   EUROPEAN JOURNAL OF CANCER PREVENTION

Long non-coding RNA CCAL regulates colorectal cancer progression by activating Wnt/β-catenin signalling pathway via suppression of activator protein 2α

(2015) Yanlei Ma et al.   GUT

The role of Tcfap2c in tumorigenesis and cancer growth in an activated Neu model of mammary carcinogenesis

(2015) J M Park et al.   ONCOGENE

miR-638 promotes melanoma metastasis and protects melanoma cells from apoptosis and autophagy

(2015) Animesh Bhattacharya et al.   Oncotarget

Aberrant CpG methylation of theTFAP2Agene constitutes a mechanism for loss ofTFAP2Aexpression in human metastatic melanoma

(2015) Andrea R Hallberg et al.   Epigenetics

Expression of AP-2γ in placentas of patients with preeclampsia and of smokers

(2014) Hannah A. Schneider et al.   ARCHIVES OF GYNECOLOGY AND OBSTETRICS

miR-200a Inhibits Tumor Proliferation by Targeting AP-2γ in Neuroblastoma Cells

(2014) Shun-Li Gao et al.   Asian Pacific Journal of Cancer Prevention

The other side of the coin: The tumor-suppressive aspect of oncogenes and the oncogenic aspect of tumor-suppressive genes, such as those along the CCND–CDK4/6–RB axis

(2014) Xiaomin Lou et al.   CELL CYCLE

AP-2α is required after lens vesicle formation to maintain lens integrity

(2014) Christine L. Kerr et al.   DEVELOPMENTAL DYNAMICS

TFClass: a classification of human transcription factors and their rodent orthologs

(2014) Edgar Wingender et al.   NUCLEIC ACIDS RESEARCH

Effect of Dedifferentiation on Time to Mutation Acquisition in Stem Cell-Driven Cancers

(2014) Alexandra Jilkine et al.   PLoS Computational Biology

TFAP2A Regulates Nasopharyngeal Carcinoma Growth and Survival by Targeting HIF-1  Signaling Pathway

(2013) D. Shi et al.   Cancer Prevention Research

miR-214 Coordinates Melanoma Progression by Upregulating ALCAM through TFAP2 and miR-148b Downmodulation

(2013) Elisa Penna et al.   CANCER RESEARCH

Prdm1a directly activates foxd3 and tfap2a during zebrafish neural crest specification

(2013) D. R. Powell et al.   DEVELOPMENT

Transcription factor AP-2α regulates acute myeloid leukemia cell proliferation by influencing Hoxa gene expression

(2013) Xiaofeng Ding et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Analysis of the Human Tissue-specific Expression by Genome-wide Integration of Transcriptomics and Antibody-based Proteomics

(2013) Linn Fagerberg et al.   MOLECULAR & CELLULAR PROTEOMICS

Human Melanoma Cells Over-Express Extracellular Matrix 1 (ECM1) Which Is Regulated by TFAP2C

(2013) Geeta Lal et al.   PLoS One

MicroRNA-17-92, a Direct Ap-2α Transcriptional Target, Modulates T-Box Factor Activity in Orofacial Clefting

(2013) Jun Wang et al.   PLoS Genetics

Environmental epigenetics: prospects for studying epigenetic mediation of exposure–response relationships

(2012) Victoria K. Cortessis et al.   HUMAN GENETICS

Expression of AP-2α, AP-2γ and ESDN in primary melanomas: Correlation with histopathological features and potential prognostic value

(2012) Simona Osella-Abate et al.   JOURNAL OF DERMATOLOGICAL SCIENCE

Histone Demethylase KDM5B Collaborates with TFAP2C and Myc To Repress the Cell Cycle Inhibitor p21cip (CDKN1A)

(2012) P.-P. Wong et al.   MOLECULAR AND CELLULAR BIOLOGY

The role of transcription factor Tcfap2c/TFAP2C in trophectoderm development

(2012) Peter Kuckenberg et al.   REPRODUCTIVE BIOMEDICINE ONLINE

Reversal of epigenetic silencing of AP-2alpha results in increased zinc uptake in DU-145 and LNCaP prostate cancer cells

(2011) Peter B. Makhov et al.   CARCINOGENESIS

microRNA-214 contributes to melanoma tumour progression through suppression of TFAP2C

(2011) Elisa Penna et al.   EMBO JOURNAL

The role of BLIMP1 and its putative downstream target TFAP2C in germ cell development and germ cell tumours

(2011) S. Schäfer et al.   INTERNATIONAL JOURNAL OF ANDROLOGY

Aberrant Expressions of AP-2α Splice Variants in Pancreatic Cancer

(2011) Catherine Carrière et al.   PANCREAS

Reduced Expression of Transcription Factor AP-2α Is Associated with Gastric Adenocarcinoma Prognosis

(2011) Wei Wang et al.   PLoS One

A miR-200b/200c/429-Binding Site Polymorphism in the 3′ Untranslated Region of the AP-2α Gene Is Associated with Cisplatin Resistance

(2011) Yuan Wu et al.   PLoS One

Dual association by TFAP2A during activation of the p21cip/CDKN1A promoter

(2010) Angelo G. Scibetta et al.   CELL CYCLE

WWOXgene and gene product: tumor suppression through specific protein interactions

(2010) Zaidoun Salah et al.   Future Oncology

Identification of primary gene targets of TFAP2C in hormone responsive breast carcinoma cells

(2010) George W. Woodfield et al.   GENES CHROMOSOMES & CANCER

A complexTFAP2Aallele is associated with branchio-oculo-facial syndrome and inner ear malformation in a deaf child

(2009) Mustafa Tekin et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

AP-2γ promotes proliferation in breast tumour cells by direct repression of the CDKN1A gene

(2009) Christopher M J Williams et al.   EMBO JOURNAL

Roles of AP-2 transcription factors in the regulation of cartilage and skeletal development

(2009) Ann-Kathrin Wenke et al.   FEBS Journal

Reduced TFAP2A function causes variable optic fissure closure and retinal defects and sensitizes eye development to mutations in other morphogenetic regulators

(2009) Gaia Gestri et al.   HUMAN GENETICS

AP-2α Induces Epigenetic Silencing of Tumor Suppressive Genes and Microsatellite Instability in Head and Neck Squamous Cell Carcinoma

(2009) Kristi L. Bennett et al.   PLoS One

Oxidative Stress and Oxidative Damage in Carcinogenesis

(2009) James E. Klaunig et al.   TOXICOLOGIC PATHOLOGY

TFAP2A Mutations Result in Branchio-Oculo-Facial Syndrome

(2008) Jeff M. Milunsky et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Transcription factor AP2alpha (TFAP2a) regulates differentiation and proliferation of neuroblastoma cells

(2008) Johannes H. Schulte et al.   CANCER LETTERS

Overexpression ofTFAP2Cin invasive breast cancer correlates with a poorer response to anti-hormone therapy and reduced patient survival

(2008) JMW Gee et al.   JOURNAL OF PATHOLOGY