Drosophila melanogaster mitochondrial Hsp22: a role in resistance to oxidative stress, aging and the mitochondrial unfolding protein response
出版年份 2015 全文链接
标题
Drosophila melanogaster mitochondrial Hsp22: a role in resistance to oxidative stress, aging and the mitochondrial unfolding protein response
作者
关键词
Hsp22, Small heat shock protein (sHSP), Oxidative stress, Reactive oxygen species (ROS), Mitochondrial unfolding protein response (UPR<sup>MT</sup>), Aging
出版物
BIOGERONTOLOGY
Volume 17, Issue 1, Pages 61-70
出版商
Springer Nature
发表日期
2015-07-08
DOI
10.1007/s10522-015-9591-y
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Longevity and stress in Caenorhabditis elegans
- (2016) Katherine I. Zhou et al. Aging-US
- Gene expression changes in response to aging compared to heat stress, oxidative stress and ionizing radiation in Drosophila melanogaster
- (2016) Gary Landis et al. Aging-US
- Mitochondrial proteases and protein quality control in ageing and longevity
- (2015) Marie-Paule Hamon et al. AGEING RESEARCH REVIEWS
- Mitochondrial maintenance failure in aging and role of sexual dimorphism
- (2015) John Tower ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
- Mitochondria: Much ado about nothing? How dangerous is reactive oxygen species production?
- (2015) Eliška Holzerová et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Molecular mechanisms mediating mitochondrial dynamics and mitophagy and their functional roles in the cardiovascular system
- (2015) Yoshiyuki Ikeda et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- A First Line of Stress Defense: Small Heat Shock Proteins and Their Function in Protein Homeostasis
- (2015) Martin Haslbeck et al. JOURNAL OF MOLECULAR BIOLOGY
- Mitochondrial and Cytoplasmic ROS Have Opposing Effects on Lifespan
- (2015) Claire E. Schaar et al. PLoS Genetics
- Mitochondrial effectors of cellular senescence: beyond the free radical theory of aging
- (2014) Dorian V. Ziegler et al. AGING CELL
- The Intrinsic Apoptosis Pathway Mediates the Pro-Longevity Response to Mitochondrial ROS in C. elegans
- (2014) Callista Yee et al. CELL
- Mitochondrial Proteostasis in the Control of Aging and Longevity
- (2014) Martin Borch Jensen et al. Cell Metabolism
- Mitohormesis: Promoting Health and Lifespan by Increased Levels of Reactive Oxygen Species (ROS)
- (2014) Michael Ristow et al. Dose-Response
- The mitochondrial unfolded protein response and increased longevity: Cause, consequence, or correlation?
- (2014) Christopher F. Bennett et al. EXPERIMENTAL GERONTOLOGY
- Mitochondrial stress: Balancing friend and foe
- (2014) Eva Diana Runkel et al. EXPERIMENTAL GERONTOLOGY
- Mitochondrial chaperone TRAP1 activates the mitochondrial UPR and extends healthspan in Drosophila
- (2014) Rehan M. Baqri et al. MECHANISMS OF AGEING AND DEVELOPMENT
- Activation of the mitochondrial unfolded protein response does not predict longevity in Caenorhabditis elegans
- (2014) Christopher F. Bennett et al. Nature Communications
- The role of protein clearance mechanisms in organismal ageing and age-related diseases
- (2014) David Vilchez et al. Nature Communications
- Mitochondrial stress signaling in longevity: A new role for mitochondrial function in aging
- (2014) Shauna Hill et al. Redox Biology
- Involvement of Redox State in the Aging of Drosophila melanogaster
- (2013) William C. Orr et al. ANTIOXIDANTS & REDOX SIGNALING
- The NAD+/Sirtuin Pathway Modulates Longevity through Activation of Mitochondrial UPR and FOXO Signaling
- (2013) Laurent Mouchiroud et al. CELL
- Aging, MnSOD, and hormesis mechanisms converge on liver mUPR
- (2013) Jie Shen et al. CELL CYCLE
- The mitochondrial unfolded protein response, a conserved stress response pathway with implications in health and disease
- (2013) V. Jovaisaite et al. JOURNAL OF EXPERIMENTAL BIOLOGY
- Variegated Expression of Hsp22 Transgenic Reporters Indicates Cell-specific Patterns of Aging in Drosophila Oenocytes
- (2013) John Tower et al. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
- Mitonuclear protein imbalance as a conserved longevity mechanism
- (2013) Riekelt H. Houtkooper et al. NATURE
- Longevity focuses on NAD+
- (2013) Heinrich Jasper Nature Chemical Biology
- Surveillance-Activated Defenses Block the ROS–Induced Mitochondrial Unfolded Protein Response
- (2013) Eva D. Runkel et al. PLoS Genetics
- Regulation of Lifespan by the Mitochondrial Electron Transport Chain: Reactive Oxygen Species-Dependent and Reactive Oxygen Species-Independent Mechanisms
- (2012) Filippo Scialo et al. ANTIOXIDANTS & REDOX SIGNALING
- Genetic analysis of mitochondrial protein misfolding in Drosophila melanogaster
- (2012) I Pimenta de Castro et al. CELL DEATH AND DIFFERENTIATION
- Impaired Insulin/IGF1 Signaling Extends Life Span by Promoting Mitochondrial L-Proline Catabolism to Induce a Transient ROS Signal
- (2012) Kim Zarse et al. Cell Metabolism
- Sealing the Mitochondrial Respirasome
- (2012) D. R. Winge MOLECULAR AND CELLULAR BIOLOGY
- Mitochondrial Import Efficiency of ATFS-1 Regulates Mitochondrial UPR Activation
- (2012) A. M. Nargund et al. SCIENCE
- Protective Coupling of Mitochondrial Function and Protein Synthesis via the eIF2α Kinase GCN-2
- (2012) Brooke M. Baker et al. PLoS Genetics
- Redox Sensing by Proteins: Oxidative Modifications on Cysteines and the Consequent Events
- (2011) Ying Wang et al. ANTIOXIDANTS & REDOX SIGNALING
- A Protein Complex Network of Drosophila melanogaster
- (2011) K.G. Guruharsha et al. CELL
- The Cell-Non-Autonomous Nature of Electron Transport Chain-Mediated Longevity
- (2011) Jenni Durieux et al. CELL
- Extending life span by increasing oxidative stress
- (2011) Michael Ristow et al. FREE RADICAL BIOLOGY AND MEDICINE
- Reactive oxygen species are not involved in the onset of age-related memory impairment inDrosophila
- (2011) Y. Hirano et al. GENES BRAIN AND BEHAVIOR
- Two modes of mitochondrial dysfunction lead independently to lifespan extension in Caenorhabditis elegans
- (2010) Wen Yang et al. AGING CELL
- Mitochondrial ROS Generation and Its Regulation: Mechanisms Involved in H2O2 Signaling
- (2010) Michel Rigoulet et al. ANTIOXIDANTS & REDOX SIGNALING
- FOXO/4E-BP Signaling in Drosophila Muscles Regulates Organism-wide Proteostasis during Aging
- (2010) Fabio Demontis et al. CELL
- The mitochondrial UPR - protecting organelle protein homeostasis
- (2010) C. M. Haynes et al. JOURNAL OF CELL SCIENCE
- The Matrix Peptide Exporter HAF-1 Signals a Mitochondrial UPR by Activating the Transcription Factor ZC376.7 in C. elegans
- (2010) Cole M. Haynes et al. MOLECULAR CELL
- Gene Expression in a Drosophila Model of Mitochondrial Disease
- (2010) Daniel J. M. Fernández-Ayala et al. PLoS One
- Extension of Drosophila Life Span by RNAi of the Mitochondrial Respiratory Chain
- (2009) Jeffrey M. Copeland et al. CURRENT BIOLOGY
- Gene expression profiling implicates OXPHOS complexes in lifespan extension of flies over-expressing a small mitochondrial chaperone, Hsp22
- (2009) Hyun-Ju Kim et al. EXPERIMENTAL GERONTOLOGY
- Hyperoxia-induced neurodegeneration as a tool to identify neuroprotective genes in Drosophila melanogaster
- (2009) Christoph Gruenewald et al. FREE RADICAL BIOLOGY AND MEDICINE
- Proproliferative Functions ofDrosophilaSmall Mitochondrial Heat Shock Protein 22 in Human Cells
- (2009) Renu Wadhwa et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Cytoplasmic functions of the tumour suppressor p53
- (2009) Douglas R. Green et al. NATURE
- A Regulated Response to Impaired Respiration Slows Behavioral Rates and Increases Lifespan in Caenorhabditis elegans
- (2009) David Cristina et al. PLoS Genetics
- Life span alteration after irradiation in Drosophila melanogaster strains with mutations of Hsf and Hsps
- (2008) A. Moskalev et al. BIOGERONTOLOGY
- FOXO-regulated transcription restricts overgrowth ofTscmutant organs
- (2008) Kieran F. Harvey et al. JOURNAL OF CELL BIOLOGY
- Distinct mitochondrial retrograde signals control the G1-S cell cycle checkpoint
- (2008) Edward Owusu-Ansah et al. NATURE GENETICS
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