Exploring the Impact of Single-Nucleotide Polymorphisms on Translation

RNA regulons in cancer and inflammation

(2018) Laura Simone Bisogno et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Loss-of-function uORF mutations in human malignancies

(2018) Julia Schulz et al.   Scientific Reports

Codon optimality, bias and usage in translation and mRNA decay

(2017) Gavin Hanson et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Cap-binding protein 4EHP effects translation silencing by microRNAs

(2017) Clément Chapat et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

SNPs in microRNA target sites and their potential role in human disease

(2017) Adrianna Moszyńska et al.   Open Biology

Alteration of protein function by a silent polymorphism linked to tRNA abundance

(2017) Sebastian Kirchner et al.   PLOS BIOLOGY

Viral internal ribosomal entry sites: four classes for one goal

(2017) Justine Mailliot et al.   Wiley Interdisciplinary Reviews-RNA

Genome-Wide Analysis of RNA Secondary Structure

(2016) Philip C. Bevilacqua et al.   Annual Review of Genetics

Translational control by 5'-untranslated regions of eukaryotic mRNAs

(2016) A. G. Hinnebusch et al.   SCIENCE

Genetic variation rs7930 in the miR-4273-5p target site is associated with a risk of colorectal cancer

(2016) Ah-Reum Lee et al.   OncoTargets and Therapy

Improved Ribosome-Footprint and mRNA Measurements Provide Insights into Dynamics and Regulation of Yeast Translation

(2016) David E. Weinberg et al.   Cell Reports

eIF4E-mediated translational control of cancer incidence

(2015) Peter B. Bitterman et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Targeting the eIF4F Translation Initiation Complex: A Critical Nexus for Cancer Development

(2015) J. Pelletier et al.   CANCER RESEARCH

Single nucleotide polymorphisms in clinics: Fantasy or reality for cancer?

(2015) Srilakshmi Srinivasan et al.   CRITICAL REVIEWS IN CLINICAL LABORATORY SCIENCES

A common polymorphism in the 5′ UTR of ERCC5 creates an upstream ORF that confers resistance to platinum-based chemotherapy

(2015) Joanna Somers et al.   GENES & DEVELOPMENT

Overview of MicroRNA Biology

(2015) Ashley Mohr et al.   SEMINARS IN LIVER DISEASE

Understanding Biases in Ribosome Profiling Experiments Reveals Signatures of Translation Dynamics in Yeast

(2015) Jeffrey A. Hussmann et al.   PLoS Genetics

Exploring Internal Ribosome Entry Sites as Therapeutic Targets

(2015) Anton A. Komar et al.   Frontiers in Oncology

mrSNP: Software to detect SNP effects on microRNA binding

(2014) Mehmet Deveci et al.   BMC BIOINFORMATICS

Measurement of average decoding rates of the 61 sense codons in vivo

(2014) Justin Gardin et al.   eLife

Distinct stages of the translation elongation cycle revealed by sequencing ribosome-protected mRNA fragments

(2014) Liana F Lareau et al.   eLife

Computational SNP Analysis: Current Approaches and Future Prospects

(2013) Ambuj Kumar et al.   CELL BIOCHEMISTRY AND BIOPHYSICS

Proteome-Wide Characterization of the RNA-Binding Protein RALY-Interactome Using the in Vivo-Biotinylation-Pulldown-Quant (iBioPQ) Approach

(2013) Stefan Tenzer et al.   JOURNAL OF PROTEOME RESEARCH

System-wide identification of RNA-binding proteins by interactome capture

(2013) Alfredo Castello et al.   Nature Protocols

Dopa-Responsive Dystonia: Functional Analysis of Single Nucleotide Substitutions within the 5’ Untranslated GCH1 Region

(2013) Ioanna A. Armata et al.   PLoS One

Genome-wide search for exonic variants affecting translational efficiency

(2013) Quan Li et al.   Nature Communications

Gene Expression Regulation by Upstream Open Reading Frames and Human Disease

(2013) Cristina Barbosa et al.   PLoS Genetics

Translational control by 3'-UTR-binding proteins

(2012) E. Szostak et al.   Briefings in Functional Genomics

A program for annotating and predicting the effects of single nucleotide polymorphisms, SnpEff

(2012) Pablo Cingolani et al.   FLY

A Novel 4EHP-GIGYF2 Translational Repressor Complex Is Essential for Mammalian Development

(2012) M. Morita et al.   MOLECULAR AND CELLULAR BIOLOGY

An integrated encyclopedia of DNA elements in the human genome

(2012)   NATURE

Single Nucleotide Polymorphisms Can Create Alternative Polyadenylation Signals and Affect Gene Expression through Loss of MicroRNA-Regulation

(2012) Laurent F. Thomas et al.   PLoS Computational Biology

Screening of Kozak-motif-located SNPs and analysis of their association with human diseases

(2010) Heng Xu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

A Role for Codon Order in Translation Dynamics

(2010) Gina Cannarozzi et al.   CELL

MicroSNiPer: a web tool for prediction of SNP effects on putative microRNA targets

(2010) Maxim Barenboim et al.   HUMAN MUTATION

A method and server for predicting damaging missense mutations

(2010) Ivan A Adzhubei et al.   NATURE METHODS

5'-UTR G-quadruplex structures acting as translational repressors

(2010) J.-D. Beaudoin et al.   NUCLEIC ACIDS RESEARCH

Variation in Transcription Factor Binding Among Humans

(2010) M. Kasowski et al.   SCIENCE

Regulation of Translation Initiation in Eukaryotes: Mechanisms and Biological Targets

(2009) Nahum Sonenberg et al.   CELL

Nonsense-mediated mRNA decay in human cells: mechanistic insights, functions beyond quality control and the double-life of NMD factors

(2009) Pamela Nicholson et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Predicting the effects of coding non-synonymous variants on protein function using the SIFT algorithm

(2009) Prateek Kumar et al.   Nature Protocols

Upstream open reading frames cause widespread reduction of protein expression and are polymorphic among humans

(2009) S. E. Calvo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Requirement of RNA Binding of Mammalian Eukaryotic Translation Initiation Factor 4GI (eIF4GI) for Efficient Interaction of eIF4E with the mRNA Cap

(2008) A. Yanagiya et al.   MOLECULAR AND CELLULAR BIOLOGY

Increased nucleotide polymorphic changes in the 5′-untranslated region of δ-catenin (CTNND2) gene in prostate cancer

(2008) T Wang et al.   ONCOGENE

Proliferating Cells Express mRNAs with Shortened 3' Untranslated Regions and Fewer MicroRNA Target Sites

(2008) R. Sandberg et al.   SCIENCE