Computational SNP Analysis: Current Approaches and Future Prospects

Drug resistance mechanism of PncA inMycobacterium tuberculosis

(2013) Vidya Rajendran et al.   JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS

Role of ELA region in auto-activation of mutant KIT receptor: a molecular dynamics simulation insight

(2013) Rituraj Purohit   JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS

Cancer Associated E17K Mutation Causes Rapid Conformational Drift in AKT1 Pleckstrin Homology (PH) Domain

(2013) Ambuj Kumar et al.   PLoS One

Computational investigation of pathogenic nsSNPs in CEP63 protein

(2012) Ambuj Kumar et al.   GENE

In silico analysis of Single Nucleotide Polymorphisms (SNPs) in human BRAF gene

(2012) Muhammad Ramzan Manwar Hussain et al.   GENE

Exploration of deleterious single nucleotide polymorphisms in late-onset Alzheimer disease susceptibility genes

(2012) Tariq Ahmad Masoodi et al.   GENE

Mutational analysis of TYR gene and its structural consequences in OCA1A

(2012) Balu K et al.   GENE

Functional genomics based prioritization of potential nsSNPs in EPHX1, GSTT1, GSTM1 and GSTP1 genes for breast cancer susceptibility studies

(2012) Tariq Ahmad Masoodi et al.   GENOMICS

SNP Selection and Classification of Genome-Wide SNP Data Using Stratified Sampling Random Forests

(2012) Qingyao Wu et al.   IEEE TRANSACTIONS ON NANOBIOSCIENCE

Studies on Adaptability of Binding Residues Flap Region of TMC-114 Resistance HIV-1 Protease Mutants

(2012) Rituraj Purohit et al.   JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS

Computational screening and molecular dynamics simulation of disease associated nsSNPs in CENP-E

(2012) Ambuj Kumar et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

In silico prediction of a disease-associated STIL mutant and its affect on the recruitment of centromere protein J (CENPJ)

(2012) Ambuj Kumar et al.   FEBS Open Bio

In silico investigation of molecular mechanism of laminopathy caused by a point mutation (R482W) in lamin A/C protein

(2011) Vidya Rajendran et al.   AMINO ACIDS

A new disease-specific machine learning approach for the prediction of cancer-causing missense variants

(2011) Emidio Capriotti et al.   GENOMICS

Performance of mutation pathogenicity prediction methods on missense variants

(2011) Janita Thusberg et al.   HUMAN MUTATION

SNPeffect 4.0: on-line prediction of molecular and structural effects of protein-coding variants

(2011) G. De Baets et al.   NUCLEIC ACIDS RESEARCH

Relationship between mutation of serine residue at 315th position in M. tuberculosis catalase-peroxidase enzyme and Isoniazid susceptibility: An in silico analysis

(2010) Rituraj Purohit et al.   JOURNAL OF MOLECULAR MODELING

MuD: an interactive web server for the prediction of non-neutral substitutions using protein structural data

(2010) Gilad Wainreb et al.   NUCLEIC ACIDS RESEARCH

Prediction of Deleterious Non-Synonymous SNPs Based on Protein Interaction Network and Hybrid Properties

(2010) Tao Huang et al.   PLoS One

Automated inference of molecular mechanisms of disease from amino acid substitutions

(2009) B. Li et al.   BIOINFORMATICS

Functional annotations improve the predictive score of human disease-related mutations in proteins

(2009) Remo Calabrese et al.   HUMAN MUTATION

Structural basis for the resilience of Darunavir (TMC114) resistance major flap mutations of HIV-1 protease

(2009) Rituraj Purohit et al.   Interdisciplinary Sciences-Computational Life Sciences

SNAP predicts effect of mutations on protein function

(2008) Yana Bromberg et al.   BIOINFORMATICS

A three-state prediction of single point mutations on protein stability changes

(2008) Emidio Capriotti et al.   BMC BIOINFORMATICS

Direct observation of fast protein conformational switching

(2008) H. Ishikawa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Distance-scaled, finite ideal-gas reference state improves structure-derived potentials of mean force for structure selection and stability prediction

(2002) Hongyi Zhou et al.   PROTEIN SCIENCE