Revisiting the Concept of Targeting NFAT to Control T Cell Immunity and Autoimmune Diseases
出版年份 2018 全文链接
标题
Revisiting the Concept of Targeting NFAT to Control T Cell Immunity and Autoimmune Diseases
作者
关键词
-
出版物
Frontiers in Immunology
Volume 9, Issue -, Pages -
出版商
Frontiers Media SA
发表日期
2018-11-27
DOI
10.3389/fimmu.2018.02747
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Activation of Th2 cells downregulates CRTh2 through an NFAT1 mediated mechanism
- (2018) Emily MacLean Scott et al. PLoS One
- microRNA cluster 106a~363 is involved in T helper 17 cell differentiation
- (2017) Marc Kästle et al. IMMUNOLOGY
- Ubiquitin specific peptidase 4 stabilizes interferon regulatory factor protein and promotes its function to facilitate interleukin-4 expression in T helper type 2 cells
- (2017) Zhixiang Guo et al. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
- Downregulation of NFAT3 Due to Lack of T-Box Transcription Factor TBX5 Is Crucial for Cytokine Expression in T Cells
- (2017) Osamu Kaminuma et al. JOURNAL OF IMMUNOLOGY
- IL-21 restricts T follicular regulatory T cell proliferation through Bcl-6 mediated inhibition of responsiveness to IL-2
- (2017) Christoph Jandl et al. Nature Communications
- The Immunosuppressor ST1959, a 3,5-Diaryl-S-Triazole Derivative, Inhibits T Cell Activation by Reducing NFAT Nuclear Residency
- (2017) R. Lindstedt et al. INTERNATIONAL JOURNAL OF IMMUNOPATHOLOGY AND PHARMACOLOGY
- The effectiveness of new triple combination therapy using synthetic disease-modifying anti-rheumatic drugs with different pharmacological function against rheumatoid arthritis: the verification by an in vitro and clinical study
- (2016) Takuya Hirai et al. CLINICAL RHEUMATOLOGY
- Store-Operated Ca 2+ Entry in Follicular T Cells Controls Humoral Immune Responses and Autoimmunity
- (2016) Martin Vaeth et al. IMMUNITY
- Context-dependent regulation of Th17-associated genes and IFNγ expression by the transcription factor NFAT5
- (2016) Maria Alberdi et al. IMMUNOLOGY AND CELL BIOLOGY
- Cutting Edge: NFAT Transcription Factors Promote the Generation of Follicular Helper T Cells in Response to Acute Viral Infection
- (2016) Gustavo J. Martinez et al. JOURNAL OF IMMUNOLOGY
- Efficacy of add-on tacrolimus on methotrexate to maintain clinical remission after rediscontinuation of a tumor necrosis factor inhibitor in rheumatoid arthritis patients who relapsed shortly after discontinuation of the same tumor necrosis factor inhibitor due to clinical remission
- (2016) Taio Naniwa et al. Modern Rheumatology
- Th17/Treg Imbalance Induced by Dietary Salt Variation Indicates Inflammation of Target Organs in Humans
- (2016) Tao Luo et al. Scientific Reports
- miR-20b Inhibits T Cell Proliferation and Activation via NFAT Signaling Pathway in Thymoma-Associated Myasthenia Gravis
- (2016) Yanzhong Xin et al. Biomed Research International
- NFATc1 deficiency in T cells protects mice from experimental autoimmune encephalomyelitis
- (2015) Sarah Reppert et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- NFAT1 deficit and NFAT2 deficit attenuate EAE via different mechanisms
- (2015) Lena Dietz et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- The Interleukin-2-mTORc1 Kinase Axis Defines the Signaling, Differentiation, and Metabolism of T Helper 1 and Follicular B Helper T Cells
- (2015) John P. Ray et al. IMMUNITY
- Inhibition of FOXP3/NFAT Interaction Enhances T Cell Function after TCR Stimulation
- (2015) Teresa Lozano et al. JOURNAL OF IMMUNOLOGY
- Immunodeficiency and Autoimmune Enterocolopathy Linked to NFAT5 Haploinsufficiency
- (2015) Brigid S. Boland et al. JOURNAL OF IMMUNOLOGY
- LEF-1 and TCF-1 orchestrate TFH differentiation by regulating differentiation circuits upstream of the transcriptional repressor Bcl6
- (2015) Youn Soo Choi et al. NATURE IMMUNOLOGY
- Selective NFAT targeting in T cells ameliorates GvHD while maintaining antitumor activity
- (2015) Martin Vaeth et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Concomitant methotrexate and tacrolimus augment the clinical response to abatacept in patients with rheumatoid arthritis with a prior history of biological DMARD use
- (2015) Nobunori Takahashi et al. RHEUMATOLOGY INTERNATIONAL
- dNP2 is a blood–brain barrier-permeable peptide enabling ctCTLA-4 protein delivery to ameliorate experimental autoimmune encephalomyelitis
- (2015) Sangho Lim et al. Nature Communications
- Function of a Foxp3 cis -Element in Protecting Regulatory T Cell Identity
- (2014) Xudong Li et al. CELL
- Orphan nuclear receptor NR2F6 acts as an essential gatekeeper of Th17 CD4+ T cell effector functions
- (2014) Natascha Hermann-Kleiter et al. Cell Communication and Signaling
- Follicular regulatory T cells control humoral autoimmunity via NFAT2-regulated CXCR5 expression
- (2014) Martin Vaeth et al. JOURNAL OF EXPERIMENTAL MEDICINE
- NFATc1 Regulates PD-1 Expression upon T Cell Activation
- (2014) K. J. Oestreich et al. JOURNAL OF IMMUNOLOGY
- Transcription factor achaete-scute homologue 2 initiates follicular T-helper-cell development
- (2014) Xindong Liu et al. NATURE
- Patient Age and the Prognosis of Idiopathic Membranous Nephropathy
- (2014) Makoto Yamaguchi et al. PLoS One
- The effect of aging on the frequency, phenotype and cytokine production of human blood CD4 + CXCR5 + T follicular helper cells: comparison of aged and young subjects
- (2014) Maohua Zhou et al. Immunity & Ageing
- Transcriptional regulation of kinases downstream of the T cell receptor: another immunomodulatory mechanism of glucocorticoids
- (2014) Maria Grazia Petrillo et al. BMC Pharmacology & Toxicology
- Antiproliferative, antiandrogenic and cytotoxic effects of novel caffeic acid derivatives in LNCaP human androgen-dependent prostate cancer cells
- (2013) J. Thomas Sanderson et al. BIOORGANIC & MEDICINAL CHEMISTRY
- MiR-568 inhibits the activation and function of CD4+ T cells and Treg cells by targeting NFAT5
- (2013) Wei Li et al. INTERNATIONAL IMMUNOLOGY
- NFATc1 Induction in Peripheral T and B Lymphocytes
- (2013) M. Hock et al. JOURNAL OF IMMUNOLOGY
- Calcineurin Inhibitors: 40 Years Later, Can't Live Without ...
- (2013) J. R. Azzi et al. JOURNAL OF IMMUNOLOGY
- Calcineurin inhibitor induces pain hypersensitivity by potentiating pre- and postsynaptic NMDA receptor activity in spinal cords
- (2013) Shao-Rui Chen et al. JOURNAL OF PHYSIOLOGY-LONDON
- Genistein inhibits hepatocellular carcinoma cell migration by reversing the epithelial-mesenchymal transition: Partial mediation by the transcription factor NFAT1
- (2013) Weiqi Dai et al. MOLECULAR CARCINOGENESIS
- Sodium chloride drives autoimmune disease by the induction of pathogenic TH17 cells
- (2013) Markus Kleinewietfeld et al. NATURE
- NFAT5 induction by the pre-T-cell receptor serves as a selective survival signal in T-lymphocyte development
- (2013) R. Berga-Bolanos et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Functional STAT3 deficiency compromises the generation of human T follicular helper cells
- (2012) C. S. Ma et al. BLOOD
- Membrane microdomain organization, calcium signal, and NFAT activation as an important axis in polarized Th cell function
- (2012) Emese Izsepi et al. CYTOMETRY PART A
- Anti-proliferative activity and protection against oxidative DNA damage by punicalagin isolated from pomegranate husk
- (2012) Farrukh Aqil et al. FOOD RESEARCH INTERNATIONAL
- Increased immunosuppressive function of CD4+CD25+Foxp3+GITR+ T regulatory cells from NFATc2(−/−) mice controls allergen-induced experimental asthma
- (2012) Roman Karwot et al. IMMUNOBIOLOGY
- Cell permeable NFAT inhibitory peptide Sim-2-VIVIT inhibits T-cell activation and alleviates allergic airway inflammation and hyper-responsiveness
- (2012) Je-Min Choi et al. IMMUNOLOGY LETTERS
- Nuclear orphan receptor NR2F6 directly antagonizes NFAT and RORγt binding to the Il17a promoter
- (2012) Natascha Hermann-Kleiter et al. JOURNAL OF AUTOIMMUNITY
- Gene expression induced by Toll-like receptors in macrophages requires the transcription factor NFAT5
- (2012) Maria Buxadé et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Constitutive Nuclear Localization of NFAT in Foxp3+ Regulatory T Cells Independent of Calcineurin Activity
- (2012) Q. Li et al. JOURNAL OF IMMUNOLOGY
- Imperatorin sensitizes anoikis and inhibits anchorage-independent growth of lung cancer cells
- (2012) Kanuengnit Choochuay et al. Journal of Natural Medicines
- Are calcineurin inhibitors safer than mTOR inhibitors?
- (2012) Heidi Yeh et al. Nature Reviews Nephrology
- Balanced interactions of calcineurin with AKAP79 regulate Ca2+–calcineurin–NFAT signaling
- (2012) Huiming Li et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Transcription factor IRF4 determines germinal center formation through follicular T-helper cell differentiation
- (2012) N. Bollig et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Dependence on nuclear factor of activated T-cells (NFAT) levels discriminates conventional T cells from Foxp3+ regulatory T cells
- (2012) M. Vaeth et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Helenalin-induced apoptosis is dependent on production of reactive oxygen species and independent of induction of endoplasmic reticulum stress in renal cell carcinoma
- (2012) Ji Hoon Jang et al. TOXICOLOGY IN VITRO
- In Vitro Effects of Cyclosporine A and Tacrolimus on Regulatory T-Cell Proliferation and Function
- (2012) Céline Miroux et al. TRANSPLANTATION
- Follicular Helper CD4 T Cells (TFH)
- (2011) Shane Crotty Annual Review of Immunology
- Coordinated regulation of IL-4 and IL-13 expression in human T cells: 3C analysis for DNA looping
- (2011) Xin Yao et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- RANKL induces NFATc1 acetylation and stability via histone acetyltransferases during osteoclast differentiation
- (2011) Jung Ha Kim et al. BIOCHEMICAL JOURNAL
- Disruption of a Nuclear NFATc2 Protein Stabilization Loop Confers Breast and Pancreatic Cancer Growth Suppression by Zoledronic Acid
- (2011) Shiv K. Singh et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- NFATc1 affects mouse splenic B cell function by controlling the calcineurin–NFAT signaling network
- (2011) Sankar Bhattacharyya et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Transcriptional activation of the IL31 gene by NFAT and STAT6
- (2011) Keunhee Park et al. JOURNAL OF LEUKOCYTE BIOLOGY
- The transcription factor BATF controls the global regulators of class-switch recombination in both B cells and T cells
- (2011) Wataru Ise et al. NATURE IMMUNOLOGY
- Enhanced Chromatin Accessibility and Recruitment of JUNB Mediate the Sustained IL-4 Expression in NFAT1 Deficient T Helper 2 Cells
- (2011) Jun-Seock Son et al. PLoS One
- Molecular Basis of Calcium Signaling in Lymphocytes: STIM and ORAI
- (2010) Patrick G. Hogan et al. Annual Review of Immunology
- Sequential Activation of NFAT and c-Myc Transcription Factors Mediates the TGF-β Switch from a Suppressor to a Promoter of Cancer Cell Proliferation
- (2010) Garima Singh et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Batf coordinates multiple aspects of B and T cell function required for normal antibody responses
- (2010) Briana C. Betz et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Calcineurin regulates innate antifungal immunity in neutrophils
- (2010) Matthew B. Greenblatt et al. JOURNAL OF EXPERIMENTAL MEDICINE
- NFAT5 Regulates T Lymphocyte Homeostasis and CD24-Dependent T Cell Expansion under Pathologic Hypernatremia
- (2010) R. Berga-Bolanos et al. JOURNAL OF IMMUNOLOGY
- Generation of pathogenic TH17 cells in the absence of TGF-β signalling
- (2010) Kamran Ghoreschi et al. NATURE
- Hyperactivation of nuclear factor of activated T cells 1 (NFAT1) in T cells attenuates severity of murine autoimmune encephalomyelitis
- (2010) S. Ghosh et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- IL-17 and Th17 Cells
- (2009) Thomas Korn et al. Annual Review of Immunology
- Runx3 inhibits IL-4 production in T cells via physical interaction with NFAT
- (2009) Sung Ho Lee et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Studies on the interactions of kaempferol to calcineurin by spectroscopic methods and docking
- (2009) Hong Lei et al. BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS
- Follicular Helper T Cells: Lineage and Location
- (2009) Nicolas Fazilleau et al. IMMUNITY
- The Transcriptional Repressor Bcl-6 Directs T Follicular Helper Cell Lineage Commitment
- (2009) Di Yu et al. IMMUNITY
- Calcineurin inactivation leads to decreased responsiveness to LPS in macrophages and dendritic cells and protects against LPS-induced toxicity in vivo
- (2009) Charay Jennings et al. Innate Immunity
- Early Growth Response Protein-1 (Egr-1) Is Preferentially Expressed in T Helper Type 2 (Th2) Cells and Is Involved in Acute Transcription of the Th2 Cytokine Interleukin-4
- (2009) Michael Lohoff et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Sumoylation of the Transcription Factor NFATc1 Leads to Its Subnuclear Relocalization and Interleukin-2 Repression by Histone Deacetylase
- (2009) Arnab Nayak et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- IL-31-IL-31R Interactions Limit the Magnitude of Th2 Cytokine-Dependent Immunity and Inflammation following Intestinal Helminth Infection
- (2009) Jacqueline G. Perrigoue et al. JOURNAL OF IMMUNOLOGY
- The New Salicylate Derivative UR-1505 Modulates the Th2/Humoral Response in a Dextran Sodium Sulphate Model of Colitis That Resembles Ulcerative Colitis
- (2009) Elvira Bailón et al. JOURNAL OF PHARMACOLOGICAL SCIENCES
- Tacrolimus differentially regulates the proliferation of conventional and regulatory CD4+ T cells
- (2009) Kazue Kogina et al. MOLECULES AND CELLS
- CD14 regulates the dendritic cell life cycle after LPS exposure through NFAT activation
- (2009) Ivan Zanoni et al. NATURE
- Inhibitory Effects of Cyclosporine on Human Regulatory T Cells In Vitro
- (2009) C. Miroux et al. TRANSPLANTATION PROCEEDINGS
- NFAT1 Transcription Factor Regulates Pulmonary Allergic Inflammation and Airway Responsiveness
- (2008) Bruna P. F. Fonseca et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- Regulatory T Cells and Immune Tolerance
- (2008) Shimon Sakaguchi et al. CELL
- Cyclosporin A inhibits the production of IL-17 by memory Th17 cells from healthy individuals and patients with rheumatoid arthritis
- (2008) Cai Zhang et al. CYTOKINE
- IL-23 and IL-17 in tuberculosis
- (2008) Shabaana A. Khader et al. CYTOKINE
- Regulatory T Cell-Derived Interleukin-10 Limits Inflammation at Environmental Interfaces
- (2008) Yuri P. Rubtsov et al. IMMUNITY
- Kaempferol: A new immunosuppressant of calcineurin
- (2008) Hu Wang et al. IUBMB LIFE
- The transcription factor NFATc2 controls IL-6–dependent T cell activation in experimental colitis
- (2008) Benno Weigmann et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Voclosporin (ISA247) for plaque psoriasis
- (2008) Poobalan Naidoo et al. LANCET
- The Foxp3+ regulatory T cell: a jack of all trades, master of regulation
- (2008) Qizhi Tang et al. NATURE IMMUNOLOGY
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