Calcineurin inhibitor induces pain hypersensitivity by potentiating pre- and postsynaptic NMDA receptor activity in spinal cords

Loss of calcineurin in the spinal dorsal horn contributes to neuropathic pain, and intrathecal administration of the phosphatase provides prolonged analgesia

(2013) Gordana Miletic et al.   PAIN

Chronic Opioid Potentiates Presynaptic but Impairs PostsynapticN-Methyl-d-aspartic Acid Receptor Activity in Spinal Cords

(2012) Yi-Lin Zhao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

N-Methyl-d-aspartate Receptor- and Calpain-mediated Proteolytic Cleavage of K+-Cl−Cotransporter-2 Impairs Spinal Chloride Homeostasis in Neuropathic Pain

(2012) Hong-Yi Zhou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Clinical features of calcineurin inhibitor-induced pain syndrome after allo-SCT

(2011) K Kakihana et al.   BONE MARROW TRANSPLANTATION

Effects of a calcineurin inhibitor, FK506, and a CCR5/CXCR3 antagonist, TAK-779, in a rat small intestinal transplantation model

(2011) Yuichi Takama et al.   TRANSPLANT IMMUNOLOGY

Triheteromeric NR1/NR2A/NR2B Receptors Constitute the MajorN-Methyl-d-aspartate Receptor Population in Adult Hippocampal Synapses

(2010) Claudia Rauner et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Antinociceptive effects of chronic administration of uncompetitive NMDA receptor antagonists in a rat model of diabetic neuropathic pain

(2009) Shao-Rui Chen et al.   NEUROPHARMACOLOGY

Ketamine produces effective and long-term pain relief in patients with Complex Regional Pain Syndrome Type 1

(2009) Marnix J. Sigtermans et al.   PAIN

Outpatient intravenous ketamine for the treatment of complex regional pain syndrome: A double-blind placebo controlled study

(2009) Robert J. Schwartzman et al.   PAIN

Calcineurin-inhibitor-induced pain syndrome after bone marrow transplantation

(2008) Yukiko Noda et al.   Journal of Anesthesia

Protein kinase CK2 modulates synaptic plasticity by modification of synaptic NMDA receptors in the hippocampus

(2008) Rie Kimura et al.   JOURNAL OF PHYSIOLOGY-LONDON