Crispr/Cas Mediated Deletion of PTPN22 in Jurkat T Cells Enhances TCR Signaling and Production of IL-2
出版年份 2018 全文链接
标题
Crispr/Cas Mediated Deletion of PTPN22 in Jurkat T Cells Enhances TCR Signaling and Production of IL-2
作者
关键词
-
出版物
Frontiers in Immunology
Volume 9, Issue -, Pages -
出版商
Frontiers Media SA
发表日期
2018-11-12
DOI
10.3389/fimmu.2018.02595
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Resistance to TGFβ suppression and improved anti-tumor responses in CD8+ T cells lacking PTPN22
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- Altered expression of protein tyrosine phosphatase, non-receptor type 22 isoforms in systemic lupus erythematosus
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- PTPN22 Silencing in the NOD Model Indicates the Type 1 Diabetes-Associated Allele Is Not a Loss-of-Function Variant
- (2012) P. Zheng et al. DIABETES
- PTPN22 Alters the Development of Regulatory T Cells in the Thymus
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- PTPN22.6, a Dominant Negative Isoform of PTPN22 and Potential Biomarker of Rheumatoid Arthritis
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- Lack of the Phosphatase PTPN22 Increases Adhesion of Murine Regulatory T Cells to Improve Their Immunosuppressive Function
- (2012) R. J. Brownlie et al. Science Signaling
- The balance of expression of PTPN22 splice forms is significantly different in rheumatoid arthritis patients compared with controls
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- Human T cells expressing affinity-matured TCR display accelerated responses but fail to recognize low density of MHC-peptide antigen
- (2011) S. Thomas et al. BLOOD
- The autoimmune disease–associated PTPN22 variant promotes calpain-mediated Lyp/Pep degradation associated with lymphocyte and dendritic cell hyperresponsiveness
- (2011) Jinyi Zhang et al. NATURE GENETICS
- Identification of a variant form of tyrosine phosphatase LYP
- (2010) Shaofeng Wang et al. BMC MOLECULAR BIOLOGY
- PTPN22 Deficiency Cooperates with the CD45 E613R Allele to Break Tolerance on a Non-Autoimmune Background
- (2009) J. Zikherman et al. JOURNAL OF IMMUNOLOGY
- PTPN22 R620W promotes production of anti-AChR autoantibodies and IL-2 in myasthenia gravis
- (2008) Ann Kari Lefvert et al. JOURNAL OF NEUROIMMUNOLOGY
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