Nucleotide Modifications Decrease Innate Immune Response Induced by Synthetic Analogs of snRNAs and snoRNAs

Characterization of primary normal and malignant breast cancer cell and their response to chemotherapy and immunostimulatory agents

(2018) Anna A. Nushtaeva et al.   BMC CANCER

Short Double-Stranded RNA with Immunostimulatory Activity: Sequence Dependence

(2018) Tatyana O. Kabilova et al.   Nucleic Acid Therapeutics

Pseudouridine Modification Inhibits Muscleblind-like 1 (MBNL1) Binding to CCUG Repeats and Minimally Structured RNA through Reduced RNA Flexibility

(2017) Elaine deLorimier et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Visualization of chemical modifications in the human 80S ribosome structure

(2017) S. Kundhavai Natchiar et al.   NATURE

Variety of RNAs in Peripheral Blood Cells, Plasma, and Plasma Fractions

(2017) Anna V. Savelyeva et al.   Biomed Research International

Many si/shRNAs can kill cancer cells by targeting multiple survival genes through an off-target mechanism

(2017) William Putzbach et al.   eLife

Serum snoRNAs as biomarkers for joint ageing and post traumatic osteoarthritis

(2017) Mandy M. F. Steinbusch et al.   Scientific Reports

Discriminating Self and Non-Self by RNA: Roles for RNA Structure, Misfolding, and Modification in Regulating the Innate Immune Sensor PKR

(2016) Chelsea M. Hull et al.   ACCOUNTS OF CHEMICAL RESEARCH

Analysis of RNA modifications by liquid chromatography–tandem mass spectrometry

(2016) Kathrin Thüring et al.   METHODS

Enrichr: a comprehensive gene set enrichment analysis web server 2016 update

(2016) Maxim V. Kuleshov et al.   NUCLEIC ACIDS RESEARCH

RNAs Containing Modified Nucleotides Fail To Trigger RIG-I Conformational Changes for Innate Immune Signaling

(2016) Ann Fiegen Durbin et al.   mBio

Cytosolic Accumulation of Small Nucleolar RNAs (snoRNAs) Is Dynamically Regulated by NADPH Oxidase

(2015) Christopher L. Holley et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

N6-methyladenosine-dependent RNA structural switches regulate RNA–protein interactions

(2015) Nian Liu et al.   NATURE

Single-nucleotide-resolution mapping of m6A and m6Am throughout the transcriptome

(2015) Bastian Linder et al.   NATURE METHODS

Potential role for snoRNAs in PKR activation during metabolic stress

(2015) Osama A. Youssef et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The emerging landscape of small nucleolar RNAs in cell biology

(2015) Fabien Dupuis-Sandoval et al.   Wiley Interdisciplinary Reviews-RNA

Targeted Knock-Down of miR21 Primary Transcripts Using snoMEN Vectors Induces Apoptosis in Human Cancer Cell Lines

(2015) Motoharu Ono et al.   PLoS One

Transcriptome-wide Mapping Reveals Widespread Dynamic-Regulated Pseudouridylation of ncRNA and mRNA

(2014) Schraga Schwartz et al.   CELL

Base Modification Strategies to Modulate Immune Stimulation by an siRNA

(2014) Rachel Anne P. Valenzuela et al.   CHEMBIOCHEM

Proteome–Metabolome Profiling of Ovarian Cancer Ascites Reveals Novel Components Involved in Intercellular Communication

(2014) Victoria O. Shender et al.   MOLECULAR & CELLULAR PROTEOMICS

Pseudouridine profiling reveals regulated mRNA pseudouridylation in yeast and human cells

(2014) Thomas M. Carlile et al.   NATURE

Annotation of long non-coding RNAs expressed in Collaborative Cross founder mice in response to respiratory virus infection reveals a new class of interferon-stimulated transcripts

(2014) Laurence Josset et al.   RNA Biology

Pattern Recognition and Signaling Mechanisms of RIG-I and MDA5

(2014) Stephanie Reikine et al.   Frontiers in Immunology

The centrality of RNA for engineering gene expression

(2013) James Chappell et al.   Biotechnology Journal

Characterization of human plasma-derived exosomal RNAs by deep sequencing

(2013) Xiaoyi Huang et al.   BMC GENOMICS

RNA catalyses nuclear pre-mRNA splicing

(2013) Sebastian M. Fica et al.   NATURE

N6-methyladenosine-dependent regulation of messenger RNA stability

(2013) Xiao Wang et al.   NATURE

Structural basis for viral 5′-PPP-RNA recognition by human IFIT proteins

(2013) Yazan M. Abbas et al.   NATURE

The contribution of pseudouridine to stabilities and structure of RNAs

(2013) Elzbieta Kierzek et al.   NUCLEIC ACIDS RESEARCH

Analysis of Human Protein Replacement Stable Cell Lines Established using snoMEN-PR Vector

(2013) Motoharu Ono et al.   PLoS One

Thermodynamic contribution and nearest-neighbor parameters of pseudouridine-adenosine base pairs in oligoribonucleotides

(2013) G. A. Hudson et al.   RNA

RNA pseudouridylation: new insights into an old modification

(2013) Junhui Ge et al.   TRENDS IN BIOCHEMICAL SCIENCES

Artificial Box C/D RNAs Affect Pre-mRNA Maturation in Human Cells

(2013) Grigoriy A. Stepanov et al.   Biomed Research International

Design of modified U1i molecules against HIV-1 RNA

(2012) Stefanie A. Knoepfel et al.   ANTIVIRAL RESEARCH

Innate immune agonist, dsRNA, induces apoptosis in ovarian cancer cells and enhances the potency of cytotoxic chemotherapeutics

(2012) Danielle N. Van et al.   FASEB JOURNAL

Ultraviolet radiation damages self noncoding RNA and is detected by TLR3

(2012) Jamie J Bernard et al.   NATURE MEDICINE

Differential gene and transcript expression analysis of RNA-seq experiments with TopHat and Cufflinks

(2012) Cole Trapnell et al.   Nature Protocols

Widespread occurrence of 5-methylcytosine in human coding and non-coding RNA

(2012) Jeffrey E. Squires et al.   NUCLEIC ACIDS RESEARCH

ViennaRNA Package 2.0

(2011) Ronny Lorenz et al.   Algorithms for Molecular Biology

Small Nucleolar RNAs U32a, U33, and U35a Are Critical Mediators of Metabolic Stress

(2011) Carlos I. Michel et al.   Cell Metabolism

IFIT1 is an antiviral protein that recognizes 5′-triphosphate RNA

(2011) Andreas Pichlmair et al.   NATURE IMMUNOLOGY

Increased in vivo inhibition of gene expression by combining RNA interference and U1 inhibition

(2011) Lorea Blazquez et al.   NUCLEIC ACIDS RESEARCH

Highly Efficient Reprogramming to Pluripotency and Directed Differentiation of Human Cells with Synthetic Modified mRNA

(2010) Luigi Warren et al.   Cell Stem Cell

Type I interferon: friend or foe?

(2010) Giorgio Trinchieri   JOURNAL OF EXPERIMENTAL MEDICINE

Small nucleolar RNA signatures as biomarkers for non-small-cell lung cancer

(2010) Jipei Liao et al.   Molecular Cancer

Spliceosomal snRNA modifications and their function

(2010) John Karijolich et al.   RNA Biology

A Quantitative Systems Approach Reveals Dynamic Control of tRNA Modifications during Cellular Stress

(2010) Clement T. Y. Chan et al.   PLoS Genetics

Short-hairpin RNAs delivered by lentiviral vector transduction trigger RIG-I-mediated IFN activation

(2009) Rachael Kenworthy et al.   NUCLEIC ACIDS RESEARCH

Nucleotide modifications in three functionally important regions of the Saccharomyces cerevisiae ribosome affect translation accuracy

(2009) Agnès Baudin-Baillieu et al.   NUCLEIC ACIDS RESEARCH

Protein-free small nuclear RNAs catalyze a two-step splicing reaction

(2009) S. Valadkhan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

5'-triphosphate RNA requires base-paired structures to activate antiviral signaling via RIG-I

(2009) A. Schmidt et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

5′-triphosphate-siRNA: turning gene silencing and Rig-I activation against melanoma

(2008) Hendrik Poeck et al.   NATURE MEDICINE

Functional importance of individual rRNA 2'-O-ribose methylations revealed by high-resolution phenotyping

(2008) J. Esguerra et al.   RNA