Autism-associated CHD8 deficiency impairs axon development and migration of cortical neurons

The Dynamic Landscape of Open Chromatin during Human Cortical Neurogenesis

(2018) Luis de la Torre-Ubieta et al.   CELL

Altered Neocortical Gene Expression, Brain Overgrowth and Functional Over-Connectivity in Chd8 Haploinsufficient Mice

(2018) Philipp Suetterlin et al.   CEREBRAL CORTEX

Dual Requirement of CHD8 for Chromatin Landscape Establishment and Histone Methyltransferase Recruitment to Promote CNS Myelination and Repair

(2018) Chuntao Zhao et al.   DEVELOPMENTAL CELL

Sexually dimorphic behavior, neuronal activity, and gene expression in Chd8-mutant mice

(2018) Hwajin Jung et al.   NATURE NEUROSCIENCE

Germline Chd8 haploinsufficiency alters brain development in mouse

(2017) Andrea L Gompers et al.   NATURE NEUROSCIENCE

Cellular and Circuitry Bases of Autism: Lessons Learned from the Temporospatial Manipulation of Autism Genes in the Brain

(2017) Samuel W. Hulbert et al.   Neuroscience Bulletin

Chd8 Mutation Leads to Autistic-like Behaviors and Impaired Striatal Circuits

(2017) Randall J. Platt et al.   Cell Reports

CRISPR/Cas9-mediated heterozygous knockout of the autism gene CHD8 and characterization of its transcriptional networks in cerebral organoids derived from iPS cells

(2017) Ping Wang et al.   Molecular Autism

CHD8 haploinsufficiency results in autistic-like phenotypes in mice

(2016) Yuta Katayama et al.   NATURE

Chd8 mediates cortical neurogenesis via transcriptional regulation of cell cycle and Wnt signaling

(2016) Omer Durak et al.   NATURE NEUROSCIENCE

Inducing amnesia through systemic suppression

(2016) Justin C. Hulbert et al.   Nature Communications

Autism spectrum disorders: from genes to neurobiology

(2015) A Jeremy Willsey et al.   CURRENT OPINION IN NEUROBIOLOGY

Excess of rare, inherited truncating mutations in autism

(2015) Niklas Krumm et al.   NATURE GENETICS

CRISPR/Cas9-mediated heterozygous knockout of the autism gene CHD8 and characterization of its transcriptional networks in neurodevelopment

(2015) Ping Wang et al.   Molecular Autism

Disruptive CHD8 Mutations Define a Subtype of Autism Early in Development

(2014) Raphael Bernier et al.   CELL

Synaptic, transcriptional and chromatin genes disrupted in autism

(2014) Silvia De Rubeis et al.   NATURE

The contribution of de novo coding mutations to autism spectrum disorder

(2014) Ivan Iossifov et al.   NATURE

CHD8regulates neurodevelopmental pathways associated with autism spectrum disorder in neural progenitors

(2014) Aarathi Sugathan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Detection of Clinically Relevant Genetic Variants in Autism Spectrum Disorder by Whole-Genome Sequencing

(2013) Yong-hui Jiang et al.   AMERICAN JOURNAL OF HUMAN GENETICS

The Angelman Syndrome Protein Ube3a Is Required for Polarized Dendrite Morphogenesis in Pyramidal Neurons

(2013) S. Miao et al.   JOURNAL OF NEUROSCIENCE

The autism brain imaging data exchange: towards a large-scale evaluation of the intrinsic brain architecture in autism

(2013) A Di Martino et al.   MOLECULAR PSYCHIATRY

Whole-Genome Sequencing in Autism Identifies Hot Spots for De Novo Germline Mutation

(2012) Jacob J. Michaelson et al.   CELL

Patterns and rates of exonic de novo mutations in autism spectrum disorders

(2012) Benjamin M. Neale et al.   NATURE

De novo mutations revealed by whole-exome sequencing are strongly associated with autism

(2012) Stephan J. Sanders et al.   NATURE

Sporadic autism exomes reveal a highly interconnected protein network of de novo mutations

(2012) Brian J. O’Roak et al.   NATURE

De Novo Gene Disruptions in Children on the Autistic Spectrum

(2012) Ivan Iossifov et al.   NEURON

Multiplex Targeted Sequencing Identifies Recurrently Mutated Genes in Autism Spectrum Disorders

(2012) B. J. O'Roak et al.   SCIENCE

Serum inducible kinase is a positive regulator of cortical dendrite development and is required for BDNF-promoted dendritic arborization

(2011) Shun-Ling Guo et al.   CELL RESEARCH

Autism spectrum disorders—A genetics review

(2011) Judith H Miles   GENETICS IN MEDICINE

Synaptic Wnt signaling—a contributor to major psychiatric disorders?

(2011) Nathan D. Okerlund et al.   Journal of Neurodevelopmental Disorders

Exome sequencing in sporadic autism spectrum disorders identifies severe de novo mutations

(2011) Brian J O'Roak et al.   NATURE GENETICS

Dendritic spine pathology in neuropsychiatric disorders

(2011) Peter Penzes et al.   NATURE NEUROSCIENCE

Review of neuroimaging in autism spectrum disorders: what have we learned and where we go from here

(2011) Evdokia Anagnostou et al.   Molecular Autism

TORC1 Regulates Activity-Dependent CREB-Target Gene Transcription and Dendritic Growth of Developing Cortical Neurons

(2009) S. Li et al.   JOURNAL OF NEUROSCIENCE

CHD8 suppresses p53-mediated apoptosis through histone H1 recruitment during early embryogenesis

(2009) Masaaki Nishiyama et al.   NATURE CELL BIOLOGY