Fibroblast growth factor 21 (FGF21) therapy attenuates left ventricular dysfunction and metabolic disturbance by improving FGF21 sensitivity, cardiac mitochondrial redox homoeostasis and structural changes in pre-diabetic rats

FGF21 attenuates pathological myocardial remodeling following myocardial infarction through the adiponectin-dependent mechanism

(2015) Yusuke Joki et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Fibroblast growth factor 21 protects the heart from apoptosis in a diabetic mouse model via extracellular signal-regulated kinase 1/2-dependent signalling pathway

(2015) Chi Zhang et al.   DIABETOLOGIA

FGF21 deletion exacerbates diabetic cardiomyopathy by aggravating cardiac lipid accumulation

(2015) Xiaoqing Yan et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Effects of fibroblast growth factor 21 on the heart

(2015) Pongpan Tanajak et al.   JOURNAL OF ENDOCRINOLOGY

Fibroblast growth factor (FGF21) protects mouse liver against d-galactose-induced oxidative stress and apoptosis via activating Nrf2 and PI3K/Akt pathways

(2015) Yinhang Yu et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Connexin43 Mediated Delivery of ADAMTS5 Targeting siRNAs from Mesenchymal Stem Cells to Synovial Fibroblasts

(2015) Shuo Liu et al.   PLoS One

Induction of Apoptosis in MCF-7 Cells via Oxidative Stress Generation, Mitochondria-Dependent and Caspase-Independent Pathway by Ethyl Acetate Extract of Dillenia suffruticosa and Its Chemical Profile

(2015) Yin Sim Tor et al.   PLoS One

Metallothionein-3 Increases Triple-Negative Breast Cancer Cell Invasiveness via Induction of Metalloproteinase Expression

(2015) Alicja M. Kmiecik et al.   PLoS One

Aberrant Liver Insulin Receptor Isoform A Expression Normalises with Remission of Type 2 Diabetes after Gastric Bypass Surgery

(2015) Vinko Besic et al.   PLoS One

Garlic extract attenuates brain mitochondrial dysfunction and cognitive deficit in obese-insulin resistant rats

(2014) Hiranya Pintana et al.   Applied Physiology Nutrition and Metabolism

Obesity-induced lysine acetylation increases cardiac fatty acid oxidation and impairs insulin signalling

(2014) Osama Abo Alrob et al.   CARDIOVASCULAR RESEARCH

Fibroblast growth factor 21 protects the heart from oxidative stress

(2014) Anna Planavila et al.   CARDIOVASCULAR RESEARCH

Novel Insights into the Cardio-Protective Effects of FGF21 in Lean and Obese Rat Hearts

(2014) Vanlata Patel et al.   PLoS One

Combined Vildagliptin and Metformin Exert Better Cardioprotection than Monotherapy against Ischemia-Reperfusion Injury in Obese-Insulin Resistant Rats

(2014) Nattayaporn Apaijai et al.   PLoS One

Effects of vildagliptin versus sitagliptin, on cardiac function, heart rate variability and mitochondrial function in obese insulin-resistant rats

(2013) Nattayaporn Apaijai et al.   BRITISH JOURNAL OF PHARMACOLOGY

Proteomic study on the protective mechanism of fibroblast growth factor 21 to ischemia–reperfusion injury

(2013) Wei-Tao Cong et al.   CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY

Dipeptidyl peptidase-4 inhibitor reduces infarct size and preserves cardiac function via mitochondrial protection in ischaemia–reperfusion rat heart

(2013) Kroekkiat Chinda et al.   Diabetes & Vascular Disease Research

High-Fat Feeding-Induced Hyperinsulinemia Increases Cardiac Glucose Uptake and Mitochondrial Function Despite Peripheral Insulin Resistance

(2013) Anisha A. Gupte et al.   ENDOCRINOLOGY

Mechanisms responsible for beneficial and adverse effects of rosiglitazone in a rat model of acute cardiac ischaemia-reperfusion

(2013) Siripong Palee et al.   EXPERIMENTAL PHYSIOLOGY

Heart energy metabolism impairment in Western-diet induced obese mice

(2013) Fabiana A. Neves et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Fibroblast growth factor 21 protects against cardiac hypertrophy in mice

(2013) A. Planavila et al.   Nature Communications

Cardioprotective Effects of Metformin and Vildagliptin in Adult Rats with Insulin Resistance Induced by a High-Fat Diet

(2012) Nattayaporn Apaijai et al.   ENDOCRINOLOGY

Cardioprotective effect of dipeptidyl peptidase-4 inhibitor during ischemia–reperfusion injury

(2012) Kroekkiat Chinda et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Inhibition of p38 MAPK During Ischemia, But Not Reperfusion, Effectively Attenuates Fatal Arrhythmia in Ischemia/Reperfusion Heart

(2012) Sirirat Surinkaew et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

Omentin, a novel adipocytokine inhibits TNF-induced vascular inflammation in human endothelial cells

(2011) Hideyuki Yamawaki et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Lack of Overt FGF21 Resistance in Two Mouse Models of Obesity and Insulin Resistance

(2011) Clarence Hale et al.   ENDOCRINOLOGY

PPARγ Agonist Improves Neuronal Insulin Receptor Function in Hippocampus and Brain Mitochondria Function in Rats with Insulin Resistance Induced by Long Term High-Fat Diets

(2011) Noppamas Pipatpiboon et al.   ENDOCRINOLOGY

Effects of high-fat diet on insulin receptor function in rat hippocampus and the level of neuronal corticosterone

(2011) Wasana Pratchayasakul et al.   LIFE SCIENCES

Granulocyte-colony stimulating factor attenuates mitochondrial dysfunction induced by oxidative stress in cardiac mitochondria

(2011) Savitree Thummasorn et al.   MITOCHONDRION

High-level expression and purification of soluble recombinant FGF21 protein by SUMO fusion in Escherichia coli

(2010) Huiyan Wang et al.   BMC BIOTECHNOLOGY

Animal research: Reporting in vivo experiments: The ARRIVE guidelines

(2010) Carol Kilkenny et al.   BRITISH JOURNAL OF PHARMACOLOGY

Obesity Is a Fibroblast Growth Factor 21 (FGF21)-Resistant State

(2010) f. M. Fisher et al.   DIABETES

Fibroblast growth factor 21 regulates energy metabolism by activating the AMPK–SIRT1–PGC-1α pathway

(2010) Mary D. L. Chau et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Effects of curcuminoid supplement on cardiac autonomic status in high-fat–induced obese rats

(2009) Anchalee Pongchaidecha et al.   NUTRITION

Validation of Volume-Pressure Recording Tail-Cuff Blood Pressure Measurements

(2008) M. Feng et al.   AMERICAN JOURNAL OF HYPERTENSION

Inhibition of Tumor Necrosis Factor α–Stimulated Monocyte Adhesion to Human Aortic Endothelial Cells by AMP-Activated Protein Kinase

(2008) Marie-Ann Ewart et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Perivascular adipose tissue-derived visfatin is a vascular smooth muscle cell growth factor: role of nicotinamide mononucleotide

(2008) Pei Wang et al.   CARDIOVASCULAR RESEARCH