The epigenome in Alzheimer’s disease: current state and approaches for a new path to gene discovery and understanding disease mechanism
出版年份 2016 全文链接
标题
The epigenome in Alzheimer’s disease: current state and approaches for a new path to gene discovery and understanding disease mechanism
作者
关键词
DNA methylation, Epigenomics, Chromatin, Alzheimer’s disease, Aging, Histone
出版物
ACTA NEUROPATHOLOGICA
Volume 132, Issue 4, Pages 503-514
出版商
Springer Nature
发表日期
2016-08-29
DOI
10.1007/s00401-016-1612-7
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- The Cellular Phase of Alzheimer’s Disease
- (2016) Bart De Strooper et al. CELL
- miR‐132 loss de‐represses ITPKB and aggravates amyloid and TAU pathology in Alzheimer's brain
- (2016) Evgenia Salta et al. EMBO Molecular Medicine
- The Aging Epigenome
- (2016) Lauren N. Booth et al. MOLECULAR CELL
- Lateral Thinking: How Histone Modifications Regulate Gene Expression
- (2016) Moyra Lawrence et al. TRENDS IN GENETICS
- Uncovering the Role of the Methylome in Dementia and Neurodegeneration
- (2016) Hans-Ulrich Klein et al. TRENDS IN MOLECULAR MEDICINE
- Genome-wide DNA methylation profiling in the superior temporal gyrus reveals epigenetic signatures associated with Alzheimer’s disease
- (2016) Corey T. Watson et al. Genome Medicine
- Epigenome-wide Association Studies and the Interpretation of Disease -Omics
- (2016) Ewan Birney et al. PLoS Genetics
- The cerebellum ages slowly according to the epigenetic clock
- (2015) Steve Horvath et al. Aging-US
- Epigenetic age of the pre-frontal cortex is associated with neuritic plaques, amyloid load, and Alzheimer’s disease related cognitive functioning
- (2015) Morgan E Levine et al. Aging-US
- Interindividual methylomic variation across blood, cortex, and cerebellum: implications for epigenetic studies of neurological and neuropsychiatric phenotypes
- (2015) Eilis Hannon et al. Epigenetics
- Trimethylation of Lys36 on H3 restricts gene expression change during aging and impacts life span
- (2015) Mintie Pu et al. GENES & DEVELOPMENT
- Association of DNA methylation in the brain with age in older persons is confounded by common neuropathologies
- (2015) Jingyun Yang et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Integrative analysis of 111 reference human epigenomes
- (2015) Anshul Kundaje et al. NATURE
- Conserved epigenomic signals in mice and humans reveal immune basis of Alzheimer’s disease
- (2015) Elizabeta Gjoneska et al. NATURE
- Epigenome editing by a CRISPR-Cas9-based acetyltransferase activates genes from promoters and enhancers
- (2015) Isaac B Hilton et al. NATURE BIOTECHNOLOGY
- The epigenetics of aging and neurodegeneration
- (2015) Roy Lardenoije et al. PROGRESS IN NEUROBIOLOGY
- A Werner syndrome stem cell model unveils heterochromatin alterations as a driver of human aging
- (2015) W. Zhang et al. SCIENCE
- Epigenomics of Alzheimer's disease
- (2015) David A. Bennett et al. Translational Research
- Genetic and epigenetic fine mapping of causal autoimmune disease variants
- (2014) Kyle Kai-How Farh et al. NATURE
- Methylomic profiling implicates cortical deregulation of ANK1 in Alzheimer's disease
- (2014) Katie Lunnon et al. NATURE NEUROSCIENCE
- Alzheimer's disease: early alterations in brain DNA methylation at ANK1, BIN1, RHBDF2 and other loci
- (2014) Philip L De Jager et al. NATURE NEUROSCIENCE
- Tau promotes neurodegeneration through global chromatin relaxation
- (2014) Bess Frost et al. NATURE NEUROSCIENCE
- Targeting histone-modifications in Alzheimer's disease. What is the evidence that this is a promising therapeutic avenue?
- (2014) Andre Fischer NEUROPHARMACOLOGY
- Transcriptional and epigenetic regulation of Hebbian and non-Hebbian plasticity
- (2014) Mikael C. Guzman-Karlsson et al. NEUROPHARMACOLOGY
- Alteration of the microRNA network during the progression of Alzheimer's disease
- (2013) Pierre Lau et al. EMBO Molecular Medicine
- A cell epigenotype specific model for the correction of brain cellular heterogeneity bias and its application to age, brain region and major depression
- (2013) Jerry Guintivano et al. Epigenetics
- Epigenome-wide association data implicate DNA methylation as an intermediary of genetic risk in rheumatoid arthritis
- (2013) Yun Liu et al. NATURE BIOTECHNOLOGY
- Senescent cells harbour features of the cancer epigenome
- (2013) Hazel A. Cruickshanks et al. NATURE CELL BIOLOGY
- Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease
- (2013) Jean-Charles Lambert et al. NATURE GENETICS
- Transposition of native chromatin for fast and sensitive epigenomic profiling of open chromatin, DNA-binding proteins and nucleosome position
- (2013) Jason D Buenrostro et al. NATURE METHODS
- Epigenetic programming and reprogramming during development
- (2013) Irene Cantone et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Epigenetics: A novel therapeutic approach for the treatment of Alzheimer's disease
- (2013) Lina Adwan et al. PHARMACOLOGY & THERAPEUTICS
- Global Epigenomic Reconfiguration During Mammalian Brain Development
- (2013) R. Lister et al. SCIENCE
- Chromatin Modifications as Determinants of Muscle Stem Cell Quiescence and Chronological Aging
- (2013) Ling Liu et al. Cell Reports
- DNA methylation age of human tissues and cell types
- (2013) Steve Horvath GENOME BIOLOGY
- DNA Methylation Signatures in Development and Aging of the Human Prefrontal Cortex
- (2012) Shusuke Numata et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Relation of neuropathology to cognition in persons without cognitive impairment
- (2012) David A. Bennett et al. ANNALS OF NEUROLOGY
- Cancer Genetics and Epigenetics: Two Sides of the Same Coin?
- (2012) Jueng Soo You et al. CANCER CELL
- Genome-wide Methylation Profiles Reveal Quantitative Views of Human Aging Rates
- (2012) Gregory Hannum et al. MOLECULAR CELL
- ChromHMM: automating chromatin-state discovery and characterization
- (2012) Jason Ernst et al. NATURE METHODS
- Functions of DNA methylation: islands, start sites, gene bodies and beyond
- (2012) Peter A. Jones NATURE REVIEWS GENETICS
- Regulation of chromatin by histone modifications
- (2011) Andrew J Bannister et al. CELL RESEARCH
- Evaluation of the Infinium Methylation 450K technology
- (2011) Sarah Dedeurwaerder et al. Epigenomics
- Interplay between microRNAs and the epigenetic machinery: An intricate network
- (2010) Marilena V. Iorio et al. Biochimica et Biophysica Acta-Gene Regulatory Mechanisms
- Charting histone modifications and the functional organization of mammalian genomes
- (2010) Vicky W. Zhou et al. NATURE REVIEWS GENETICS
- Developmental regulation and individual differences of neuronal H3K4me3 epigenomes in the prefrontal cortex
- (2010) I. Cheung et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Abundant Quantitative Trait Loci Exist for DNA Methylation and Gene Expression in Human Brain
- (2010) J. Raphael Gibbs et al. PLoS Genetics
- The Nuclear DNA Base 5-Hydroxymethylcytosine Is Present in Purkinje Neurons and the Brain
- (2009) S. Kriaucionis et al. SCIENCE
- Aging Mice Show a Decreasing Correlation of Gene Expression within Genetic Modules
- (2009) Lucinda K. Southworth et al. PLoS Genetics
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