Macrophage-microbe interaction: lessons learned from the pathogen Mycobacterium tuberculosis

Mycobacterium tuberculosis ESAT6 induces IFN-β gene expression in Macrophages via TLRs-mediated signaling

(2018) Ah-Ra Jang et al.   CYTOKINE

Type I interferons in tuberculosis: Foe and occasionally friend

(2018) Lúcia Moreira-Teixeira et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The SecA2 pathway of Mycobacterium tuberculosis exports effectors that work in concert to arrest phagosome and autophagosome maturation

(2018) Katelyn E. Zulauf et al.   PLoS Pathogens

Macrophage Heterogeneity in the Immunopathogenesis of Tuberculosis

(2018) Mohlopheni J. Marakalala et al.   Frontiers in Microbiology

Phenolic Glycolipid Facilitates Mycobacterial Escape from Microbicidal Tissue-Resident Macrophages

(2017) C.J. Cambier et al.   IMMUNITY

Overview of the IL-1 family in innate inflammation and acquired immunity

(2017) Charles A. Dinarello   IMMUNOLOGICAL REVIEWS

A Coronin 1–Dependent Decision Switch in Juvenile Mice Determines the Population of the Peripheral Naive T Cell Compartment

(2017) Mathias Jakob Lang et al.   JOURNAL OF IMMUNOLOGY

Mycobacterium tuberculosis : Rewiring host cell signaling to promote infection

(2017) Michael D. Stutz et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Identification of mycobacterial GarA as a substrate of protein kinase G from M. tuberculosis using a KESTREL-based proteome wide approach

(2017) Philipp Mueller et al.   JOURNAL OF MICROBIOLOGICAL METHODS

Survival of Mycobacterium tuberculosis and Mycobacterium bovis BCG in lysosomes in vivo

(2017) Varadharajan Sundaramurthy et al.   MICROBES AND INFECTION

Listeria monocytogenes: towards a complete picture of its physiology and pathogenesis

(2017) Lilliana Radoshevich et al.   NATURE REVIEWS MICROBIOLOGY

The mycobacterial phosphatase PtpA regulates the expression of host genes and promotes cell proliferation

(2017) Jing Wang et al.   Nature Communications

cGAS-STING-TBK1-IRF3/7 induced interferon-β contributes to the clearing of non tuberculous mycobacterial infection in mice

(2017) Nanthapon Ruangkiattikul et al.   Virulence

Mycobacterium tuberculosis Controls Phagosomal Acidification by Targeting CISH-Mediated Signaling

(2017) Christophe J. Queval et al.   Cell Reports

PknG senses amino acid availability to control metabolism and virulence of Mycobacterium tuberculosis

(2017) Barbara Rieck et al.   PLoS Pathogens

Purinergic Signaling: A Common Path in the Macrophage Response against Mycobacterium tuberculosis and Toxoplasma gondii

(2017) Laetitia Petit-Jentreau et al.   Frontiers in Cellular and Infection Microbiology

SOCS Proteins as Regulators of Inflammatory Responses Induced by Bacterial Infections: A Review

(2017) Skyla A. Duncan et al.   Frontiers in Microbiology

The Role of Interferons in Inflammation and Inflammasome Activation

(2017) Nataša Kopitar-Jerala   Frontiers in Immunology

Mycobacterium tuberculosis DosR Regulon Gene Rv2004c Encodes a Novel Antigen with Pro-inflammatory Functions and Potential Diagnostic Application for Detection of Latent Tuberculosis

(2017) Sankara Narayana Doddam et al.   Frontiers in Immunology

Type I Interferons in the Pathogenesis of Tuberculosis: Molecular Drivers and Immunological Consequences

(2017) Meg L. Donovan et al.   Frontiers in Immunology

Polyfunctional CD4+ T Cells As Targets for Tuberculosis Vaccination

(2017) Deborah A. Lewinsohn et al.   Frontiers in Immunology

Dendritic cells that phagocytose apoptotic macrophages loaded with mycobacterial antigens activate CD8 T cells via cross-presentation

(2017) Patricia Espinosa-Cueto et al.   PLoS One

The Immunology of CD1- and MR1-Restricted T Cells

(2016) Lucia Mori et al.   Annual Review of Immunology

Regulation of calcium and phosphoinositides at endoplasmic reticulum–membrane junctions

(2016) Eamonn J. Dickson et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

To Be or Not Be a (Functional) Antibody Against TB

(2016) Arturo Casadevall   CELL

A Functional Role for Antibodies in Tuberculosis

(2016) Lenette L. Lu et al.   CELL

Mycobacterial Acid Tolerance Enables Phagolysosomal Survival and Establishment of Tuberculous Infection In Vivo

(2016) Steven Levitte et al.   Cell Host & Microbe

Phosphatidylinositol 3‐phosphates—at the interface between cell signalling and membrane traffic

(2016) Andrea L Marat et al.   EMBO JOURNAL

Molecular Determinants in Phagocyte-Bacteria Interactions

(2016) Stefan H.E. Kaufmann et al.   IMMUNITY

The Type III Secretion System Effector SptP of Salmonella enterica Serovar Typhi

(2016) Rebecca Johnson et al.   JOURNAL OF BACTERIOLOGY

Innate immunity in tuberculosis: how the sensing of mycobacteria and tissue damage modulates macrophage death

(2016) Eduardo P. Amaral et al.   MICROBES AND INFECTION

EspC forms a filamentous structure in the cell envelope ofMycobacterium tuberculosisand impacts ESX-1 secretion

(2016) Ye Lou et al.   MOLECULAR MICROBIOLOGY

Mycobacterial WhiB6 Differentially Regulates ESX-1 and the Dos Regulon to Modulate Granuloma Formation and Virulence in Zebrafish

(2016) Zhenkang Chen et al.   Cell Reports

The Mechanism for Type I Interferon Induction by Mycobacterium tuberculosis is Bacterial Strain-Dependent

(2016) Kirsten E. Wiens et al.   PLoS Pathogens

Identification of a Transcription Factor That Regulates Host Cell Exit and Virulence of Mycobacterium tuberculosis

(2016) Lalitha Srinivasan et al.   PLoS Pathogens

Macrophage form, function, and phenotype in mycobacterial infection: lessons from tuberculosis and other diseases

(2016) Colleen M. McClean et al.   Pathogens and Disease

Mycobacteria-responsive sonic hedgehog signaling mediates programmed death-ligand 1- and prostaglandin E2-induced regulatory T cell expansion

(2016) Sahana Holla et al.   Scientific Reports

Bacterial Proteasomes

(2015) Jordan B. Jastrab et al.   Annual Review of Microbiology

The structure of phosphoinositide phosphatases: Insights into substrate specificity and catalysis

(2015) FoSheng Hsu et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

T cell subsets and their signature cytokines in autoimmune and inflammatory diseases

(2015) Itay Raphael et al.   CYTOKINE

Cytokine-induced macropinocytosis in macrophages is regulated by 14-3-3ζ through its interaction with serine-phosphorylated coronin 1

(2015) Somdeb BoseDasgupta et al.   FEBS Journal

CD1 and mycobacterial lipids activate human T cells

(2015) Ildiko Van Rhijn et al.   IMMUNOLOGICAL REVIEWS

Macrophage defense mechanisms against intracellular bacteria

(2015) Günter Weiss et al.   IMMUNOLOGICAL REVIEWS

MR1-restricted mucosal associated invariant T (MAIT) cells in the immune response toMycobacterium tuberculosis

(2015) Marielle C. Gold et al.   IMMUNOLOGICAL REVIEWS

Proteasomal Control of Cytokinin Synthesis Protects Mycobacterium tuberculosis against Nitric Oxide

(2015) Marie I. Samanovic et al.   MOLECULAR CELL

Impairment of immunity to Candida and Mycobacterium in humans with bi-allelic RORC mutations

(2015) S. Okada et al.   SCIENCE

Pathology and immune reactivity: understanding multidimensionality in pulmonary tuberculosis

(2015) Anca Dorhoi et al.   Seminars in Immunopathology

Naturally produced opsonizing antibodies restrict the survival ofMycobacterium tuberculosisin human macrophages by augmenting phagosome maturation

(2015) Shashi Kant Kumar et al.   Open Biology

A Redox Regulatory System Critical for Mycobacterial Survival in Macrophages and Biofilm Development

(2015) Kerstin A. Wolff et al.   PLoS Pathogens

Cytosolic Access of Mycobacterium tuberculosis: Critical Impact of Phagosomal Acidification Control and Demonstration of Occurrence In Vivo

(2015) Roxane Simeone et al.   PLoS Pathogens

Coronin 1 trimerization is essential to protect pathogenic mycobacteria within macrophages from lysosomal delivery

(2014) Somdeb BoseDasgupta et al.   FEBS LETTERS

Discrimination between Active and Latent Tuberculosis Based on Ratio of Antigen-Specific to Mitogen-Induced IP-10 Production

(2014) Yun Hee Jeong et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Identification of secreted virulence factors of Chromobacterium violaceum

(2014) Thiago Castro-Gomes et al.   JOURNAL OF MICROBIOLOGY

Innate immune sensing of nucleic acids from mycobacteria

(2014) Lívia Harumi Yamashiro et al.   MICROBES AND INFECTION

In search of a new paradigm for protective immunity to TB

(2014) Cláudio Nunes-Alves et al.   NATURE REVIEWS MICROBIOLOGY

Cell death and autophagy in tuberculosis

(2014) Andrew H. Moraco et al.   SEMINARS IN IMMUNOLOGY

The Copper-Responsive RicR Regulon Contributes to Mycobacterium tuberculosis Virulence

(2014) X. Shi et al.   mBio

Inflammatory Stimuli Reprogram Macrophage Phagocytosis to Macropinocytosis for the Rapid Elimination of Pathogens

(2014) Somdeb BoseDasgupta et al.   PLoS Pathogens

The complexity of Rab5 to Rab7 transition guarantees specificity of pathogen subversion mechanisms

(2014) Giovanna Mottola   Frontiers in Cellular and Infection Microbiology

Cell death paradigms in the pathogenesis of Mycobacterium tuberculosis infection

(2014) Dinesh Kumar Parandhaman et al.   Frontiers in Cellular and Infection Microbiology

Of macrophages and red blood cells; a complex love story

(2014) Djuna Z. de Back et al.   Frontiers in Physiology

Striking the Right Balance Determines TB or Not TB

(2014) Somdeb BoseDasgupta et al.   Frontiers in Immunology

Macrophage Cytokines: Involvement in Immunity and Infectious Diseases

(2014) Guillermo Arango Duque et al.   Frontiers in Immunology

Pathways of Antigen Processing

(2013) Janice S. Blum et al.   Annual Review of Immunology

Type I interferons induce autophagy in certain human cancer cell lines

(2013) Hana Schmeisser et al.   Autophagy

Pupylation as a signal for proteasomal degradation in bacteria

(2013) Frank Striebel et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Analysis of SecA2-dependent substrates inMycobacterium marinumidentifies protein kinase G (PknG) as a virulence effector

(2013) Aniek D. van der Woude et al.   CELLULAR MICROBIOLOGY

The Spleen in Local and Systemic Regulation of Immunity

(2013) Vincenzo Bronte et al.   IMMUNITY

Erythrophagocytosis in circulating blood of loggerhead turtlesCaretta caretta: The pitting of Heinz bodies

(2013) Maria Grazia Ruggiero et al.   Journal of Experimental Zoology Part A-Ecological Genetics and Physiology

Irgm1 (LRG-47), a Regulator of Cell-Autonomous Immunity, Does Not Localize to Mycobacterial or Listerial Phagosomes in IFN- -Induced Mouse Cells

(2013) H. M. Springer et al.   JOURNAL OF IMMUNOLOGY

Microenvironments in Tuberculous Granulomas Are Delineated by Distinct Populations of Macrophage Subsets and Expression of Nitric Oxide Synthase and Arginase Isoforms

(2013) J. T. Mattila et al.   JOURNAL OF IMMUNOLOGY

Role of Interleukin 6 in Innate Immunity to Mycobacterium tuberculosis Infection

(2013) Alejandra N. Martinez et al.   JOURNAL OF INFECTIOUS DISEASES

Epidemiology: A mortal foe

(2013) Tom Paulson   NATURE

The ubiquitin ligase parkin mediates resistance to intracellular pathogens

(2013) Paolo S. Manzanillo et al.   NATURE

Role of Phospholipids in Endocytosis, Phagocytosis, and Macropinocytosis

(2013) Michal Bohdanowicz et al.   PHYSIOLOGICAL REVIEWS

Secreted Acid Phosphatase (SapM) of Mycobacterium tuberculosis Is Indispensable for Arresting Phagosomal Maturation and Growth of the Pathogen in Guinea Pig Tissues

(2013) Rupangi Verma Puri et al.   PLoS One

Macrophages in tuberculosis: friend or foe

(2013) Evelyn Guirado et al.   Seminars in Immunopathology

The Granuloma in Tuberculosis: Dynamics of a Host–Pathogen Collusion

(2013) Stefan Ehlers et al.   Frontiers in Immunology

ESX-1 dependent impairment of autophagic flux byMycobacterium tuberculosisin human dendritic cells

(2012) Alessandra Romagnoli et al.   Autophagy

Extracellular M. tuberculosis DNA Targets Bacteria for Autophagy by Activating the Host DNA-Sensing Pathway

(2012) Robert O. Watson et al.   CELL

IFN-Inducible GTPases in Host Cell Defense

(2012) Bae-Hoon Kim et al.   Cell Host & Microbe

Subversion of Phagocytosis for Pathogen Survival

(2012) Helen Sarantis et al.   Cell Host & Microbe

Mycobacterium Tuberculosis Activates the DNA-Dependent Cytosolic Surveillance Pathway within Macrophages

(2012) Paolo S. Manzanillo et al.   Cell Host & Microbe

ESX-1-mediated translocation to the cytosol controls virulence of mycobacteria

(2012) Diane Houben et al.   CELLULAR MICROBIOLOGY

Dynamic Roles of Type I and Type II IFNs in Early Infection with Mycobacterium tuberculosis

(2012) L. Desvignes et al.   JOURNAL OF IMMUNOLOGY

Macrophage plasticity and polarization in tissue repair and remodelling

(2012) Alberto Mantovani et al.   JOURNAL OF PATHOLOGY

Composition of the type VII secretion system membrane complex

(2012) Edith N. G. Houben et al.   MOLECULAR MICROBIOLOGY

MR1 presents microbial vitamin B metabolites to MAIT cells

(2012) Lars Kjer-Nielsen et al.   NATURE

How nascent phagosomes mature to become phagolysosomes

(2012) Gregory D. Fairn et al.   TRENDS IN IMMUNOLOGY

Phagosomal Rupture by Mycobacterium tuberculosis Results in Toxicity and Host Cell Death

(2012) Roxane Simeone et al.   PLoS Pathogens

Escape from the Phagosome: The Explanation for MHC-I Processing of Mycobacterial Antigens?

(2012) Melanie J. Harriff et al.   Frontiers in Immunology

The Shigella flexneri Type Three Secretion System Effector IpgD Inhibits T Cell Migration by Manipulating Host Phosphoinositide Metabolism

(2011) Christoph Konradt et al.   Cell Host & Microbe

Interleukins, from 1 to 37, and interferon-γ: Receptors, functions, and roles in diseases

(2011) Mübeccel Akdis et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Macrophages and control of granulomatous inflammation in tuberculosis

(2011) J L Flynn et al.   Mucosal Immunology

Germline CYBB mutations that selectively affect macrophages in kindreds with X-linked predisposition to tuberculous mycobacterial disease

(2011) Jacinta Bustamante et al.   NATURE IMMUNOLOGY

IL-10 Blocks Phagosome Maturation inMycobacterium tuberculosis–Infected Human Macrophages

(2010) Seónadh O'Leary et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Genome-wide Analysis of the Host Intracellular Network that Regulates Survival of Mycobacterium tuberculosis

(2010) Dhiraj Kumar et al.   CELL

The Phosphoinositide Phosphatase SopB Manipulates Membrane Surface Charge and Trafficking of the Salmonella-Containing Vacuole

(2010) Malina A. Bakowski et al.   Cell Host & Microbe

Mycobacterial lipoprotein activates autophagy via TLR2/1/CD14 and a functional vitamin D receptor signalling

(2010) Dong-Min Shin et al.   CELLULAR MICROBIOLOGY

Caseation of human tuberculosis granulomas correlates with elevated host lipid metabolism

(2010) Mi-Jeong Kim et al.   EMBO Molecular Medicine

Regulation of autophagy by phosphatidylinositol 3-phosphate

(2010) Chloe Burman et al.   FEBS LETTERS

Regulation of antigen presentation by Mycobacterium tuberculosis: a role for Toll-like receptors

(2010) Clifford V. Harding et al.   NATURE REVIEWS MICROBIOLOGY

The Type I NADH Dehydrogenase of Mycobacterium tuberculosis Counters Phagosomal NOX2 Activity to Inhibit TNF-α-Mediated Host Cell Apoptosis

(2010) Jessica L. Miller et al.   PLoS Pathogens

Modulation of the Arginase Pathway in the Context of Microbial Pathogenesis: A Metabolic Enzyme Moonlighting as an Immune Modulator

(2010) Priyanka Das et al.   PLoS Pathogens

Cryptococcal Cell Morphology Affects Host Cell Interactions and Pathogenicity

(2010) Laura H. Okagaki et al.   PLoS Pathogens

Fungal Cell Gigantism during Mammalian Infection

(2010) Oscar Zaragoza et al.   PLoS Pathogens

Mycobacterial Subversion of Chemotherapeutic Reagents and Host Defense Tactics: Challenges in Tuberculosis Drug Development

(2009) Liem Nguyen et al.   Annual Review of Pharmacology and Toxicology

Protein Kinase G Is Required for Intrinsic Antibiotic Resistance in Mycobacteria

(2009) K. A. Wolff et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Toll-like receptors in control of immunological autophagy

(2009) M A Delgado et al.   CELL DEATH AND DIFFERENTIATION

Patterns of Pathogenesis: Discrimination of Pathogenic and Nonpathogenic Microbes by the Innate Immune System

(2009) Russell E. Vance et al.   Cell Host & Microbe

Salmonella- the ultimate insider.Salmonellavirulence factors that modulate intracellular survival

(2009) J. Antonio Ibarra et al.   CELLULAR MICROBIOLOGY

Salmonella takes control: effector-driven manipulation of the host

(2009) Emma J McGhie et al.   CURRENT OPINION IN MICROBIOLOGY

The role of cytokines in the initiation, expansion, and control of cellular immunity to tuberculosis

(2009) Andrea M. Cooper et al.   IMMUNOLOGICAL REVIEWS

Mycobacteria Exploit p38 Signaling To Affect CD1 Expression and Lipid Antigen Presentation by Human Dendritic Cells

(2009) M. C. Gagliardi et al.   INFECTION AND IMMUNITY

Differential expression of a virulence factor in pathogenic and non-pathogenic mycobacteria

(2009) Edith N. G. Houben et al.   MOLECULAR MICROBIOLOGY

Potential role for ESAT6 in dissemination ofM. tuberculosisvia human lung epithelial cells

(2009) Arvind G. Kinhikar et al.   MOLECULAR MICROBIOLOGY

Targeting of the GTPase Irgm1 to the phagosomal membrane via PtdIns(3,4)P2 and PtdIns(3,4,5)P3 promotes immunity to mycobacteria

(2009) Sangeeta Tiwari et al.   NATURE IMMUNOLOGY

Foamy macrophages and the progression of the human tuberculosis granuloma

(2009) David G Russell et al.   NATURE IMMUNOLOGY

Mycobacterium tuberculosis evades macrophage defenses by inhibiting plasma membrane repair

(2009) Maziar Divangahi et al.   NATURE IMMUNOLOGY

Phthiocerol Dimycocerosates of M. tuberculosis Participate in Macrophage Invasion by Inducing Changes in the Organization of Plasma Membrane Lipids

(2009) Catherine Astarie-Dequeker et al.   PLoS Pathogens

NOD2, RIP2 and IRF5 Play a Critical Role in the Type I Interferon Response to Mycobacterium tuberculosis

(2009) Amit K. Pandey et al.   PLoS Pathogens

Mycobacterium tuberculosis and the Macrophage: Maintaining a Balance

(2008) Jean Pieters   Cell Host & Microbe

Delay of phagosome maturation by a mycobacterial lipid is reversed by nitric oxide

(2008) Sofia Axelrod et al.   CELLULAR MICROBIOLOGY

Mannose-capped lipoarabinomannan- and prostaglandin E2-dependent expansion of regulatory T cells in humanMycobacterium tuberculosisinfection

(2008) Ankita Garg et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Living on the edge: inhibition of host cell apoptosis byMycobacterium tuberculosis

(2008) Volker Briken et al.   Future Microbiology

The Lupus-Related Lmb3 Locus Contains a Disease-Suppressing Coronin-1A Gene Mutation

(2008) M. Katarina Haraldsson et al.   IMMUNITY

Outsmarting the host: bacteria modulating the immune response

(2008) Matthew D. Woolard et al.   IMMUNOLOGIC RESEARCH

Burkholderia thailandensis as a Model System for the Study of the Virulence-Associated Type III Secretion System of Burkholderia pseudomallei

(2008) A. Haraga et al.   INFECTION AND IMMUNITY

Heme Oxygenase-1-derived Carbon Monoxide Induces theMycobacterium tuberculosisDormancy Regulon

(2008) Ashwani Kumar et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of glutamate metabolism by protein kinases in mycobacteria

(2008) Helen M. O'Hare et al.   MOLECULAR MICROBIOLOGY

Regulation of T cell survival through coronin-1–mediated generation of inositol-1,4,5-trisphosphate and calcium mobilization after T cell receptor triggering

(2008) Philipp Mueller et al.   NATURE IMMUNOLOGY

A critical function for CD200 in lung immune homeostasis and the severity of influenza infection

(2008) Robert J Snelgrove et al.   NATURE IMMUNOLOGY

The actin regulator coronin 1A is mutant in a thymic egress–deficient mouse strain and in a patient with severe combined immunodeficiency

(2008) Lawrence R Shiow et al.   NATURE IMMUNOLOGY

A membrane protein preserves intrabacterial pH in intraphagosomal Mycobacterium tuberculosis

(2008) Omar H Vandal et al.   NATURE MEDICINE

Ubiquitin-Like Protein Involved in the Proteasome Pathway of Mycobacterium tuberculosis

(2008) M. J. Pearce et al.   SCIENCE

RNA Interference in J774 Macrophages Reveals a Role for Coronin 1 in Mycobacterial Trafficking but Not in Actin-dependent Processes

(2007) Rajesh Jayachandran et al.   MOLECULAR BIOLOGY OF THE CELL