MR1-restricted mucosal associated invariant T (MAIT) cells in the immune response toMycobacterium tuberculosis

Evolution of nonclassical MHC-dependent invariant T cells

(2014) Eva-Stina Edholm et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Innate mucosal-associated invariant T (MAIT) cells are activated in inflammatory bowel diseases

(2014) N.-E. Serriari et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

CD8+MAIT cells infiltrate into the CNS and alterations in their blood frequencies correlate with IL-18 serum levels in multiple sclerosis

(2014) Anne Willing et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

MR1-restricted MAIT cells display ligand discrimination and pathogen selectivity through distinct T cell receptor usage

(2014) Marielle C. Gold et al.   JOURNAL OF EXPERIMENTAL MEDICINE

A molecular basis underpinning the T cell receptor heterogeneity of mucosal-associated invariant T cells

(2014) Sidonia B.G. Eckle et al.   JOURNAL OF EXPERIMENTAL MEDICINE

T-cell activation by transitory neo-antigens derived from distinct microbial pathways

(2014) Alexandra J. Corbett et al.   NATURE

In search of a new paradigm for protective immunity to TB

(2014) Cláudio Nunes-Alves et al.   NATURE REVIEWS MICROBIOLOGY

Human Lung Epithelial Cells Contain Mycobacterium tuberculosis in a Late Endosomal Vacuole and Are Efficiently Recognized by CD8+ T Cells

(2014) Melanie J. Harriff et al.   PLoS One

Acquisition of innate-like microbial reactivity in mucosal tissues during human fetal MAIT-cell development

(2014) Edwin Leeansyah et al.   Nature Communications

Toll-Like Receptor 8 Agonist and Bacteria Trigger Potent Activation of Innate Immune Cells in Human Liver

(2014) Juandy Jo et al.   PLoS Pathogens

Pathways of Antigen Processing

(2013) Janice S. Blum et al.   Annual Review of Immunology

TNF Dually Mediates Resistance and Susceptibility to Mycobacteria via Mitochondrial Reactive Oxygen Species

(2013) Francisco J. Roca et al.   CELL

CD161++CD8+T cells, including the MAIT cell subset, are specifically activated by IL-12+IL-18 in a TCR-independent manner

(2013) James E. Ussher et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Early clearance ofMycobacterium tuberculosis: a new frontier in prevention

(2013) Ayesha J. Verrall et al.   IMMUNOLOGY

Antigen-loaded MR1 tetramers define T cell receptor heterogeneity in mucosal-associated invariant T cells

(2013) Rangsima Reantragoon et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Double Positive Thymocytes Select Mucosal-Associated Invariant T Cells

(2013) N. Seach et al.   JOURNAL OF IMMUNOLOGY

MAIT Recognition of a Stimulatory Bacterial Antigen Bound to MR1

(2013) J. Lopez-Sagaseta et al.   JOURNAL OF IMMUNOLOGY

MAIT Cell Recognition of MR1 on Bacterially Infected and Uninfected Cells

(2013) Mary H. Young et al.   PLoS One

The molecular basis for Mucosal-Associated Invariant T cell recognition of MR1 proteins

(2013) J. Lopez-Sagaseta et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MAIT cells are critical for optimal mucosal immune responses during in vivo pulmonary bacterial infection

(2013) A. Meierovics et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Recognition of vitamin B metabolites by mucosal-associated invariant T cells

(2013) Onisha Patel et al.   Nature Communications

MAIT Cells Detect and Efficiently Lyse Bacterially-Infected Epithelial Cells

(2013) Lionel Le Bourhis et al.   PLoS Pathogens

Outbreak of Transient Conversions of the QuantiFERON-TB Gold In-Tube Test in Laboratory Health Care Worker Screenings

(2012) Caterina Zanetti et al.   Clinical and Vaccine Immunology

NKT and MAIT invariant TCRα sequences can be produced efficiently by VJ gene recombination

(2012) Hui Yee Greenaway et al.   IMMUNOBIOLOGY

Polyclonal Mucosa-Associated Invariant T Cells Have Unique Innate Functions in Bacterial Infection

(2012) Wei-Jen Chua et al.   INFECTION AND IMMUNITY

Structural insight into MR1-mediated recognition of the mucosal associated invariant T cell receptor

(2012) Rangsima Reantragoon et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Human thymic MR1-restricted MAIT cells are innate pathogen-reactive effectors that adapt following thymic egress

(2012) M C Gold et al.   Mucosal Immunology

Escape from the Phagosome: The Explanation for MHC-I Processing of Mycobacterial Antigens?

(2012) Melanie J. Harriff et al.   Frontiers in Immunology

Mucosal-associated invariant T cells promote inflammation and exacerbate disease in murine models of arthritis

(2011) Asako Chiba et al.   ARTHRITIS AND RHEUMATISM

CD161highCD8+T cells bear pathogenetic potential in multiple sclerosis

(2011) Viviana Annibali et al.   BRAIN

Mucosal-associated invariant T cells regulate Th1 response in multiple sclerosis

(2011) Yusei Miyazaki et al.   INTERNATIONAL IMMUNOLOGY

PLZF induces an intravascular surveillance program mediated by long-lived LFA-1–ICAM-1 interactions

(2011) Seddon Y. Thomas et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Genetic Control of Biosynthesis and Transport of Riboflavin and Flavin Nucleotides and Construction of Robust Biotechnological Producers

(2011) C. A. Abbas et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Role of innate cytokines in mycobacterial infection

(2011) A M Cooper et al.   Mucosal Immunology

Altered Development of NKT Cells, γδ T Cells, CD8 T Cells and NK Cells in a PLZF Deficient Patient

(2011) Maggie Eidson et al.   PLoS One

Positive selecting cell type determines the phenotype of MHC class Ib-restricted CD8+T cells

(2011) Hoonsik Cho et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Vitamin D Is Required for IFN- -Mediated Antimicrobial Activity of Human Macrophages

(2011) M. Fabri et al.   Science Translational Medicine

Human MAIT cells are xenobiotic-resistant, tissue-targeted, CD161hi IL-17-secreting T cells

(2010) M. Dusseaux et al.   BLOOD

Predictors of persistently positive Mycobacterium-tuberculosis-specific interferon-gamma responses in the serial testing of health care workers

(2010) Felix C Ringshausen et al.   BMC INFECTIOUS DISEASES

Antimicrobial activity of mucosal-associated invariant T cells

(2010) Lionel Le Bourhis et al.   NATURE IMMUNOLOGY

Conservation of mucosal associated invariant T (MAIT) cells and the MR1 restriction element in ruminants, and abundance of MAIT cells in spleen

(2010) Nick Goldfinch et al.   VETERINARY RESEARCH

Human Mucosal Associated Invariant T Cells Detect Bacterially Infected Cells

(2010) Marielle C. Gold et al.   PLOS BIOLOGY

Interferon-γ-Responsive Nonhematopoietic Cells Regulate the Immune Response to Mycobacterium tuberculosis

(2009) Ludovic Desvignes et al.   IMMUNITY

The Tec kinases Itk and Rlk regulate conventional versus innate T-cell development

(2009) Amanda L. Prince et al.   IMMUNOLOGICAL REVIEWS

MR1 antigen presentation to mucosal-associated invariant T cells was highly conserved in evolution

(2009) S. Huang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Epidemiological benefits of more-effective tuberculosis vaccines, drugs, and diagnostics

(2009) L. J. Abu-Raddad et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TCR-inducible PLZF transcription factor required for innate phenotype of a subset of    T cells with restricted TCR diversity

(2009) T. Kreslavsky et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Investigation of chromosome 17 candidate genes in susceptibility to TB in a South African population

(2009) Marlo Möller et al.   TUBERCULOSIS

Stepwise Development of MAIT Cells in Mouse and Human

(2009) Emmanuel Martin et al.   PLOS BIOLOGY

The Transcription Factor PLZF Directs the Effector Program of the NKT Cell Lineage

(2008) Adam K. Savage et al.   IMMUNITY

Early T-cell responses in tuberculosis immunity

(2008) Gary M. Winslow et al.   IMMUNOLOGICAL REVIEWS

Mycobacterium avium Genes MAV_5138 and MAV_3679 Are Transcriptional Regulators That Play a Role in Invasion of Epithelial Cells, in Part by Their Regulation of CipA, a Putative Surface Protein Interacting with Host Cell Signaling Pathways

(2008) M. J. Harriff et al.   JOURNAL OF BACTERIOLOGY

MR1 uses an endocytic pathway to activate mucosal-associated invariant T cells

(2008) Shouxiong Huang et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Tuberculosis and latent tuberculosis infection in close contacts of people with pulmonary tuberculosis in low-income and middle-income countries: a systematic review and meta-analysis

(2008) Janina Morrison et al.   LANCET INFECTIOUS DISEASES

Tumour necrosis factor antagonists: structure, function, and tuberculosis risks

(2008) Robert S Wallis   LANCET INFECTIOUS DISEASES

Internalization of a non-pathogenic mycobacteria by macropinocytosis in human alveolar epithelial A549 cells

(2008) Blanca Estela García-Pérez et al.   MICROBIAL PATHOGENESIS

The BTB–zinc finger transcriptional regulator PLZF controls the development of invariant natural killer T cell effector functions

(2008) Damian Kovalovsky et al.   NATURE IMMUNOLOGY

ESAT-6-specific CD4 T cell responses to aerosol Mycobacterium tuberculosis infection are initiated in the mediastinal lymph nodes

(2008) W. W. Reiley et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA