Isoliquiritigenin Induces Mitochondrial Dysfunction and Apoptosis by Inhibiting mitoNEET in a Reactive Oxygen Species-Dependent Manner in A375 Human Melanoma Cells

Antineoplastic activity of isoliquiritigenin, a chalcone compound, in androgen-independent human prostate cancer cells linked to G2/M cell cycle arrest and cell apoptosis

(2018) Biyan Zhang et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Isoliquiritigenin inhibits the proliferation of human renal carcinoma Caki cells through the ROS-mediated regulation of the Jak2/STAT3 pathway

(2017) Do-Hee Kim et al.   ONCOLOGY REPORTS

Differentiation-inducing and anti-proliferative activities of isoliquiritigenin and all-trans-retinoic acid on B16F0 melanoma cells: Mechanisms profiling by RNA-seq

(2016) Xiaoyu Chen et al.   GENE

Isololiolide, a carotenoid metabolite isolated from the brown alga Cystoseira tamariscifolia, is cytotoxic and able to induce apoptosis in hepatocarcinoma cells through caspase-3 activation, decreased Bcl-2 levels, increased p53 expression and PARP cleavage

(2016) Catarina Vizetto-Duarte et al.   PHYTOMEDICINE

Isoliquiritigenin Inhibits Proliferation and Induces Apoptosis via Alleviating Hypoxia and Reducing Glycolysis in Mouse Melanoma B16F10 Cells

(2016) Yanming Wang et al.   Recent Patents on Anti-Cancer Drug Discovery

Targeted Radionuclide Therapy of Melanoma

(2016) Abdullah Norain et al.   SEMINARS IN NUCLEAR MEDICINE

Calcium and mitochondria in the regulation of cell death

(2015) Sten Orrenius et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Structure–function analysis of NEET proteins uncovers their role as key regulators of iron and ROS homeostasis in health and disease

(2015) Sagi Tamir et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Are free radicals involved in thiol-based redox signaling?

(2015) Christine C. Winterbourn   FREE RADICAL BIOLOGY AND MEDICINE

Radiotherapy for cutaneous melanoma: current and future applications

(2015) Peter Gorayski et al.   Future Oncology

A Review: The Pharmacology of Isoliquiritigenin

(2015) Fu Peng et al.   PHYTOTHERAPY RESEARCH

Evidence of oxidative stress and mitochondrial respiratory chain dysfunction in an in vitro model of sepsis-induced kidney injury

(2014) C. Quoilin et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Granzyme B-induced mitochondrial ROS are required for apoptosis

(2014) G Jacquemin et al.   CELL DEATH AND DIFFERENTIATION

Isoliquiritigenin Induces Apoptosis and Inhibits Xenograft Tumor Growth of Human Lung Cancer Cells by Targeting Both Wild Type and L858R/T790M Mutant EGFR

(2014) Sung Keun Jung et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Isoliquiritigenin-induced effects on Nrf2 mediated antioxidant defence in the HL-60 cell monocytic differentiation

(2013) Hongmei Chen et al.   CELL BIOLOGY INTERNATIONAL

Wolfram Syndrome protein, Miner1, regulates sulphydryl redox status, the unfolded protein response, and Ca2+homeostasis

(2013) Sandra E. Wiley et al.   EMBO Molecular Medicine

Mitoneet mediates TNFα-induced necroptosis promoted by exposure to fructose and ethanol

(2013) Nataly Shulga et al.   JOURNAL OF CELL SCIENCE

NAF-1 and mitoNEET are central to human breast cancer proliferation by maintaining mitochondrial homeostasis and promoting tumor growth

(2013) Yang-Sung Sohn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Isoliquiritigenin treatment induces apoptosis by increasing intracellular ROS levels in HeLa cells

(2012) Xuan Yuan et al.   JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH

MitoNEET-driven alterations in adipocyte mitochondrial activity reveal a crucial adaptive process that preserves insulin sensitivity in obesity

(2012) Christine M Kusminski et al.   NATURE MEDICINE

Isoliquiritigenin-Induced Differentiation in Mouse Melanoma B16F0 Cell Line

(2012) Xiaoyu Chen et al.   Oxidative Medicine and Cellular Longevity

Facile transfer of [2Fe-2S] clusters from the diabetes drug target mitoNEET to an apo-acceptor protein

(2011) John A. Zuris et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Free radicals and antioxidants – quo vadis?

(2011) Barry Halliwell   TRENDS IN PHARMACOLOGICAL SCIENCES

Apoptogenic factors released from mitochondria

(2010) David L. Vaux   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Reactive oxygen species, cellular redox systems, and apoptosis

(2010) Magdalena L. Circu et al.   FREE RADICAL BIOLOGY AND MEDICINE

Tetrandrine induces apoptosis by activating reactive oxygen species and repressing Akt activity in human hepatocellular carcinoma

(2010) Chaoyang Liu et al.   INTERNATIONAL JOURNAL OF CANCER

The energetics of genome complexity

(2010) Nick Lane et al.   NATURE

The Role of Mitochondria in Apoptosis

(2009) Chunxin Wang et al.   Annual Review of Genetics

Isoliquiritigenin induces monocytic differentiation of HL-60 cells

(2008) Defang Li et al.   FREE RADICAL BIOLOGY AND MEDICINE

CISD1 codifies a mitochondrial protein upregulated by the CFTR channel

(2007) Guillermo L. Taminelli et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS