标题
Blood-based biomarkers for Alzheimer disease: mapping the road to the clinic
作者
关键词
-
出版物
Nature Reviews Neurology
Volume 14, Issue 11, Pages 639-652
出版商
Springer Nature America, Inc
发表日期
2018-10-08
DOI
10.1038/s41582-018-0079-7
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Increased Plasma Beta-Secretase 1 May Predict Conversion to Alzheimer’s Disease Dementia in Individuals With Mild Cognitive Impairment
- (2018) Yong Shen et al. BIOLOGICAL PSYCHIATRY
- Untangling Genetic Risk for Alzheimer’s Disease
- (2018) Anna A. Pimenova et al. BIOLOGICAL PSYCHIATRY
- The cholinergic system in the pathophysiology and treatment of Alzheimer’s disease
- (2018) Harald Hampel et al. BRAIN
- A Blood Test for Alzheimer’s Disease: Progress, Challenges, and Recommendations
- (2018) Steven J. Kiddle et al. JOURNAL OF ALZHEIMERS DISEASE
- Revolution of Alzheimer Precision Neurology. Passageway of Systems Biology and Neurophysiology
- (2018) Harald Hampel et al. JOURNAL OF ALZHEIMERS DISEASE
- Cognitive and neuroimaging features and brain β-amyloidosis in individuals at risk of Alzheimer's disease (INSIGHT-preAD): a longitudinal observational study
- (2018) Bruno Dubois et al. LANCET NEUROLOGY
- High performance plasma amyloid-β biomarkers for Alzheimer’s disease
- (2018) Akinori Nakamura et al. NATURE
- Sex differences in Alzheimer disease — the gateway to precision medicine
- (2018) Maria Teresa Ferretti et al. Nature Reviews Neurology
- Precision pharmacology for Alzheimer’s disease
- (2018) Harald Hampel et al. PHARMACOLOGICAL RESEARCH
- Validation of a Serum Screen for Alzheimer's Disease Across Assay Platforms, Species, and Tissues
- (2018) Sid E. O'Bryant et al. JOURNAL OF ALZHEIMERS DISEASE
- Diagnostic function of the neuroinflammatory biomarker YKL-40 in Alzheimer’s disease and other neurodegenerative diseases
- (2017) Filippo Baldacci et al. Expert Review of Proteomics
- Plasma Amyloid-β Levels, Cerebral Small Vessel Disease, and Cognition: The Rotterdam Study
- (2017) Saima Hilal et al. JOURNAL OF ALZHEIMERS DISEASE
- A 9-microRNA Signature in Serum Serves as a Noninvasive Biomarker in Early Diagnosis of Alzheimer’s Disease
- (2017) Rui Guo et al. JOURNAL OF ALZHEIMERS DISEASE
- Strategic roadmap for an early diagnosis of Alzheimer's disease based on biomarkers
- (2017) Giovanni B Frisoni et al. LANCET NEUROLOGY
- Bridging the translational innovation gap through good biomarker practice
- (2017) Alain J. van Gool et al. NATURE REVIEWS DRUG DISCOVERY
- Serum neurofilament light in familial Alzheimer disease
- (2017) Philip S.J. Weston et al. NEUROLOGY
- Blood-based NfL
- (2017) Oskar Hansson et al. NEUROLOGY
- Cerebrospinal fluid and blood biomarkers for neurodegenerative dementias: An update of the Consensus of the Task Force on Biological Markers in Psychiatry of the World Federation of Societies of Biological Psychiatry
- (2017) Piotr Lewczuk et al. WORLD JOURNAL OF BIOLOGICAL PSYCHIATRY
- Association of Plasma Total Tau Level With Cognitive Decline and Risk of Mild Cognitive Impairment or Dementia in the Mayo Clinic Study on Aging
- (2017) Michelle M. Mielke et al. JAMA Neurology
- Association of Plasma Neurofilament Light With Neurodegeneration in Patients With Alzheimer Disease
- (2017) Niklas Mattsson et al. JAMA Neurology
- 2016 Alzheimer's disease facts and figures
- (2016) Alzheimers & Dementia
- Validating Alzheimer's disease micro RNAs using next-generation sequencing
- (2016) Andreas Keller et al. Alzheimers & Dementia
- Genomic variants, genes, and pathways of Alzheimer's disease: An overview
- (2016) Adam C. Naj et al. AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS
- TDP-43 stage, mixed pathologies, and clinical Alzheimer’s-type dementia
- (2016) Bryan D. James et al. BRAIN
- Comparison of three analytical platforms for quantification of the neurofilament light chain in blood samples: ELISA, electrochemiluminescence immunoassay and Simoa
- (2016) Jens Kuhle et al. CLINICAL CHEMISTRY AND LABORATORY MEDICINE
- Synaptic degeneration and neurogranin in the pathophysiology of Alzheimer’s disease
- (2016) Simone Lista et al. Expert Review of Neurotherapeutics
- Association of Plasma Aβ40 Peptides, But Not Aβ42, with Coronary Artery Disease and Diabetes Mellitus
- (2016) Benjamin Roeben et al. JOURNAL OF ALZHEIMERS DISEASE
- Harnessing Cerebrospinal Fluid Biomarkers in Clinical Trials for Treating Alzheimer's and Parkinson's Diseases: Potential and Challenges
- (2016) Dana Kim et al. Journal of Clinical Neurology
- Alzheimer's disease
- (2016) Philip Scheltens et al. LANCET
- CSF and blood biomarkers for the diagnosis of Alzheimer's disease: a systematic review and meta-analysis
- (2016) Bob Olsson et al. LANCET NEUROLOGY
- A/T/N: An unbiased descriptive classification scheme for Alzheimer disease biomarkers
- (2016) Clifford R. Jack et al. NEUROLOGY
- Plasma tau in Alzheimer disease
- (2016) Niklas Mattsson et al. NEUROLOGY
- Serum neurofilament light chain protein is a measure of disease intensity in frontotemporal dementia
- (2016) Jonathan D. Rohrer et al. NEUROLOGY
- Biomarker Tests for Molecularly Targeted Therapies — The Key to Unlocking Precision Medicine
- (2016) Gary H. Lyman et al. NEW ENGLAND JOURNAL OF MEDICINE
- Integrative methods for analyzing big data in precision medicine
- (2016) Vladimir Gligorijević et al. PROTEOMICS
- Early role of vascular dysregulation on late-onset Alzheimer’s disease based on multifactorial data-driven analysis
- (2016) Y. Iturria-Medina et al. Nature Communications
- Synaptic degeneration and neurogranin in the pathophysiology of Alzheimer’s disease
- (2016) Simone Lista et al. Expert Review of Neurotherapeutics
- Plasma neurofilament light chain predicts progression in progressive supranuclear palsy
- (2016) Julio C. Rojas et al. Annals of Clinical and Translational Neurology
- Plasma Concentration of the Neurofilament Light Protein (NFL) is a Biomarker of CNS Injury in HIV Infection: A Cross-Sectional Study
- (2016) Magnus Gisslén et al. EBioMedicine
- Plasma β-amyloid in Alzheimer’s disease and vascular disease
- (2016) Shorena Janelidze et al. Scientific Reports
- Guidelines for the standardization of preanalytic variables for blood-based biomarker studies in Alzheimer's disease research
- (2015) Sid E. O'Bryant et al. Alzheimers & Dementia
- Explorative and targeted neuroproteomics in Alzheimer's disease
- (2015) Ann Brinkmalm et al. BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS
- Amyloid imaging for dementia in clinical practice
- (2015) John T. O’Brien et al. BMC Medicine
- Neuroinflammation in Alzheimer's disease
- (2015) Michael T Heneka et al. LANCET NEUROLOGY
- A global reference for human genetic variation
- (2015) Richard A. Gibbs et al. NATURE
- Understanding Biomarkers of Neurodegeneration: Ultrasensitive detection techniques pave the way for mechanistic understanding
- (2015) Kaj Blennow et al. NATURE MEDICINE
- Blood-Brain Barrier Breakdown in the Aging Human Hippocampus
- (2015) Axel Montagne et al. NEURON
- A New Initiative on Precision Medicine
- (2015) Francis S. Collins et al. NEW ENGLAND JOURNAL OF MEDICINE
- The Potential of Pathological Protein Fragmentation in Blood-Based Biomarker Development for Dementia – With Emphasis on Alzheimer’s Disease
- (2015) Dilek Inekci et al. Frontiers in Neurology
- Plasma Aβ but Not Tau is Related to Brain PiB Retention in Early Alzheimer’s Disease
- (2014) Kai-Yuan Tzen et al. ACS Chemical Neuroscience
- Plasma proteins predict conversion to dementia from prodromal disease
- (2014) Abdul Hye et al. Alzheimers & Dementia
- Preferences of older people for early diagnosis and disclosure of Alzheimer's disease (AD) before and after considering potential risks and benefits
- (2014) Stephanie M. Robinson et al. ARCHIVES OF GERONTOLOGY AND GERIATRICS
- Brain metabolic dysfunction at the core of Alzheimer's disease
- (2014) Suzanne M. de la Monte et al. BIOCHEMICAL PHARMACOLOGY
- The overlap between vascular disease and Alzheimer’s disease - lessons from pathology
- (2014) Johannes Attems et al. BMC Medicine
- Advances in the therapy of Alzheimer’s disease: targeting amyloid beta and tau and perspectives for the future
- (2014) Harald Hampel et al. Expert Review of Neurotherapeutics
- Paths to Alzheimer’s disease prevention: From modifiable risk factors to biomarker enrichment strategies
- (2014) Simone Lista et al. Journal of Nutrition Health & Aging
- Advancing research diagnostic criteria for Alzheimer's disease: the IWG-2 criteria
- (2014) Bruno Dubois et al. LANCET NEUROLOGY
- Plasma phospholipids identify antecedent memory impairment in older adults
- (2014) Mark Mapstone et al. NATURE MEDICINE
- The amyloid-β degradation pattern in plasma—A possible tool for clinical trials in Alzheimer's disease
- (2014) Josef Pannee et al. NEUROSCIENCE LETTERS
- Prevalence of mixed pathologies in the aging brain
- (2014) Jasmin Rahimi et al. Alzheimers Research & Therapy
- Non-Alzheimer neurodegenerative pathologies and their combinations are more frequent than commonly believed in the elderly brain: a community-based autopsy series
- (2013) Gabor G. Kovacs et al. ACTA NEUROPATHOLOGICA
- Designing drug trials for Alzheimer’s disease: What we have learned from the release of the phase III antibody trials: A report from the EU/US/CTAD Task Force
- (2013) Bruno Vellas et al. Alzheimers & Dementia
- The future of blood-based biomarkers for Alzheimer's disease
- (2013) Kim Henriksen et al. Alzheimers & Dementia
- CSF Aβ1-42 combined with neuroimaging biomarkers in the early detection, diagnosis and prediction of Alzheimer's disease
- (2013) Simone Lista et al. Alzheimers & Dementia
- Developing novel blood-based biomarkers for Alzheimer's disease
- (2013) Heather M. Snyder et al. Alzheimers & Dementia
- Perspective on future role of biological markers in clinical therapy trials of Alzheimer's disease: A long-range point of view beyond 2020
- (2013) Harald Hampel et al. BIOCHEMICAL PHARMACOLOGY
- Use of biomarkers and imaging to assess pathophysiology, mechanisms of action and target engagement
- (2013) Harald Hampel et al. Journal of Nutrition Health & Aging
- A blood-based predictor for neocortical Aβ burden in Alzheimer’s disease: results from the AIBL study
- (2013) S C Burnham et al. MOLECULAR PSYCHIATRY
- Moving towards early clinical trials for amyloid-targeted therapy in Alzheimer's disease
- (2013) Paul S. Aisen et al. NATURE REVIEWS DRUG DISCOVERY
- Plasma tau levels in Alzheimer's disease
- (2013) Henrik Zetterberg et al. Alzheimers Research & Therapy
- Biomarkers for Alzheimer's disease in plasma, serum and blood - conceptual and practical problems
- (2013) Douglas Galasko et al. Alzheimers Research & Therapy
- Multiplex biomarkers in blood
- (2013) Veer Gupta et al. Alzheimers Research & Therapy
- Amyloid PET in clinical practice: Its place in the multidimensional space of Alzheimer's disease
- (2013) Rik Vandenberghe et al. NeuroImage-Clinical
- From integrative disease modeling to predictive, preventive, personalized and participatory (P4) medicine
- (2013) Erfan Younesi et al. EPMA Journal
- Development of biomarkers to chart all Alzheimer’s disease stages: The royal road to cutting the therapeutic Gordian Knot
- (2012) Harald Hampel et al. Alzheimers & Dementia
- Blood-Based Protein Biomarkers for Diagnosis of Alzheimer Disease
- (2012) James D. Doecke ARCHIVES OF NEUROLOGY
- Challenges and opportunities for oncology biomarker discovery
- (2012) Avisek Deyati et al. DRUG DISCOVERY TODAY
- Characterization of plasma β-secretase (BACE1) activity and soluble amyloid precursor proteins as potential biomarkers for Alzheimer's disease
- (2012) Guoxin Wu et al. JOURNAL OF NEUROSCIENCE RESEARCH
- From inherited to sporadic AD—crossing the biomarker bridge
- (2012) Harald Hampel et al. Nature Reviews Neurology
- A personal view on systems medicine and the emergence of proactive P4 medicine: predictive, preventive, personalized and participatory
- (2012) Leroy Hood et al. New Biotechnology
- Blood and plasma-based proteomic biomarker research in Alzheimer's disease
- (2012) Simone Lista et al. PROGRESS IN NEUROBIOLOGY
- Biological and methodical challenges of blood-based proteomics in the field of neurological research
- (2012) Simone Lista et al. PROGRESS IN NEUROBIOLOGY
- The diagnosis of dementia due to Alzheimer’s disease: Recommendations from the National Institute on Aging-Alzheimer’s Association workgroups on diagnostic guidelines for Alzheimer's disease
- (2011) Guy M. McKhann et al. Alzheimers & Dementia
- Incidence of Post-Dural Puncture Headache in Research Volunteers
- (2011) Sérgio Monteiro de Almeida et al. HEADACHE
- Neurodegenerative disease biomarkers: Guideposts for disease prevention through early diagnosis and intervention
- (2011) John Q. Trojanowski et al. PROGRESS IN NEUROBIOLOGY
- The role of genetics for biomarker development in neurodegeneration
- (2011) Lars Bertram et al. PROGRESS IN NEUROBIOLOGY
- Biomarkers in clinical trials for neurodegenerative diseases: Regulatory perspectives and requirements
- (2011) Karl Broich et al. PROGRESS IN NEUROBIOLOGY
- Oncogenic microRNAs (OncomiRs) as a new class of cancer biomarkers
- (2010) Vladimir A. Krutovskikh et al. BIOESSAYS
- Blood-based biomarkers of Alzheimer’s disease: challenging but feasible
- (2010) Madhav Thambisetty et al. Biomarkers in Medicine
- A map of human genome variation from population-scale sequencing
- (2010) Richard M. Durbin et al. NATURE
- Biomarkers for Alzheimer's disease: academic, industry and regulatory perspectives
- (2010) Harald Hampel et al. NATURE REVIEWS DRUG DISCOVERY
- Cerebrospinal fluid and plasma biomarkers in Alzheimer disease
- (2010) Kaj Blennow et al. Nature Reviews Neurology
- Biomarkers for Alzheimer's disease therapeutic trials
- (2010) Harald Hampel et al. PROGRESS IN NEUROBIOLOGY
- Primary Care Visit Duration and Quality
- (2009) Lena M. Chen ARCHIVES OF INTERNAL MEDICINE
- Biological Marker Candidates of Alzheimer's Disease in Blood, Plasma, and Serum
- (2009) Philine Schneider et al. CNS Neuroscience & Therapeutics
- Amyloid β peptides in plasma in early diagnosis of Alzheimer's disease: A multicenter study with multiplexing
- (2009) P. Lewczuk et al. EXPERIMENTAL NEUROLOGY
- Bioinformatics for protein biomarker panel classification: what is needed to bring biomarker panels intoin vitrodiagnostics?
- (2009) Xavier Robin et al. Expert Review of Proteomics
- Deciphering complex mechanisms in neurodegenerative diseases: the advent of systems biology
- (2009) Farshid Noorbakhsh et al. TRENDS IN NEUROSCIENCES
- Plasma amyloid levels and the risk of AD in normal subjects in the Cardiovascular Health Study
- (2008) O. L. Lopez et al. NEUROLOGY
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