A Blood Test for Alzheimer’s Disease: Progress, Challenges, and Recommendations

High performance plasma amyloid-β biomarkers for Alzheimer’s disease

(2018) Akinori Nakamura et al.   NATURE

Characteristic Transformation of Blood Transcriptome in Alzheimer's Disease

(2018) Guangchun Han et al.   JOURNAL OF ALZHEIMERS DISEASE

A Blood Gene Expression Marker of Early Alzheimer's Disease

(2018) Katie Lunnon et al.   JOURNAL OF ALZHEIMERS DISEASE

Candidate Blood Proteome Markers of Alzheimer's Disease Onset and Progression: A Systematic Review and Replication Study

(2018) Steven J. Kiddle et al.   JOURNAL OF ALZHEIMERS DISEASE

High-Throughput Characterization of Blood Serum Proteomics of IBD Patients with Respect to Aging and Genetic Factors

(2017) Antonio F. Di Narzo et al.   PLoS Genetics

Genetic assessment of age-associated Alzheimer disease risk: Development and validation of a polygenic hazard score

(2017) Rahul S. Desikan et al.   PLOS MEDICINE

Proteome-Based Plasma Markers of Brain Amyloid-β Deposition in Non-Demented Older Individuals

(2017) Madhav Thambisetty et al.   JOURNAL OF ALZHEIMERS DISEASE

Trajectories of dementia-related cognitive decline in a large mental health records derived patient cohort

(2017) Elizabeth Baker et al.   PLoS One

Blood metabolite markers of preclinical Alzheimer's disease in two longitudinally followed cohorts of older individuals

(2016) Ramon Casanova et al.   Alzheimers & Dementia

Crowdsourced estimation of cognitive decline and resilience in Alzheimer's disease

(2016) Genevera I. Allen et al.   Alzheimers & Dementia

Genetic Risk as a Marker of Amyloid-β and Tau Burden in Cerebrospinal Fluid

(2016) Nicola Voyle et al.   JOURNAL OF ALZHEIMERS DISEASE

Pathway-Specific Polygenic Risk Scores as Predictors of Amyloid-β Deposition and Cognitive Function in a Sample at Increased Risk for Alzheimer’s Disease

(2016) Burcu F. Darst et al.   JOURNAL OF ALZHEIMERS DISEASE

Blood-Based Biomarker Candidates of Cerebral Amyloid Using PiB PET in Non-Demented Elderly

(2016) Sarah Westwood et al.   JOURNAL OF ALZHEIMERS DISEASE

CSF and blood biomarkers for the diagnosis of Alzheimer's disease: a systematic review and meta-analysis

(2016) Bob Olsson et al.   LANCET NEUROLOGY

The effect of increased genetic risk for Alzheimer's disease on hippocampal and amygdala volume

(2016) Michelle K. Lupton et al.   NEUROBIOLOGY OF AGING

Data Sharing

(2016) Dan L. Longo et al.   NEW ENGLAND JOURNAL OF MEDICINE

Cohort profile of the South London and Maudsley NHS Foundation Trust Biomedical Research Centre (SLaM BRC) Case Register: current status and recent enhancement of an Electronic Mental Health Record-derived data resource

(2016) Gayan Perera et al.   BMJ Open

Blood metabolite markers of neocortical amyloid-β burden: discovery and enrichment using candidate proteins

(2016) N Voyle et al.   Translational Psychiatry

Guidelines for the standardization of preanalytic variables for blood-based biomarker studies in Alzheimer's disease research

(2015) Sid E. O'Bryant et al.   Alzheimers & Dementia

Transparent Reporting of a multivariable prediction model for Individual Prognosis Or Diagnosis (TRIPOD): The TRIPOD Statement

(2015) Gary S. Collins et al.   ANNALS OF INTERNAL MEDICINE

Common polygenic variation enhances risk prediction for Alzheimer’s disease

(2015) Valentina Escott-Price et al.   BRAIN

A New Initiative on Precision Medicine

(2015) Francis S. Collins et al.   NEW ENGLAND JOURNAL OF MEDICINE

UK Biobank: An Open Access Resource for Identifying the Causes of a Wide Range of Complex Diseases of Middle and Old Age

(2015) Cathie Sudlow et al.   PLOS MEDICINE

Plasma protein biomarkers of Alzheimer’s disease endophenotypes in asymptomatic older twins: early cognitive decline and regional brain volumes

(2015) S J Kiddle et al.   Translational Psychiatry

Blood-Based Proteomic Biomarkers of Alzheimer’s Disease Pathology

(2015) Alison L. Baird et al.   Frontiers in Neurology

Circulating Proteomic Signatures of Chronological Age

(2014) Cristina Menni et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Plasma phospholipids identify antecedent memory impairment in older adults

(2014) Mark Mapstone et al.   NATURE MEDICINE

How to Make More Published Research True

(2014) John P. A. Ioannidis   PLOS MEDICINE

Combined Plasma Biomarkers for Diagnosing Mild Cognition Impairment and Alzheimer’s Disease

(2013) Ming-Jang Chiu et al.   ACS Chemical Neuroscience

Genome-wide association study of the rate of cognitive decline in Alzheimer's disease

(2013) Richard Sherva et al.   Alzheimers & Dementia

The Benefits of Using Genetic Information to Design Prevention Trials

(2013) Youna Hu et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease

(2013) Jean-Charles Lambert et al.   NATURE GENETICS

Blood-Based Protein Biomarkers for Diagnosis of Alzheimer Disease

(2012) James D. Doecke   ARCHIVES OF NEUROLOGY

Risk prediction models: II. External validation, model updating, and impact assessment

(2012) Karel G M Moons et al.   HEART

Multidimensional plasma protein separation technique for identification of potential Alzheimer’s disease plasma biomarkers: a pilot study

(2012) Andreas Wolfram Henkel et al.   JOURNAL OF NEURAL TRANSMISSION

The Association between a Polygenic Alzheimer Score and Cortical Thickness in Clinically Normal Subjects

(2011) Mert R. Sabuncu et al.   CEREBRAL CORTEX

Serum Levels of Pregnancy Zone Protein are Elevated in Presymptomatic Alzheimer’s Disease

(2011) Linda IJsselstijn et al.   JOURNAL OF PROTEOME RESEARCH

Genome-wide association with MRI atrophy measures as a quantitative trait locus for Alzheimer's disease

(2010) S J Furney et al.   MOLECULAR PSYCHIATRY

Five out of 16 plasma signaling proteins are enhanced in plasma of patients with mild cognitive impairment and Alzheimer's disease

(2009) Josef Marksteiner et al.   NEUROBIOLOGY OF AGING

Why Most Discovered True Associations Are Inflated

(2008) John P. A. Ioannidis   EPIDEMIOLOGY