Directly visualized glioblastoma-derived extracellular vesicles transfer RNA to microglia/macrophages in the brain

Glioblastoma-derived extracellular vesicles modify the phenotype of monocytic cells

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Visualization and tracking of tumour extracellular vesicle delivery and RNA translation using multiplexed reporters

(2015) Charles P. Lai et al.   Nature Communications

Cancer-Secreted miR-105 Destroys Vascular Endothelial Barriers to Promote Metastasis

(2014) Weiying Zhou et al.   CANCER CELL

A small noncoding RNA signature found in exosomes of GBM patient serum as a diagnostic tool

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Extracellular Vesicles Modulate the Glioblastoma Microenvironment via a Tumor Suppression Signaling Network Directed by miR-1

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(2013) Christian Ries   CELLULAR AND MOLECULAR LIFE SCIENCES

The Controversial Role of Microglia in Malignant Gliomas

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Molecular definition of the pro-tumorigenic phenotype of glioma-activated microglia

(2013) Aleksandra Ellert-Miklaszewska et al.   GLIA

Regulation of Cellular Processes by Interleukin-16 in Homeostasis and Cancer

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Heparin blocks transfer of extracellular vesicles between donor and recipient cells

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Review: Molecular mechanism of microglia stimulated glioblastoma invasion

(2013) Salvatore J. Coniglio et al.   MATRIX BIOLOGY

The Potential Role of miR-451 in Cancer Diagnosis, Prognosis, and Therapy

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Glioma microvesicles carry selectively packaged coding and non-coding RNAs which alter gene expression in recipient cells

(2013) Cheryl CY Li et al.   RNA Biology

Selective extracellular vesicle-mediated export of an overlapping set of microRNAs from multiple cell types

(2012) Jasenka Guduric-Fuchs et al.   BMC GENOMICS

Abstract 4920: Gene network models identify targets for mammary tumor normalization

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c-Myc Is a Universal Amplifier of Expressed Genes in Lymphocytes and Embryonic Stem Cells

(2012) Zuqin Nie et al.   CELL

Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET

(2012) Héctor Peinado et al.   NATURE MEDICINE

The molecular profile of microglia under the influence of glioma

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MicroRNAs are exported from malignant cells in customized particles

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Monocyte-Derived Cells of the Brain and Malignant Gliomas: The Double Face of Janus

(2012) Sergiy V. Kushchayev et al.   World Neurosurgery

Oncogenic extracellular vesicles in brain tumor progression

(2012) Esterina D’Asti et al.   Frontiers in Physiology

Anti-leukemic properties of IL-12, IL-23 and IL-27: Differences and similarities in the control of pediatric B acute lymphoblastic leukemia

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MicroRNA-451 regulates p38 MAPK signaling by targeting of Ywhaz and suppresses the mesangial hypertrophy in early diabetic nephropathy

(2011) Zheng Zhang et al.   FEBS LETTERS

Glioblastoma survival in the United States before and during the temozolomide era

(2011) Derek R. Johnson et al.   JOURNAL OF NEURO-ONCOLOGY

MicroRNAs are transported in plasma and delivered to recipient cells by high-density lipoproteins

(2011) Kasey C. Vickers et al.   NATURE CELL BIOLOGY

Characteristics of the Alternative Phenotype of Microglia/Macrophages and its Modulation in Experimental Gliomas

(2011) Konrad Gabrusiewicz et al.   PLoS One

Argonaute2 complexes carry a population of circulating microRNAs independent of vesicles in human plasma

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Tumour microvesicles contain retrotransposon elements and amplified oncogene sequences

(2011) Leonora Balaj et al.   Nature Communications

MiRNA-451 plays a role as tumor suppressor in human glioma cells

(2010) Yang Nan et al.   BRAIN RESEARCH

Integrated Genomic Analysis Identifies Clinically Relevant Subtypes of Glioblastoma Characterized by Abnormalities in PDGFRA, IDH1, EGFR, and NF1

(2010) Roel G.W. Verhaak et al.   CANCER CELL

Comprehensive modeling of microRNA targets predicts functional non-conserved and non-canonical sites

(2010) Doron Betel et al.   GENOME BIOLOGY

miR-21: a small multi-faceted RNA

(2008) Anna M. Krichevsky et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Microglial Dysfunction and Defective  -Amyloid Clearance Pathways in Aging Alzheimer's Disease Mice

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Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers

(2008) Johan Skog et al.   NATURE CELL BIOLOGY