ALTHEA Gold Libraries™: Antibody libraries for therapeutic antibody discovery

Progress and Challenges in the Design and Clinical Development of Antibodies for Cancer Therapy

(2018) Juan C. Almagro et al.   Frontiers in Immunology

Review of Biosimilar Trials and Data on Adalimumab in Rheumatoid Arthritis

(2018) Sizheng Zhao et al.   Current Rheumatology Reports

Biophysical properties of the clinical-stage antibody landscape

(2017) Tushar Jain et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Current progress in innovative engineered antibodies

(2017) William R. Strohl   Protein & Cell

Extending the half-life of a fab fragment through generation of a humanized anti-human serum albumin Fv domain: An investigation into the correlation between affinity and serum half-life

(2016) Ralph Adams et al.   mAbs

Phage display-derived human antibodies in clinical development and therapy

(2016) André Frenzel et al.   mAbs

Structural diversity in a human antibody germline library

(2016) Alexey Teplyakov et al.   mAbs

The ageing human B cell repertoire: a failure of selection?

(2015) D. K. Dunn-Walters   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Comprehensive optimization of a single-chain variable domain antibody fragment as a targeting ligand for a cytotoxic nanoparticle

(2014) Kathy Zhang et al.   mAbs

Second antibody modeling assessment (AMA-II)

(2014) Juan C. Almagro et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

A Structurally Distinct Human Mycoplasma Protein that Generically Blocks Antigen-Antibody Union

(2014) R. K. Grover et al.   SCIENCE

Stability engineering of the human antibody repertoire

(2013) Romain Rouet et al.   FEBS LETTERS

Two ScFv antibody libraries derived from identical VL-VH framework with different binding site designs display distinct binding profiles

(2013) T. Huovinen et al.   PROTEIN ENGINEERING DESIGN & SELECTION

Antigen-binding site anatomy and somatic mutations in antibodies that recognize different types of antigens

(2012) Gopalan Raghunathan et al.   JOURNAL OF MOLECULAR RECOGNITION

Structural basis for high selectivity of anti-CCL2 neutralizing antibody CNTO 888

(2012) Galina Obmolova et al.   MOLECULAR IMMUNOLOGY

Mechanisms of self-association of a human monoclonal antibody CNTO607

(2012) Deidra Bethea et al.   PROTEIN ENGINEERING DESIGN & SELECTION

Tolerogenic therapies in transplantation

(2012) Eugenia K. Page et al.   Frontiers in Immunology

High-Resolution Description of Antibody Heavy-Chain Repertoires in Humans

(2011) Ramy Arnaout et al.   PLoS One

De Novo Selection of High-Affinity Antibodies from Synthetic Fab Libraries Displayed on Phage as pIX Fusion Proteins

(2010) Lei Shi et al.   JOURNAL OF MOLECULAR BIOLOGY

Prediction of Aggregation Prone Regions of Therapeutic Proteins

(2010) Naresh Chennamsetty et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Precise determination of the diversity of a combinatorial antibody library gives insight into the human immunoglobulin repertoire

(2009) J. Glanville et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Synthetic Antibody Libraries Focused Towards Peptide Ligands

(2008) Christian W. Cobaugh et al.   JOURNAL OF MOLECULAR BIOLOGY

Thermodynamically Stable Aggregation-Resistant Antibody Domains through Directed Evolution

(2008) Kristoffer Famm et al.   JOURNAL OF MOLECULAR BIOLOGY