Novel pathways involved in cisplatin resistance identified by a proteomics approach in non-small-cell lung cancer cells

Proteomic identification of ERP29 as a key chemoresistant factor activated by the aggregating p53 mutant Arg282Trp

(2017) Y Zhang et al.   ONCOGENE

Mortalin overexpression predicts poor prognosis in early stage of non–small cell lung cancer

(2017) Jie Sun et al.   TUMOR BIOLOGY

Cathepsin L upregulation-induced EMT phenotype is associated with the acquisition of cisplatin or paclitaxel resistance in A549 cells

(2016) Mei-ling Han et al.   ACTA PHARMACOLOGICA SINICA

Stress Chaperone Mortalin Contributes to Epithelial-to-Mesenchymal Transition and Cancer Metastasis

(2016) Y. Na et al.   CANCER RESEARCH

Cisplatin in the modern era: The backbone of first-line chemotherapy for non-small cell lung cancer

(2016) D.A. Fennell et al.   CANCER TREATMENT REVIEWS

Biotin-targeted Pluronic ® P123/F127 mixed micelles delivering niclosamide: A repositioning strategy to treat drug-resistant lung cancer cells

(2016) Annapina Russo et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Proteomic characterization of peroxisome proliferator-activated receptor-γ (PPARγ) overexpressing or silenced colorectal cancer cells unveils a novel protein network associated with an aggressive phenotype

(2016) Maria Rita Milone et al.   Molecular Oncology

The ERK–ZEB1 pathway mediates epithelial–mesenchymal transition in pemetrexed resistant lung cancer cells with suppression by vinca alkaloids

(2016) L-Y Chiu et al.   ONCOGENE

Aldehyde dehydrogenase as a marker and functional mediator of metastasis in solid tumors

(2015) Mauricio Rodriguez-Torres et al.   CLINICAL & EXPERIMENTAL METASTASIS

The pyruvate dehydrogenase complex in cancer: An old metabolic gatekeeper regulated by new pathways and pharmacological agents

(2015) Elise Saunier et al.   INTERNATIONAL JOURNAL OF CANCER

Mitochondrial proteomics with siRNA knockdown to reveal ACAT1 and MDH2 in the development of doxorubicin-resistant uterine cancer

(2015) Yi-Wen Lo et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Regulation of VCP/p97 demonstrates the critical balance between cell death and epithelial-mesenchymal transition (EMT) downstream of ER stress

(2015) Parag P. Shah et al.   Oncotarget

EMT, CTCs and CSCs in tumor relapse and drug-resistance

(2015) Abhisek Mitra et al.   Oncotarget

Phosphorylation of lamins determine their structural properties and signaling functions

(2015) Elin Torvaldson et al.   Nucleus

Phosphorylation of lamins determine their structural properties and signaling functions

(2015) Elin Torvaldson et al.   Nucleus

The protein disulfide isomerases PDIA4 and PDIA6 mediate resistance to cisplatin-induced cell death in lung adenocarcinoma

(2014) G Tufo et al.   CELL DEATH AND DIFFERENTIATION

Pt-based drugs: the spotlight will be on proteins

(2014) O. Pinato et al.   Metallomics

Epithelial-Mesenchymal Transition Contributes to Docetaxel Resistance in Human Non-Small Cell Lung Cancer

(2014) Weiwei Shen et al.   ONCOLOGY RESEARCH

Inhibition of mortalin expression reverses cisplatin resistance and attenuates growth of ovarian cancer cells

(2013) Ling Yang et al.   CANCER LETTERS

Annexin A5 as a potential marker in tumors

(2013) Boya Peng et al.   CLINICA CHIMICA ACTA

Protein disulfide isomerase: a promising target for cancer therapy

(2013) Shili Xu et al.   DRUG DISCOVERY TODAY

ALDH7A1 expression is associated with recurrence in patients with surgically resected non-small-cell lung carcinoma

(2013) Nicholas J Giacalone et al.   Future Oncology

Evaluation and prognostic significance of ACAT1 as a marker of prostate cancer progression

(2013) Punit Saraon et al.   PROSTATE

Acquired resistance to zoledronic acid and the parallel acquisition of an aggressive phenotype are mediated by p38-MAP kinase activation in prostate cancer cells

(2013) M R Milone et al.   Cell Death & Disease

Acquisition of paclitaxel resistance is associated with a more aggressive and invasive phenotype in prostate cancer

(2012) John J. Kim et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

The enzymatic activity of human aldehyde dehydrogenases 1A2 and 2 (ALDH1A2 and ALDH2) is detected by Aldefluor, inhibited by diethylaminobenzaldehyde and has significant effects on cell proliferation and drug resistance

(2011) Jan S. Moreb et al.   CHEMICO-BIOLOGICAL INTERACTIONS

The AAA-ATPase VCP/p97 promotes 53BP1 recruitment by removing L3MBTL1 from DNA double-strand breaks

(2011) Klara Acs et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Molecular mechanisms of cisplatin resistance

(2011) L Galluzzi et al.   ONCOGENE

Critical Role of VCP/p97 in the Pathogenesis and Progression of Non-Small Cell Lung Carcinoma

(2011) Christopher W. Valle et al.   PLoS One

Lamin A/C Is a Risk Biomarker in Colorectal Cancer

(2008) Naomi D. Willis et al.   PLoS One