标题
Linear ubiquitination at a glance
作者
关键词
-
出版物
JOURNAL OF CELL SCIENCE
Volume 132, Issue 2, Pages jcs208512
出版商
The Company of Biologists
发表日期
2019-01-18
DOI
10.1242/jcs.208512
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Checkpoints in TNF-Induced Cell Death: Implications in Inflammation and Cancer
- (2018) Alessandro Annibaldi et al. TRENDS IN MOLECULAR MEDICINE
- TBK1 Suppresses RIPK1-Driven Apoptosis and Inflammation during Development and in Aging
- (2018) Daichao Xu et al. CELL
- OTULIN limits cell death and inflammation by deubiquitinating LUBAC
- (2018) Klaus Heger et al. NATURE
- LUBAC is essential for embryogenesis by preventing cell death and enabling haematopoiesis
- (2018) Nieves Peltzer et al. NATURE
- LUBAC prevents lethal dermatitis by inhibiting cell death induced by TNF, TRAIL and CD95L
- (2018) Lucia Taraborrelli et al. Nature Communications
- TBK1 and IKKε prevent TNF-induced cell death by RIPK1 phosphorylation
- (2018) Elodie Lafont et al. NATURE CELL BIOLOGY
- MK2 Phosphorylates RIPK1 to Prevent TNF-Induced Cell Death
- (2017) Isabel Jaco et al. MOLECULAR CELL
- p38MAPK/MK2-dependent phosphorylation controls cytotoxic RIPK1 signalling in inflammation and infection
- (2017) Manoj B. Menon et al. NATURE CELL BIOLOGY
- MK2 phosphorylation of RIPK1 regulates TNF-mediated cell death
- (2017) Yves Dondelinger et al. NATURE CELL BIOLOGY
- An Essential Role for SHARPIN in the Regulation of Caspase 1 Activity in Sepsis
- (2016) Madalina-Viviana Nastase et al. AMERICAN JOURNAL OF PATHOLOGY
- The Deubiquitinase OTULIN Is an Essential Negative Regulator of Inflammation and Autoimmunity
- (2016) Rune Busk Damgaard et al. CELL
- SPATA2 links CYLD to the TNF‐α receptor signaling complex and modulates the receptor signaling outcomes
- (2016) Sebastian A Wagner et al. EMBO JOURNAL
- SPATA2 promotes CYLD activity and regulates TNF‐induced NF‐κB signaling and cell death
- (2016) Lisa Schlicher et al. EMBO REPORTS
- Formation and removal of poly-ubiquitin chains in the regulation of tumor necrosis factor-induced gene activation and cell death
- (2016) Sebastian Kupka et al. FEBS Journal
- SHARPIN controls the development of regulatory T cells
- (2016) Vanessa Redecke et al. IMMUNOLOGY
- Molecular Determinants of Scaffold-induced Linear Ubiquitinylation of B Cell Lymphoma/Leukemia 10 (Bcl10) during T Cell Receptor and Oncogenic Caspase Recruitment Domain-containing Protein 11 (CARD11) Signaling
- (2016) Yong-Kang Yang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- LUBAC deficiency perturbs TLR3 signaling to cause immunodeficiency and autoinflammation
- (2016) Julia Zinngrebe et al. JOURNAL OF EXPERIMENTAL MEDICINE
- SPATA2 Links CYLD to LUBAC, Activates CYLD, and Controls LUBAC Signaling
- (2016) Paul R. Elliott et al. MOLECULAR CELL
- Necroptosis in development, inflammation and disease
- (2016) Ricardo Weinlich et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Biallelic hypomorphic mutations in a linear deubiquitinase define otulipenia, an early-onset autoinflammatory disease
- (2016) Qing Zhou et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The seventh zinc finger motif of A20 is required for the suppression of TNF-α-induced apoptosis
- (2015) Noritaka Yamaguchi et al. FEBS LETTERS
- Linear ubiquitination in immunity
- (2015) Yutaka Shimizu et al. IMMUNOLOGICAL REVIEWS
- Human HOIP and LUBAC deficiency underlies autoinflammation, immunodeficiency, amylopectinosis, and lymphangiectasia
- (2015) Bertrand Boisson et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Cutting Edge: SHARPIN Is Required for Optimal NLRP3 Inflammasome Activation
- (2015) Prajwal Gurung et al. JOURNAL OF IMMUNOLOGY
- The Inflammatory Caspases-1 and -11 Mediate the Pathogenesis of Dermatitis in Sharpin-Deficient Mice
- (2015) Todd Douglas et al. JOURNAL OF IMMUNOLOGY
- NF-κB-Independent Role of IKKα/IKKβ in Preventing RIPK1 Kinase-Dependent Apoptotic and Necroptotic Cell Death during TNF Signaling
- (2015) Yves Dondelinger et al. MOLECULAR CELL
- The ubiquitin-modifying enzyme A20 restricts ubiquitination of the kinase RIPK3 and protects cells from necroptosis
- (2015) Michio Onizawa et al. NATURE IMMUNOLOGY
- Structures of CYLD USP with Met1- or Lys63-linked diubiquitin reveal mechanisms for dual specificity
- (2015) Yusuke Sato et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Structures of CYLD USP with Met1- or Lys63-linked diubiquitin reveal mechanisms for dual specificity
- (2015) Yusuke Sato et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- LUBAC-Recruited CYLD and A20 Regulate Gene Activation and Cell Death by Exerting Opposing Effects on Linear Ubiquitin in Signaling Complexes
- (2015) Peter Draber et al. Cell Reports
- A catalytic-independent role for the LUBAC in NF- B activation upon antigen receptor engagement and in lymphoma cells
- (2014) S. M. Dubois et al. BLOOD
- A20: attractive without showing cleavage
- (2014) K. Verhelst et al. EMBO REPORTS
- The deubiquitinase activity of A20 is dispensable for NF- B signaling
- (2014) A. De et al. EMBO REPORTS
- Suppression of LUBAC-mediated linear ubiquitination by a specific interaction between LUBAC and the deubiquitinases CYLD and OTULIN
- (2014) Tsuyoshi Takiuchi et al. GENES TO CELLS
- The linear ubiquitin assembly complex (LUBAC) is essential for NLRP3 inflammasome activation
- (2014) Mary A. Rodgers et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Mechanism Underlying I B Kinase Activation Mediated by the Linear Ubiquitin Chain Assembly Complex
- (2014) H. Fujita et al. MOLECULAR AND CELLULAR BIOLOGY
- Binding of OTULIN to the PUB Domain of HOIP Controls NF-κB Signaling
- (2014) Veronique Schaeffer et al. MOLECULAR CELL
- Molecular Basis and Regulation of OTULIN-LUBAC Interaction
- (2014) Paul R. Elliott et al. MOLECULAR CELL
- Regulated necrosis: the expanding network of non-apoptotic cell death pathways
- (2014) Tom Vanden Berghe et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Screening of DUB activity and specificity by MALDI-TOF mass spectrometry
- (2014) Maria Stella Ritorto et al. Nature Communications
- Essential Role of the Linear Ubiquitin Chain Assembly Complex in Lymphoma Revealed by Rare Germline Polymorphisms
- (2014) Y. Yang et al. Cancer Discovery
- HOIP Deficiency Causes Embryonic Lethality by Aberrant TNFR1-Mediated Endothelial Cell Death
- (2014) Nieves Peltzer et al. Cell Reports
- Polyglucosan body myopathy caused by defective ubiquitin ligase RBCK1
- (2013) Johanna Nilsson et al. ANNALS OF NEUROLOGY
- OTU Deubiquitinases Reveal Mechanisms of Linkage Specificity and Enable Ubiquitin Chain Restriction Analysis
- (2013) Tycho E.T. Mevissen et al. CELL
- OTULIN Antagonizes LUBAC Signaling by Specifically Hydrolyzing Met1-Linked Polyubiquitin
- (2013) Kirstin Keusekotten et al. CELL
- Dimerization and Ubiquitin Mediated Recruitment of A20, a Complex Deubiquitinating Enzyme
- (2013) Timothy T. Lu et al. IMMUNITY
- Target Specificity of the E3 Ligase LUBAC for Ubiquitin and NEMO Relies on Different Minimal Requirements
- (2013) Judith J. Smit et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- OTULIN Restricts Met1-Linked Ubiquitination to Control Innate Immune Signaling
- (2013) Berthe Katrine Fiil et al. MOLECULAR CELL
- The linear ubiquitin-specific deubiquitinase gumby regulates angiogenesis
- (2013) Elena Rivkin et al. NATURE
- Structural basis for ligase-specific conjugation of linear ubiquitin chains by HOIP
- (2013) Benjamin Stieglitz et al. NATURE
- Activation of the canonical IKK complex by K63/M1-linked hybrid ubiquitin chains
- (2013) C. H. Emmerich et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A Genome-Wide siRNA Screen Reveals Positive and Negative Regulators of the NOD2 and NF- B Signaling Pathways
- (2013) N. Warner et al. Science Signaling
- Linear ubiquitination: a newly discovered regulator of cell signalling
- (2013) Eva Rieser et al. TRENDS IN BIOCHEMICAL SCIENCES
- Whole-genome DNA/RNA sequencing identifies truncating mutations in RBCK1 in a novel Mendelian disease with neuromuscular and cardiac involvement
- (2013) Kai Wang et al. Genome Medicine
- MAVS recruits multiple ubiquitin E3 ligases to activate antiviral signaling cascades
- (2013) Siqi Liu et al. eLife
- The Ubiquitin Code
- (2012) David Komander et al. Annual Review of Biochemistry
- Mixed Lineage Kinase Domain-like Protein Mediates Necrosis Signaling Downstream of RIP3 Kinase
- (2012) Liming Sun et al. CELL
- Linear Ubiquitination of NEMO Negatively Regulates the Interferon Antiviral Response through Disruption of the MAVS-TRAF3 Complex
- (2012) S. Mehdi Belgnaoui et al. Cell Host & Microbe
- A20 inhibits LUBAC-mediated NF-κB activation by binding linear polyubiquitin chains via its zinc finger 7
- (2012) Kelly Verhelst et al. EMBO JOURNAL
- Specific recognition of linear polyubiquitin by A20 zinc finger 7 is involved in NF-κB regulation
- (2012) Fuminori Tokunaga et al. EMBO JOURNAL
- The E3 ligase HOIP specifies linear ubiquitin chain assembly through its RING-IBR-RING domain and the unique LDD extension
- (2012) Judith J Smit et al. EMBO JOURNAL
- A non-canonical UBA–UBL interaction forms the linear-ubiquitin-chain assembly complex
- (2012) Hirokazu Yagi et al. EMBO REPORTS
- LUBAC synthesizes linear ubiquitin chains via a thioester intermediate
- (2012) Benjamin Stieglitz et al. EMBO REPORTS
- The Ubiquitin Ligase XIAP Recruits LUBAC for NOD2 Signaling in Inflammation and Innate Immunity
- (2012) Rune Busk Damgaard et al. MOLECULAR CELL
- Immunodeficiency, autoinflammation and amylopectinosis in humans with inherited HOIL-1 and LUBAC deficiency
- (2012) Bertrand Boisson et al. NATURE IMMUNOLOGY
- NF-κB Essential Modulator (NEMO) Interaction with Linear and Lys-63 Ubiquitin Chains Contributes to NF-κB Activation
- (2011) Kamyar Hadian et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- cIAPs Block Ripoptosome Formation, a RIP1/Caspase-8 Containing Intracellular Cell Death Complex Differentially Regulated by cFLIP Isoforms
- (2011) Maria Feoktistova et al. MOLECULAR CELL
- Linear Ubiquitin Assembly Complex Negatively Regulates RIG-I- and TRIM25-Mediated Type I Interferon Induction
- (2011) Kyung-Soo Inn et al. MOLECULAR CELL
- SHARPIN is a component of the NF-κB-activating linear ubiquitin chain assembly complex
- (2011) Fuminori Tokunaga et al. NATURE
- Catalytic activity of the caspase-8–FLIPL complex inhibits RIPK3-dependent necrosis
- (2011) Andrew Oberst et al. NATURE
- SHARPIN forms a linear ubiquitin ligase complex regulating NF-κB activity and apoptosis
- (2011) Fumiyo Ikeda et al. NATURE
- Linear ubiquitination prevents inflammation and regulates immune signalling
- (2011) Björn Gerlach et al. NATURE
- Caspase 8 inhibits programmed necrosis by processing CYLD
- (2011) Marie Anne O’Donnell et al. NATURE CELL BIOLOGY
- HOIL-1L Interacting Protein (HOIP) Is Essential for CD40 Signaling
- (2011) Bruce S. Hostager et al. PLoS One
- Systems analysis identifies an essential role for SHANK-associated RH domain-interacting protein (SHARPIN) in macrophage Toll-like receptor 2 (TLR2) responses
- (2011) D. E. Zak et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Specific recognition of linear ubiquitin chains by the Npl4 zinc finger (NZF) domain of the HOIL-1L subunit of the linear ubiquitin chain assembly complex
- (2011) Y. Sato et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- TNF-induced necroptosis in L929 cells is tightly regulated by multiple TNFR1 complex I and II members
- (2011) N Vanlangenakker et al. Cell Death & Disease
- c-IAP1 and UbcH5 promote K11-linked polyubiquitination of RIP1 in TNF signalling
- (2010) Jasmin N Dynek et al. EMBO JOURNAL
- Ubiquitin Binding to A20 ZnF4 Is Required for Modulation of NF-κB Signaling
- (2010) Ivan Bosanac et al. MOLECULAR CELL
- The Role of the Kinases RIP1 and RIP3 in TNF-Induced Necrosis
- (2010) P. Vandenabeele et al. Science Signaling
- Receptor Interacting Protein Kinase-3 Determines Cellular Necrotic Response to TNF-α
- (2009) Sudan He et al. CELL
- Specific Recognition of Linear Ubiquitin Chains by NEMO Is Important for NF-κB Activation
- (2009) Simin Rahighi et al. CELL
- NEMO specifically recognizes K63-linked poly-ubiquitin chains through a new bipartite ubiquitin-binding domain
- (2009) E Laplantine et al. EMBO JOURNAL
- The ubiquitin-editing enzyme A20 requires RNF11 to downregulate NF-κB signalling
- (2009) Noula Shembade et al. EMBO JOURNAL
- Molecular discrimination of structurally equivalent Lys 63-linked and linear polyubiquitin chains
- (2009) David Komander et al. EMBO REPORTS
- Recruitment of the Linear Ubiquitin Chain Assembly Complex Stabilizes the TNF-R1 Signaling Complex and Is Required for TNF-Mediated Gene Induction
- (2009) Tobias L. Haas et al. MOLECULAR CELL
- Involvement of linear polyubiquitylation of NEMO in NF-κB activation
- (2009) Fuminori Tokunaga et al. NATURE CELL BIOLOGY
- TNF-α Induces Two Distinct Caspase-8 Activation Pathways
- (2008) Lai Wang et al. CELL
- Identification of a Molecular Signaling Network that Regulates a Cellular Necrotic Cell Death Pathway
- (2008) Junichi Hitomi et al. CELL
- TWEAK-FN14 signaling induces lysosomal degradation of a cIAP1–TRAF2 complex to sensitize tumor cells to TNFα
- (2008) James E. Vince et al. JOURNAL OF CELL BIOLOGY
- The E3 ligase Itch negatively regulates inflammatory signaling pathways by controlling the function of the ubiquitin-editing enzyme A20
- (2008) Noula Shembade et al. NATURE IMMUNOLOGY
- Structure of the A20 OTU domain and mechanistic insights into deubiquitination
- (2007) David Komander et al. BIOCHEMICAL JOURNAL
- Molecular Basis for the Unique Deubiquitinating Activity of the NF-κB Inhibitor A20
- (2007) Su-Chang Lin et al. JOURNAL OF MOLECULAR BIOLOGY
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started