A catalytic-independent role for the LUBAC in NF- B activation upon antigen receptor engagement and in lymphoma cells

OTULIN Antagonizes LUBAC Signaling by Specifically Hydrolyzing Met1-Linked Polyubiquitin

(2013) Kirstin Keusekotten et al.   CELL

Defective immune responses in mice lacking LUBAC-mediated linear ubiquitination in B cells

(2013) Yoshiteru Sasaki et al.   EMBO JOURNAL

OTULIN Restricts Met1-Linked Ubiquitination to Control Innate Immune Signaling

(2013) Berthe Katrine Fiil et al.   MOLECULAR CELL

Activation of the canonical IKK complex by K63/M1-linked hybrid ubiquitin chains

(2013) C. H. Emmerich et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MAVS recruits multiple ubiquitin E3 ligases to activate antiviral signaling cascades

(2013) Siqi Liu et al.   eLife

Pathogenesis of Human B Cell Lymphomas

(2012) Arthur L. Shaffer et al.   Annual Review of Immunology

The Ubiquitin Ligase XIAP Recruits LUBAC for NOD2 Signaling in Inflammation and Innate Immunity

(2012) Rune Busk Damgaard et al.   MOLECULAR CELL

Immunodeficiency, autoinflammation and amylopectinosis in humans with inherited HOIL-1 and LUBAC deficiency

(2012) Bertrand Boisson et al.   NATURE IMMUNOLOGY

LUBAC regulates NF-κB activation upon genotoxic stress by promoting linear ubiquitination of NEMO

(2011) Jixiao Niu et al.   EMBO JOURNAL

Engineering and Structural Characterization of a Linear Polyubiquitin-Specific Antibody

(2011) Marissa L. Matsumoto et al.   JOURNAL OF MOLECULAR BIOLOGY

SHARPIN is a component of the NF-κB-activating linear ubiquitin chain assembly complex

(2011) Fuminori Tokunaga et al.   NATURE

SHARPIN forms a linear ubiquitin ligase complex regulating NF-κB activity and apoptosis

(2011) Fumiyo Ikeda et al.   NATURE

Linear ubiquitination prevents inflammation and regulates immune signalling

(2011) Björn Gerlach et al.   NATURE

Crosstalk in NF-κB signaling pathways

(2011) Andrea Oeckinghaus et al.   NATURE IMMUNOLOGY

The Emerging Role of Linear Ubiquitination in Cell Signaling

(2011) C. H. Emmerich et al.   Science Signaling

Aggressive Lymphomas

(2010) Georg Lenz et al.   NEW ENGLAND JOURNAL OF MEDICINE

Inhibition of MALT1 protease activity is selectively toxic for activated B cell–like diffuse large B cell lymphoma cells

(2009) Uta Ferch et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Recruitment of the Linear Ubiquitin Chain Assembly Complex Stabilizes the TNF-R1 Signaling Complex and Is Required for TNF-Mediated Gene Induction

(2009) Tobias L. Haas et al.   MOLECULAR CELL

Casein kinase 1α governs antigen-receptor-induced NF-κB activation and human lymphoma cell survival

(2009) Nicolas Bidère et al.   NATURE

Involvement of linear polyubiquitylation of NEMO in NF-κB activation

(2009) Fuminori Tokunaga et al.   NATURE CELL BIOLOGY

Essential role of MALT1 protease activity in activated B cell-like diffuse large B-cell lymphoma

(2009) S. Hailfinger et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The IKK Complex, a Central Regulator of NF- B Activation

(2009) A. Israel   Cold Spring Harbor Perspectives in Biology

NEMO recognition of ubiquitinated Bcl10 is required for T cell receptor-mediated NF- B activation

(2008) C.-J. Wu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA