An amphipathic helix of vinexin α is necessary for a substrate stiffness-dependent conformational change in vinculin

Vinexin family (SORBS) proteins regulate mechanotransduction in mesenchymal stem cells

(2018) Mito Kuroda et al.   Scientific Reports

Vinexin family (SORBS) proteins play different roles in stiffness-sensing and contractile force generation

(2017) Takafumi Ichikawa et al.   JOURNAL OF CELL SCIENCE

Vinculin promotes nuclear localization of TAZ to inhibit ECM stiffness-dependent differentiation into adipocytes

(2017) Mito Kuroda et al.   JOURNAL OF CELL SCIENCE

Vinculin association with actin cytoskeleton is necessary for stiffness-dependent regulation of vinculin behavior

(2017) Tomohiro Omachi et al.   PLoS One

Vinculin head–tail interaction defines multiple early mechanisms for cell substrate rigidity sensing

(2016) Zengzhen Liu et al.   Integrative Biology

High content image analysis of focal adhesion-dependent mechanosensitive stem cell differentiation

(2016) Andrew W. Holle et al.   Integrative Biology

Talin tension sensor reveals novel features of focal adhesion force transmission and mechanosensitivity

(2016) Abhishek Kumar et al.   JOURNAL OF CELL BIOLOGY

Integrin-mediated mechanotransduction

(2016) Zhiqi Sun et al.   JOURNAL OF CELL BIOLOGY

Mechanical regulation of a molecular clutch defines force transmission and transduction in response to matrix rigidity

(2016) Alberto Elosegui-Artola et al.   NATURE CELL BIOLOGY

Extracellular rigidity sensing by talin isoform-specific mechanical linkages

(2015) Katharina Austen et al.   NATURE CELL BIOLOGY

Force-dependent vinculin binding to talin in live cells: a crucial step in anchoring the actin cytoskeleton to focal adhesions

(2014) Hiroaki Hirata et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Force Engages Vinculin and Promotes Tumor Progression by Enhancing PI3K Activation of Phosphatidylinositol (3,4,5)-Triphosphate

(2014) Matthew G. Rubashkin et al.   CANCER RESEARCH

The role of the interaction of the vinculin proline-rich linker region with vinexin   in sensing the stiffness of the extracellular matrix

(2014) H. Yamashita et al.   JOURNAL OF CELL SCIENCE

Actomyosin-dependent formation of the mechanosensitive talin–vinculin complex reinforces actin anchoring

(2014) Corina Ciobanasu et al.   Nature Communications

Mechanical activation of vinculin binding to talin locks talin in an unfolded conformation

(2014) Mingxi Yao et al.   Scientific Reports

Vinculin Regulates the Recruitment and Release of Core Focal Adhesion Proteins in a Force-Dependent Manner

(2013) Alex Carisey et al.   CURRENT BIOLOGY

Site-specific Inhibitory Mechanism for Amyloid β42 Aggregation by Catechol-type Flavonoids Targeting the Lys Residues

(2013) Mizuho Sato et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Vinculin–actin interaction couples actin retrograde flow to focal adhesions, but is dispensable for focal adhesion growth

(2013) Ingo Thievessen et al.   JOURNAL OF CELL BIOLOGY

The Interaction of Vinculin with Actin

(2013) Javad Golji et al.   PLoS Computational Biology

α-Catenin Uses a Novel Mechanism to Activate Vinculin

(2012) Xiao Peng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Crucial role of vinexin for keratinocyte migration in vitro and epidermal wound healing in vivo

(2010) Noriyuki Kioka et al.   EXPERIMENTAL CELL RESEARCH

Matrix Crosslinking Forces Tumor Progression by Enhancing Integrin Signaling

(2009) Kandice R. Levental et al.   CELL

Cell-Cycle Control by Physiological Matrix Elasticity and In Vivo Tissue Stiffening

(2009) Eric A. Klein et al.   CURRENT BIOLOGY

Matrix density-induced mechanoregulation of breast cell phenotype, signaling and gene expression through a FAK–ERK linkage

(2009) P P Provenzano et al.   ONCOGENE

Stretching Single Talin Rod Molecules Activates Vinculin Binding

(2009) A. del Rio et al.   SCIENCE