标题
PI3Kinases in Diabetes Mellitus and Its Related Complications
作者
关键词
-
出版物
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Volume 19, Issue 12, Pages 4098
出版商
MDPI AG
发表日期
2018-12-18
DOI
10.3390/ijms19124098
参考文献
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注意：仅列出部分参考文献，下载原文获取全部文献信息。- Astilbin inhibits high glucose-induced autophagy and apoptosis through the PI3K/Akt pathway in human proximal tubular epithelial cells
- (2018) Fang Chen et al. BIOMEDICINE & PHARMACOTHERAPY
- Type 1 Diabetes in Parents and Risk of Attention Deficit/Hyperactivity Disorder in Offspring: A Population-Based Study in Sweden
- (2018) Jianguang Ji et al. DIABETES CARE
- Risk of Type 2 Diabetes in Adolescents and Young Adults With Attention-Deficit/Hyperactivity Disorder
- (2018) Mu-Hong Chen et al. JOURNAL OF CLINICAL PSYCHIATRY
- TAPP Adaptors Control B Cell Metabolism by Modulating the Phosphatidylinositol 3-Kinase Signaling Pathway: A Novel Regulatory Circuit Preventing Autoimmunity
- (2018) Nipun Jayachandran et al. JOURNAL OF IMMUNOLOGY
- Inhibition of theα-Subunit of Phosphoinositide 3-Kinase in Heart Increases Late Sodium Current and Is Arrhythmogenic
- (2018) Tao Yang et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- Obesity and type 2 diabetes mellitus drive immune dysfunction, infection development, and sepsis mortality
- (2018) Lynn M. Frydrych et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Dysregulation of PI3K-Akt-mTOR pathway in brain of streptozotocin-induced type 2 diabetes mellitus in Wistar rats
- (2018) Siresha Bathina et al. Lipids in Health and Disease
- Spotlight on copanlisib and its potential in the treatment of relapsed/refractory follicular lymphoma: evidence to date
- (2018) Felix Mensah et al. OncoTargets and Therapy
- MicroRNA 375 modulates hyperglycemia-induced enteric glial cell apoptosis and Diabetes-induced gastrointestinal dysfunction by targeting Pdk1 and repressing PI3K/Akt pathway
- (2018) Yan Chen et al. Scientific Reports
- Recent advances in the use of PI3K inhibitors for glioblastoma multiforme: current preclinical and clinical development
- (2017) Hua-fu Zhao et al. Molecular Cancer
- Adiponectin Attenuates Streptozotocin-Induced Tau Hyperphosphorylation and Cognitive Deficits by Rescuing PI3K/Akt/GSK-3β Pathway
- (2017) Zhi-Peng Xu et al. NEUROCHEMICAL RESEARCH
- La inhibición de la PI3Kγ protege contra la miocardiopatía diabética en ratones
- (2017) Angelo Maffei et al. REVISTA ESPANOLA DE CARDIOLOGIA
- Vps34 PI 3-kinase inactivation enhances insulin sensitivity through reprogramming of mitochondrial metabolism
- (2017) Benoit Bilanges et al. Nature Communications
- VEGF-B promotes recovery of corneal innervations and trophic functions in diabetic mice
- (2017) Guohu Di et al. Scientific Reports
- Role of T Lymphocytes in Type 2 Diabetes and Diabetes-Associated Inflammation
- (2017) Chang Xia et al. Journal of Diabetes Research
- Immunometabolic Regulations Mediated by Coinhibitory Receptors and Their Impact on T Cell Immune Responses
- (2017) Nikolaos Patsoukis et al. Frontiers in Immunology
- The use of 18F-Fluoro-deoxy-glucose positron emission tomography (18F-FDG PET) as a non-invasive pharmacodynamic biomarker to determine the minimally pharmacologically active dose of AZD8835, a novel PI3Kα inhibitor
- (2017) Juliana Maynard et al. PLoS One
- First-in-human phase I study of copanlisib (BAY 80-6946), an intravenous pan-class I phosphatidylinositol 3-kinase inhibitor, in patients with advanced solid tumors and non-Hodgkin's lymphomas
- (2016) A. Patnaik et al. ANNALS OF ONCOLOGY
- Calycosin ameliorates diabetes-induced cognitive impairments in rats by reducing oxidative stress via the PI3K/Akt/GSK-3β signaling pathway
- (2016) Xiang Wang et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Selective Insulin Resistance and the Development of Cardiovascular Diseases in Diabetes: The 2015 Edwin Bierman Award Lecture
- (2016) George L. King et al. DIABETES
- Activation of PPAR-γ reduces HPA axis activity in diabetic rats by up-regulating PI3K expression
- (2016) Rafael Carvalho Torres et al. EXPERIMENTAL AND MOLECULAR PATHOLOGY
- The class I phosphoinositide 3-kinases α and β control antiphospholipid antibodies-induced platelet activation
- (2016) Pierre-Alexandre Laurent et al. THROMBOSIS AND HAEMOSTASIS
- The use of 18F-fluorodeoxyglucose positron emission tomography (18F-FDG PET) as a pathway-specific biomarker with AZD8186, a PI3Kβ/δ inhibitor
- (2016) Juliana Maynard et al. EJNMMI Research
- PI3 kinases p110 α and PI3K-C2 β negatively regulate cAMP via PDE3/8 to control insulin secretion in mouse and human islets
- (2016) Jelena Kolic et al. Molecular Metabolism
- Electroacupuncture with high frequency at acupoint ST-36 induces regeneration of lost enteric neurons in diabetic rats via GDNF and PI3K/AKT signal pathway
- (2015) Fan Du et al. AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY
- Lack of kinase-independent activity of PI3K in locus coeruleus induces ADHD symptoms through increased CREB signaling
- (2015) I. D'Andrea et al. EMBO Molecular Medicine
- Exploration of efficacy and bleeding with combined phosphoinositide 3-kinase β inhibition and aspirin in man
- (2015) S. Nylander et al. JOURNAL OF THROMBOSIS AND HAEMOSTASIS
- PI3K-C2γ is a Rab5 effector selectively controlling endosomal Akt2 activation downstream of insulin signalling
- (2015) Laura Braccini et al. Nature Communications
- Phosphoinositide 3-Kinases p110α and p110β Have Differential Roles in Insulin-Like Growth Factor-1–Mediated Akt Phosphorylation and Platelet Priming
- (2014) Thomas A. Blair et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Diabetic cardiomyopathy: Mechanisms and new treatment strategies targeting antioxidant signaling pathways
- (2014) Karina Huynh et al. PHARMACOLOGY & THERAPEUTICS
- Insulin receptor substrate-2 is expressed in kidney epithelium and up-regulated in diabetic nephropathy
- (2013) Michelle B. Hookham et al. FEBS Journal
- Genome-wide meta-analysis of genetic susceptible genes for Type 2 Diabetes
- (2012) Paul J Hale et al. BMC Systems Biology
- Electrical Stimuli Release ATP to Increase GLUT4 Translocation and Glucose Uptake via PI3K -Akt-AS160 in Skeletal Muscle Cells
- (2012) C. Osorio-Fuentealba et al. DIABETES
- Human target validation of phosphoinositide 3-kinase (PI3K)β: effects on platelets and insulin sensitivity, using AZD6482 a novel PI3Kβ inhibitor
- (2012) S. NYLANDER et al. JOURNAL OF THROMBOSIS AND HAEMOSTASIS
- PI3Kγ inhibition reduces blood pressure by a vasorelaxant Akt/L-type calcium channel mechanism
- (2011) Daniela Carnevale et al. CARDIOVASCULAR RESEARCH
- Deficient brain insulin signalling pathway in Alzheimer's disease and diabetes
- (2011) Ying Liu et al. JOURNAL OF PATHOLOGY
- Integrating Cardiac PIP3 and cAMP Signaling through a PKA Anchoring Function of p110γ
- (2011) Alessia Perino et al. MOLECULAR CELL
- Deletion of the p110 isoform of phosphoinositide 3-kinase in platelets reveals its central role in Akt activation and thrombus formation in vitro and in vivo
- (2010) V. Martin et al. BLOOD
- Insulin Signaling to the Glomerular Podocyte Is Critical for Normal Kidney Function
- (2010) Gavin I. Welsh et al. Cell Metabolism
- Loss of Cardiac Phosphoinositide 3-Kinase p110α Results in Contractile Dysfunction
- (2009) Zhongju Lu et al. CIRCULATION
- Signaling cascade of insulin-induced stimulation of l-dopa uptake in renal proximal tubule cells
- (2008) Andrea Carranza et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- Genetic and Pharmacological Targeting of Phosphoinositide 3-Kinase-γ Reduces Atherosclerosis and Favors Plaque Stability by Modulating Inflammatory Processes
- (2008) Anne Fougerat et al. CIRCULATION
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