标题
Dendrimers Show Promise for siRNA and microRNA Therapeutics
作者
关键词
-
出版物
Pharmaceutics
Volume 10, Issue 3, Pages 126
出版商
MDPI AG
发表日期
2018-08-09
DOI
10.3390/pharmaceutics10030126
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- MicroRNA therapeutics: towards a new era for the management of cancer and other diseases
- (2017) Rajesha Rupaimoole et al. NATURE REVIEWS DRUG DISCOVERY
- The Race of 10 Synthetic RNAi-Based Drugs to the Pharmaceutical Market
- (2017) Ricardo Titze-de-Almeida et al. PHARMACEUTICAL RESEARCH
- Early Insights from Commercialization of Gene Therapies in Europe
- (2017) Nicolas Touchot et al. Genes
- Therapeutic miRNA and siRNA: Moving from Bench to Clinic as Next Generation Medicine
- (2017) Chiranjib Chakraborty et al. Molecular Therapy-Nucleic Acids
- Identification of Dormancy-Associated MicroRNAs for the Design of Osteosarcoma-Targeted Dendritic Polyglycerol Nanopolyplexes
- (2016) Galia Tiram et al. ACS Nano
- Modular degradable dendrimers enable small RNAs to extend survival in an aggressive liver cancer model
- (2016) Kejin Zhou et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Mastering Dendrimer Self-Assembly for Efficient siRNA Delivery: From Conceptual Design to In Vivo Efficient Gene Silencing
- (2016) Chao Chen et al. Small
- Chondroitin sulfate-functionalized polyamidoamine-mediated miR-34a delivery for inhibiting the proliferation and migration of pancreatic cancer
- (2016) Yan Duan et al. RSC Advances
- Recent progress in microRNA delivery for cancer therapy by non-viral synthetic vectors
- (2015) Huiyuan Wang et al. ADVANCED DRUG DELIVERY REVIEWS
- Preclinical and clinical development of siRNA-based therapeutics
- (2015) Gulnihal Ozcan et al. ADVANCED DRUG DELIVERY REVIEWS
- Rapid Exchange Between Free and Bound States in RNA–Dendrimer Polyplexes: Implications on the Mechanism of Delivery and Release
- (2015) Anisha Shakya et al. BIOMACROMOLECULES
- MicroRNA nomenclature and the need for a revised naming prescription
- (2015) Hikmet Budak et al. Briefings in Functional Genomics
- The dendritic effect illustrated with phosphorus dendrimers
- (2015) Anne-Marie Caminade et al. CHEMICAL SOCIETY REVIEWS
- Nanoparticle corona for proteins: mechanisms of interaction between dendrimers and proteins
- (2015) Dzmitry Shcharbin et al. COLLOIDS AND SURFACES B-BIOINTERFACES
- Surface decorations of poly(amidoamine) dendrimer by various pendant moieties for improved delivery of nucleic acid materials
- (2015) Ali Dehshahri et al. COLLOIDS AND SURFACES B-BIOINTERFACES
- Anticancer siRNA cocktails as a novel tool to treat cancer cells. Part (A). Mechanisms of interaction
- (2015) Maksim Ionov et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Anticancer siRNA cocktails as a novel tool to treat cancer cells. Part (B). Efficiency of pharmacological action
- (2015) Volha Dzmitruk et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- In vivo delivery of siRNA to the brain by carbosilane dendrimer
- (2015) Mª Jesús Serramía et al. JOURNAL OF CONTROLLED RELEASE
- Potential Use of Thioalkylated Mannose-Modified Dendrimer (G3)/α-Cyclodextrin Conjugate as an NF-κB siRNA Carrier for the Treatment of Fulminant Hepatitis
- (2015) Keiichi Motoyama et al. MOLECULAR PHARMACEUTICS
- Promoting siRNA delivery via enhanced cellular uptake using an arginine-decorated amphiphilic dendrimer
- (2015) Xiaoxuan Liu et al. Nanoscale
- miRNA Nomenclature: A View Incorporating Genetic Origins, Biosynthetic Pathways, and Sequence Variants
- (2015) T. Desvignes et al. TRENDS IN GENETICS
- RNA-Based TWIST1 Inhibition via Dendrimer Complex to Reduce Breast Cancer Cell Metastasis
- (2015) James Finlay et al. Biomed Research International
- Efficient delivery of small interfering RNA into cancer cells using dodecylated dendrimers
- (2015) Hong Chang et al. Journal of Materials Chemistry B
- siRNA Versus miRNA as Therapeutics for Gene Silencing
- (2015) Jenny K W Lam et al. Molecular Therapy-Nucleic Acids
- Adaptive Amphiphilic Dendrimer-Based Nanoassemblies as Robust and Versatile siRNA Delivery Systems
- (2014) Xiaoxuan Liu et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Ionizable Amphiphilic Dendrimer-Based Nanomaterials with Alkyl-Chain-Substituted Amines for Tunable siRNA Delivery to the Liver Endothelium In Vivo
- (2014) Omar F. Khan et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Arginine-Terminated Generation 4 PAMAM Dendrimer as an Effective Nanovector for Functional siRNA Delivery in Vitro and in Vivo
- (2014) Cheng Liu et al. BIOCONJUGATE CHEMISTRY
- MicroRNAs in personalized cancer therapy
- (2014) S. Sethi et al. CLINICAL GENETICS
- The role of caveolin-1 and syndecan-4 in the internalization of PEGylated PAMAM dendrimer polyplexes into myoblast and hepatic cells
- (2014) Wenwen Shen et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- Therapeutic face of RNAi:in vivochallenges
- (2014) Hojat Borna et al. EXPERT OPINION ON BIOLOGICAL THERAPY
- Cationic star-shaped polymer as an siRNA carrier for reducing MMP-9 expression in skin fibroblast cells and promoting wound healing in diabetic rats
- (2014) Yan Li et al. International Journal of Nanomedicine
- How to study dendrimers and dendriplexes III. Biodistribution, pharmacokinetics and toxicity in vivo
- (2014) Dzmitry Shcharbin et al. JOURNAL OF CONTROLLED RELEASE
- Carbosilane dendrimers as gene delivery agents for the treatment of HIV infection
- (2014) Ana Judith Perisé-Barrios et al. JOURNAL OF CONTROLLED RELEASE
- Potential use of glucuronylglucosyl-β-cyclodextrin/dendrimer conjugate (G2) as a siRNA carrier for the treatment of familial amyloidotic polyneuropathy
- (2014) Takayuki Anno et al. JOURNAL OF DRUG TARGETING
- Combination of Dendrimer-Nanovector-Mediated Small Interfering RNA Delivery to Target Akt with the Clinical Anticancer Drug Paclitaxel for Effective and Potent Anticancer Activity in Treating Ovarian Cancer
- (2014) Shashwati Kala et al. JOURNAL OF MEDICINAL CHEMISTRY
- Targeted delivery of Dicer-substrate siRNAs using a dual targeting peptide decorated dendrimer delivery system
- (2014) Xiaoxuan Liu et al. Nanomedicine-Nanotechnology Biology and Medicine
- Regulation of microRNA biogenesis
- (2014) Minju Ha et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Downregulation of miR-21 Enhances Chemotherapeutic Effect of Taxol in Breast Carcinoma Cells
- (2014) Mei Mei et al. TECHNOLOGY IN CANCER RESEARCH & TREATMENT
- Dendrimers: synthesis, applications, and properties
- (2014) Elham Abbasi et al. Nanoscale Research Letters
- Friend or foe: the role of microRNA in chemotherapy resistance
- (2013) Haoran Li et al. ACTA PHARMACOLOGICA SINICA
- Cationic Dendron-Bearing Lipids: Investigating Structure–Activity Relationships for Small Interfering RNA Delivery
- (2013) Yu Zhang et al. BIOMACROMOLECULES
- Functionalized dendrimer-based delivery of angiotensin type 1 receptor siRNA for preserving cardiac function following infarction
- (2013) Jie Liu et al. BIOMATERIALS
- Novel ‘SiC’ carbosilane dendrimers as carriers for anti-HIV nucleic acids: Studies on complexation and interaction with blood cells
- (2013) Elzbieta Pedziwiatr-Werbicka et al. COLLOIDS AND SURFACES B-BIOINTERFACES
- Poly(amidoamine) dendrimer complexes as a platform for gene delivery
- (2013) Dzmitry Shcharbin et al. Expert Opinion on Drug Delivery
- DNA delivery with hyperbranched polylysine: A comparative study with linear and dendritic polylysine
- (2013) Zuzana Kadlecova et al. JOURNAL OF CONTROLLED RELEASE
- Delivery materials for siRNA therapeutics
- (2013) Rosemary Kanasty et al. NATURE MATERIALS
- Positively charged phosphorus dendrimers. An overview of their properties
- (2013) Anne-Marie Caminade et al. NEW JOURNAL OF CHEMISTRY
- Poly(amido amine) is an ideal carrier of miR-7 for enhancing gene silencing effects on the EGFR pathway in U251 glioma cells
- (2013) XIAOZHI LIU et al. ONCOLOGY REPORTS
- Dendrimer as nanocarrier for drug delivery
- (2013) Prashant Kesharwani et al. PROGRESS IN POLYMER SCIENCE
- Nucleic Acid Delivery: The Missing Pieces of the Puzzle?
- (2012) Juliane Nguyen et al. ACCOUNTS OF CHEMICAL RESEARCH
- RNAi-based nanomedicines for targeted personalized therapy
- (2012) Ala Daka et al. ADVANCED DRUG DELIVERY REVIEWS
- An Amphiphilic Dendrimer for Effective Delivery of Small Interfering RNA and Gene Silencing In Vitro and In Vivo
- (2012) Tianzhu Yu et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Dendrimeric Bowties Featuring Hemispheric-Selective Decoration of Ligands for microRNA-Based Therapy
- (2012) Warren D. Gray et al. BIOMACROMOLECULES
- Validation of a Generation 4 Phosphorus-Containing Polycationic Dendrimer for Gene Delivery Against HIV-1
- (2012) V. Briz et al. CURRENT MEDICINAL CHEMISTRY
- Synergistic inhibition of human glioma cell line by temozolomide and PAMAM-mediated miR-21i
- (2012) Xiao-Min Qian et al. JOURNAL OF APPLIED POLYMER SCIENCE
- Influence of fourth generation poly(propyleneimine) dendrimers on blood cells
- (2012) Barbara Ziemba et al. JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A
- Carbosilane Dendrimers are a Non-Viral Delivery System for Antisense Oligonucleotides: Characterization of Dendriplexes
- (2012) Elzbieta Pedziwiatr-Werbicka et al. Journal of Biomedical Nanotechnology
- Overcoming drug resistance of MCF-7/ADR cells by altering intracellular distribution of doxorubicin via MVP knockdown with a novel siRNA polyamidoamine-hyaluronic acid complex
- (2012) Min Han et al. JOURNAL OF CONTROLLED RELEASE
- Stability of Dendriplexes Formed by Anti-HIV Genetic Material and Poly(propylene imine) Dendrimers in the Presence of Glucosaminoglycans
- (2012) Michal Szewczyk et al. JOURNAL OF PHYSICAL CHEMISTRY B
- Sequence-Dependent Synergistic Inhibition of Human Glioma Cell Lines by Combined Temozolomide and miR-21 Inhibitor Gene Therapy
- (2012) Xiaomin Qian et al. MOLECULAR PHARMACEUTICS
- Endgame: Glybera Finally Recommended for Approval as the First Gene Therapy Drug in the European Union
- (2012) Seppo Ylä-Herttuala MOLECULAR THERAPY
- RNA therapeutics: beyond RNA interference and antisense oligonucleotides
- (2012) Ryszard Kole et al. NATURE REVIEWS DRUG DISCOVERY
- The protein corona of dendrimers: PAMAM binds and activates complement proteins in human plasma in a generation dependent manner
- (2012) Anna Åkesson et al. RSC Advances
- Multifunctional Triblock Nanocarrier (PAMAM-PEG-PLL) for the Efficient Intracellular siRNA Delivery and Gene Silencing
- (2011) Mahesh L. Patil et al. ACS Nano
- Efficient, Non-Toxic Hybrid PPV-PAMAM Dendrimer as a Gene Carrier for Neuronal Cells
- (2011) Ana C. Rodrigo et al. BIOMACROMOLECULES
- Endosomal escape and the knockdown efficiency of liposomal-siRNA by the fusogenic peptide shGALA
- (2011) Yu Sakurai et al. BIOMATERIALS
- Locked vs. unlocked nucleic acids (LNA vs. UNA): contrasting structures work towards common therapeutic goals
- (2011) Meghan A. Campbell et al. CHEMICAL SOCIETY REVIEWS
- Dendrimer-mediated siRNA delivery knocks down Beclin 1 and potentiates NMDA-mediated toxicity in rat cortical neurons
- (2011) María D. Pérez-Carrión et al. JOURNAL OF NEUROCHEMISTRY
- Systemic Administration of Combinatorial dsiRNAs via Nanoparticles Efficiently Suppresses HIV-1 Infection in Humanized Mice
- (2011) Jiehua Zhou et al. MOLECULAR THERAPY
- Inhibition of p42 MAPK using a nonviral vector-delivered siRNA potentiates the anti-tumor effect of metformin in prostate cancer cells
- (2011) Silvia Monteagudo et al. Nanomedicine
- Current prospects for RNA interference-based therapies
- (2011) Beverly L. Davidson et al. NATURE REVIEWS GENETICS
- Tumor-Selective Delivery of Macromolecular Drugs via the EPR Effect: Background and Future Prospects
- (2010) Hiroshi Maeda BIOCONJUGATE CHEMISTRY
- Carbosilane Dendrimers to Transfect Human Astrocytes with Small Interfering RNA Targeting Human Immunodeficiency Virus
- (2010) Jose Luis Jiménez et al. BIODRUGS
- MicroRNA-21 inhibitor sensitizes human glioblastoma cells U251 (PTEN-mutant) and LN229 (PTEN-wild type) to taxol
- (2010) Yu Ren et al. BMC CANCER
- MicroRNA and drug resistance
- (2010) J Ma et al. CANCER GENE THERAPY
- Biomedical applications of dendrimers: a tutorial
- (2010) Meredith A. Mintzer et al. CHEMICAL SOCIETY REVIEWS
- Gene Therapy in HIV-Infected Cells to Decrease Viral Impact by Using an Alternative Delivery Method
- (2010) Teresa Gonzalo et al. ChemMedChem
- Carbosilane dendrimers NN8 and NN16 form a stable complex with siGAG1
- (2010) Dzmitry Shcharbin et al. COLLOIDS AND SURFACES B-BIOINTERFACES
- Dendrimer toxicity: Let's meet the challenge
- (2010) Keerti Jain et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Co-delivery of as-miR-21 and 5-FU by Poly(amidoamine) Dendrimer Attenuates Human Glioma Cell Growth in Vitro
- (2010) Yu Ren et al. JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION
- Endocytosis of nanomedicines
- (2010) Gaurav Sahay et al. JOURNAL OF CONTROLLED RELEASE
- Biological properties of phosphorus dendrimers
- (2010) Anne-Marie Caminade et al. NEW JOURNAL OF CHEMISTRY
- Internally Cationic Polyamidoamine PAMAM-OH Dendrimers for siRNA Delivery: Effect of the Degree of Quaternization and Cancer Targeting
- (2009) Mahesh L. Patil et al. BIOMACROMOLECULES
- MicroRNAs: Target Recognition and Regulatory Functions
- (2009) David P. Bartel CELL
- Suppression of breast cancer cellsin vitroby polyamidoamine-dendrimer-mediated 5-fluorouracil chemotherapy combined with antisense micro-RNA 21 gene therapy
- (2009) Mei Mei et al. JOURNAL OF APPLIED POLYMER SCIENCE
- How to study dendriplexes I: Characterization
- (2009) Dzmitry Shcharbin et al. JOURNAL OF CONTROLLED RELEASE
- Surface-engineered targeted PPI dendrimer for efficient intracellular and intratumoral siRNA delivery
- (2009) Oleh Taratula et al. JOURNAL OF CONTROLLED RELEASE
- How to study dendriplexes II: Transfection and cytotoxicity
- (2009) Dzmitry Shcharbin et al. JOURNAL OF CONTROLLED RELEASE
- In vivo siRNA delivery with dendritic poly(l-lysine) for the treatment of hypercholesterolemia
- (2009) Kazuto Watanabe et al. Molecular BioSystems
- Knocking down barriers: advances in siRNA delivery
- (2009) Kathryn A. Whitehead et al. NATURE REVIEWS DRUG DISCOVERY
- Highly Efficient Transfection of Rat Cortical Neurons Using Carbosilane Dendrimers Unveils a Neuroprotective Role for HIF-1α in Early Chemical Hypoxia-Mediated Neurotoxicity
- (2009) Inmaculada Posadas et al. PHARMACEUTICAL RESEARCH
- Surface-Modified and Internally Cationic Polyamidoamine Dendrimers for Efficient siRNA Delivery
- (2008) Mahesh L. Patil et al. BIOCONJUGATE CHEMISTRY
- Oligoethylenimine-grafted polypropylenimine dendrimers as degradable and biocompatible synthetic vectors for gene delivery
- (2008) Verena Russ et al. JOURNAL OF CONTROLLED RELEASE
- Characterization of carbosilane dendrimers as effective carriers of siRNA to HIV-infected lymphocytes
- (2008) Nick Weber et al. JOURNAL OF CONTROLLED RELEASE
- Polycationic phosphorus dendrimers: synthesis, characterization, study of cytotoxicity, complexation of DNA, and transfection experiments
- (2008) Clément Padié et al. NEW JOURNAL OF CHEMISTRY
- Efficient delivery of siRNA using dendritic poly(l-lysine) for loss-of-function analysis
- (2007) Yusuke Inoue et al. JOURNAL OF CONTROLLED RELEASE
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