标题
Drug Resistance in Non-Small Cell Lung Cancer: A Potential for NOTCH Targeting?
作者
关键词
-
出版物
Frontiers in Oncology
Volume 8, Issue -, Pages -
出版商
Frontiers Media SA
发表日期
2018-07-24
DOI
10.3389/fonc.2018.00267
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Beyond Concurrent Chemoradiation: The Emerging Role of PD-1/PD-L1 Inhibitors in Stage III Lung Cancer
- (2018) Neal S. McCall et al. CLINICAL CANCER RESEARCH
- Genomic heterogeneity of ALK fusion breakpoints in non-small-cell lung cancer
- (2018) Jason N Rosenbaum et al. MODERN PATHOLOGY
- Inhibiting IGF-1R attenuates cell proliferation and VEGF production in IGF-1R over-expressing EGFR mutant non-small cell lung cancer cells
- (2017) Chang Dong Yeo et al. EXPERIMENTAL LUNG RESEARCH
- Selumetinib Plus Docetaxel Compared With Docetaxel Alone and Progression-Free Survival in Patients With KRAS-Mutant Advanced Non–Small Cell Lung Cancer
- (2017) Pasi A. Jänne et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- The next generation of immunotherapy: keeping lung cancer in check
- (2017) Ashwin Somasundaram et al. Journal of Hematology & Oncology
- Nivolumab plus ipilimumab as first-line treatment for advanced non-small-cell lung cancer (CheckMate 012): results of an open-label, phase 1, multicohort study
- (2017) Matthew D Hellmann et al. LANCET ONCOLOGY
- Intra-tumor heterogeneity from a cancer stem cell perspective
- (2017) Pramudita R. Prasetyanti et al. Molecular Cancer
- Gamma Secretase Inhibition by BMS-906024 Enhances Efficacy of Paclitaxel in Lung Adenocarcinoma
- (2017) Katherine M. Morgan et al. MOLECULAR CANCER THERAPEUTICS
- Durvalumab after Chemoradiotherapy in Stage III Non–Small-Cell Lung Cancer
- (2017) Scott J. Antonia et al. NEW ENGLAND JOURNAL OF MEDICINE
- Antagonism of EGFR and Notch limits resistance to EGFR inhibitors and radiation by decreasing tumor-initiating cell frequency
- (2017) Shi Hu et al. Science Translational Medicine
- Phase IB Trial of the Anti-Cancer Stem Cell DLL4-Binding Agent Demcizumab with Pemetrexed and Carboplatin as First-Line Treatment of Metastatic Non-Squamous NSCLC
- (2017) Mark J. McKeage et al. Targeted Oncology
- EGFR mutation in squamous cell carcinoma of the lung: does it carry the same connotation as in adenocarcinomas?
- (2017) Amit Joshi et al. OncoTargets and Therapy
- Epidermal growth factor receptor T790M mutation-positive metastatic non-small-cell lung cancer: focus on osimertinib (AZD9291)
- (2017) Nibal Saad et al. OncoTargets and Therapy
- Prognostic roles of mRNA expression of notch receptors in non-small cell lung cancer
- (2017) Jianwen Xiong et al. Oncotarget
- Expression of Notch Gene and Its Impact on Survival of Patients with Resectable Non-small Cell Lung Cancer
- (2017) Chung-Yu Chen et al. Journal of Cancer
- KRAS G12C mutation as a poor prognostic marker of pemetrexed treatment in non-small cell lung cancer
- (2017) Sehhoon Park et al. KOREAN JOURNAL OF INTERNAL MEDICINE
- The Notch intracellular domain integrates signals from Wnt, Hedgehog, TGFβ/BMP and hypoxia pathways
- (2016) Tilman Borggrefe et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Prolonged pemetrexed pretreatment augments persistence of cisplatin-induced DNA damage and eliminates resistant lung cancer stem-like cells associated with EMT
- (2016) Colin Charles Tièche et al. BMC CANCER
- Restricted Location of PSEN2/γ-Secretase Determines Substrate Specificity and Generates an Intracellular Aβ Pool
- (2016) Ragna Sannerud et al. CELL
- Metabolic Heterogeneity in Human Lung Tumors
- (2016) Christopher T. Hensley et al. CELL
- Negative control of CSL gene transcription by stress/DNA damage response and p53
- (2016) Elena Menietti et al. CELL CYCLE
- A first-in-human phase I study of the oral Notch inhibitor, LY900009, in patients with advanced cancer
- (2016) Shubham Pant et al. EUROPEAN JOURNAL OF CANCER
- KRAS driven expression signature has prognostic power superior to mutation status in non-small cell lung cancer
- (2016) Ádám Nagy et al. INTERNATIONAL JOURNAL OF CANCER
- Inhibition of Notch and HIF enhances the antitumor effect of radiation in Notch expressing lung cancer
- (2016) Yasuyuki Ikezawa et al. International Journal of Clinical Oncology
- Combined antitumor effect of γ-secretase inhibitor and ABT-737 in Notch-expressing non-small cell lung cancer
- (2016) Jun Sakakibara-Konishi et al. International Journal of Clinical Oncology
- Blockade of Notch3 inhibits the stem-like property and is associated with ALDH1A1 and CD44 via autophagy in non-small lung cancer
- (2016) YUANYUAN MA et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- Development of a RNA-Seq Based Prognostic Signature in Lung Adenocarcinoma
- (2016) Sudhanshu Shukla et al. JNCI-Journal of the National Cancer Institute
- Acquired C797S Mutation upon Treatment with a T790M-Specific Third-Generation EGFR Inhibitor (HM61713) in Non–Small Cell Lung Cancer
- (2016) Haa-Na Song et al. Journal of Thoracic Oncology
- Gemcitabine-Induced Autophagy Protects Human Lung Cancer Cells from Apoptotic Death
- (2016) Hui-Mei Wu et al. LUNG
- Simultaneous blockade of VEGF and Dll4 by HD105, a bispecific antibody, inhibits tumor progression and angiogenesis
- (2016) Dongheon Lee et al. mAbs
- Combined inhibition of DDR1 and Notch signaling is a therapeutic strategy for KRAS-driven lung adenocarcinoma
- (2016) Chiara Ambrogio et al. NATURE MEDICINE
- Epithelial Notch signaling regulates lung alveolar morphogenesis and airway epithelial integrity
- (2016) Po-Nien Tsao et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- NOTCH blockade combined with radiation therapy and temozolomide prolongs survival of orthotopic glioblastoma
- (2016) Sanaz Yahyanejad et al. Oncotarget
- Anti-cancer effects of curcumin on lung cancer through the inhibition of EZH2 and NOTCH1
- (2016) Guo-Qing Wu et al. Oncotarget
- Development of a RNA-Seq Based Prognostic Signature in Lung Adenocarcinoma
- (2016) Sudhanshu Shukla et al. JNCI-Journal of the National Cancer Institute
- Does Notch play a tumor suppressor role across diverse squamous cell carcinomas?
- (2016) Min Zhang et al. Cancer Medicine
- Notch-1 Confers Chemoresistance in Lung Adenocarcinoma to Taxanes through AP-1/microRNA-451 Mediated Regulation of MDR-1
- (2016) Jiayuan Huang et al. Molecular Therapy-Nucleic Acids
- Frequency and distribution of Notch mutations in tumor cell lines
- (2015) Anders Peter Mutvei et al. BMC CANCER
- Targeting Notch Signaling with a Notch2/Notch3 Antagonist (Tarextumab) Inhibits Tumor Growth and Decreases Tumor-Initiating Cell Frequency
- (2015) W.-C. Yen et al. CLINICAL CANCER RESEARCH
- A Phase I First-in-Human Study of Enoticumab (REGN421), a Fully Human Delta-like Ligand 4 (Dll4) Monoclonal Antibody in Patients with Advanced Solid Tumors
- (2015) E. G. Chiorean et al. CLINICAL CANCER RESEARCH
- γ Secretase Inhibitor BMS-708163 Reverses Resistance to EGFR Inhibitor via the PI3K/Akt Pathway in Lung Cancer
- (2015) Mian Xie et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Cancer metabolism and the Warburg effect: the role of HIF-1 and PI3K
- (2015) Rupert Courtnay et al. MOLECULAR BIOLOGY REPORTS
- 23814, an Inhibitory Antibody of Ligand-Mediated Notch1 Activation, Modulates Angiogenesis and Inhibits Tumor Growth without Gastrointestinal Toxicity
- (2015) T. Proia et al. MOLECULAR CANCER THERAPEUTICS
- Therapeutic antibodies reveal Notch control of transdifferentiation in the adult lung
- (2015) Daniel Lafkas et al. NATURE
- Refining the treatment of NSCLC according to histological and molecular subtypes
- (2015) Anish Thomas et al. Nature Reviews Clinical Oncology
- The cancer stem cell gamble
- (2015) J. Kaiser SCIENCE
- Clonal status of actionable driver events and the timing of mutational processes in cancer evolution
- (2015) Nicholas McGranahan et al. Science Translational Medicine
- Blocking the epithelial-to-mesenchymal transition pathway abrogates resistance to anti-folate chemotherapy in lung cancer
- (2015) S-Q Liang et al. Cell Death & Disease
- Notch signaling molecules as prognostic biomarkers for non-small cell lung cancer
- (2015) MENG-MENG JIN et al. Oncology Letters
- Targeting Notch to overcome radiation resistance
- (2015) Sanaz Yahyanejad et al. Oncotarget
- Cancer-Associated Fibroblasts: Their Characteristics and Their Roles in Tumor Growth
- (2015) Kazuyoshi Shiga et al. Cancers
- Meta-analysis reveals the correlation of Notch signaling with non-small cell lung cancer progression and prognosis
- (2015) Xun Yuan et al. Scientific Reports
- 2nd ESMO Consensus Conference on Lung Cancer: non-small-cell lung cancer first-line/second and further lines of treatment in advanced disease
- (2014) B. Besse et al. ANNALS OF ONCOLOGY
- Cancer: Evolution Within a Lifetime
- (2014) Marco Gerlinger et al. Annual Review of Genetics
- Blocking the NOTCH pathway can inhibit the growth of CD133-positive A549 cells and sensitize to chemotherapy
- (2014) Juntao Liu et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- A parallel-arm phase I trial of the humanised anti-IGF-1R antibody dalotuzumab in combination with the AKT inhibitor MK-2206, the mTOR inhibitor ridaforolimus, or the NOTCH inhibitor MK-0752, in patients with advanced solid tumours
- (2014) I Brana et al. BRITISH JOURNAL OF CANCER
- EGFR Blockade Enriches for Lung Cancer Stem-like Cells through Notch3-Dependent Signaling
- (2014) R. R. Arasada et al. CANCER RESEARCH
- Podoplanin-Positive Cancer-Associated Fibroblasts in the Tumor Microenvironment Induce Primary Resistance to EGFR-TKIs in Lung Adenocarcinoma with EGFR Mutation
- (2014) Tatsuya Yoshida et al. CLINICAL CANCER RESEARCH
- A Phase I, Dose-Finding Study in Patients with Advanced Solid Malignancies of the Oral -Secretase Inhibitor PF-03084014
- (2014) W. A. Messersmith et al. CLINICAL CANCER RESEARCH
- A Phase I Dose Escalation and Expansion Study of the Anticancer Stem Cell Agent Demcizumab (Anti-DLL4) in Patients with Previously Treated Solid Tumors
- (2014) D. C. Smith et al. CLINICAL CANCER RESEARCH
- MicroRNA-451 induces epithelial–mesenchymal transition in docetaxel-resistant lung adenocarcinoma cells by targeting proto-oncogene c-Myc
- (2014) Dongqin Chen et al. EUROPEAN JOURNAL OF CANCER
- Hypoxia induces resistance to ALK inhibitors in the H3122 non-small cell lung cancer cell line with an ALK rearrangement via epithelial-mesenchymal transition
- (2014) AKIHIRO KOGITA et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- Acute Toxicity of Subcutaneously Administered Vitamin E Isomers Delta- and Gamma-Tocotrienol in Mice
- (2014) Sibyl N. Swift et al. INTERNATIONAL JOURNAL OF TOXICOLOGY
- An epigenetic mechanism of resistance to targeted therapy in T cell acute lymphoblastic leukemia
- (2014) Birgit Knoechel et al. NATURE GENETICS
- Therapeutic modulation of Notch signalling — are we there yet?
- (2014) Emma R. Andersson et al. NATURE REVIEWS DRUG DISCOVERY
- Intratumor heterogeneity in localized lung adenocarcinomas delineated by multiregion sequencing
- (2014) J. Zhang et al. SCIENCE
- Tracking Genomic Cancer Evolution for Precision Medicine: The Lung TRACERx Study
- (2014) Mariam Jamal-Hanjani et al. PLOS BIOLOGY
- Prognostic value of metabolic metrics extracted from baseline positron emission tomography images in non-small cell lung cancer
- (2013) Sara Carvalho et al. ACTA ONCOLOGICA
- A phase I study of the combination of ro4929097 and cediranib in patients with advanced solid tumours (PJC-004/NCI 8503)
- (2013) S Sahebjam et al. BRITISH JOURNAL OF CANCER
- Deadly crosstalk: Notch signaling at the intersection of EMT and cancer stem cells
- (2013) Ingrid Espinoza et al. CANCER LETTERS
- Notch signaling pathway targeted therapy suppresses tumor progression and metastatic spread in pancreatic cancer
- (2013) Shinichi Yabuuchi et al. CANCER LETTERS
- In Vivo Mapping of Notch Pathway Activity in Normal and Stress Hematopoiesis
- (2013) Philmo Oh et al. Cell Stem Cell
- Notch Pathway Activity Identifies Cells with Cancer Stem Cell-like Properties and Correlates with Worse Survival in Lung Adenocarcinoma
- (2013) K. A. Hassan et al. CLINICAL CANCER RESEARCH
- Preclinical and Clinical Studies of Gamma Secretase Inhibitors with Docetaxel on Human Breast Tumors
- (2013) A. F. Schott et al. CLINICAL CANCER RESEARCH
- Notch-1 contributes to epidermal growth factor receptor tyrosine kinase inhibitor acquired resistance in non-small cell lung cancer in vitro and in vivo
- (2013) Mian Xie et al. EUROPEAN JOURNAL OF CANCER
- A phase Ib combination study of RO4929097, a gamma-secretase inhibitor, and temsirolimus in patients with advanced solid tumors
- (2013) Ivan Diaz-Padilla et al. INVESTIGATIONAL NEW DRUGS
- Constitutive Activation of Signal Transducer and Activator of Transcription 3 (STAT3) and Nuclear Factor κB Signaling in Glioblastoma Cancer Stem Cells Regulates the Notch Pathway
- (2013) Jo Meagan Garner et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Signatures of mutational processes in human cancer
- (2013) Ludmil B. Alexandrov et al. NATURE
- The quest to overcome resistance to EGFR-targeted therapies in cancer
- (2013) Curtis R Chong et al. NATURE MEDICINE
- Extract of Bryophyllum laetivirens reverses etoposide resistance in human lung A549 cancer cells by downregulation of NF-κB
- (2013) CHUTIMA KAEWPIBOON et al. ONCOLOGY REPORTS
- Targeting Notch signaling pathway in cancer: Clinical development advances and challenges
- (2013) Naoko Takebe et al. PHARMACOLOGY & THERAPEUTICS
- Generation and Characterisation of Cisplatin-Resistant Non-Small Cell Lung Cancer Cell Lines Displaying a Stem-Like Signature
- (2013) Martin P. Barr et al. PLoS One
- Pterostilbene Exerts Antitumor Activity via the Notch1 Signaling Pathway in Human Lung Adenocarcinoma Cells
- (2013) Yang Yang et al. PLoS One
- EGFR Mutations in Indian Lung Cancer Patients: Clinical Correlation and Outcome to EGFR Targeted Therapy
- (2013) Vanita Noronha et al. PLoS One
- High NOTCH activity induces radiation resistance in non small cell lung cancer
- (2013) Jan Theys et al. RADIOTHERAPY AND ONCOLOGY
- Cancer Genome Landscapes
- (2013) B. Vogelstein et al. SCIENCE
- Intermittent Oral Coadministration of a Gamma Secretase Inhibitor with Dexamethasone Mitigates Intestinal Goblet Cell Hyperplasia in Rats
- (2013) Shirley A. Aguirre et al. TOXICOLOGIC PATHOLOGY
- NF-κB non-cell-autonomously regulates cancer stem cell populations in the basal-like breast cancer subtype
- (2013) Mizuki Yamamoto et al. Nature Communications
- Anti-VEGF Therapies in the Clinic
- (2013) K. L. Meadows et al. Cold Spring Harbor Perspectives in Medicine
- Soy Food Intake and Risk of Lung Cancer: Evidence From the Shanghai Women's Health Study and a Meta-Analysis
- (2012) Gong Yang et al. AMERICAN JOURNAL OF EPIDEMIOLOGY
- γ-Secretase inhibitor enhances antitumour effect of radiation in Notch-expressing lung cancer
- (2012) H Mizugaki et al. BRITISH JOURNAL OF CANCER
- Therapeutic Effect of γ-Secretase Inhibition in KrasG12V-Driven Non-Small Cell Lung Carcinoma by Derepression of DUSP1 and Inhibition of ERK
- (2012) Antonio Maraver et al. CANCER CELL
- Berry anthocyanidins synergistically suppress growth and invasive potential of human non-small-cell lung cancer cells
- (2012) Hina Kausar et al. CANCER LETTERS
- Cisplatin Selects for Multidrug-Resistant CD133+ Cells in Lung Adenocarcinoma by Activating Notch Signaling
- (2012) Y.-P. Liu et al. CANCER RESEARCH
- Genomic Landscape of Non-Small Cell Lung Cancer in Smokers and Never-Smokers
- (2012) Ramaswamy Govindan et al. CELL
- Mapping the Hallmarks of Lung Adenocarcinoma with Massively Parallel Sequencing
- (2012) Marcin Imielinski et al. CELL
- Molecular Pathways: Context-Dependent Approaches to Notch Targeting as Cancer Therapy
- (2012) A. M. Egloff et al. CLINICAL CANCER RESEARCH
- Different assemblies of Notch receptors coordinate the distribution of the major bronchial Clara, ciliated and neuroendocrine cells
- (2012) M. Morimoto et al. DEVELOPMENT
- Mutant p53 cooperates with ETS2 to promote etoposide resistance
- (2012) P. M. Do et al. GENES & DEVELOPMENT
- Delta-tocotrienol suppresses Notch-1 pathway by upregulating miR-34a in nonsmall cell lung cancer cells
- (2012) Xiangming Ji et al. INTERNATIONAL JOURNAL OF CANCER
- Phase I Pharmacologic and Pharmacodynamic Study of the Gamma Secretase (Notch) Inhibitor MK-0752 in Adult Patients With Advanced Solid Tumors
- (2012) Ian Krop et al. JOURNAL OF CLINICAL ONCOLOGY
- Chemotherapy for pulmonary large cell neuroendocrine carcinoma: Similar to that for small cell lung cancer or non-small cell lung cancer?
- (2012) Jong-Mu Sun et al. LUNG CANCER
- The molecular evolution of acquired resistance to targeted EGFR blockade in colorectal cancers
- (2012) Luis A. Diaz Jr et al. NATURE
- Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion Sequencing
- (2012) Marco Gerlinger et al. NEW ENGLAND JOURNAL OF MEDICINE
- Targeting Notch, a key pathway for ovarian cancer stem cells, sensitizes tumors to platinum therapy
- (2012) S. M. McAuliffe et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- NOTCH1 Is Required for Regeneration of Clara Cells During Repair of Airway Injury
- (2012) Yiming Xing et al. STEM CELLS
- CH5424802, a Selective ALK Inhibitor Capable of Blocking the Resistant Gatekeeper Mutant
- (2011) Hiroshi Sakamoto et al. CANCER CELL
- Efficacy of gefitinib for non-adenocarcinoma non-small-cell lung cancer patients harboring epidermal growth factor receptor mutations: A pooled analysis of published reports
- (2011) Takehito Shukuya et al. CANCER SCIENCE
- Hallmarks of Cancer: The Next Generation
- (2011) Douglas Hanahan et al. CELL
- Notch-Dependent Differentiation of Adult Airway Basal Stem Cells
- (2011) Jason R. Rock et al. Cell Stem Cell
- Proteolytic Cleavage of Notch: “HIT and RUN”
- (2011) G. van Tetering et al. CURRENT MOLECULAR MEDICINE
- Dll1- and Dll4-Mediated Notch Signaling Are Required for Homeostasis of Intestinal Stem Cells
- (2011) Luca Pellegrinet et al. GASTROENTEROLOGY
- Microtubule disruption targets HIF-1α mRNA to cytoplasmic P-bodies for translational repression
- (2011) Marisa Carbonaro et al. JOURNAL OF CELL BIOLOGY
- Activation of Notch-1 enhances epithelial-mesenchymal transition in gefitinib-acquired resistant lung cancer cells
- (2011) Mian Xie et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Crosstalk between the canonical NF-κB and Notch signaling pathways inhibits Pparγ expression and promotes pancreatic cancer progression in mice
- (2011) Eleni Maniati et al. JOURNAL OF CLINICAL INVESTIGATION
- Hypo- and hyperactivated Notch signaling induce a glycolytic switch through distinct mechanisms
- (2011) S. K.- J. Landor et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Loss-of-function mutations in Notch receptors in cutaneous and lung squamous cell carcinoma
- (2011) N. J. Wang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Genotypic and Histological Evolution of Lung Cancers Acquiring Resistance to EGFR Inhibitors
- (2011) L. V. Sequist et al. Science Translational Medicine
- The Notch/Hes1 Pathway Sustains NF-κB Activation through CYLD Repression in T Cell Leukemia
- (2010) Lluis Espinosa et al. CANCER CELL
- Cancer-Associated Fibroblasts Are Activated in Incipient Neoplasia to Orchestrate Tumor-Promoting Inflammation in an NF-κB-Dependent Manner
- (2010) Neta Erez et al. CANCER CELL
- NOTCH Signaling Is Required for Formation and Self-Renewal of Tumor-Initiating Cells and for Repression of Secretory Cell Differentiation in Colon Cancer
- (2010) S. S. Sikandar et al. CANCER RESEARCH
- Aldehyde Dehydrogenase Activity Selects for Lung Adenocarcinoma Stem Cells Dependent on Notch Signaling
- (2010) J. P. Sullivan et al. CANCER RESEARCH
- Anti-DLL4 Inhibits Growth and Reduces Tumor-Initiating Cell Frequency in Colorectal Tumors with Oncogenic KRAS Mutations
- (2010) M. Fischer et al. CANCER RESEARCH
- Breast Cancer Stem Cells: Something Out of Notching?
- (2010) H. Harrison et al. CANCER RESEARCH
- The Role of Notch Signaling Pathway in Epithelial-Mesenchymal Transition (EMT) During Development and Tumor Aggressiveness
- (2010) Zhiwei Wang et al. CURRENT DRUG TARGETS
- Canonical Notch signaling in the developing lung is required for determination of arterial smooth muscle cells and selection of Clara versus ciliated cell fate
- (2010) M. Morimoto et al. JOURNAL OF CELL SCIENCE
- Meta-Analysis of Concomitant Versus Sequential Radiochemotherapy in Locally Advanced Non–Small-Cell Lung Cancer
- (2010) Anne Aupérin et al. JOURNAL OF CLINICAL ONCOLOGY
- Chronic DLL4 blockade induces vascular neoplasms
- (2010) Minhong Yan et al. NATURE
- Targeting cancer stem cells by inhibiting Wnt, Notch and Hedgehog pathways
- (2010) Naoko Takebe et al. Nature Reviews Clinical Oncology
- Notch-1 stimulates survival of lung adenocarcinoma cells during hypoxia by activating the IGF-1R pathway
- (2010) S Eliasz et al. ONCOGENE
- Molecular Mechanisms of Resistance to Tumour Anti-Angiogenic Strategies
- (2010) Renaud Grépin et al. Journal of Oncology
- Pemetrexed in first-line treatment of non-small cell lung cancer
- (2009) Emilio Esteban et al. CANCER TREATMENT REVIEWS
- The Notch signaling pathway: Transcriptional regulation at Notch target genes
- (2009) T. Borggrefe et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Notch signaling controls the balance of ciliated and secretory cell fates in developing airways
- (2009) P.-N. Tsao et al. DEVELOPMENT
- Notch signaling promotes airway mucous metaplasia and inhibits alveolar development
- (2009) J. S. Guseh et al. DEVELOPMENT
- Jagged1 on Dendritic Cells and Notch on CD4+ T Cells Initiate Lung Allergic Responsiveness by Inducing IL-4 Production
- (2009) M. Okamoto et al. JOURNAL OF IMMUNOLOGY
- Requirement for NF-κB signalling in a mouse model of lung adenocarcinoma
- (2009) Etienne Meylan et al. NATURE
- A human 5′-tyrosyl DNA phosphodiesterase that repairs topoisomerase-mediated DNA damage
- (2009) Felipe Cortes Ledesma et al. NATURE
- Notch3 signaling promotes the development of pulmonary arterial hypertension
- (2009) Xiaodong Li et al. NATURE MEDICINE
- Notch3 cooperates with the EGFR pathway to modulate apoptosis through the induction of bim
- (2009) J Konishi et al. ONCOGENE
- Alterations of the Notch pathway in lung cancer
- (2009) Britta Westhoff et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- KLF4 gene expression is inhibited by the notch signaling pathway that controls goblet cell differentiation in mouse gastrointestinal tract
- (2008) Hai Zheng et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- NOTCH is a key regulator of human T-cell acute leukemia initiating cell activity
- (2008) F. Armstrong et al. BLOOD
- The role of endothelial-to-mesenchymal transition in cancer progression
- (2008) S Potenta et al. BRITISH JOURNAL OF CANCER
- Loss of intestinal crypt progenitor cells owing to inactivation of both Notch1 and Notch2 is accompanied by derepression of CDK inhibitors p27Kip1 and p57Kip2
- (2008) Orbicia Riccio et al. EMBO REPORTS
- γ-Secretase Activation of Notch Signaling Regulates the Balance of Proximal and Distal Fates in Progenitor Cells of the Developing Lung
- (2008) Po-Nien Tsao et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Correlation of EGFR mutations with chromosomal alterations and expression of EGFR, ErbB3 and VEGF in tumor samples of lung adenocarcinoma patients
- (2008) Niels Reinmuth et al. LUNG CANCER
- NUMB controls p53 tumour suppressor activity
- (2008) Ivan N. Colaluca et al. NATURE
- Somatic mutations affect key pathways in lung adenocarcinoma
- (2008) Li Ding et al. NATURE
- γ-secretase inhibitors reverse glucocorticoid resistance in T cell acute lymphoblastic leukemia
- (2008) Pedro J Real et al. NATURE MEDICINE
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