Direct thiolation of aza-heteroaromatic N-oxides with disulfides via copper-catalyzed regioselective C–H bond activation

Synthesis of Alkyl-Substituted Pyrazine N -Oxides by Transition-Metal-Free Oxidative Cross-Coupling Reactions

(2018) Miao Lai et al.   Asian Journal of Organic Chemistry

Synthesis of 2-Acyl-Substituted Pyrazine Derivatives through Silver-Catalyzed Decarboxylative Coupling Reactions

(2018) Yuan Li et al.   ChemistrySelect

Synthesis and initial thermal behavior investigation of 2-alkenyl substituted pyrazine N-oxides

(2018) Ke Zhai et al.   CATALYSIS COMMUNICATIONS

A Direct C2-Selective Phenoxylation and Alkoxylation of Quinoline N -Oxides with Various Phenols and Alcohols in the Presence of H -Phosphonate

(2017) Wen-Zhu Bi et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Iodine/TBHP-Promoted One-Pot Deoxygenation and Direct 2-Sulfonylation of QuinolineN-Oxides with Sodium Sulfinates: Facile and Regioselective Synthesis of 2-Sulfonylquinolines

(2017) Ladawan Sumunnee et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

A base-free, ultrasound accelerated one-pot synthesis of 2-sulfonylquinolines in water

(2017) Long-Yong Xie et al.   GREEN CHEMISTRY

Copper-Catalyzed Direct, Regioselective Arylamination of N-Oxides: Studies To Access Conjugated π-Systems

(2017) Aniruddha Biswas et al.   JOURNAL OF ORGANIC CHEMISTRY

Lewis Acid Catalyzed Dehydrogenative Coupling of Tertiary Propargylic Alcohols with Quinoline N-Oxides

(2017) Ya-Ping Han et al.   JOURNAL OF ORGANIC CHEMISTRY

Visible-Light-Induced C2 Alkylation of Pyridine N-Oxides

(2017) Wen-Man Zhang et al.   JOURNAL OF ORGANIC CHEMISTRY

Aerobic thiyl radical addition/cyclization of N-methacryloyl benzamides for the synthesis of isoquinoline-1,3(2H,4H)-dione derivatives

(2017) Yan-qin Yuan et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Recent developments in sulfur–carbon bond formation reaction involving thiosulfates

(2017) Zongjun Qiao et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Metal-free phosphonation of heteroarene N-oxides with trialkyl phosphite at room temperature

(2017) Ming-Tao Chen et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Nickel Phosphite/Phosphine-Catalyzed C–S Cross-Coupling of Aryl Chlorides and Thiols

(2017) Kieran D. Jones et al.   ORGANIC LETTERS

Iodine-Catalyzed Direct C–H Alkenylation of Azaheterocycle N-Oxides with Alkenes

(2017) Zhenhao Zhang et al.   ORGANIC LETTERS

Expedient C–H Chalcogenation of Indolines and Indoles by Positional-Selective Copper Catalysis

(2017) Parthasarathy Gandeepan et al.   ACS Catalysis

Iodine-Mediated Sulfonylation of Quinoline N -Oxides: a Mild and Metal-Free One-Pot Synthesis of 2-Sulfonyl Quinolines

(2017) Wen-Kai Fu et al.   Asian Journal of Organic Chemistry

Synthesis of Pyrazine-Thiazole Biheteroaryl Compounds through Base-Promoted Oxidative Cross-Dehydrogenative Coupling Reactions

(2017) Yuanyuan Shan et al.   Asian Journal of Organic Chemistry

Visible light-induced tandem oxidative cyclization of 2-alkynylanilines with disulfides (diselenides) to 3-sulfenyl- and 3-selenylindoles under transition metal-free and photocatalyst-free conditions

(2017) Qing Shi et al.   Organic Chemistry Frontiers

Transition-Metal-Free Regioselective Alkylation of Quinoline N-Oxides via Oxidative Alkyl Migration and C−C Bond Cleavage of tert-/sec-Alcohols

(2017) Chiranjit Sen et al.   ADVANCED SYNTHESIS & CATALYSIS

Metal-Free Thiolation of Imidazopyridines with Functionalized Haloalkanes Using Elemental Sulfur

(2017) Jun-Rong Zhang et al.   ADVANCED SYNTHESIS & CATALYSIS

Odorless, Regioselective Synthesis of Diaryl Sulfides and α-Thioaryl Carbonyls from Sodium Arylsulfinates via a Metal- Free Radical Strategy in Water

(2016) Ya-mei Lin et al.   ADVANCED SYNTHESIS & CATALYSIS

Iridium(III)-Catalyzed Direct CH Sulfonamidation of 2-Aryl-1,2,3-triazoleN-Oxides with Sulfonyl Azides

(2016) Bingfeng Zhu et al.   ADVANCED SYNTHESIS & CATALYSIS

Aerobic copper-catalyzed decarboxylative thiolation

(2016) Minghao Li et al.   CHEMICAL COMMUNICATIONS

Sulfur Containing Scaffolds in Drugs: Synthesis and Application in Medicinal Chemistry

(2016) Minghao Feng et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Catalyst-free thiolation of indoles with sulfonyl hydrazides for the synthesis of 3-sulfenylindoles in water

(2016) Yu Yang et al.   GREEN CHEMISTRY

Palladium-Catalyzed Oxidative Sulfenylation of Indoles and Related Electron-Rich Heteroarenes with Aryl Boronic Acids and Elemental Sulfur

(2016) Jianxiao Li et al.   JOURNAL OF ORGANIC CHEMISTRY

C2-Alkenylation of N-heteroaromatic compounds via Brønsted acid catalysis

(2016) Giacomo E. M. Crisenza et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Regioselective transition metal- and halogen-free direct dithiolation at C(sp3)–H of nitrotoluenes with diaryl disulfides

(2016) Shailesh Kumar et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Fast regioselective sulfonylation of pyridine/quinoline N-oxides induced by iodine

(2016) Ruijia Wang et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Generation of thioethers via direct C–H functionalization with sodium benzenesulfinate as a sulfur source

(2016) Yingcai Ding et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Cu-Catalyzed Deoxygenative C2-Sulfonylation Reaction of Quinoline N-Oxides with Sodium Sulfinate

(2016) Bingnan Du et al.   ORGANIC LETTERS

Synthesis of 2-Alkenylquinoline by Reductive Olefination of Quinoline N-Oxide under Metal-Free Conditions

(2016) Hong Xia et al.   ORGANIC LETTERS

Transition-Metal-Free Diarylannulated Sulfide and Selenide Construction via Radical/Anion-Mediated Sulfur–Iodine and Selenium–Iodine Exchange

(2016) Ming Wang et al.   ORGANIC LETTERS

Advances in transition-metal catalyzed thioetherification reactions of aromatic compounds

(2016) Arash Ghaderi   TETRAHEDRON

Heterogeneously Catalyzed Direct CH Thiolation of Heteroarenes

(2015) Suhelen Vásquez-Céspedes et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Palladium-catalyzed oxidative carbamoylation of isoquinoline N-oxides with formylamides by means of dual C–H oxidative coupling

(2015) Bo Yao et al.   CHEMICAL COMMUNICATIONS

H-phosphonate-mediated sulfonylation of heteroaromatic N-oxides: a mild and metal-free one-pot synthesis of 2-sulfonyl quinolines/pyridines

(2015) Kai Sun et al.   CHEMICAL COMMUNICATIONS

Recent advances in C–S bond formation via C–H bond functionalization and decarboxylation

(2015) Chao Shen et al.   CHEMICAL SOCIETY REVIEWS

Copper-Catalyzed Direct Sulfoximination of HeteroaromaticN-Oxides by Dual C−H/N−H Dehydrogenative Cross-Coupling

(2015) Hao Yu et al.   Chemistry-An Asian Journal

Iodine catalyzed cross-dehydrogenative C–S coupling by C(sp2)–H bond activation: direct access to aryl sulfides from aryl thiols

(2015) Santosh Kumar Reddy Parumala et al.   GREEN CHEMISTRY

Metal-Free Thiocyanation of Imidazoheterocycles through Visible Light Photoredox Catalysis

(2015) Shubhanjan Mitra et al.   JOURNAL OF ORGANIC CHEMISTRY

Pd-Catalyzed Direct C–H Bond Sulfonylation of Azobenzenes with Arylsulfonyl Chlorides

(2015) Duo Zhang et al.   JOURNAL OF ORGANIC CHEMISTRY

Iodine-catalyzed regioselective thiolation of imidazo[1,2-a]pyridines using sulfonyl hydrazides as a thiol surrogate

(2015) Avik Kumar Bagdi et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Base-Promoted Cross-Dehydrogenative Coupling of Quinoline N-Oxides with 1,3-Azoles

(2015) Xiaopei Chen et al.   ORGANIC LETTERS

Regioselective Metal-Free Cross-Coupling of Quinoline N-Oxides with Boronic Acids

(2015) Luis Bering et al.   ORGANIC LETTERS

Peroxide promoted metal-free thiolation of phosphites by thiophenols/disulfides

(2015) Jichao Wang et al.   TETRAHEDRON

Recent advances in the C–H-functionalization of the distal positions in pyridines and quinolines

(2015) David E. Stephens et al.   TETRAHEDRON

Transition-Metal-Catalyzed Site-Selective C–H Functionalization of Quinolines beyond C2 Selectivity

(2015) Tomohiro Iwai et al.   ACS Catalysis

The development of carbene-stabilized N–O radical coupling strategy in metal-free regioselective C–H azidation of quinoline N-oxides

(2015) Pan Li et al.   Organic Chemistry Frontiers

Transition metal-catalyzed C–H bond functionalizations by the use of diverse directing groups

(2015) Zhengkai Chen et al.   Organic Chemistry Frontiers

Recent Advances in Catalytic Functionalization ofN-Oxide CompoundsviaCH Bond Activation

(2014) Guobing Yan et al.   ADVANCED SYNTHESIS & CATALYSIS

Iodine-Catalyzed Regioselective Sulfenylation of Indoles with Sodium Sulfinates

(2014) Fuhong Xiao et al.   ADVANCED SYNTHESIS & CATALYSIS

Palladium-catalyzed thiolation of alkanes and ethers with arylsulfonyl hydrazides

(2014) Sheng-rong Guo et al.   CHEMICAL COMMUNICATIONS

Palladium-catalyzed oxidative CH/CH cross-coupling of pyridine N-oxides with five-membered heterocycles

(2014) Wei Liu et al.   CHEMICAL COMMUNICATIONS

Direct regioselective phosphonation of heteroaryl N-oxides with H-phosphonates under metal and external oxidant free conditions

(2014) Hui Wang et al.   CHEMICAL COMMUNICATIONS

1,3,4-Thiadiazole: Synthesis, Reactions, and Applications in Medicinal, Agricultural, and Materials Chemistry

(2014) Yang Hu et al.   CHEMICAL REVIEWS

Iodine-Mediated Thiolation of Substituted Naphthols/Naphthylamines and Arylsulfonyl Hydrazides via C(sp2)–H Bond Functionalization

(2014) Xing Kang et al.   JOURNAL OF ORGANIC CHEMISTRY

A Visible-Light-Promoted Aerobic Metal-Free C-3 Thiocyanation of Indoles

(2014) Weigang Fan et al.   JOURNAL OF ORGANIC CHEMISTRY

2-Alkynylbenzaldoxime: a versatile building block for the generation of N-heterocycles

(2014) Linman He et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Cu(II)-Mediated C–S/N–S Bond Formation via C–H Activation: Access to Benzoisothiazolones Using Elemental Sulfur

(2014) Fa-Jie Chen et al.   ORGANIC LETTERS

Direct, Catalytic, and Regioselective Synthesis of 2-Alkyl-, Aryl-, and Alkenyl-Substituted N-Heterocycles from N-Oxides

(2014) Oleg V. Larionov et al.   ORGANIC LETTERS

Copper-Catalyzed Direct Amination of Quinoline N-Oxides via C–H Bond Activation under Mild Conditions

(2014) Chongwei Zhu et al.   ORGANIC LETTERS

Rh(III)-Catalyzed Selenylation of Arenes with Selenenyl Chlorides/Diselenides via C–H Activation

(2014) Songjie Yu et al.   ORGANIC LETTERS

Copper-Catalyzed Synthesis of α-Trifluoromethylthio-Substituted Ketones

(2014) Yangjie Huang et al.   ORGANIC LETTERS

Recent advances in the synthesis of quinolines: a review

(2014) Shraddha M. Prajapati et al.   RSC Advances

Silver catalyzed decarboxylative acylation of pyridine-N-oxides using α-oxocarboxylic acids

(2014) Rajendran Suresh et al.   RSC Advances

Direct C-2 Alkylation of QuinolineN-Oxides with EthersviaPalladium-Catalyzed Dehydrogenative Cross-Coupling Reaction

(2013) Zhiyong Wu et al.   ADVANCED SYNTHESIS & CATALYSIS

Direct 2-acetoxylation of quinoline N-oxides via copper catalyzed C–H bond activation

(2013) Xuan Chen et al.   CHEMICAL COMMUNICATIONS

Recent advances in isocyanide insertion chemistry

(2013) Guanyinsheng Qiu et al.   CHEMICAL SOCIETY REVIEWS

Copper-Catalyzed CH Bond Direct Chalcogenation of Aromatic Compounds Leading to Diaryl Sulfides, Selenides, and Diselenides by Using Elemental Sulfur and Selenium as Chalcogen Sources Under Oxidative Conditions

(2013) Fumitoshi Shibahara et al.   Chemistry-An Asian Journal

K2CO3 promoted direct sulfenylation of indoles: a facile approach towards 3-sulfenylindoles

(2013) Peng Sang et al.   GREEN CHEMISTRY

Palladium-Catalyzed C–H Activation/Cross-Coupling of Pyridine N-Oxides with Nonactivated Secondary Alkyl Bromides

(2013) Bin Xiao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Copper-Catalyzed Intermolecular Dehydrogenative Amidation/Amination of Quinoline N-Oxides with Lactams/Cyclamines

(2013) Gang Li et al.   ORGANIC LETTERS

Pd-Catalyzed Oxidative CH/CH Direct Coupling of Heterocyclic N-Oxides

(2013) Wei Liu et al.   ORGANIC LETTERS

Sulfonylation of Quinoline N-Oxides with Aryl Sulfonyl Chlorides via Copper-Catalyzed C–H Bonds Activation

(2013) Zhiyong Wu et al.   ORGANIC LETTERS

Palladium-Catalyzed Olefination and Arylation of 2-Substituted 1,2,3-Triazole N-Oxides

(2013) Wei Liu et al.   ORGANIC LETTERS

Tetrahydrobiopterin Biosynthesis as an Off-Target of Sulfa Drugs

(2013) H. Haruki et al.   SCIENCE

A highly selective and sensitive near-infrared fluorescence probe for arylamine N-acetyltransferase 2 in vitro and in vivo

(2013) Xin Wang et al.   Chemical Science

A Metal-Free Sulfenylation and Bromosulfenylation of Indoles: Controllable Synthesis of 3-Arylthioindoles and 2-Bromo-3-arylthioindoles

(2012) Dayun Huang et al.   ADVANCED SYNTHESIS & CATALYSIS

An Air-Stable Copper Reagent for Nucleophilic Trifluoromethylthiolation of Aryl Halides

(2012) Zhiqiang Weng et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Versatile Rhodium(I) Catalyst System for the Addition of Heteroarenes to both Alkenes and Alkynes by a CH Bond Activation

(2012) Jaeyune Ryu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Copper-Catalyzed Oxidative Trifluoromethylthiolation of Aryl Boronic Acids with TMSCF3 and Elemental Sulfur

(2012) Chao Chen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Transition metal-free direct C–H bond thiolation of 1,3,4-oxadiazoles and related heteroarenes

(2012) Liang-Hua Zou et al.   CHEMICAL COMMUNICATIONS

Visible light-induced 3-sulfenylation of N-methylindoles with arylsulfonyl chlorides

(2012) Min Chen et al.   CHEMICAL COMMUNICATIONS

Synthesis of Pyridine and Dihydropyridine Derivatives by Regio- and Stereoselective Addition to N-Activated Pyridines

(2012) James A. Bull et al.   CHEMICAL REVIEWS

Transition-metal mediated carbon–sulfur bond activation and transformations

(2012) Liandi Wang et al.   CHEMICAL SOCIETY REVIEWS

Cu-Catalyzed Three-Component Synthesis of Substituted Benzothiazoles in Water

(2012) Hang Deng et al.   CHEMISTRY-A EUROPEAN JOURNAL

Iodine-catalyzed oxidative system for 3-sulfenylation of indoles with disulfides using DMSO as oxidant under ambient conditions in dimethyl carbonate

(2012) Wenlei Ge et al.   GREEN CHEMISTRY

Melanin-Concentrating Hormone Receptor 1 Antagonists. Synthesis and Structure–Activity Relationships of Novel 3-(Aminomethyl)quinolines

(2012) Makoto Kamata et al.   JOURNAL OF MEDICINAL CHEMISTRY

Metal-Free Oxidative Trifluoromethylthiolation of Terminal Alkynes with CF3SiMe3 and Elemental Sulfur

(2012) Chao Chen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Copper-Promoted Sulfenylation of sp2 C–H Bonds

(2012) Ly Dieu Tran et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Rhodium-Catalyzed Synthesis of Diaryl Sulfides Using Aryl Fluorides and Sulfur/Organopolysulfides

(2012) Mieko Arisawa et al.   ORGANIC LETTERS

Synthesis of di(hetero)aryl sulfides by directly using arylsulfonyl chlorides as a sulfur source

(2011) Qian Wu et al.   CHEMICAL COMMUNICATIONS

Carbon-Sulfur Bond Formation of Challenging Substrates at Low Temperature by Using Pd-PEPPSI-IPent

(2011) Mahmoud Sayah et al.   CHEMISTRY-A EUROPEAN JOURNAL

Synthesis of 2,4-Diiodoquinolines via the Photochemical Cyclization ofo-Alkynylaryl Isocyanides with Iodine

(2011) Takenori Mitamura et al.   JOURNAL OF ORGANIC CHEMISTRY

Ruthenium-Catalyzed Meta Sulfonation of 2-Phenylpyridines

(2011) Ourida Saidi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Molecular iodine-catalyzed and air-mediated tandem synthesis of quinolines via three-component reaction of amines, aldehydes, and alkynes

(2011) Xuejian Li et al.   TETRAHEDRON

Direct Azole Amination: CH Functionalization as a New Approach to Biologically Important Heterocycles

(2010) Alan Armstrong et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Microwave-assisted multicomponent domino cyclization–aromatization: an efficient approach for the synthesis of substituted quinolines

(2010) Aditya Kulkarni et al.   GREEN CHEMISTRY

Copper-Catalyzed Thiolation of the Di- or Trimethoxybenzene Arene C−H Bond with Disulfides

(2010) Shouhui Zhang et al.   JOURNAL OF ORGANIC CHEMISTRY

Palladium(II)-Catalyzed Oxidative C−H/C−H Cross-Coupling of Heteroarenes

(2010) Peihua Xi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Copper-Catalyzed Direct C Arylation of Heterocycles with Aryl Bromides: Discovery of Fluorescent Core Frameworks

(2009) Dongbing Zhao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis of CuO on mesoporous silica and its applications for coupling reactions of thiols with aryl iodides

(2009) Chin-Keng Chen et al.   CHEMICAL COMMUNICATIONS

Solvent-Free Heterocyclic Synthesis

(2009) Marcos A. P. Martins et al.   CHEMICAL REVIEWS

Synthesis of Heterocycles Mediated by Benzotriazole. 1. Monocyclic Systems

(2009) Alan R. Katritzky et al.   CHEMICAL REVIEWS

Antimalarial Benzylisoquinoline Alkaloid from the Rainforest TreeDoryphora sassafras

(2009) Malcolm S. Buchanan et al.   JOURNAL OF NATURAL PRODUCTS

Calothrixins, a New Class of Human DNA Topoisomerase I Poisons⊥

(2009) Qasim A. Khan et al.   JOURNAL OF NATURAL PRODUCTS

A Simple and Convenient Copper-Catalyzed Tandem Synthesis of Quinoline-2-carboxylates at Room Temperature

(2009) He Huang et al.   JOURNAL OF ORGANIC CHEMISTRY

Palladium-Catalyzed Direct Arylation of Azine and AzoleN-Oxides: Reaction Development, Scope and Applications in Synthesis

(2009) Louis-Charles Campeau et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Palladium-Catalyzed Alkenylation of Quinoline-N-oxides via C−H Activation under External-Oxidant-Free Conditions

(2009) Junliang Wu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Palladium-Catalyzed C−H Bond Functionalization with Arylsulfonyl Chlorides

(2009) Xiaodan Zhao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Silver-Mediated Synthesis of Heterocycles

(2008) Míriam Álvarez-Corral et al.   CHEMICAL REVIEWS

Biosynthesis of Aurachins A−L inStigmatella aurantiaca: A Feeding Study

(2008) Gerhard Höfle et al.   JOURNAL OF NATURAL PRODUCTS

Isolation and Biosynthesis of Aurachin P and 5-Nitroresorcinol fromStigmatella erecta

(2008) Gerhard Höfle et al.   JOURNAL OF NATURAL PRODUCTS

Palladium-Catalyzed C−H Functionalization of PyridineN-Oxides: Highly Selective Alkenylation and Direct Arylation with Unactivated Arenes

(2008) Seung Hwan Cho et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY