Clarithromycin Enhances the Antibacterial Activity and Wound Healing Capacity in Type 2 Diabetes Mellitus by Increasing LL-37 Load on Neutrophil Extracellular Traps

Dysfunctional Wound Healing in Diabetic Foot Ulcers: New Crossroads

(2018) Frank M. Davis et al.   Current Diabetes Reports

The Immunomodulatory Effects of Macrolides—A Systematic Review of the Underlying Mechanisms

(2018) Petra Zimmermann et al.   Frontiers in Immunology

Wound-Healing Peptides for Treatment of Chronic Diabetic Foot Ulcers and Other Infected Skin Injuries

(2017) Ana Gomes et al.   MOLECULES

NETopathies? Unraveling the Dark Side of Old Diseases through Neutrophils

(2017) Alexandros Mitsios et al.   Frontiers in Immunology

NETosis before and after Hyperglycemic Control in Type 2 Diabetes Mellitus Patients

(2017) Agostina Carestia et al.   PLoS One

The Effect of Short-Term Hyperglycemia on the Innate Immune System

(2016) Nagham Jafar et al.   AMERICAN JOURNAL OF THE MEDICAL SCIENCES

NETosis Delays Diabetic Wound Healing in Mice and Humans

(2016) Gian Paolo Fadini et al.   DIABETES

2. Classification and Diagnosis of Diabetes

(2016)   DIABETES CARE

LL37:DNA complexes provide antimicrobial activity against intracellular bacteria in human macrophages

(2016) Alexander Stephan et al.   IMMUNOLOGY

Circulating Neutrophil Extracellular Trap Levels in Well-Controlled Type 2 Diabetes and Pathway Involved in Their Formation Induced by High-Dose Glucose

(2016) Arina Miyoshi et al.   PATHOBIOLOGY

Gradient Infiltration of Neutrophil Extracellular Traps in Colon Cancer and Evidence for Their Involvement in Tumour Growth

(2016) Stella Arelaki et al.   PLoS One

Immunomodulatory Role of Clarithromycin in Acinetobacter baumannii Infection via Formation of Neutrophil Extracellular Traps

(2015) Theocharis Konstantinidis et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Expression of functional tissue factor by neutrophil extracellular traps in culprit artery of acute myocardial infarction

(2015) Dimitrios A. Stakos et al.   EUROPEAN HEART JOURNAL

Diabetes primes neutrophils to undergo NETosis, which impairs wound healing

(2015) Siu Ling Wong et al.   NATURE MEDICINE

Molecular mechanisms of NET formation and degradation revealed by intravital imaging in the liver vasculature

(2015) Elzbieta Kolaczkowska et al.   Nature Communications

NETosis is induced by high glucose and associated with type 2 diabetes

(2014) Lisa Menegazzo et al.   ACTA DIABETOLOGICA

Neutrophil extracellular traps regulate IL-1β-mediated inflammation in familial Mediterranean fever

(2014) Eirini Apostolidou et al.   ANNALS OF THE RHEUMATIC DISEASES

C5a and TNF-  Up-Regulate the Expression of Tissue Factor in Intra-Alveolar Neutrophils of Patients with the Acute Respiratory Distress Syndrome

(2014) K. Kambas et al.   JOURNAL OF IMMUNOLOGY

Neutrophil extracellular traps promote differentiation and function of fibroblasts

(2014) Akrivi Chrysanthopoulou et al.   JOURNAL OF PATHOLOGY

Tissue factor expression in neutrophil extracellular traps and neutrophil derived microparticles in antineutrophil cytoplasmic antibody associated vasculitis may promote thromboinflammation and the thrombophilic state associated with the disease

(2013) Konstantinos Kambas et al.   ANNALS OF THE RHEUMATIC DISEASES

High glucose modulates IL-6 mediated immune homeostasis through impeding neutrophil extracellular trap formation

(2013) Manjunath B. Joshi et al.   FEBS LETTERS

Little Peptide, Big Effects: The Role of LL-37 in Inflammation and Autoimmune Disease

(2013) J. M. Kahlenberg et al.   JOURNAL OF IMMUNOLOGY

Pathophysiology and treatment of type 2 diabetes: perspectives on the past, present, and future

(2013) Steven E Kahn et al.   LANCET

NETs Are a Source of Citrullinated Autoantigens and Stimulate Inflammatory Responses in Rheumatoid Arthritis

(2013) R. Khandpur et al.   Science Translational Medicine

Auto-Antigenic Protein-DNA Complexes Stimulate Plasmacytoid Dendritic Cells to Promote Atherosclerosis

(2012) Yvonne Döring et al.   CIRCULATION

Neutrophil Extracellular Traps Directly Induce Epithelial and Endothelial Cell Death: A Predominant Role of Histones

(2012) Mona Saffarzadeh et al.   PLoS One

Tissue factor-thrombin signaling enhances the fibrotic activity of myofibroblasts in systemic sclerosis through up-regulation of endothelin receptor A

(2011) Akrivi Chrysanthopoulou et al.   ARTHRITIS AND RHEUMATISM

Wound healing activity of the human antimicrobial peptide LL37

(2011) Reinaldo Ramos et al.   PEPTIDES

Neutrophil Extracellular Trap Formation Is Associated with IL-1β and Autophagy-Related Signaling in Gout

(2011) Ioannis Mitroulis et al.   PLoS One

Neutrophils Activate Plasmacytoid Dendritic Cells by Releasing Self-DNA-Peptide Complexes in Systemic Lupus Erythematosus

(2011) R. Lande et al.   Science Translational Medicine

Histone hypercitrullination mediates chromatin decondensation and neutrophil extracellular trap formation

(2009) Yanming Wang et al.   JOURNAL OF CELL BIOLOGY

In vitro and In vivo Wound Healing-Promoting Activities of Human Cathelicidin LL-37

(2007) Marta Carretero et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY