LL37:DNA complexes provide antimicrobial activity against intracellular bacteria in human macrophages

The responses of macrophages in interaction with neutrophils that undergo NETosis

(2016) Daigo Nakazawa et al.   JOURNAL OF AUTOIMMUNITY

Group A Streptococcal M1 Protein Sequesters Cathelicidin to Evade Innate Immune Killing

(2015) Christopher N. LaRock et al.   Cell Host & Microbe

Importance of Endosomal Cathelicidin Degradation To Enhance DNA-Induced Chicken Macrophage Activation

(2015) Maarten Coorens et al.   JOURNAL OF IMMUNOLOGY

P2X7Receptor Regulates Internalization of Antimicrobial Peptide LL-37 by Human Macrophages That Promotes Intracellular Pathogen Clearance

(2015) Xiao Tang et al.   JOURNAL OF IMMUNOLOGY

Extracellular traps and macrophages: new roles for the versatile phagocyte

(2015) Devin M. Boe et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Neutrophil extracellular traps license macrophages for cytokine production in atherosclerosis

(2015) A. Warnatsch et al.   SCIENCE

Differential activation of neutrophil extracellular traps by specific periodontal bacteria

(2014) Phillipa White et al.   FREE RADICAL BIOLOGY AND MEDICINE

LL-37 Peptide Enhancement of Signal Transduction by Toll-like Receptor 3 Is Regulated by pH

(2014) Divyendu Singh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Endogenous Intracellular Cathelicidin Enhances TLR9 Activation in Dendritic Cells and Macrophages

(2014) Yukinobu Nakagawa et al.   JOURNAL OF IMMUNOLOGY

Novel Role of the Antimicrobial Peptide LL-37 in the Protection of Neutrophil Extracellular Traps against Degradation by Bacterial Nucleases

(2014) Ariane Neumann et al.   Journal of Innate Immunity

Neutrophils sense microbe size and selectively release neutrophil extracellular traps in response to large pathogens

(2014) Nora Branzk et al.   NATURE IMMUNOLOGY

Mycobacterium tuberculosis ESAT-6 is a leukocidin causing Ca2+ influx, necrosis and neutrophil extracellular trap formation

(2014) R J Francis et al.   Cell Death & Disease

Direct uptake and degradation of DNA by lysosomes

(2013) Yuuki Fujiwara et al.   Autophagy

CD40 ligand and interferon-γ induce an antimicrobial response againstMycobacterium tuberculosisin human monocytes

(2013) Georgiana M. Klug-Micu et al.   IMMUNOLOGY

Macrophage Clearance of Neutrophil Extracellular Traps Is a Silent Process

(2013) C. Farrera et al.   JOURNAL OF IMMUNOLOGY

Mycobacterium tuberculosis-Induced Neutrophil Extracellular Traps Activate Human Macrophages

(2013) Clara Braian et al.   Journal of Innate Immunity

Vibrio cholerae Evades Neutrophil Extracellular Traps by the Activity of Two Extracellular Nucleases

(2013) Andrea Seper et al.   PLoS Pathogens

An Improved Strategy to Recover Large Fragments of Functional Human Neutrophil Extracellular Traps

(2013) Lorena Barrientos et al.   Frontiers in Immunology

Cytosolic sensing of extracellular self-DNA transported into monocytes by the antimicrobial peptide LL37

(2012) G. Chamilos et al.   BLOOD

A comprehensive summary of LL-37, the factotum human cathelicidin peptide

(2012) Dieter Vandamme et al.   CELLULAR IMMUNOLOGY

Neutrophil extracellular traps: Is immunity the second function of chromatin?

(2012) Volker Brinkmann et al.   JOURNAL OF CELL BIOLOGY

Neutrophil Extracellular Trap-Associated Protein Activation of the NLRP3 Inflammasome Is Enhanced in Lupus Macrophages

(2012) J. M. Kahlenberg et al.   JOURNAL OF IMMUNOLOGY

Azurophil Granule Proteins Constitute the Major Mycobactericidal Proteins in Human Neutrophils and Enhance the Killing of Mycobacteria in Macrophages

(2012) Prajna Jena et al.   PLoS One

Killing by neutrophil extracellular traps: fact or folklore?

(2011) R. Menegazzi et al.   BLOOD

Cathelicidin is involved in the intracellular killing of mycobacteria in macrophages

(2011) Avinash Sonawane et al.   CELLULAR MICROBIOLOGY

Netting Neutrophils Induce Endothelial Damage, Infiltrate Tissues, and Expose Immunostimulatory Molecules in Systemic Lupus Erythematosus

(2011) E. Villanueva et al.   JOURNAL OF IMMUNOLOGY

Myeloperoxidase associated with neutrophil extracellular traps is active and mediates bacterial killing in the presence of hydrogen peroxide

(2011) Heather Parker et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Rac2 is required for the formation of neutrophil extracellular traps

(2011) Michael Byung H. Lim et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Vitamin D Is Required for IFN- -Mediated Antimicrobial Activity of Human Macrophages

(2011) M. Fabri et al.   Science Translational Medicine

Neutrophils Activate Plasmacytoid Dendritic Cells by Releasing Self-DNA-Peptide Complexes in Systemic Lupus Erythematosus

(2011) R. Lande et al.   Science Translational Medicine

Netting Neutrophils Are Major Inducers of Type I IFN Production in Pediatric Systemic Lupus Erythematosus

(2011) G. S. Garcia-Romo et al.   Science Translational Medicine

Antimicrobial and Membrane Disrupting Activities of a Peptide Derived from the Human Cathelicidin Antimicrobial Peptide LL37

(2010) Sathiah Thennarasu et al.   BIOPHYSICAL JOURNAL

Neutrophil elastase and myeloperoxidase regulate the formation of neutrophil extracellular traps

(2010) Venizelos Papayannopoulos et al.   JOURNAL OF CELL BIOLOGY

T-cell cytokines differentially control human monocyte antimicrobial responses by regulating vitamin D metabolism

(2010) K. Edfeldt et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

M Protein and Hyaluronic Acid Capsule Are Essential for In Vivo Selection of covRS Mutations Characteristic of Invasive Serotype M1T1 Group A Streptococcus

(2010) J. N. Cole et al.   mBio

Neutrophil Extracellular Traps: How to Generate and Visualize Them

(2010) Volker Brinkmann et al.   Jove-Journal of Visualized Experiments

M1 Protein Allows Group A Streptococcal Survival in Phagocyte Extracellular Traps through Cathelicidin Inhibition

(2009) Xavier Lauth et al.   Journal of Innate Immunity

Neutrophil antimicrobial defense against Staphylococcus aureus is mediated by phagolysosomal but not extracellular trap-associated cathelicidin

(2009) Naja J. Jann et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Netting neutrophils in autoimmune small-vessel vasculitis

(2009) Kai Kessenbrock et al.   NATURE MEDICINE

Neutrophil Extracellular Traps Contain Calprotectin, a Cytosolic Protein Complex Involved in Host Defense against Candida albicans

(2009) Constantin F. Urban et al.   PLoS Pathogens

The Human Cathelicidin LL-37 Modulates the Activities of the P2X7Receptor in a Structure-dependent Manner

(2008) Linda Tomasinsig et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Neutrophil extracellular traps are induced by Mycobacterium tuberculosis

(2008) Victoria Ramos-Kichik et al.   TUBERCULOSIS

Ameobal Pathogen Mimivirus Infects Macrophages through Phagocytosis

(2008) Eric Ghigo et al.   PLoS Pathogens