PSD95 and nNOS interaction as a novel molecular target to modulate conditioned fear: relevance to PTSD

Regional Specific Modulation of Stress-Induced Neuronal Activation Associated with the PSD95/NOS Interaction Inhibitor ZL006 in the Wistar Kyoto Rat

(2017) Eoin Sherwin et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Source memory in rats is impaired by an NMDA receptor antagonist but not by PSD95-nNOS protein–protein interaction inhibitors

(2016) Alexandra E. Smith et al.   BEHAVIOURAL BRAIN RESEARCH

Small molecule inhibitors of PSD95-nNOS protein–protein interactions as novel analgesics

(2015) Wan-Hung Lee et al.   NEUROPHARMACOLOGY

Social learning and amygdala disruptions in Nf1 mice are rescued by blocking p21-activated kinase

(2014) Andrei I Molosh et al.   NATURE NEUROSCIENCE

How the amygdala affects emotional memory by altering brain network properties

(2014) Erno J. Hermans et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Small-molecule inhibitors at the PSD-95/nNOS interface attenuate MPP+-induced neuronal injury through Sirt3 mediated inhibition of mitochondrial dysfunction

(2014) Wei Hu et al.   NEUROCHEMISTRY INTERNATIONAL

Efficacy of Intravenous Ketamine for Treatment of Chronic Posttraumatic Stress Disorder

(2014) Adriana Feder et al.   JAMA Psychiatry

Neuronal nitric-oxide synthase deficiency impairs the long-term memory of olfactory fear learning and increases odor generalization

(2013) E. Pavesi et al.   LEARNING & MEMORY

Small-Molecule Inhibitors at the PSD-95/nNOS Interface have Antidepressant-Like Properties in Mice

(2013) Marika V Doucet et al.   NEUROPSYCHOPHARMACOLOGY

Molecular Mechanisms of Fear Learning and Memory

(2011) Joshua P. Johansen et al.   CELL

Pavlovian fear memory circuits and phenotype models of PTSD

(2011) Luke R. Johnson et al.   NEUROPHARMACOLOGY

Fear conditioning, synaptic plasticity and the amygdala: implications for posttraumatic stress disorder

(2011) Amy L. Mahan et al.   TRENDS IN NEUROSCIENCES

Effects of nitric oxide synthase inhibitors 1-(2-trifluoromethylphenyl) - imidazole (TRIM) and 7-nitroindazole (7-NI) on learning and memory in mice

(2010) Oguz Mutlu et al.   FUNDAMENTAL & CLINICAL PHARMACOLOGY

Treatment of cerebral ischemia by disrupting ischemia-induced interaction of nNOS with PSD-95

(2010) Li Zhou et al.   NATURE MEDICINE

Effects of the Nitric Oxide Synthase Inhibitor L-NAME on Recognition and Spatial Memory Deficits Produced by Different NMDA Receptor Antagonists in the Rat

(2010) Antonios Boultadakis et al.   NEUROPSYCHOPHARMACOLOGY

Plastic Synaptic Networks of the Amygdala for the Acquisition, Expression, and Extinction of Conditioned Fear

(2010) Hans-Christian Pape et al.   PHYSIOLOGICAL REVIEWS

Prelimbic cortical BDNF is required for memory of learned fear but not extinction or innate fear

(2010) D. C. Choi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Disruption of nNOS-PSD95 protein-protein interaction inhibits acute thermal hyperalgesia and chronic mechanical allodynia in rodents

(2009) SK Florio et al.   BRITISH JOURNAL OF PHARMACOLOGY

Ontogeny of Rat Recognition Memory measured by the novel object recognition task

(2009) Maxine L. Reger et al.   DEVELOPMENTAL PSYCHOBIOLOGY

Impairments in fear conditioning in mice lacking the nNOS gene

(2009) J. B. Kelley et al.   LEARNING & MEMORY

Neuronal nitric oxide synthase: Structure, subcellular localization, regulation, and clinical implications

(2009) Li Zhou et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

Effects of L-Arginine on 7-Nitroindazole-Induced Reference and Working Memory Performance of Rats

(2009) Füruzan Yildiz Akar et al.   PHARMACOLOGY

The NO-cGMP-PKG signaling pathway regulates synaptic plasticity and fear memory consolidation in the lateral amygdala via activation of ERK/MAP kinase

(2008) K. T. Ota et al.   LEARNING & MEMORY

Conditioning-strength dependent involvement of NMDA NR2B subtype receptor in the basolateral nucleus of amygdala in acquisition of auditory fear memory

(2008) Xue-Han Zhang et al.   NEUROPHARMACOLOGY

Adenosine A2A receptor blockade prevents memory dysfunction caused by β-amyloid peptides but not by scopolamine or MK-801

(2007) Geanne M.A. Cunha et al.   EXPERIMENTAL NEUROLOGY