Human T cell receptor occurrence patterns encode immune history, genetic background, and receptor specificity

MAIT cell clonal expansion and TCR repertoire shaping in human volunteers challenged with Salmonella Paratyphi A

(2018) Lauren J. Howson et al.   Nature Communications

High-throughput immune repertoire analysis with IGoR

(2018) Quentin Marcou et al.   Nature Communications

Method for identification of condition-associated public antigen receptor sequences

(2018) Mikhail V Pogorelyy et al.   eLife

Quantifiable predictive features define epitope-specific T cell receptor repertoires

(2017) Pradyot Dash et al.   NATURE

Identifying specificity groups in the T cell receptor repertoire

(2017) Jacob Glanville et al.   NATURE

Immunosequencing identifies signatures of cytomegalovirus exposure history and HLA-mediated effects on the T cell repertoire

(2017) Ryan O Emerson et al.   NATURE GENETICS

Broad TCR repertoire and diverse structural solutions for recognition of an immunodominant CD8+ T cell epitope

(2017) InYoung Song et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

VDJdb: a curated database of T-cell receptor sequences with known antigen specificity

(2017) Mikhail Shugay et al.   NUCLEIC ACIDS RESEARCH

Advanced Methodologies in High-Throughput Sequencing of Immune Repertoires

(2017) Simon Friedensohn et al.   TRENDS IN BIOTECHNOLOGY

Structural and regulatory diversity shape HLA-C protein expression levels

(2017) Gurman Kaur et al.   Nature Communications

Broad TCR repertoire and diverse structural solutions for recognition of an immunodominant CD8+ T cell epitope

(2017) InYoung Song et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Persisting fetal clonotypes influence the structure and overlap of adult human T cell receptor repertoires

(2017) Mikhail V. Pogorelyy et al.   PLoS Computational Biology

T cell receptor repertoires of mice and humans are clustered in similarity networks around conserved public CDR3 sequences

(2017) Asaf Madi et al.   eLife

Quantitative Characterization of the T Cell Receptor Repertoire of Naïve and Memory Subsets Using an Integrated Experimental and Computational Pipeline Which Is Robust, Economical, and Versatile

(2017) Theres Oakes et al.   Frontiers in Immunology

Genome-wide minor histocompatibility matching as related to the risk of graft-versus-host disease

(2016) Paul J. Martin et al.   BLOOD

Dynamics of Individual T Cell Repertoires: From Cord Blood to Centenarians

(2016) Olga V. Britanova et al.   JOURNAL OF IMMUNOLOGY

Genetic variation in MHC proteins is associated with T cell receptor expression biases

(2016) Eilon Sharon et al.   NATURE GENETICS

How structural adaptability exists alongside HLA-A2 bias in the human αβ TCR repertoire

(2016) Sydney J. Blevins et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Individual heritable differences result in unique cell lymphocyte receptor repertoires of naïve and antigen-experienced cells

(2016) Florian Rubelt et al.   Nature Communications

TCR  repertoire of CD4+ and CD8+ T cells is distinct in richness, distribution, and CDR3 amino acid composition

(2015) H. M. Li et al.   JOURNAL OF LEUKOCYTE BIOLOGY

T-cell receptor profiling in cancer

(2015) Ilan Kirsch et al.   Molecular Oncology

High-throughput pairing of T cell receptor α and β sequences

(2015) Bryan Howie et al.   Science Translational Medicine

Tracking global changes induced in the CD4 T-cell receptor repertoire by immunization with a complex antigen using short stretches of CDR3 protein sequence

(2014) Niclas Thomas et al.   BIOINFORMATICS

Next generation sequencing to determine HLA class II genotypes in a cohort of hematopoietic cell transplant patients and donors

(2014) Anajane G. Smith et al.   HUMAN IMMUNOLOGY

The IPD and IMGT/HLA database: allele variant databases

(2014) James Robinson et al.   NUCLEIC ACIDS RESEARCH

Specificity, promiscuity, and precursor frequency in immunoreceptors

(2013) Vanessa Venturi et al.   CURRENT OPINION IN IMMUNOLOGY

Estimating the ratio of CD4+ to CD8+ T cells using high-throughput sequence data

(2013) Ryan Emerson et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Asymmetric thymocyte death underlies the CD4:CD8 T-cell ratio in the adaptive immune system

(2013) C. Sinclair et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Using synthetic templates to design an unbiased multiplex PCR assay

(2013) Christopher S. Carlson et al.   Nature Communications

Determinants of public T cell responses

(2012) Hanjie Li et al.   CELL RESEARCH

MR1 presents microbial vitamin B metabolites to MAIT cells

(2012) Lars Kjer-Nielsen et al.   NATURE

Statistical inference of the generation probability of T-cell receptors from sequence repertoires

(2012) A. Murugan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural insights into the editing of germ-line-encoded interactions between T-cell receptor and MHC class II by V  CDR3

(2012) L. Deng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure of a TCR with high affinity for self-antigen reveals basis for escape from negative selection

(2011) Yiyuan Yin et al.   EMBO JOURNAL

The structure of superantigen complexed with TCR and MHC reveals novel insights into superantigenic T cell activation

(2010) Maria Saline et al.   Nature Communications

T Cell-Mediated Autoimmune Disease Due to Low-Affinity Crossreactivity to Common Microbial Peptides

(2009) Maria Harkiolaki et al.   IMMUNITY

T Cell Allorecognition via Molecular Mimicry

(2009) Whitney A. Macdonald et al.   IMMUNITY