Asymmetric thymocyte death underlies the CD4:CD8 T-cell ratio in the adaptive immune system

Comprehensive Assessment and Mathematical Modeling of T Cell Population Dynamics and Homeostasis

(2014) V. Thomas-Vaslin et al.   JOURNAL OF IMMUNOLOGY

Murine thymic selection quantified using a unique method to capture deleted T cells

(2013) G. L. Stritesky et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The BH3-Only Proteins Bim and Puma Cooperate to Impose Deletional Tolerance of Organ-Specific Antigens

(2012) Daniel H.D. Gray et al.   IMMUNITY

Maintenance of Peripheral Naive T Cells Is Sustained by Thymus Output in Mice but Not Humans

(2012) Ineke den Braber et al.   IMMUNITY

Reconciling views on T cell receptor germline bias for MHC

(2012) K. Christopher Garcia   TRENDS IN IMMUNOLOGY

MHC restriction is imposed on a diverse T cell receptor repertoire by CD4 and CD8 co-receptors during thymic selection

(2012) François Van Laethem et al.   TRENDS IN IMMUNOLOGY

The Long-Term Survival Potential of Mature T Lymphocytes Is Programmed During Development in the Thymus

(2011) C. Sinclair et al.   Science Signaling

The BCL-2 Family Reunion

(2010) Jerry E. Chipuk et al.   MOLECULAR CELL

Signaling by intrathymic cytokines, not T cell antigen receptors, specifies CD8 lineage choice and promotes the differentiation of cytotoxic-lineage T cells

(2010) Jung-Hyun Park et al.   NATURE IMMUNOLOGY

Regulation of Zap70 Expression During Thymocyte Development Enables Temporal Separation of CD4 and CD8 Repertoire Selection at Different Signaling Thresholds

(2010) M. Saini et al.   Science Signaling

Differential expression analysis for sequence count data

(2010) Simon Anders et al.   GENOME BIOLOGY

Bim-Mediated Apoptosis Is Not Necessary for Thymic Negative Selection to Ubiquitous Self-Antigens

(2009) Q. Hu et al.   JOURNAL OF IMMUNOLOGY

Distinct functions for the transcription factors GATA-3 and ThPOK during intrathymic differentiation of CD4+ T cells

(2008) Lie Wang et al.   NATURE IMMUNOLOGY

Mapping and quantifying mammalian transcriptomes by RNA-Seq

(2008) Ali Mortazavi et al.   NATURE METHODS