Tetrodotoxin: Chemistry, Toxicity, Source, Distribution and Detection

Public Health Response to Puffer Fish (Tetrodotoxin) Poisoning from Mislabeled Product

(2016) NICOLE J. COHEN et al.   JOURNAL OF FOOD PROTECTION

Development and single laboratory validation of an optical biosensor assay for tetrodotoxin detection as a tool to combat emerging risks in European seafood

(2013) Katrina Campbell et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

An Improved Synthesis of (−)-5,11-Dideoxytetrodotoxin

(2013) Masaatsu Adachi et al.   JOURNAL OF ORGANIC CHEMISTRY

Ion suppression; A critical review on causes, evaluation, prevention and applications

(2013) Ambrose Furey et al.   TALANTA

Removal of Toxin (Tetrodotoxin) from Puffer Ovary by Traditional Fermentation

(2013) Kensaku Anraku et al.   Toxins

Highly Toxic Ribbon Worm Cephalothrix simula Containing Tetrodotoxin in Hiroshima Bay, Hiroshima Prefecture, Japan

(2013) Manabu Asakawa et al.   Toxins

An improved competitive inhibition enzymatic immunoassay method for tetrodotoxin quantification

(2012) Amber N Stokes et al.   BIOLOGICAL PROCEDURES ONLINE

Comparison of sample preparation methods, validation of an UPLC–MS/MS procedure for the quantification of tetrodotoxin present in marine gastropods and analysis of pufferfish

(2012) Judith Kouassi Nzoughet et al.   FOOD CHEMISTRY

Depuration of Tetrodotoxin and Changes in Bacterial Communities in Pleurobranchea maculata Adults and Egg Masses Maintained in Captivity

(2012) Susanna A. Wood et al.   JOURNAL OF CHEMICAL ECOLOGY

Isolation and Structural Determination of the First 8-epi-type Tetrodotoxin Analogs from the Newt, Cynops ensicauda popei, and Comparison of Tetrodotoxin Analogs Profiles of This Newt and the Puffer Fish, Fugu poecilonotus

(2012) Yuta Kudo et al.   Marine Drugs

New Gastropod Vectors and Tetrodotoxin Potential Expansion in Temperate Waters of the Atlantic Ocean

(2012) Marisa Silva et al.   Marine Drugs

Screening for toxicity and resistance to paralytic shellfish toxin of shore crabs inhabiting at Leizhou peninsula, China

(2012) Huajuan Lin et al.   MARINE ENVIRONMENTAL RESEARCH

Tetrodotoxin does not protect red-spotted newts, Notophthalmus viridescens, from intestinal parasites

(2012) Dietrich Mebs et al.   TOXICON

Seasonality of brown recluse populations is reflected by numbers of brown recluse envenomations

(2012) R.K. Rader et al.   TOXICON

Microdistribution of tetrodotoxin in two species of blue-ringed octopuses (Hapalochlaena lunulata and Hapalochlaena fasciata) detected by fluorescent immunolabeling

(2012) Becky L. Williams et al.   TOXICON

On the occurrence of the silverstripe blaasop Lagocephalus sceleratus (Gmelin, 1789) along the Libyan coast

(2012) Marco Milazzo et al.   BioInvasions Records

First record of the Lessepsian migrant species Lagocephalus sceleratus (Gmelin, 1789) (Actinopterygii: Tetraodontidae) in the Central Mediterranean

(2012) Imed Jribi et al.   BioInvasions Records

On the origins and biosynthesis of tetrodotoxin

(2011) Rocky Chau et al.   AQUATIC TOXICOLOGY

Toxin composition and toxicity dynamics of marine gastropodNassariusspp. collected from Lianyungang, China

(2011) X. Luo et al.   Food Additives and Contaminants Part A-Chemistry Analysis Control Exposure & Risk Assessment

Liquid chromatography–mass spectrometry method to detect Tetrodotoxin and Its analogues in the puffer fish Lagocephalus sceleratus (Gmelin, 1789) from European waters

(2011) Paula Rodríguez et al.   FOOD CHEMISTRY

Determination and validation of tetrodotoxin in human whole blood using hydrophilic interaction liquid chromatography–tandem mass spectroscopy and its application

(2011) Hwang Eui Cho et al.   FORENSIC SCIENCE INTERNATIONAL

Analytical Challenges: Determination of Tetrodotoxin in Human Urine and Plasma by LC-MS/MS

(2011) Kelvin Sze-Yin Leung et al.   Marine Drugs

Separation, identification and quantification of tetrodotoxin and its analogs by LC–MS without calibration of individual analogs

(2011) Xiao-Wu Chen et al.   TOXICON

Tetrodotoxin levels in larval and metamorphosed newts (Taricha granulosa) and palatability to predatory dragonflies

(2011) Brian G. Gall et al.   TOXICON

Transfer profile of intramuscularly administered tetrodotoxin to artificial hybrid specimens of pufferfish, Takifugu rubripes and Takifugu niphobles

(2011) Junjie Wang et al.   TOXICON

Variability of tetrodotoxin and of its analogues in the red-spotted newt, Notophthalmus viridescens (Amphibia: Urodela: Salamandridae)

(2011) Mari Yotsu-Yamashita et al.   TOXICON

Toxic Marine Puffer Fish in Thailand Seas and Tetrodotoxin They Contained

(2011) Monrat Chulanetra et al.   Toxins

Tetrodotoxin Detection by a Surface Plasmon Resonance Sensor in Pufferfish Matrices and Urine

(2011) Allen D. Taylor et al.   Journal of Sensors

Multiple Outbreaks of Puffer Fish Intoxication in Bangladesh, 2008

(2010) Nusrat Homaira et al.   AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE

Synthesis of13C-Labeled 5,6,11-Trideoxytetrodotoxin

(2010) Taiki Umezawa et al.   CHEMISTRY LETTERS

Optimization of simultaneous analysis of tetrodotoxin, 4-epitetrodotoxin, 4,9-anhydrotetrodotoxin, and 5,6,11-trideoxytetrodotoxin by hydrophilic interaction liquid chromatography–tandem mass spectrometry

(2010) Mari Yotsu-Yamashita et al.   Forensic Toxicology

Evaluation of Surface Plasmon Resonance Biosensors for Detection of Tetrodotoxin in Food Matrices and Comparison to Analytical Methods

(2010) Betsy Jean Yakes et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Ontogeny of Tetrodotoxin Levels in Blue-ringed Octopuses: Maternal Investment and Apparent Independent Production in Offspring of Hapalochlaena lunulata

(2010) Becky L. Williams et al.   JOURNAL OF CHEMICAL ECOLOGY

Liquid chromatography–mass spectrometry in food safety

(2010) Ashok Kumar Malik et al.   JOURNAL OF CHROMATOGRAPHY A

Screening of tetrodotoxin in puffers using gas chromatography–mass spectrometry

(2010) Che Nin Man et al.   JOURNAL OF CHROMATOGRAPHY A

The Chemical and Evolutionary Ecology of Tetrodotoxin (TTX) Toxicity in Terrestrial Vertebrates

(2010) Charles T. Hanifin   Marine Drugs

Effects of Tetrodotoxin on the Mammalian Cardiovascular System

(2010) Thomas Zimmer   Marine Drugs

LC/MS Analysis of Tetrodotoxin and Its Deoxy Analogs in the Marine Puffer Fish Fugu niphobles from the Southern Coast of Korea, and in the Brackishwater Puffer Fishes Tetraodon nigroviridis and Tetraodon biocellatus from Southeast Asia

(2010) Jun-Ho Jang et al.   Marine Drugs

Behavioral and Chemical Ecology of Marine Organisms with Respect to Tetrodotoxin

(2010) Becky L. Williams   Marine Drugs

Development and validation of a high-throughput double solid phase extraction–liquid chromatography–tandem mass spectrometry method for the determination of tetrodotoxin in human urine and plasma

(2010) Bonnie Mei-Wah Fong et al.   TALANTA

Tissue distribution of tetrodotoxin in the red-spotted newt Notophthalmus viridescens

(2010) Dietrich Mebs et al.   TOXICON

A novel TTX-producing Aeromonas isolated from the ovary of Takifugu obscurus

(2010) Guimei Yang et al.   TOXICON

Detection of tetrodotoxin from the grey side-gilled sea slug - Pleurobranchaea maculata, and associated dog neurotoxicosis on beaches adjacent to the Hauraki Gulf, Auckland, New Zealand

(2010) Paul McNabb et al.   TOXICON

Tetrodotoxin: a potent marine toxin

(2010) Mongi Saoudi et al.   Toxin Reviews

Puffer fish poisoning in Bangladesh: clinical and toxicological results from large outbreaks in 2008

(2010) Q.T. Islam et al.   TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE

Isolation and characterization of a Bacillus species capable of producing tetrodotoxin from the puffer fish Fugu obscurus

(2010) Jun Wang et al.   WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY

Tetrodotoxin reduces cue-induced drug craving and anxiety in abstinent heroin addicts

(2009) Jie Shi et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Climate Change and the Potential Spreading of Marine Mucilage and Microbial Pathogens in the Mediterranean Sea

(2009) Roberto Danovaro et al.   PLoS One

First report on toxicity assessment of the Lessepsian migrant pufferfish Lagocephalus sceleratus (Gmelin, 1789) from European waters (Aegean Sea, Greece)

(2009) Panagiota Katikou et al.   TOXICON

Intra-organismal distribution of tetrodotoxin in two species of blue-ringed octopuses (Hapalochlaena fasciata and H. lunulata)

(2009) Becky L. Williams et al.   TOXICON

First report of TTX in a European trumpet shell

(2008) Laura Cassiday   ANALYTICAL CHEMISTRY

First Toxicity Report of Tetrodotoxin and 5,6,11-TrideoxyTTX in the Trumpet Shell Charonia lampas lampas in Europe

(2008) Paula Rodriguez et al.   ANALYTICAL CHEMISTRY

Uptake of paralytic shellfish poisoning and spirolide toxins by paddle crabs (Ovalipes catharus) via a bivalve vector

(2008) Rozalind Jester et al.   HARMFUL ALGAE

Tetrodotoxin poisoning evidenced by solid-phase extraction combining with liquid chromatography–tandem mass spectrometry

(2008) Hsiao-Chin Jen et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Stereoselective and Efficient Total Synthesis of Optically Active Tetrodotoxin fromd-Glucose

(2008) Ken-ichi Sato et al.   JOURNAL OF ORGANIC CHEMISTRY

Tetrodotoxin for Moderate to Severe Cancer Pain: A Randomized, Double Blind, Parallel Design Multicenter Study

(2008) Neil A. Hagen et al.   JOURNAL OF PAIN AND SYMPTOM MANAGEMENT

Tetrodotoxin – Distribution and Accumulation in Aquatic Organisms, and Cases of Human Intoxication

(2008) Tamao Noguchi   Marine Drugs

Symbiotic diversity in marine animals: the art of harnessing chemosynthesis

(2008) Nicole Dubilier et al.   NATURE REVIEWS MICROBIOLOGY

Identification and quantification of tetrodotoxin in the marine gastropod Nassarius by LC–MS

(2008) Hong-Nan Huang et al.   TOXICON

Examination of transformation among tetrodotoxin and its analogs in the living cultured juvenile puffer fish, kusafugu, Fugu niphobles by intramuscular administration

(2008) Michiko Kono et al.   TOXICON

Accumulation of tetrodotoxin and 4,9-anhydrotetrodotoxin in cultured juvenile kusafugu Fugu niphobles by dietary administration of natural toxic komonfugu Fugu poecilonotus liver

(2008) Michiko Kono et al.   TOXICON

Lessepsian migration and tetrodotoxin poisoning due to Lagocephalus sceleratus in the eastern Mediterranean

(2008) Yedidia Bentur et al.   TOXICON

Toxin-screening and identification of bacteria isolated from highly toxic marine gastropod Nassarius semiplicatus

(2008) Xiao-Jie Wang et al.   TOXICON

Concentrations of Saxitoxin and Tetrodotoxin in Three Species of Puffers from the Indian River Lagoon, Florida, the Location for Multiple Cases of Saxitoxin Puffer Poisoning from 2002 to 2004

(2008) Jonathan R. Deeds et al.   TRANSACTIONS OF THE AMERICAN FISHERIES SOCIETY

Two critical residues in p-loop regions of puffer fish Na+ channels on TTX sensitivity

(2007) Satoshi Maruta et al.   TOXICON

Occurrence of paralytic shellfish toxins in Cambodian Mekong pufferfish Tetraodon turgidus: Selective toxin accumulation in the skin

(2007) Laymithuna Ngy et al.   TOXICON