The role of AST-120 and protein-bound uremic toxins in irritable bowel syndrome: a therapeutic perspective

Irritable bowel syndrome: A clinical review

(2014) Rosa LS Soares   WORLD JOURNAL OF GASTROENTEROLOGY

Long-Term Effects of the Oral Adsorbent, AST-120, in Patients with Chronic Renal Failure

(2013) K Maeda et al.   JOURNAL OF INTERNATIONAL MEDICAL RESEARCH

p -Cresyl sulfate causes renal tubular cell damage by inducing oxidative stress by activation of NADPH oxidase

(2013) Hiroshi Watanabe et al.   KIDNEY INTERNATIONAL

Serotonin and serotonin transporter in the rectum of patients with irritable bowel disease

(2013) MAGDY EL-SALHY et al.   Molecular Medicine Reports

Review article: associations between immune activation, intestinal permeability and the irritable bowel syndrome

(2012) J. Matricon et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Indoxyl sulfate promotes vascular smooth muscle cell senescence with upregulation of p53, p21, and prelamin A through oxidative stress

(2012) Gulinuer Muteliefu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Randomised clinical trial: the safety and efficacy of AST-120 in non-constipating irritable bowel syndrome - a double-blind, placebo-controlled study

(2011) J. F. Tack et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Combination of Allergic Factors Can Worsen Diarrheic Irritable Bowel Syndrome: Role of Barrier Defects and Mast Cells

(2011) M Vivinus-Nébot et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Effects of AST-120 on Left Ventricular Mass in Predialysis Patients

(2011) Kentaro Nakai et al.   AMERICAN JOURNAL OF NEPHROLOGY

Brain-Gut Axis

(2011) Michael Camilleri et al.   JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION

The uremic solute indoxyl sulfate acts as an antioxidant against superoxide anion radicals under normal-physiological conditions

(2010) Yohei Miyamoto et al.   FEBS LETTERS

NADPH oxidase 4 mediates TGF-β-induced smooth muscle α-actin via p38MAPK and serum response factor

(2010) Abel Martin-Garrido et al.   FREE RADICAL BIOLOGY AND MEDICINE

Indoxyl Sulfate Induces Leukocyte-Endothelial Interactions through Up-regulation of E-selectin

(2010) Shunsuke Ito et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Oral adsorbent AST-120 ameliorates tubular injury in chronic renal failure patients by reducing proteinuria and oxidative stress generation

(2010) Tsukasa Nakamura et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Effects of an oral adsorbent on oxidative stress and fibronectin expression in experimental diabetic nephropathy

(2010) S. H. Lee et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

The Uremic Retention Solute p-Cresyl Sulfate and Markers of Endothelial Damage

(2009) Björn K.I. Meijers et al.   AMERICAN JOURNAL OF KIDNEY DISEASES

Effect of a Carbonaceous Oral Adsorbent on the Progression of CKD: A Multicenter, Randomized, Controlled Trial

(2009) Tadao Akizawa et al.   AMERICAN JOURNAL OF KIDNEY DISEASES

An Oral Sorbent, AST-120, Increases Klotho Expression and Inhibits Cell Senescence in the Kidney of Uremic Rats

(2009) Ayinuer Adijiang et al.   AMERICAN JOURNAL OF NEPHROLOGY

The Bile Acid Receptor FXR Is a Modulator of Intestinal Innate Immunity

(2009) P. Vavassori et al.   JOURNAL OF IMMUNOLOGY

Uremic toxins originating from colonic microbial metabolism

(2009) Pieter Evenepoel et al.   KIDNEY INTERNATIONAL

Oral charcoal adsorbent (AST-120) prevents progression of cardiac damage in chronic kidney disease through suppression of oxidative stress

(2009) H. Fujii et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

AST-120 (Kremezin®) initiated in early stage chronic kidney disease stunts the progression of renal dysfunction in type 2 diabetic subjects

(2008) Kazunori Konishi et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

Intestinal barrier dysfunction in inflammatory bowel diseases

(2008) Michael A. McGuckin et al.   INFLAMMATORY BOWEL DISEASES

Fatty acid-binding proteins: role in metabolic diseases and potential as drug targets

(2008) Masato Furuhashi et al.   NATURE REVIEWS DRUG DISCOVERY

Indoxyl sulphate promotes aortic calcification with expression of osteoblast-specific proteins in hypertensive rats

(2008) A. Adijiang et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

AST-120 Treatment in Pre-Dialysis Period Affects the Prognosis in Patients on Hemodialysis

(2008) Haruhiko Ueda et al.   RENAL FAILURE