NLRP6 negatively regulates pulmonary host defense in Gram-positive bacterial infection through modulating neutrophil recruitment and function

Intestinal epithelial Caspase-8 signaling is essential to prevent necroptosis during Salmonella Typhimurium induced enteritis

(2018) Manuela Hefele et al.   Mucosal Immunology

Nlrp6- and ASC-Dependent Inflammasomes Do Not Shape the Commensal Gut Microbiota Composition

(2017) Michail Mamantopoulos et al.   IMMUNITY

The NLR Protein NLRP6 Does Not Impact Gut Microbiota Composition

(2017) Paul Lemire et al.   Cell Reports

HMGB1, IL-1α, IL-33 and S100 proteins: dual-function alarmins

(2016) Damien Bertheloot et al.   Cellular & Molecular Immunology

Role of Interleukin-12 in Protection against Pulmonary Infection with Methicillin-Resistant Staphylococcus aureus

(2015) Quang-Tam Nguyen et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Microbiota-Modulated Metabolites Shape the Intestinal Microenvironment by Regulating NLRP6 Inflammasome Signaling

(2015) Maayan Levy et al.   CELL

Gasdermin D is an executor of pyroptosis and required for interleukin-1β secretion

(2015) Wan-ting He et al.   CELL RESEARCH

The gut microbiome in health and in disease

(2015) Andrew B. Shreiner et al.   CURRENT OPINION IN GASTROENTEROLOGY

Interferon-γenhances both the anti-bacterial and the pro-inflammatory response of human mast cells toStaphylococcus aureus

(2015) Emily J. Swindle et al.   IMMUNOLOGY

Reactive oxygen species-mediated bacterial killing by B lymphocytes

(2015) IstvÁn Kovács et al.   JOURNAL OF LEUKOCYTE BIOLOGY

NLRP12 modulates host defense through IL-17A–CXCL1 axis

(2015) S Cai et al.   Mucosal Immunology

IFN-γ induction by neutrophil-derived IL-17A homodimer augments pulmonary antibacterial defense

(2015) S Cai et al.   Mucosal Immunology

Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death

(2015) Jianjin Shi et al.   NATURE

Pore-Forming Toxins Induce Macrophage Necroptosis during Acute Bacterial Pneumonia

(2015) Norberto González-Juarbe et al.   PLoS Pathogens

Toxin-Induced Necroptosis Is a Major Mechanism of Staphylococcus aureus Lung Damage

(2015) Kipyegon Kitur et al.   PLoS Pathogens

NLRP6 Inflammasome Orchestrates the Colonic Host-Microbial Interface by Regulating Goblet Cell Mucus Secretion

(2014) Marta Wlodarska et al.   CELL

The activating effect of IFN-γ on monocytes/macrophages is regulated by the LIF–trophoblast–IL-10 axis via Stat1 inhibition and Stat3 activation

(2014) Angham Dallagi et al.   Cellular & Molecular Immunology

CD4+ T Cells Promote the Pathogenesis of Staphylococcus aureus Pneumonia

(2014) Dane Parker et al.   JOURNAL OF INFECTIOUS DISEASES

Fusobacterium nucleatum Potentiates Intestinal Tumorigenesis and Modulates the Tumor-Immune Microenvironment

(2013) Aleksandar D. Kostic et al.   Cell Host & Microbe

Methicillin-Resistant Staphylococcus aureus Therapy: Past, Present, and Future

(2013) K. A. Rodvold et al.   CLINICAL INFECTIOUS DISEASES

Gut metagenome in European women with normal, impaired and diabetic glucose control

(2013) Fredrik H. Karlsson et al.   NATURE

Widespread Mitochondrial Depletion via Mitophagy Does Not Compromise Necroptosis

(2013) Stephen W.G. Tait et al.   Cell Reports

Expansion of intestinal Prevotella copri correlates with enhanced susceptibility to arthritis

(2013) Jose U Scher et al.   eLife

Mixed Lineage Kinase Domain-like Protein Mediates Necrosis Signaling Downstream of RIP3 Kinase

(2012) Liming Sun et al.   CELL

Intrapulmonary Administration of Leukotriene B4 Augments Neutrophil Accumulation and Responses in the Lung to Klebsiella Infection in CXCL1 Knockout Mice

(2012) S. Batra et al.   JOURNAL OF IMMUNOLOGY

Staphylococcus aureus α-Hemolysin Mediates Virulence in a Murine Model of Severe Pneumonia Through Activation of the NLRP3 Inflammasome

(2012) Chahnaz Kebaier et al.   JOURNAL OF INFECTIOUS DISEASES

NLRP6 negatively regulates innate immunity and host defence against bacterial pathogens

(2012) Paras K. Anand et al.   NATURE

NLRP6 Inflammasome Regulates Colonic Microbial Ecology and Risk for Colitis

(2011) Eran Elinav et al.   CELL

A Functional Role for Nlrp6 in Intestinal Inflammation and Tumorigenesis

(2011) G. Y. Chen et al.   JOURNAL OF IMMUNOLOGY

NADPH-oxidase but not inducible nitric oxide synthase contributes to resistance in a murine Staphylococcus aureus Newman pneumonia model

(2011) Jens Köhler et al.   MICROBES AND INFECTION

Nod-like receptor pyrin domain-containing protein 6 (NLRP6) controls epithelial self-renewal and colorectal carcinogenesis upon injury

(2011) S. Normand et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neutrophils in innate host defense against Staphylococcus aureus infections

(2011) Kevin M. Rigby et al.   Seminars in Immunopathology

CXCL1 Regulates Pulmonary Host Defense to Klebsiella Infection via CXCL2, CXCL5, NF- B, and MAPKs

(2010) S. Cai et al.   JOURNAL OF IMMUNOLOGY

Neutrophil IL-10 suppresses peritoneal inflammatory monocytes during polymicrobial sepsis

(2010) Lee M. Ocuin et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Community-associated meticillin-resistant Staphylococcus aureus

(2010) Frank R DeLeo et al.   LANCET

Caspase-1-induced pyroptosis is an innate immune effector mechanism against intracellular bacteria

(2010) Edward A Miao et al.   NATURE IMMUNOLOGY

Receptor Interacting Protein Kinase-3 Determines Cellular Necrotic Response to TNF-α

(2009) Sudan He et al.   CELL

Type I IFNs mediate development of postinfluenza bacterial pneumonia in mice

(2009) Arash Shahangian et al.   JOURNAL OF CLINICAL INVESTIGATION

Staphylococcus aureus α-Hemolysin Activates the NLRP3-Inflammasome in Human and Mouse Monocytic Cells

(2009) Robin R. Craven et al.   PLoS One

A synergistic interferon-γ production is induced by mouse hepatitis virus in interleukin-12 (IL-12)/IL-18-activated natural killer cells and modulated by carcinoembryonic antigen-related cell adhesion molecules (CEACAM) 1a receptor

(2008) Alexandre Jacques et al.   IMMUNOLOGY

Neutrophil Depletion Causes a Fatal Defect in Murine Pulmonary Staphylococcus aureus clearance

(2008) Charles M. Robertson et al.   JOURNAL OF SURGICAL RESEARCH