Staphylococcus aureus α-Hemolysin Mediates Virulence in a Murine Model of Severe Pneumonia Through Activation of the NLRP3 Inflammasome

Glyburide Is Anti-inflammatory and Associated with Reduced Mortality in Melioidosis

(2011) Gavin C. K. W. Koh et al.   CLINICAL INFECTIOUS DISEASES

A Staphylococcus aureus pore-forming toxin subverts the activity of ADAM10 to cause lethal infection in mice

(2011) Ichiro Inoshima et al.   NATURE MEDICINE

Staphylococcus aureus Evades Lysozyme-Based Peptidoglycan Digestion that Links Phagocytosis, Inflammasome Activation, and IL-1β Secretion

(2010) Takahiro Shimada et al.   Cell Host & Microbe

Specificity for Human Hemoglobin Enhances Staphylococcus aureus Infection

(2010) Gleb Pishchany et al.   Cell Host & Microbe

Cytotoxins of the human pathogen Aeromonas hydrophila trigger, via the NLRP3 inflammasome, caspase-1 activation in macrophages

(2010) Andrea J. McCoy et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Pathogenic Vibrio Activate NLRP3 Inflammasome via Cytotoxins and TLR/Nucleotide-Binding Oligomerization Domain-Mediated NF- B Signaling

(2010) C. Toma et al.   JOURNAL OF IMMUNOLOGY

Community-associated methicillin-resistant Staphylococcus aureus immune evasion and virulence

(2010) Shawna F. Graves et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Contribution of NOD2 to lung inflammation during Staphylococcus aureus-induced pneumonia

(2010) Ronan Kapetanovic et al.   MICROBES AND INFECTION

Identification of a Novel Staphylococcus aureus Two-Component Leukotoxin Using Cell Surface Proteomics

(2010) Christy L. Ventura et al.   PLoS One

Role of a disintegrin and metalloprotease 10 in Staphylococcus aureus  -hemolysin-mediated cellular injury

(2010) G. A. Wilke et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

How the Noninflammasome NLRs Function in the Innate Immune System

(2010) J. P. Y. Ting et al.   SCIENCE

Pneumolysin Activates the NLRP3 Inflammasome and Promotes Proinflammatory Cytokines Independently of TLR4

(2010) Edel A. McNeela et al.   PLoS Pathogens

Prevention and Treatment of Staphylococcus aureus Pneumonia with a  -Cyclodextrin Derivative

(2009) B. E. Ragle et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Critical Role of NOD2 in Regulating the Immune Response to Staphylococcus aureus

(2009) H. S. Deshmukh et al.   INFECTION AND IMMUNITY

Anti-Alpha-Hemolysin Monoclonal Antibodies Mediate Protection against Staphylococcus aureus Pneumonia

(2009) B. E. Ragle et al.   INFECTION AND IMMUNITY

Therapy of autoinflammatory syndromes

(2009) Hal M. Hoffman   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Glyburide inhibits the Cryopyrin/Nalp3 inflammasome

(2009) Mohamed Lamkanfi et al.   JOURNAL OF CELL BIOLOGY

A Critical Role for Hemolysins and Bacterial Lipoproteins in Staphylococcus aureus-Induced Activation of the Nlrp3 Inflammasome

(2009) R. Munoz-Planillo et al.   JOURNAL OF IMMUNOLOGY

Staphylococcus aureus α-Hemolysin Activates the NLRP3-Inflammasome in Human and Mouse Monocytic Cells

(2009) Robin R. Craven et al.   PLoS One

NOD2 contributes to cutaneous defense against Staphylococcus aureus through  -toxin-dependent innate immune activation

(2009) P. Hruz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Efficacy and safety of rilonacept (interleukin-1 trap) in patients with cryopyrin-associated periodic syndromes: Results from two sequential placebo-controlled studies

(2008) Hal M. Hoffman et al.   ARTHRITIS AND RHEUMATISM

Vaccine protection againstStaphylococcus aureuspneumonia

(2008) Juliane Bubeck Wardenburg et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The role of virulence determinants in community-associated MRSA pathogenesis

(2008) Binh An Diep et al.   TRENDS IN MICROBIOLOGY