Initiation of ART during Early Acute HIV Infection Preserves Mucosal Th17 Function and Reverses HIV-Related Immune Activation
出版年份 2014 全文链接
标题
Initiation of ART during Early Acute HIV Infection Preserves Mucosal Th17 Function and Reverses HIV-Related Immune Activation
作者
关键词
Colon, HIV, HIV infections, Cytotoxic T cells, Immune activation, T cells, Blood, Cell staining
出版物
PLoS Pathogens
Volume 10, Issue 12, Pages e1004543
出版商
Public Library of Science (PLoS)
发表日期
2014-12-12
DOI
10.1371/journal.ppat.1004543
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Microbial Translocation in the Pathogenesis of HIV Infection and AIDS
- (2013) Giulia Marchetti et al. CLINICAL MICROBIOLOGY REVIEWS
- Mucosal immunology of HIV infection
- (2013) Huanbin Xu et al. IMMUNOLOGICAL REVIEWS
- Immune interventions in HIV infection
- (2013) Guislaine Carcelain et al. IMMUNOLOGICAL REVIEWS
- Mucosal Th17 Cell Function Is Altered during HIV Infection and Is an Independent Predictor of Systemic Immune Activation
- (2013) C. J. Kim et al. JOURNAL OF IMMUNOLOGY
- Antiretroviral Therapy Initiated Within 6 Months of HIV Infection Is Associated With Lower T-Cell Activation and Smaller HIV Reservoir Size
- (2013) Vivek Jain et al. JOURNAL OF INFECTIOUS DISEASES
- Molecular Evolution of the HIV-1 Thai Epidemic between the Time of RV144 Immunogen Selection to the Execution of the Vaccine Efficacy Trial
- (2013) G. H. Kijak et al. JOURNAL OF VIROLOGY
- Barriers to a cure for HIV: new ways to target and eradicate HIV-1 reservoirs
- (2013) Christine Katlama et al. LANCET
- Cell death by pyroptosis drives CD4 T-cell depletion in HIV-1 infection
- (2013) Gilad Doitsh et al. NATURE
- The split personality of regulatory T cells in HIV infection
- (2012) M. F. Chevalier et al. BLOOD
- Differential infection patterns of CD4+ T cells and lymphoid tissue viral burden distinguish progressive and nonprogressive lentiviral infections
- (2012) J. M. Brenchley et al. BLOOD
- Microbial translocation in HIV infection: causes, consequences and treatment opportunities
- (2012) Netanya G. Sandler et al. NATURE REVIEWS MICROBIOLOGY
- Impact of Multi-Targeted Antiretroviral Treatment on Gut T Cell Depletion and HIV Reservoir Seeding during Acute HIV Infection
- (2012) Jintanat Ananworanich et al. PLoS One
- Impact of CD8+ T-cell activation on CD4+ T-cell recovery and mortality in HIV-infected Ugandans initiating antiretroviral therapy
- (2011) Peter W. Hunt et al. AIDS
- Sigmoid Th17 populations, the HIV latent reservoir, and microbial translocation in men on long-term antiretroviral therapy
- (2011) Duncan Chege et al. AIDS
- Higher Levels of CRP, D-dimer, IL-6, and Hyaluronic Acid Before Initiation of Antiretroviral Therapy (ART) Are Associated With Increased Risk of AIDS or Death
- (2011) David R. Boulware et al. JOURNAL OF INFECTIOUS DISEASES
- Plasma Levels of Soluble CD14 Independently Predict Mortality in HIV Infection
- (2011) Netanya G. Sandler et al. JOURNAL OF INFECTIOUS DISEASES
- Increased Frequency of Regulatory T Cells Accompanies Increased Immune Activation in Rectal Mucosae of HIV-Positive Noncontrollers
- (2011) J. M. Shaw et al. JOURNAL OF VIROLOGY
- CD4+ T Cells, Including Th17 and Cycling Subsets, Are Intact in the Gut Mucosa of HIV-1-Infected Long-Term Nonprogressors
- (2011) E. J. Ciccone et al. JOURNAL OF VIROLOGY
- Border patrol: regulation of immunity, inflammation and tissue homeostasis at barrier surfaces by IL-22
- (2011) Gregory F Sonnenberg et al. NATURE IMMUNOLOGY
- Th17 cells and regulatory T cells in elite control over HIV and SIV
- (2011) Dennis J Hartigan-OʼConnor et al. Current Opinion in HIV and AIDS
- HIV-1 infection is characterized by profound depletion of CD161+ Th17 cells and gradual decline in regulatory T cells
- (2010) Andrew Prendergast et al. AIDS
- Evidence for the cure of HIV infection by CCR5 32/ 32 stem cell transplantation
- (2010) K. Allers et al. BLOOD
- Disruption of Intestinal CD4+ T Cell Homeostasis Is a Key Marker of Systemic CD4+ T Cell Activation in HIV-Infected Individuals
- (2010) S. N. Gordon et al. JOURNAL OF IMMUNOLOGY
- Differences in HIV Burden and Immune Activation within the Gut of HIV‐Positive Patients Receiving Suppressive Antiretroviral Therapy
- (2010) Steven A. Yukl et al. JOURNAL OF INFECTIOUS DISEASES
- The Detection of Acute HIV Infection
- (2010) Myron S. Cohen et al. JOURNAL OF INFECTIOUS DISEASES
- IL-22 defines a novel immune pathway of antifungal resistance
- (2010) A De Luca et al. Mucosal Immunology
- HIV Persistence and the Prospect of Long-Term Drug-Free Remissions for HIV-Infected Individuals
- (2010) D. Trono et al. SCIENCE
- Th17 cell dynamics in HIV infection
- (2010) Nichole R Klatt et al. Current Opinion in HIV and AIDS
- Biomarkers of immune dysfunction in HIV
- (2010) Daniel E Nixon et al. Current Opinion in HIV and AIDS
- HIV, mucosal tissues, and T helper 17 cells: where we come from, where we are, and where we go from here
- (2010) Donald L Sodora et al. Current Opinion in HIV and AIDS
- Evidence for a cross-talk between human neutrophils and Th17 cells
- (2009) M. Pelletier et al. BLOOD
- Incomplete Reconstitution of T Cell Subsets on Combination Antiretroviral Therapy in the AIDS Clinical Trials Group Protocol 384
- (2009) Gregory K. Robbins et al. CLINICAL INFECTIOUS DISEASES
- Th17 cytokines and host-pathogen interactions at the mucosa: Dichotomies of help and harm
- (2009) Janet Z. Liu et al. CYTOKINE
- Regulatory T Cells: Context Matters
- (2009) Herman Waldmann et al. IMMUNITY
- Cycling of gut mucosal CD4+ T cells decreases after prolonged anti-retroviral therapy and is associated with plasma LPS levels
- (2009) E J Ciccone et al. Mucosal Immunology
- α4+β7hiCD4+ memory T cells harbor most Th-17 cells and are preferentially infected during acute SIV infection
- (2009) M Kader et al. Mucosal Immunology
- Long-Term Control of HIV byCCR5Delta32/Delta32 Stem-Cell Transplantation
- (2009) Gero Hütter et al. NEW ENGLAND JOURNAL OF MEDICINE
- Critical Loss of the Balance between Th17 and T Regulatory Cell Populations in Pathogenic SIV Infection
- (2009) David Favre et al. PLoS Pathogens
- Emerging Concepts in the Immunopathogenesis of AIDS
- (2008) Daniel C. Douek et al. Annual Review of Medicine
- Differential Th17 CD4 T-cell depletion in pathogenic and nonpathogenic lentiviral infections
- (2008) J. M. Brenchley et al. BLOOD
- Incidence and Characterization of Acute HIV-1 Infection in a High-Risk Thai Population
- (2008) Jintanat Ananworanich et al. JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES
- Persistence of HIV in Gut‐Associated Lymphoid Tissue despite Long‐Term Antiretroviral Therapy
- (2008) Tae‐Wook Chun et al. JOURNAL OF INFECTIOUS DISEASES
- Antiviral Therapy during Primary Simian Immunodeficiency Virus Infection Fails To Prevent Acute Loss of CD4+ T Cells in Gut Mucosa but Enhances Their Rapid Restoration through Central Memory T Cells
- (2008) D. Verhoeven et al. JOURNAL OF VIROLOGY
- Altered balance between Th17 and Th1 cells at mucosal sites predicts AIDS progression in simian immunodeficiency virus-infected macaques
- (2008) V Cecchinato et al. Mucosal Immunology
- Induction and effector functions of TH17 cells
- (2008) Estelle Bettelli et al. NATURE
- Simian immunodeficiency virus–induced mucosal interleukin-17 deficiency promotes Salmonella dissemination from the gut
- (2008) Manuela Raffatellu et al. NATURE MEDICINE
- Microbial Translocation Is Associated with Increased Monocyte Activation and Dementia in AIDS Patients
- (2008) Petronela Ancuta et al. PLoS One
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now