Clostridium difficile 027/BI/NAP1 Encodes a Hypertoxic and Antigenically Variable Form of TcdB

Clostridium difficile Ribotype Does Not Predict Severe Infection

(2012) Seth T. Walk et al.   CLINICAL INFECTIOUS DISEASES

Changing Epidemiology of Clostridium difficile Infection Following the Introduction of a National Ribotyping-Based Surveillance Scheme in England

(2012) M. H. Wilcox et al.   CLINICAL INFECTIOUS DISEASES

A Chimeric Toxin Vaccine Protects against Primary and Recurrent Clostridium difficile Infection

(2012) Haiying Wang et al.   INFECTION AND IMMUNITY

Association of Relapse of Clostridium difficile Disease with BI/NAP1/027

(2012) J. W. Marsh et al.   JOURNAL OF CLINICAL MICROBIOLOGY

TcdB from hypervirulent Clostridium difficile exhibits increased efficiency of autoprocessing

(2012) Jordi M. Lanis et al.   MOLECULAR MICROBIOLOGY

The Epidemiology of Community-Acquired Clostridium difficile Infection: A Population-Based Study

(2011) Sahil Khanna et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Incidence of and risk factors for community-associated Clostridium difficile infection: A nested case-control study

(2011) Jennifer L Kuntz et al.   BMC INFECTIOUS DISEASES

Lack of Association between Clinical Outcome of Clostridium difficile Infections, Strain Type, and Virulence-Associated Phenotypes

(2011) S. Sirard et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Systemic Dissemination of Clostridium difficile Toxins A and B Is Associated With Severe, Fatal Disease in Animal Models

(2011) Jennifer Steele et al.   JOURNAL OF INFECTIOUS DISEASES

The Repetitive Oligopeptide Sequences Modulate Cytopathic Potency but Are Not Crucial for Cellular Uptake of Clostridium difficile Toxin A

(2011) Alexandra Olling et al.   PLoS One

Reconsidering the Sporulation Characteristics of Hypervirulent Clostridium difficile BI/NAP1/027

(2011) David A. Burns et al.   PLoS One

The Anti-Sigma Factor TcdC Modulates Hypervirulence in an Epidemic BI/NAP1/027 Clinical Isolate of Clostridium difficile

(2011) Glen P. Carter et al.   PLoS Pathogens

Global Epidemiology of Clostridium difficile Infection in 2010

(2010) Dale N. Gerding   INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY

Human Hypervirulent Clostridium difficile Strains Exhibit Increased Sporulation as Well as Robust Toxin Production

(2010) M. Merrigan et al.   JOURNAL OF BACTERIOLOGY

A review of mortality due to Clostridium difficile infection

(2010) J.A. Karas et al.   JOURNAL OF INFECTION

Variations in TcdB Activity and the Hypervirulence of Emerging Strains of Clostridium difficile

(2010) Jordi M. Lanis et al.   PLoS Pathogens

Clostridium difficile Strain NAP-1 Is Not Associated With Severe Disease in a Nonepidemic Setting

(2009) Jeffrey Cloud et al.   Clinical Gastroenterology and Hepatology

Clostridium difficile Infection Caused by the Epidemic BI/NAP1/027 Strain

(2009) Jennifer R. O'Connor et al.   GASTROENTEROLOGY

Toxin B is essential for virulence of Clostridium difficile

(2009) Dena Lyras et al.   NATURE

Comparative genome and phenotypic analysis of Clostridium difficile 027 strains provides insight into the evolution of a hypervirulent bacterium

(2009) Richard A Stabler et al.   GENOME BIOLOGY

The Case for Vancomycin as the Preferred Drug for Treatment ofClostridium difficileInfection

(2008) John G. Bartlett   CLINICAL INFECTIOUS DISEASES

Increased Sporulation Rate of Epidemic Clostridium difficile Type 027/NAP1

(2008) T. Akerlund et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Comparative analysis of BI/NAP1/027 hypervirulent strains reveals novel toxin B-encoding gene (tcdB) sequences

(2008) R. A. Stabler et al.   JOURNAL OF MEDICAL MICROBIOLOGY

Clinical Severity of Clostridium difficile PCR Ribotype 027: A Case-Case Study

(2008) Oliver W. Morgan et al.   PLoS One

Structure and mode of action of clostridial glucosylating toxins: the ABCD model

(2008) Thomas Jank et al.   TRENDS IN MICROBIOLOGY