Identification of Two Legionella pneumophila Effectors that Manipulate Host Phospholipids Biosynthesis

Domain organization of Legionella effector SetA

(2012) Thomas Jank et al.   CELLULAR MICROBIOLOGY

Reversible phosphocholination of Rab proteins byLegionella pneumophilaeffector proteins

(2012) Philip R Goody et al.   EMBO JOURNAL

Legionella pneumophila LidA Affects Nucleotide Binding and Activity of the Host GTPase Rab1

(2012) M. R. Neunuebel et al.   JOURNAL OF BACTERIOLOGY

Pho85p-Pho80p Phosphorylation of Yeast Pah1p Phosphatidate Phosphatase Regulates Its Activity, Location, Abundance, and Function in Lipid Metabolism

(2012) Hyeon-Son Choi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural Insights into a Unique Legionella pneumophila Effector LidA Recognizing Both GDP and GTP Bound Rab1 in Their Active State

(2012) Wei Cheng et al.   PLoS Pathogens

Manipulation of host vesicular trafficking and innate immune defence by Legionella Dot/Icm effectors

(2011) Jianning Ge et al.   CELLULAR MICROBIOLOGY

Phospholipase D: Enzymology, Functionality, and Chemical Modulation

(2011) Paige E. Selvy et al.   CHEMICAL REVIEWS

Protein kinase D: coupling extracellular stimuli to the regulation of cell physiology

(2011) Ya Fu et al.   EMBO REPORTS

Characterisation of Legionella pneumophila phospholipases and their impact on host cells

(2011) Christina Lang et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

The Coxiella burnetii Cryptic Plasmid Is Enriched in Genes Encoding Type IV Secretion System Substrates

(2011) D. E. Voth et al.   JOURNAL OF BACTERIOLOGY

The Conserved YAGL Motif in Human Metapneumovirus Is Required for Higher-Order Cellular Assemblies of the Matrix Protein and for Virion Production

(2011) Y. Sabo et al.   JOURNAL OF VIROLOGY

Diacylglycerol kinase ζ controls diacylglycerol metabolism at the immunological synapse

(2011) Severine I. Gharbi et al.   MOLECULAR BIOLOGY OF THE CELL

Legionella pneumophila SidD is a deAMPylase that modifies Rab1

(2011) Yunhao Tan et al.   NATURE

Modulation of Rab GTPase function by a protein phosphocholine transferase

(2011) Shaeri Mukherjee et al.   NATURE

Comprehensive Identification of Protein Substrates of the Dot/Icm Type IV Transporter of Legionella pneumophila

(2011) Wenhan Zhu et al.   PLoS One

Legionella pneumophila regulates the small GTPase Rab1 activity by reversible phosphorylcholination

(2011) Y. Tan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Host Proteasomal Degradation Generates Amino Acids Essential for Intracellular Bacterial Growth

(2011) C. T. D. Price et al.   SCIENCE

De-AMPylation of the Small GTPase Rab1 by the Pathogen Legionella pneumophila

(2011) M. R. Neunuebel et al.   SCIENCE

Shaping up the membrane: diacylglycerol coordinates spatial orientation of signaling

(2011) María Almena et al.   TRENDS IN BIOCHEMICAL SCIENCES

The Coxiella burnetii Dot/Icm System Creates a Comfortable Home through Lysosomal Renovation

(2011) H. J. Newton et al.   mBio

Dot/Icm Type IVB Secretion System Requirements for Coxiella burnetii Growth in Human Macrophages

(2011) P. A. Beare et al.   mBio

The Coxiella burnetii Dot/Icm System Delivers a Unique Repertoire of Type IV Effectors into Host Cells and Is Required for Intracellular Replication

(2011) Kimberly L. Carey et al.   PLoS Pathogens

Comparative and Functional Genomics of Legionella Identified Eukaryotic Like Proteins as Key Players in Host?Pathogen Interactions

(2011) Laura Gomez-Valero et al.   Frontiers in Microbiology

Effector Glycosyltransferases in Legionella

(2011) Yury Belyi et al.   Frontiers in Microbiology

Modulation of Host Cell Function byLegionella pneumophilaType IV Effectors

(2010) Andree Hubber et al.   Annual Review of Cell and Developmental Biology

Lipins: Multifunctional Lipid Metabolism Proteins

(2010) Lauren S. Csaki et al.   Annual Review of Nutrition

The Legionella pneumophila F-box protein Lpp2082 (AnkB) modulates ubiquitination of the host protein parvin B and promotes intracellular replication

(2010) M. Lomma et al.   CELLULAR MICROBIOLOGY

LnaB: a Legionella pneumophila activator of NF-κB

(2010) Vicki P. Losick et al.   CELLULAR MICROBIOLOGY

The E Block motif is associated with Legionella pneumophila translocated substrates

(2010) Li Huang et al.   CELLULAR MICROBIOLOGY

Molecular Pathogenesis of Infections Caused by Legionella pneumophila

(2010) H. J. Newton et al.   CLINICAL MICROBIOLOGY REVIEWS

Indispensable Role for the Eukaryotic-Like Ankyrin Domains of the Ankyrin B Effector of Legionella pneumophila within Macrophages and Amoebae

(2010) C. T. D. Price et al.   INFECTION AND IMMUNITY

E3 Ubiquitin Ligase Activity and Targeting of BAT3 by Multiple Legionella pneumophila Translocated Substrates

(2010) A. W. Ensminger et al.   INFECTION AND IMMUNITY

Exploitation of conserved eukaryotic host cell farnesylation machinery by an F-box effector ofLegionella pneumophila

(2010) Christopher T.D. Price et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Large-scale identification and translocation of type IV secretion substrates by Coxiella burnetii

(2010) C. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Legionella Effector Protein DrrA AMPylates the Membrane Traffic Regulator Rab1b

(2010) M. P. Muller et al.   SCIENCE

Coordination of Golgi functions by phosphatidylinositol 4-kinases

(2010) Todd R. Graham et al.   TRENDS IN CELL BIOLOGY

Legionella Metaeffector Exploits Host Proteasome to Temporally Regulate Cognate Effector

(2010) Tomoko Kubori et al.   PLoS Pathogens

Intracellular Life of Coxiella burnetii in Macrophages

(2009) Eric Ghigo et al.   Annals of the New York Academy of Sciences

Molecular mechanism of elongation factor 1A inhibition by aLegionella pneumophilaglycosyltransferase

(2009) Ramon Hurtado-Guerrero et al.   BIOCHEMICAL JOURNAL

Targeting eEF1A by aLegionella pneumophilaeffector leads to inhibition of protein synthesis and induction of host stress response

(2009) Xihui Shen et al.   CELLULAR MICROBIOLOGY

ALegionellaeffector acquired from protozoa is involved in sphingolipids metabolism and is targeted to the host cell mitochondria

(2009) Elena Degtyar et al.   CELLULAR MICROBIOLOGY

A Legionella type IV effector activates the NF- B pathway by phosphorylating the I B family of inhibitors

(2009) J. Ge et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lipins, Lipids and Nuclear Envelope Structure

(2009) Symeon Siniossoglou   TRAFFIC

Genome-Scale Identification of Legionella pneumophila Effectors Using a Machine Learning Approach

(2009) David Burstein et al.   PLoS Pathogens

TheLegionella pneumophilaphosphatidylinositol-4 phosphate-binding type IV substrate SidC recruits endoplasmic reticulum vesicles to a replication-permissive vacuole

(2008) Curdin Ragaz et al.   CELLULAR MICROBIOLOGY

Large-scale identification ofLegionella pneumophilaDot/Icm substrates that modulate host cell vesicle trafficking pathways

(2008) Matthew Heidtman et al.   CELLULAR MICROBIOLOGY

The inositol polyphosphate 5-phosphatase OCRL1 restricts intracellular growth ofLegionella, localizes to the replicative vacuole and binds to the bacterial effector LpnE

(2008) Stefan S. Weber et al.   CELLULAR MICROBIOLOGY

Characterization of the YeastDGK1-encoded CTP-dependent Diacylglycerol Kinase

(2008) Gil-Soo Han et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Rab1 Guanine Nucleotide Exchange Factor SidM Is a Major Phosphatidylinositol 4-Phosphate-binding Effector Protein ofLegionella pneumophila

(2008) Eva Brombacher et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

An Unconventional Diacylglycerol Kinase That Regulates Phospholipid Synthesis and Nuclear Membrane Growth

(2008) Gil-Soo Han et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

SopB promotes phosphatidylinositol 3-phosphate formation onSalmonellavacuoles by recruiting Rab5 and Vps34

(2008) Gustavo V. Mallo et al.   JOURNAL OF CELL BIOLOGY

The Salmonella SPI-2 effector SseJ exhibits eukaryotic activator-dependent phospholipase A and glycerophospholipid : cholesterol acyltransferase activity

(2008) N. S. Lossi et al.   MICROBIOLOGY-SGM

Legionella translocates an E3 ubiquitin ligase that has multiple U-boxes with distinct functions

(2008) Tomoko Kubori et al.   MOLECULAR MICROBIOLOGY

Esterification of cholesterol by a type III secretion effector during intracellular Salmonella infection

(2008) Parwez Nawabi et al.   MOLECULAR MICROBIOLOGY

Membrane lipids: where they are and how they behave

(2008) Gerrit van Meer et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Ankyrin Repeat Proteins Comprise a Diverse Family of Bacterial Type IV Effectors

(2008) X. Pan et al.   SCIENCE